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Pharmaceutical Organic Chemistry
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Pharmaceutical
Organic Chemistry
S. K. Bhasin
FICCE, FICC, FIAEM, FIJEP
Global Research Institute of Management and Technology
Radaur, Distt. Yamuna Nagar, Haryana
Rajshree Khare
FICC, FISCA, FIANCAS (BARK)
Head and Professor
Department of Chemistry, MM University, Mullana, Haryana
Reena Gupta
Senior Lecturer
Department of Chemistry, Maharishi Ved Vyas Engineering College
Jagadhri, Haryana
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Pharmaceutical Organic Chemistry
Bhasin, Khare and Gupta
ELSEVIER
A division of
Reed Elsevier India Private Limited
Mosby, Saunders, Churchill Livingstone, Butterworth Heinemann and Hanley & Belfus are the Health Science imprints of Elsevier.
© 2012 Elsevier
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical including photocopying, recording, or any information storage and retrieval system without the prior written permission from the publisher and the copyright holder.
ISBN: 978-81-312-2800-5
Medical knowledge is constantly changing. As new information becomes available, changes in treatment, pro­cedures, equipment and the use of drugs become necessary. The authors, editors, contributors and the publisher have, as far as it is possible, taken care to ensure that the information given in this text is accurate and up-to-date.
However, readers are strongly advised to conrm that the information, especially with regard to drug dose/usage,
complies with current legislation and standards of practice. Please consult full prescribing information before issuing prescriptions for any product mentioned in the publication.
Published by Elsevier, a division of Reed Elsevier India Private Limited
Registered ofce: 305, Rohit House, 3, Tolstoy Marg, New Delhi-110001, India Corporate ofce: 14th Floor, Building No. 10B, DLF Cyber City, Phase II, Gurgaon-122002, Haryana, India
Publishing Manager: Ritu Sharma Development Editor: Subodh K. Chauhan Copy Editors: Ankush Kumar and Saroj Sahu Manager Publishing Operations: Sunil Kumar Manager Production: N. C. Pant Cover Designer: Raman Kumar
Typeset by County Caramels Printed and bound at Rajkamal Electric Press, Kundli, Haryana

PREFACE

It gives us immense pleasure to place before the pharmacy students our humble work on pharmaceutical organic chemistry, which has been written strictly in accordance with the syllabus prescribed by the All India Council for Technical Education (AICTE) and Pharmacy Council of India (PCI) for the students of all Indian universities. Our aim in writing this book has been to present the fundamental principles of organic chemistry for pharmacy students on modern lines. None of the pharmacy books available in the market covers the revised syllabus entirely. Keeping in view the requirements of the students and the teachers, this book has been written to cover all the topics within the desired limits of the prescribed syllabus. It is hoped that the book will meet the requirements of the organic chemistry students at large.
Based on the vast teaching experience of the authors, the text has been prepared in a simple, lucid and comprehensive style. The manuscript has been presented as if the teacher is talking to the students in the class­room. Throughout the text special care has been taken to add Memory Focus boxes at relevant stages to help the
students revise the subject matter quickly. Textboxes with special information/knowledge titled as Remember, Learning Plus and Noteworthy Points have been added to highlight the important points.
Here is a book that resolves all the queries and doubts of organic chemistry students. It provides them the fundamentals of pharmaceutical organic chemistry, which are required by them as a pharmacist. The book will not only help them to score better in the examination but also develop their skills to apply their knowledge of pharmaceutical organic chemistry in solving the problems that they may face during their pharmaceutical career.
We express sincere thanks to the authors and publishers whose works have been consulted in producing this book. Acknowledgements are also due to the editorial team of Elsevier for their sustained interest during the publication of this book.
Although care has been taken while preparing and processing the manuscript, yet errors and misprints might have crept in. We shall be grateful to the students and teachers who would be kind enough to send their suggestions for further improvement of the book.
We shall consider our efforts amply rewarded if all those for whom the book is intended are beneted by it.
–Authors
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Dedicated
to all those who
toiled in shaping me
into what
I am today
– S. K. Bhasin
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