Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:

Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_2572_Библиотеки_им_академика_М_И_Перельмана

.pdf
Скачиваний:
0
Добавлен:
29.08.2026
Размер:
83 Мб
Скачать
244 THE REPRODUCTIVE SYSTEM
https://t.me/med1917
ABC
Fig. 11.10 Clinical examination of the breast. Examine each quadrant of the breast systematically, from the outside towards the nipple, including under the nipple.
Palpate the regional lymph nodes. The axilla and supra-
clavicular fossa are best examined with the patient in a sitting position.
Support the full weight of the patient’s arm at the wrist
with your ipsilateral arm, place your contralateral hand high into the axilla and move it upwards over the chest to the apex. Compress the contents of the axilla against the chest wall. Dene the characteristics of any mass (see
Box 3.8 in the 14th edition).
Palpate the neck for the supraclavicular lymph nodes from
behind (see Chapter 9).
Fig. 11.11 Malignancy in the upper outer quadrant of left breast: painless,
solid, irregular mass, xed to the overlying skin.
11.2 Summary of examination ndings in commonly presented breast conditions
Commonly
Conditions Examination ndings
Fibroadenoma
Breast cyst
Lactational mastitis
Non­lactational mastitis
Malignancy
Extremely mobile, discrete,
rubbery lump
Solitary or multiples in one or
both breasts
Firm, discrete, smooth lump
Solitary or in clusters
Pain, localised erythema and
swollen breast
Usually a history of cracked nipple
Peri-areolar infection: peri-areolar
erythema and a mass or abscess
Peri-areolar stula
Painless, solid, irregular mass,
which can be xed to surrounding tissues, leading to other skin and nipple changes (see Fig. 11.11)
affect
Young
women <35 years
Perimeno-
pausal women
Breastfeeding
women
Young female
smokers
Women
>50 years
Investigations
Any breast abnormality, especially a breast lump, should be assessed by triple assessment: a combination of clinical, radio­logical and pathological examination.
Radiological examination options include mammography (Fig. 11.12) and ultrasonography (Fig. 11.13). Digital breast tomosynthesis (Fig.11.14) is sometimes used as an adjunct to standard mammography. Mammography is offered to women aged 40 or over, often in conjunction with ultrasonography, to detect malignancy. For women under 40, ultrasound is often the only imaging required. High breast density in younger women decreases the sensitivity of mammography for the detection of cancer. However, if there is a strong clinical and ultrasonographic suspicion of malignancy, then mammography is performed. Digital breast tomosynthesis increases cancer detection by increasing visibility between overlapped dense breast tissue. Breast MRI is the most sensitive technique for the detection of breast cancer; in selected cases, it can be used to evaluate the extent of cancer and for screening. It is also useful in assessing breast implant integrity.
The pathological examination involves a biopsy (Box 11.3). Image-guided biopsy improves diagnostic accuracy.
Anatomy and physiology • 245
https://t.me/med1917
X-ray
tube
Fig. 11.12 Digital mammogram. A spiculate opacity characteristic of a
cancer (arrow).
Fig. 11.13 Ultrasound of a breast cyst. A characteristic smooth-walled,
hypoechoic lesion (arrow).
Digital detector
Fig. 11.14 Digital breast tomosynthesis. The x-ray tube moves along an
acquisition angle obtaining projectional images (slices) of the compressed breast. These stacked images are then reconstructed to create three­dimensional images of the breast.
11.3 Fine-needle aspiration vs core biopsy
Fine-needle aspiration Core biopsy
Material examined
Indications Aspiration of cysts
Advantages and disadvantages
Cells Tissue
Lymph node assessment Sampling an area where core biopsy is technically not possible
Unable to distinguish between non-invasive and invasive cancer Molecular markers difcult to obtain
Breast lump assessment Lymph node assessment
Can differentiate between non-invasive and invasive cancer Enables tumour grade and molecular markers assessment
11
FEMALE REPRODUCTIVE SYSTEM
Anatomy and physiology
The female reproductive organs are situated within the bony pelvis (Fig. 11.15). They cannot normally be felt on abdominal palpation. A vaginal examination is required for their routine assessment.
The vulva (Fig. 11.16) consists of fat pads, called labia majora, covered with hair. The labia minora are hairless skin aps at each side of the vulval vestibule, which contains the urethral opening
and the vaginal orice. The clitoris is situated anteriorly where the labia minora meet and is usually obscured by the prepuce. Pos­teriorly the labia meet at the fourchette, and the perineum is the bromuscular region posteriorly that separates it from the anus.
The vagina is a rugged tube 10–15 cm in length. There is an irregular mucosal ring two centimetres into the vagina that rep­resents the remnants of the hymen (see Fig. 11.16). Bulging into the top of the vagina is the grape-sized brous uterine cervix,
r
246 THE REPRODUCTIVE SYSTEM
https://t.me/med1917
Ovary
Uterus
Bladder
Fig. 11.15 Pelvis and pelvic organs.
Mons pubis
Frenulum of clitoris
Labium majus
Labium minus
Clitoris
Vestibule
Vestibule
Fourchette
Sacrum
Iliac crest
Fallopian tube
Symphysis pubis
Posterior fornix
Anterior fornix
Lateral fornix
Rectum
Cervix pouts into apex of vagina
Bladde
Vagina
Fig. 11.18 Sagittal and coronal sections of the uterus. The vaginal
fornices are shown.
Pubic hair
Prepuce
External urethral orifice (meatus)
Vaginal orifice
Hymen
Posterior commissure
Anus
Fig. 11.16 External female genitalia.
Suspensory ligament of ovary
cavity
Uterine body
Cervical canal
Vagina
Fig. 11.17 Section through the pear-shaped, muscular uterus. The
cervix, uterine body (corpus), fundus and Fallopian tubes, with the ligamentous attachments of the ovary. The uterine mucosa is the endometrium. The cervical canal has an internal and an external os.
with the external cervical os on its surface (Fig. 11.17). The fornices are the areas of the top of the vagina next to the cervix (Fig. 11.18).
Perineum
FundusUterine
Internal os External cervical os
Fallopian tube
Ampulla
Ovarian ligament
Endometrium
Myometrium
Broad ligament
The uterus is a muscular pear-shaped structure, about the size of a large plum, situated in the midline and usually tilted anteriorly over the bladder (Fig. 11.19). Its internal cavity is lined by endometrium that proliferates, secretes and breaks down during the menstrual cycle. The Fallopian tubes run laterally from the uterine fundus towards the ovaries (see Fig. 11.17). Their distal nger-like mbriae collect the oocyte after ovulation.
The ovaries are about the size of a walnut and sit behind and above the uterus close to the pelvic sidewall. At mid-cycle, one ovary will have developed a uid-lled preovulatory follicle measuring around 2 cm in diameter. The female reproductive tract is in close proximity to the bladder, ureter and lower gastrointestinal tract (see Fig. 11.19).
The history
Identify the patients main symptoms, how these developed, their day-to-day impact, how they cope and their ideas, con­cerns and expectations of the encounter. Document any pre­vious investigations and management. Check the history, even if an asymptomatic patient has come for a routine cervical smear.
Sacral
https://t.me/med1917
promontory
The history 247
Fig. 11.19 Lateral view of the female internal genitalia. The relationship to the rectum and bladder.
Take a gynaecological history by asking about:
(in pre- or perimenopausal patients) last menstrual period (LMP) and whether it was normal; always consider that these patients might be pregnant
past and present contraceptive use
plans for fertility
previous cervical smears, when taken, and any treatment
required for abnormalities
prior abdominal surgery, pelvic infection or sexually trans­mitted disease
prior pregnancies and their outcomes
current or previous hormone replacement therapy
other medication with potential gynaecological effects (see later).
Common presenting symptom s
Abnormal vaginal bleeding
If patients present with heavy periods, ask about:
flooding: whether menstrual blood soaks through protection, increased requirements for sanitary protection
passing of blood clots.
Menstruation normally occurs monthly from the menarche (average age 12) until the menopause (average age 51). Menstrual bleeding for 3–6 days normally occurs every 22–35 days (average
28). A menstrual cycle with bleeding for 4–5daysevery25–29 days is recorded as 4–5/25–29. Heavy menstrual bleeding (HMB, pre­viously called menorrhagia) affects 20% of menstruating patients over 35 and is dened as >80 mL blood loss during a period (average 35 mL). As this is not quantied in routine practice, HMB is subjective. Anaemia implies heavy bleeding.
Unexpected bleeding suggests endometrial or cervical pa­thology. Ask when the bleeding occurs:
between periods (intermenstrual bleeding, IMB)
after intercourse (postcoital, PCB)
Sacro uterine
ligament
Pouch of Douglas
Cervix
Fornix of vagina
Levator ani muscle
External
anal sphincter
Anus
Ureter
Fallopian tube
Ovarian ligament
Fundus of uterus Body of uterus Bladder Vagina Symphysis pubis
Urethra
Clitoris
Labium minus
Labium majus
more than 1 year after menopause (postmenopausal bleeding, PMB).
Approximately 4% of postmenopausal patients experience bleeding, which must be investigated as 10% have endometrial cancer.
Lack of periods (amenorrhoea) in the absence of pregnancy implies ovarian dysfunction and affects 5–7% of females in their reproductive years. Distinguish between:
Primary amenorrhoea: periods have not started by age 16.
Both ovarian function and the structure of the reproductive tract should be investigated.
Secondary amenorrhoea: there have been no periods
for 6 months, but there was previous menstruation.
Oligomenorrhoea: the menstrual cycle is longer than 35 days.
Thirty percent of patients experience vaginal bleeding in early pregnancy. Establish if this is associated with lower abdominal pain. Although the pregnancy may continue normally, bleeding is associated with miscarriage and ectopic pregnancy. Further investigation is required, particularly if the bleeding is associated with lower abdominal pain.
Lower abdominal pain
Lower abdominal pain may arise from the reproductive organs or the urinary or gastrointestinal tract or be musculoskeletal or neurological in origin (p. 108). Psychological and social factors may also contribute to the experience of pain.
To differentiate between the possible causes of lower abdominal pain, ask about:
site of the pain (unilateral, bilateral or midline)
onset (sudden or gradual, cyclical/related to menstruation or
not).
Ovarian pain is often unilateral and can be physiological (Mit- telschmertz is discomfort associated with ovulation). Ovarian cyst accidents involving torsion (twisting on the vascular pedicle
11
248 THE REPRODUCTIVE SYSTEM
https://t.me/med1917
causing acute ischaemia), haemorrhage or rupture can lead to acute severe pain.
Primary dysmenorrhoea is pain arising from intense uterine contractions just before and during peak menstruation. Sec­ondary or progressive dysmenorrhoea, due to underlying pa­thology such as endometriosis or chronic infection, often manifests as pain that lasts beyond the normal menstrual cycle. Infection, pelvic adhesions and endometriosis can cause generalised pain (Box 11.4).
Dyspareunia is pain during intercourse. Ask if it is felt around the vaginal entrance (supercial) or within the pelvis (deep). Pain due to an involuntary spasm of muscles at the vaginal entrance (vaginismus) may make intercourse impossible. Persistent deep dyspareunia suggests underlying pelvic pathology. Dyspareunia can be due to vaginal dryness following menopause.
Iliac fossa pain in early pregnancy is commonly associated with a corpus luteum cyst of the ovary but may indicate a tubal ectopic pregnancy. Ruptured ectopic pregnancy results in generalised abdominal pain, peritonism, haemodynamic insta­bility and referred pain in the shoulder.
Abdominal distension and bloating
Pelvic masses can cause non-specic symptoms like abdominal distension, bloating or urinary frequency due to pressure on the bladder. They may also be asymptomatic and picked up during routine abdominal or vaginal examination. Uterine masses include pregnancy and benign leiomyoma tumours (broids). Large ovarian cysts can also be midline, and malignant ovarian cysts are associated with ascites.
Vaginal discharge
Discharge may be normal and variable during the menstrual cycle. Prior to ovulation, it is clear, abundant and stretches like egg white; after ovulation, it is thicker, does not stretch and is
less abundant. Abnormal vaginal discharge occurs with infection. Ask about:
consistency
colour
odour
associated itch, pain or dysuria.
The most common non-sexually transmitted infection (caused by Candida species) gives a thick, white, curdy discharge often associated with marked vulval itching. Bacterial vaginosis is a common, non-sexually acquired infection caused by multiple bacteria, particularly Gardnerella vaginalis, producing a watery, shy-smelling discharge. The pH of normal vaginal secretions is usually <4.5, but in bacterial vaginosis, it is >5. Sexually trans­mitted infections (STIs) can cause discharge, vulval ulceration or pain, dysuria, lower abdominal pain and general malaise. They may also be asymptomatic.
Urinary incontinence
Inappropriate and involuntary voiding of urine is severe in 10% of cases, and its prevalence increases with age.
Stress incontinence occurs on exertion, coughing, laughing or sneezing and is associated with pelvic oor weakness.
Urge incontinence is an overwhelming desire to urinate when the bladder is not full due to detrusor muscle dysfunction.
Prolapse
In 30% of patients, the pelvic contents bulge into the vagina (Fig. 11.20). They feel something coming down, particularly when standing or straining. Uterine prolapse is associated with previous childbirth and is classied as:
Grade 1: halfway to the hymen.
Grade 2: at the hymen.
Grade 3: beyond the hymen.
Grade 4 (procidentia): external to the vagina (Fig. 11.21).
11.4 Characteristics of pelvic pain
Site Midline Left or right iliac fossa Generalised lower abdomen; more on one
Onset Builds up before period Sudden, intermittent Builds up, acute on chronic Builds up, sudden
Character Cramping Gripping Shooting, gripping Shooting, cramping
Radiation Lower back and upper
Associated symptoms
Timing With menstruation May be cyclical Acute, may be cyclical Builds up during
Exacerbating factors
Severity Variable in spasms Intense Intense in waves Variable
Uterine pain Ovarian pain Adhesions or pelvic infection Endometriosis
side
thighs
Bleeding from vagina Known cyst, pregnancy, irregular
Positional Movement, examination Intercourse, cyclical
Groin; if free uid, to shoulder ––
Discharge, fever, past surgery Infertility
cycle
Variable
period
The physical examination 249
https://t.me/med1917
11.5 Taking a sexual history
Fig. 11.20 Anterior vaginal wall prolapse.
Cystocoele
Are you currently in a sexual relationship?
How long have you been with your partner?
Have you had any (other) sexual partners in the last 12 months?
How many were male? How many were female?
When did you last have sex with:
Your partner?
Anyone else?
Do you use barrier contraception–sometimes, always or never?
Have you ever had a sexually transmitted infection?
Are you concerned about any sexual issues?
example, obesity is associated with an increased risk of gynae­cological malignancy.
11
Sexual history
Sometimes a sexual history is required, but people often nd it difcult to talk about sexual matters. It is important for you to be at ease and ask questions in a straightforward manner. Explain why you need to enquire, use clear, unambiguous questions (Box 11.5) and be non-judgemental. The sexual partners of pa­tients with STIs should be informed and treated to prevent further transmission and reinfection of the treated person. Condentiality is paramount, so do not give information to a third party. Do not perform a pelvic examination on someone who has not been sexually active.
Fig. 11.21 External prolapse of the uterus.
The top of the vagina (vault) can also prolapse after a previous hysterectomy. More commonly, the bulge relates to the vaginal wall. A cystocoele is a bulge on the anterior wall containing the bladder (see Fig. 11.20), and a rectocoele is a bulge on the posterior wall containing the rectum. An enterocoele is a bulge of the distal wall posteriorly containing the small bowel and peritoneum.
Drug history
Tamoxifen has oestrogenic effects in postmenopausal patients, antibiotics can cause vaginal candidiasis, antipsychotic drugs can cause hyperprolactinaemia, and antiepileptic or antituberculous drugs may reduce the effectiveness of oral contraceptives.
Family and social history
Family and social history, including smoking status and lifestyle, may also have an impact on gynaecological conditions. For
The physical examination
A vaginal examination is required to perform a routine cervical smear. Otherwise, the focus of gynaecological examination is to detect abnormalities that could explain the symptoms or alter treatment options (e.g. body mass index (BMI) and blood pres­sure assessment affect the use of the contraceptive pill). Signs of gynaecological disease are not limited to the pelvis, and a gen­eral, as well as a pelvic, examination is required (Box 11.6). You should offer a chaperone and record this in the records. The examination area should be private, with appropriate equipment and an adjustable light source available. The patient should have an empty bladder and remove their clothing from the waist down, along with any sanitary protection. Give them privacy to do this.
Passing a speculum
Explain what you are going to do and why it is necessary, and obtain verbal consent. Use a vaginal speculum to see the cervix and the vaginal walls, carry out a cervical smear and take swabs if required. Specula are metal or plastic and come in various sizes and lengths. Metal specula may be sterilised and reused; plastic specula are always disposable. A metal speculum is cold, so
250 THE REPRODUCTIVE SYSTEM
https://t.me/med1917
11.6 Focus of the gynaecological examination
Clinical feature General examination Pelvic examination
Abnormal bleeding Anaemia
Underweight (hypogonadotrophic hypogonadism) Galactorrhoea, visual eld defects (hyperprolactinaemia) Hirsutism, obesity, acanthosis nigricans (PCOS)
Pain Abdominal tenderness Uterine excitation (acute infection or peritonism)
Vaginal discharge Rash (associated with some STIs) Clear from cervix (chlamydia)
Urinary incontinence Obesity, chronic respiratory signs (stress incontinence)
Neurological signs (urge incontinence)
Abdominal distension or bloating Ascites, weight loss, lymphadenopathy, hepatomegaly (malignancy)
Pleural effusion (some malignant or benign ovarian cysts)
PCOS, Polycystic ovary syndrome; PMB, postmenopausal bleeding; STI, sexually transmitted infection.
warm it under the hot tap. Most patients nd a speculum ex­amination mildly uncomfortable, so always use a small amount of lubricating gel on the tip of each blade. Clean your hands and put on medical gloves. Ask the patient to lie on their back on the couch, covered with a modesty sheet to the waist, with their knees bent and apart (Fig. 11.22).
Enlarged uterus (broids, pregnancy) Abnormal cervix Open cervical os (miscarriage) Vaginal atrophy (most common cause of PMB)
Fixed uterus (adhesions or endometriosis) Adnexal mass (ovarian cyst)
Purulent from cervix (gonorrhoea) Frothy with strawberry cervix (trichomoniasis)
Demonstrable stress incontinence Uterine or vaginal wall prolapse
Pelvic mass (uterine, ovarian or indiscriminate) Fixed uterus and adnexae Abnormal vulva (skin disease or malignancy)
Examination sequence (Videos 22 and 22A)
Look at the perineum for any deciency associated with
childbirth; note abnormal hair distribution and clitoromegaly (associated with hyperandrogenism). Note any skin abnor­malities, discharge or swellings of the vulva, such as the Bartholins glands on each side of the fourchette (Fig. 11.23).
Ask the patient to cough while you look for any prolapse or
incontinence.
Gently part the labia using your left hand (Fig. 11.24). With
your right hand, gently insert a lightly lubricated bivalve speculum (Figs 11.25–11.26A), with the blades vertical, fully into the vagina, rotating the speculum through 90 degrees so that the handles point anteriorly and the blades are now horizontal (see Fig. 11.26B). Someone who has been preg­nant may need a larger or longer speculum or a bolster under the sacrum if the cervix is very posterior. If they nd the ex­amination difcult, ask them to try to insert the speculum themself.
Slowly open the blades and see the cervix between them. If
you cannot see it, reinsert the speculum at a more downward angle, as the cervix may be behind the posterior blade. Note any discharge or vaginal or cervical abnormalities.
Open the blades a little during the initial removal of the
speculum to avoid catching and pulling on the cervix.
Fig. 11.22 Position for pelvic examination.
To assess prolapse (Video 22B)
Ask the patient to lie on their left side and bring their knees up
to their chest.
Use a univalve Sims speculum, placing a small amount of
lubricating jelly on the blade.
The physical examination • 251
https://t.me/med1917
Fig. 11.23 Bartholins abscess.
Fig. 11.24 Inspection of the vulva.
A
11
B
Fig. 11.26 Bivalve speculum examination. A Insertion of the speculum.
B Visualisation of the cervix after rotation through 90 degrees.
Fig. 11.25 Bivalve speculum.
Insert the blade to hold back the posterior wall.
Ask them to cough while you look for uterine descent and the
bulge of a cystocoele (Fig. 11.27).
Repeat, using the speculum to hold back the anterior vaginal
wall to see a rectocoele or enterocoele.
Taking a cervical smear
There are two ways of taking a smear:
using liquid-based cytology
using a microscope slide.
252 THE REPRODUCTIVE SYSTEM
https://t.me/med1917
Fig. 11.27 Examination in the left lateral position using a Sims
speculum.
Liquid-based cytology is increasingly common, as it allows for efcient processing and gives fewer inadequate smears. Many screening services now test these for human papilloma virus (HPV) rather than performing routine cytology.
Examination sequence (Video 22C)
Always label the cytological medium or slide and ask the
questions required to ll in the request form before starting the examination to avoid mixing specimens.
Clearly visualise the entire cervix.
Liquid-based cytology
Insert the centre of the plastic broom into the cervical os.
Rotate the broom 5 times through 360 degrees (Fig. 11.28A).
Push the broom 10 times against the bottom of the specimen
container.
Twirl 5 times through 360 degrees to dislodge the sample.
Firmly close the lid.
Conventional smear
Insert the longer blade of the spatula into the cervical os.
Rotate the spatula through 360 degrees (see Fig. 11.28B).
Spread once across the glass slide.
Place the slide immediately into xative (methylated spirits) for
34 minutes.
Remove it and leave it to dry in the air.
Cytology
specimen jar
A
Name
Date of birth
B
Glass slide
Fig. 11.28 Taking a cervical smear. A Liquid-based cytology. B Using
a spatula.
Bimanual examination
Examination sequence (Video 22D)
Apply gloves and lubricate your right index and middle nger
with gel.
Gently insert them into the vagina and feel for the rm cervix.
The uterus is usually anteverted (Fig. 11.29A), and you can feel its rmness anterior to the cervix. If the uterus is retro­verted and lying over the bowel (15%; Fig. 11.29B), you will feel the rmness posterior to the cervix.
Push your ngers into the posterior fornix and lift the uterus
while pushing on the abdomen with your left hand.
Place your left hand above the umbilicus and bring it down,
palpating the uterus between both hands and note its size, regularity and any discomfort (Fig. 11.30).
AB
Fig. 11.29 Coronal section. A Anteverted uterus. B Retroverted uterus.
Fig. 11.30 Bimanual examination of the uterus. Use your vaginal ngers
https://t.me/med1917
to push the cervix back and upwards, and feel the fundus with your abdominal hand.
Investigations 253
11
Fig. 11.31 Palpating an adnexal mass.
Move your vaginal ngers into the anterior fornix and palpate
the anterior surface of the uterus, holding it in position with your abdominal hand.
Move your ngers to the lateral fornix and, with your left hand
above and lateral to the umbilicus, bring it down to assess any adnexal masses between your hands on each side (Fig. 11.31).
If urinary leakage occurs when the patient coughs, try lifting
the anterior vaginal wall with your ngers and ask them to cough again. This stops genuine stress incontinence.
The normal cervix os may be a slit after childbirth. The vaginal squamous epit helium and the endocervic al columnar epithelium meet on the cervix. The position of this squamo­columnar junction varies considerably, so the ce rvix can look very different in individual p eople. If the transition zone is on the cervix, this is called an ectopy and looks red and friable; there may be small cysts called Nabot hian foll icles. The normal uterus should feel regular and be mobile and the size of a plum. The Fallopian tubes cannot be felt, and normal ovaries are palpable only in the very slim.
Vulval changes include specic skin diseases, infections such as herpes or thrush, and malignancy. Visual abnormalities of the cervix such as ulceration or bleeding suggest cervical pathology, including polyps or malignancy. Tender nodules in the posterior fornix suggest endometriosis, and both endometriosis and pelvic adhesions cause xation of the uterus. Acute pain when touching
the cervix (cervical excitation) suggests an acute pelvic condition such as infection, cyst accident or tubal rupture.
Fibroids can cause uterine irregularity and enlargement. The size is related to that of the uterus in pregnancy. A tangerine­sized uterus is 6 weeks, an apple at 8 weeks, an orange at 10 weeks and a grapefruit at 12 weeks. After 12 weeks, the uterus can be palpated suprapubically on abdominal palpation. A large midline mass may be ovarian or uterine. Push the mass upwards with your left hand and feel the cervix with your right hand; if the mass moves without the cervix, this suggests it is ovarian.
Investigations
Common gynaecological investigations are summarised in
Box 11.7. Patients of reproductive age should be considered
potentially pregnant, and a pregnancy test is routine. The mainstay of gynaecological investigation is a pelvic ultrasound scan, which can be carried out abdominally or transvaginally (Fig. 11.32). Endometrial biopsy is a common test, particularly for PMB, and is performed during vaginal examination using a suction catheter (Pipelle, Fig. 11.33). When a couple presents with subfertility, the key female investigations are serum pro­gesterone 1 week before expected menses to conrm ovulation and a test of tubal patency (Fig. 11.34).