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Examinations in Chronic Abdominal Conditions
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Pain present in the right hypochondriac, epigastric, or left hypochondriac region depending on location of the tumour. Back pain when it is present is due to involvement of retropancreatic nerves, or pancreatic duct obstruction or stasis.
Diarrhoea, steatorrhoea, silvery stool (due to undigested fat mixing with metabolized blood which is derived from the ooze of periampullary growth); loss of appetite and weight; scratch marks on the back.
Migratory superficial thrombophlebitis— Trousseau’s sign (10%) is due to release of platelet
aggregating factors from the tumour or its necrotic material (Trousseau himself died of carcinoma pancreas who had migrating thrombophlebitis).
Ascites; Left supraclavicular palpable lymph node; secondaries in rectovesical pouch (Blumer’s shelf).
Gallbladder may be palpable which is nontender, soft, globular, smooth, moving with respiration, mobile horizontally, dull on percussion. Courvoisier law favours gallbladder enlargement.
Liver is enlarged, smooth, firm, nontender , due to dilated bile filled biliary radicles—Hydrohepatosis. Liver can show multiple hard nodules due to secondaries.
Cystadenocarcinoma of pancreas can present with mass in epigastric region, which is nonmobile, not moving with respiration, smooth, soft, nontender.
Splenic vein thrombosis with splenomegaly (10%) can occur.
Hirschsprung’s Disease
It is a congenital, familial condition occurring in newborn due to the absence of ganglion cells— Auerbach’s and Meissner’s plexus in anorectum, which may extend proximally either a part or full length of the colon.
Types:
It has got three zones: 1. Distal immobile spastic segment, i.e. aganglionic zone; 2. A proximal, middle transitional zone of about 1-5 cm length with less,
sparse number of ganglions (cone); 3. A still more proximal, hypertrophied dilated segment is actually the normal ganglionic area.
Clinical features: It is common in males. In 90% of cases symptoms appear in early neonatal period, i.e. within three days of birth. Present with complaints of failure of passage of meconium. After introducing finger into the rectum child passes toothpaste like stool, with evidence of straining. Distension of the abdomen with features of intestinal obstruction is seen. Constipation with history of passing stools once in 3-4 days with straining, is seen throughout the childhood and also in adolescent period. Occasionally condition can cause intestinal obstruction.
Diagnosis: History of failure of passing meconium. Plain X-ray abdomen—shows intestinal obstruction. Biopsy from all three zones is taken to study the ganglions and hypertrophic nerve terminals in spasmodic segment. Barium enema is done to look for the extent of disease and three zones. Foley’s catheter should not be used while doing barium enema in case of Hirschsprung’s disease. Anorectal mano- metry—shows the absence of rectoanal reflex in Hirschsprung’s disease, which is diagnostic.
Complications: Colitis; intestinal obstruction; growth retardation; constipation.
Differential diagnosis: Total neuronal dysplasia; Acquired megacolon; anorectal malformation.
Ulcerative Colitis
An inflammatory condition of rectum and colon of unknown aetiology perhaps related to stress, westerni­sed diet, autoimmune factor, familial tendency , allergic factor . Disease commonly starts in the rectum, spreads proximally to the colon and often into the ileum as back wash ileitis.
Pathology: To begin with, multiple minute ulcers occurs, with proctitis and colitis These ulcers extends into the deeper layer Spasm of the bowel Stricture of the colon Permanently contracted
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colon → In between ulcers, epithelial thickening occurs which appears like polyps Pseudopolyposis.
Clinical features: More common in females, begins in 3rd decade. Watery diarrhoea, mucous or blood stained discharge per rectum; colicky pain, spasms; decreased appetite and loss of weight; relapses and remissions at regular intervals. Two types of presentations: (a) Fulminant type—5% common. It is a severe form, with continuous diarrhoea with passage of blood, mucous and pus. Patient is ill and dehydrated; mimics fulminant amoebic colitis, severe typhoid and dysentery. Later abdominal distension occurs. May go for acute toxic dilatation (1.5%) of transverse colon where in the diameter of transverse colon > 6 cm. It has high mortality and requires emergency sur gery , i.e. either colostomy or resection with ileostomy and later ileoanal anastomosis. (b) Chronic type: (95%) Lasts for months and years with diarrhoea, blood loss, anaemia, invalidism, abdominal discomfort and pain.
Investigations: (a) Barium enema—shows loss of haustrations, narrow contracted colon (hose pipe
colon), mucosal changes, pseudopolyps. It is avoided in fulminant cases. (b) Sigmoidoscopy and biopsy. Colonoscopy also is required. Due to very high incidence of malignant transformation in ulcerative colitis (10-20%), multiple biopsies should be taken from suspected ar eas of the colon. Risk increases with
age of the patient and duration of the disease (20%). Complications: Pseudopolyposis; turning into malig-
nancy; stricture formation commonly in rectosigmoid and anal canal; toxic megacolon in transverse colon; massive haemorrhage; fistula in ano; liver cirrhosis (50%); skin lesions; arthritis; iritis, ankylosing spon­dylitis; sclerosing cholangitis, carcinoma of gall­bladder.
Familial Adenomatous Polyp (FAP)
It is inherited as an autosomal dominant neoplastic condition (chromosome no.5). Incidence is equal in both sex, involving commonly the large intestine but can also occur in stomach, duodenum and small intestine. It is familial with a high potential for malig- nant transformation. It can be associated with duodenal
or ampullary carcinomas, Gardner’s syndrome (Des- moid tumour in the abdomen, osteomas (75%) and epidermoid cysts) and also Turcot’s syndrome (FAP + brain tumour (medulloblastoma or gliomas). It presents in younger age group - 15-20 years; usually multiple (over 100); presents with lower abdominal pain, loose stools with blood and mucous, weight loss. If there is no adenoma at the age of 30 years, then it is not FAP of colon.
Carcinoma Colon
It is commonly adenocarcinoma. Very rarely adeno- squamous, squamous carcinoma can occur.
Adenocarcinoma: Sigmoid colon (21%) is the commonest site of malignancy after rectum (38%). In caecum it is 12% common.
Aetiology: Diet: Red meat and saturated fat increases the incidence of colonic cancer. Cholesterol increases the bile acid concentration in the intestinal lumen which acts as cocarcinogen. High fibre diet protects the colon against cancer. Genetic: Carcinoma colon is more common in individuals with adenoma colon or with familial adenomatous polyposis—F AP or with long standing ulcerative colitis. Alcohol and cigarette smoking increases the risk. Aspirin and other NSAIDs
protect against colonic cancer.
Types: Patient can have de novo multiple primary carcinomas in different parts of the colon at same time, i.e. synchronous (5%), or can present with growth in different parts of the colon in different periods, i.e. metachronous (2-5%). Gross types: Annular (stenosing)—It is more common on left side. T ubular; Ulcerative (common on right side); Cauliflower-like. Here the growth spreads round the internal wall and so it often presents with intestinal obstruction.
Spread: Locally it can invade the bladder, obstruct ureter and so cause hydronephrosis. It can perforate and cause peritonitis/ pericolic abscess/ faecal fistula. Growth may get adherent to psoas muscle posteriorly. Growth through lymphatics spreads to pericolic, epicolic, intermediate and principal group of lymph nodes; 40% of carcinoma colon spreads to liver via
portal veins. Secondaries may be either solitary or multiple, presents as enlarged liver with hard, umbi- licated nodules. Rarely it spreads to bone, lung, skin.
Examinations in Chronic Abdominal Conditions
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Clinical features: It occurs usually after 50 years. Familial type can present in younger age group. Commonly presents with loss of appetite and weight, anaemia, abdominal discomfort and mass per abdo­men. 20% of cases presents as an acute intestinal obstruction. Right sided growth commonly presents with anaemia, palpable mass in the right iliac fossa, which is not moving with respiration, mobile, nonten­der, hard, well localised with impaired resonant note. Carcinoma caecum occasionally can present like acute appendicitis or intussusception with intestinal obstruc­tion. Left sided growth presents with colicky pain,
altered bowel habits (alternating constipation and
diarrhoea), palpable lump, and distension of abdomen
due subacute/chr onic obstruction. Later may present like complete colonic obstruction. Tenesmus, with passage of blood and mucous, with alternate consti­pation and diarrhoea, is common. Bladder symptoms may warn colovesical fistula. Enlarged liver with multiple umbilicated hard secondaries, ascites, rectovesical secondaries, palpable left supraclavicular lymph nodes are other presentations. Faecal strength of Streptococcus bovis bacteria increases many fold in colonic cancer patients compared to individuals without colonic cancer.
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Examination of
21
In a patient presenting with abdominal mass, generally following history should be elicited carefully.
Pain: Site, nature, aggravating or relieving factors, duration of pain, referred pain.
Vomiting: Type, content, haematemesis, relation to food, frequency.
Jaundice: It is an important factor in relation to liver, gallbladder or pancreatic masses.
Bowel habits: Constipation, diarrhoea, bloody diar­rhoea, furious diarrhoea, tenesmus.
Decreased appetite and weight. Inspection of the mass: Anatomical location, mar gin,
surface, movement with respiration. Palpation of the mass: Site, extent, surface, tenderness,
consistency, movement with respiration, mobility, borders, plane of the swelling (by leg rising test), presence of other masses.
Mass Abdomen
Pervaginal examination: It is done to assess pelvic masses.
Abdomen is divided into nine regions by four lines
(Fig. 21.1).
Upper horizontal or transpyloric line is midway between the suprasternal notch and symphysis pubis or line between tips of ninth costal cartilages on each side. It is often midway between xiphisternum and umbilicus.
Lower horizontal line is transtubercular line at the level of two tubercles (5 cm behind the anterior superior iliac spine along the iliac crest) on the iliac crest.
Right vertical line is the line through the midpoint of right anterior superior iliac spine and pubic symphysis. It is usually a line joining right midclavi­cular and right midinguinal points.
Left vertical line is the line through the midpoint of left anterior superior iliac spine and pubic symphysis. It is usually a line joining left midclavicular and left midinguinal points.
Percussion: It is an important aspect of examination in case of an abdominal mass. Percussion over the mass is important to determine the anatomical location of the mass. If mass is dull, then it lies in the anterior abdominal wall or intra-abdominally in front of the bowel, liver, spleen, gallbladder, etc. If the mass is with an impaired resonant note, then the mass is arising from the bowel like stomach, colon, and small bowel. If the mass is resonant on percussion, then the mass is probably in the retroperitoneal region. Other than this, liver dullness, free fluid in the abdomen should be elicited during percussion.
Per-rectal examination: It is done to look for any secondaries in rectovesical pouch, any primary tumour or relation of lower abdomen masses (pelvic masses).
Fig. 21.1: Different regions in the abdomen.
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Regions in the abdomen
Right hypochondrium Epigastrium Left hypochondrium Right lumbar region Umbilical region Left lumbar region Right iliac fossa Hypogastrium Left iliac fossa
Quadrants in the abdomen are four in number formed by two lines—one is vertical midline through the umbilicus; another is horizontal line passing through the umbilicus. Quadrants are—right upper, right lower, left upper and left lower (Fig. 21.2).
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• Yellowish discolouration of sclera—duration
• Loss of appetite and decreased weight—weight
loss more than 10 Kg in short period/6 months is
significant
• Altered bowel habits/constipation/diarrhoea
• Fever—Its character is important to be noted in
abdominal tuberculosis, amoebic liver abscess,
cholangitis, malignancy with tumour necrosis,
infected pseudocyst of pancreas.
History
History of Present Illness
Pain
Site of origin of pain; onset (sudden/insidious); duration; radiation of pain/referred pain; type of pain— intermittent/persistent; dull, severe pricking, colicky; periodicity with an interval of free period—ulcer pain has often got periodicity unless it is complicated; relation to food intake—more/less/not related to meals; relation to vomiting/induced vomiting; aggravating/ relieving factors; pain in relation to bowel habits/ urinary habits.
Fig. 21.2: Different quadrants in the abdomen. They are four in number formed by two lines—one is vertical midline through the umbilicus; another is horizontal line passing through the umbilicus. Quadrants are—right upper, right lower, left upper and left lower.
Chief Complaints
• Mass per abdomen—ask for duration, progress, site, mass appearing/disappearing (like in intussus­ception, Dietl’s crisis of hydronephrosis kidney, and choledochal cyst)
• Pain in the abdomen—region of pain; duration of pain to be mentioned
• Vomiting—duration
• Haematemesis, malaena—duration
• Satiety—sensation of fullness after taking food (early satiety signifies gastrointestinal pathology like carcinomas
Vomiting
• Duration, frequency, relation to food, type (projectile/effortless)
• Vomitus—content (food/blood/bile), quantity, smell, colour—coffee ground/bloody/yellow , taste
• Relation to pain, details of haematemesis if present
• It is better to ask the patient to collect and keep the vomitus and clinician should personally observe it.
Jaundice
• Duration, colour (greenish yellow suggests obstruction), severity, progress (progressive/ intermittent/static/reducing)
• Presence of fever with jaundice—cholangitis
• Association with pruritus, clay coloured stool/ silvery stool.
Altered Bowel Habits
• Duration, type, malaena, with distension of abdomen
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Altered Urinary Symptoms
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History of frequency/urgency/haematuria/pyuria/ oliguria/painful urination/burning urine/difficulty in passing urine/hesitancy/hiccough/oedema feet or face; relation of urinary symptoms to pain, mass in abdomen should be asked for.
Other Relevant History
Cough and haemoptysis, bone pain, etc.—suggestive of metastases.
Past History
Earlier history of abdominal surgery—reason for surgery, how long ago it was done, whether earlier symptoms are relieved or not, whether the symptoms are now similar or different, whether it was an emer­gency or an elective surgery, whether it was earlier properly investigated or not, whether drain was placed or not—if placed when it was removed; what content was coming through the drain, whether blood trans­fusion was done during surgery or in postoperative period.
A
Personal History
History of alcohol intake, diet, smoking, etc. has to be noted.
T reatment history—any relevant history of surgery in the past, chemotherapy for malignancies, abdominal tuberculosis treated, and so on.
Family history—any relevant history in the family should be taken as some GI malignancies run in families.
General Examination
Pallor/jaundice/clubbing/oedema feet /cachexia is noted. Pulse/blood pressure is recorded. Genitalia/ respiratory and cardiovascular system should be examined (Figs 21.3A and B).
Local Abdominal Examination
Inspection
Inspection of the abdomen is done in supine position exposed from midchest to midthigh region with arms extended. Inspection is done from side of the bed as
B
Figs 21.3A and B: Obstructive jaundice in a patient with
carcinoma head of pancreas. Note the sclera for discoloration. Severe itching is common in these patients.
well as from foot end with eye level at the level of the patient (Figs 21.4A to 21.5B).
Shape of the abdomen—contour—normal/scap-
hoid/distended.
Skin over the abdomen whether stretched/pigmen-
ted; presence of scar whether healed primarily or secondarily; site of scar; length and width of scar; whether there is any incisional hernia or not.
Dilated veins over the abdomen should be looked
for—caput medusae is dilated veins radiating from the umbilicus—seen in portal hypertension. In inferior vena caval obstruction (lateral abdominal wall) dilated veins are visible with their flow of blood from below upwards towards superior vena cava. In superior vena caval obstruction dilated veins are visible with blood flow from above downwards. Dilated veins should be inspected in standing position and also
Examination of Mass Abdomen
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A
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B
Figs 21.4A and B: Proper exposure of the abdomen is
important from midchest to midthigh and position of the patient for proper abdominal examination.
A
B
Figs 21.5A and B:Inspection of the abdomen should be
done at the level of the patient’s abdomen both from right side as well as from foot end.
direction of flow should be checked by placing two fingers apart over the vein and the fingers are released one by one to see the direction of blood flow . Normally abdominal wall drains to superior vena cava above the umbilicus and to inferior vena cava below the umbi­licus—water shed area (Figs 21.6 and 21.7A and B).
Movements of regions with respiration should be
noted.
Fig. 21.6: Superior vena caval obstruction causing dilated veins in the neck chest wall and shoulder. Note the neck swelling extending into the mediastinum.
A
Figs 21.7A and B: Inferior vena caval obstruction causing
dilated veins over the lateral aspect of the flank with flow of blood upwards.
B
Pulsations over the mass or any region should be
noted. Patient should hold the breath after full expiration to see for pulsations.
Any visible peristalsis should be looked for—
V isible gastric peristalsis (VGP) is seen in upper middle region with waves beginning from left upper abdomen directed downwards and towards right to umbilical region. It is stimulated by drinking glass of water or by massaging the epigastrium. It signifies gastric outlet obstruction. But may be absent in gastric outlet obstruction where gastric paresis develops and stomach becomes dilated and silent without any motility . Visible intestinal peristalsis (VIP) occurs in step ladder pattern in central abdomen from left to right or vice versa
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in umbilical region. Visible colonic peristalsis may be obvious from right to left along the line of colon
Inspection of the mass—Its location (exact location should be mentioned as in which region it is located and then its extension into the other region should be mentioned later); extent; approximate size; well defined or ill defined (often mass is not clearly seen but fullness is visible); margins whether clear or not or which part is clear and which part is not; presence of movement of mass with respiration or not (upper abdomen mass like liver, stomach, spleen, gallbladder , omental mass, kidney mass moves with respiration). Mass which was initially mobile may not be mobile later once it gets fixed to retroperitoneum or deeper plane. But occasionally mass which was initially not mobile, may start moving with respiration once gets attached to structures like omentum. Lower abdominal mass, retroperitoneal mass will not usually move with respiration. Mass which comes in close contact with diaphragm will move with respiration. Composite mass may move with respiration because of its component like omentum, lymph nodes, bowel, etc (Figs 21.8
to 21.10).
Fig. 21.9: Large secondaries in liver. Patient has undergone enucleation of left eye (with artificial eye) for primary melanoma choroids—15 years ago. Now he has presented with late large liver secondaries.
Umbilicus—Position is noted. It may be everted/ inverted. Tanyol sign: Umbilicus is shifted upwards in pelvic/ovarian mass and downwards in ascites. Sister Joseph nodules can occur in the umbilicus as secondaries from abdominal GI malignancies through ligamentum teres. Umbilical black eye is Cullen’ s sign of discolouration of umbilicus seen in acute pan­creatitis. Umbilical concretions, umbilical discharge
Fig. 21.8: Visible large upper abdomen mass—could be enlarged liver/pseudocyst of pancreas/retroperitoneal mass.
Fig. 21.10: Head raising test should be done to find out whether mass is intra-abdominal or in the abdominal wall.
(sinus/fistula), bluish tinge in ruptured ectopic gestation (Cullen’s), yellow tinge around umbilicus in acute pancreatitis in women (Johnston)—should be observed (Fig. 21.11).
Hernial orifices and genitalia inspection—is a must. Scrotum should be examined for testicular tumour/
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Fig. 21.11: Sister Joseph secondary nodule in the
umbilicus.
Fig. 21.12: Impulse on coughing should be seen and
also felt to confirm associated hernia.
loss of testicular sensation as testicular tumour may present as epigastric mass due to enlarged para-aortic lymph nodes (Figs 21.12 and 21.13).
Palpation
While palpating the abdomen patient should take deep breath with mouth open to relax the abdomen otherwise it is difficult to get proper finding. Hands should be warm and forearm should be horizontal at the same level as patient’s abdomen. Palpation is done with ventral aspect of the fingers. Legs should be partially flexed at hips and knees.
Fig. 21.13: Loin should be inspected from behind for
fullness and oedema.
Local rise of temperature is checked using back
of hand. It suggests inflammatory pathology.
T enderness over the abdomen or over the mass must be noted. It may be due to inflammatory pathology. Often malignant condition may cause tenderness either due to secondary infection or due to tumour necrosis.
Position, size, shape, and surface of the mass:
Nodular surface may be neoplastic; smooth surface may be of benign or inflammatory pathology.
Margin: Well-defined margin which is distinct may be a feature of neoplasm. Ill-defined margin may be seen in inflammatory or traumatic pathology. Mar gin which is indistinct whether upper or lower should be confirmed. In the upper abdomen feeling the upper margin is important. In liver mass upper margin is not felt but it is felt in stomach mass. Upper margin of the mass may be difficult to feel in mass from fundus of stomach. Feeling the lower margin is important in the lower abdomen mass . If lower margin is not clear one has to find out whether mass is extending to pelvis or not. Rectal or per vaginal examination confirms the pelvic mass. Often full bladder may interfere or mimic the mass and so mass should be palpated again after emptying the bladder, if needed after passing
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a urinary catheter. Margin may be better felt with change in position either sitting, standing, or lateral position.
Mobility of the mass: Mass is held between thumb and fingers and moved in vertical and horizontal directions. If there is restriction in movement, which movement is restricted should be checked. T otally fixed mass will not be mobile at all.
During inspiration (on deep breathing) mass moves down to touch the hand of the examiner kept on the lower margin of the mass. During expiration it moves back to its original position (Figs 21.14 to 21.16).
Fig. 21.14: Checking the temperature of the abdomen
using dorsum of the hand.
Fig. 21.16: Lower abdominal mass—retroperitoneal
tumour/ovarian tumour/uterine mass.
taut. Raising both legs straight above the bed (Carnett’s test) can also be used for the same. Air is tried to be blow out by holding the nose tightly with fingers and mouth shut—V alsalva manoeuvre. Abdominal wall mass will become prominent and immobile during these manoeuvre.
Fig. 21.15: Palpation of abdominal mass using fingers.
Head raising test or leg raising test (Carnett’ s test):
It is done to confirm whether mass is in the abdominal wall or intra-abdominal. Mass is seen initially and palpated and patient is asked to raise his head along with shoulders with arms folded over the chest. If mass disappears or becomes smaller, it is intra-abdominal mass; if becomes more prominent it is in the abdominal wall. Manoeuvre is done to make the abdominal muscle
Palpation of Liver
Liver is palpated by placing flat of the hand parallel to the right costal margin—initially near right iliac fossa with fingers directed upwards up to the margin of the right rectus. Slowly with each phase of respiration fingers should be moved upwards towards right hypochondrium to feel the lower margin of the liver. The surface of the liver is then felt for tenderness, nodularity , round/sharp margin. Level of lower margin should be measured in centimeters from right costal margin. In children below 3 years, liver is palpable 3 cm below the right costal margin. Liver is not palpable or just palpable in normal adult. Whenever there is ascites liver is palpated by ‘dip method’ - (dipping fingers quickly so as to displace the fluid). Liver may be enlarged upwards in hydatid cyst, and liver abscess (Figs 21.17A to C).
Normal liver span in adult is (vertical height) 12­15 cm. Liver span in infant is 2.4-2.8 cm. At the age of 14 years it is 5.5-7.5 cm.