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Shared Decision-making 33
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Box 5.7 An example of a Patient Decision Aid (PDA)
Reproduced with permission from the British Menopause Society: https://thebms.org.uk/publications/tools-for-clinicians (accessed July
2022).
Box 5.8 Mental checklist for use when considering the use of
decision aids
• Is there a decision tool that is helpful here?
• Have I checked that this is the correct tool to use with my patient?
• Have I gathered all the information that I need from the patient?
• What is this individual patient’s context?
• What are this individual patient’s beliefs, values, and preferences?
• Can I explain this clearly to this individual patient, mindful of their health literacy?
This emphasises the importance of directly consulting with patients in the development of clinical reasoning, and some of those patient encounters at an appropriate stage in learner development should be unfiltered (e.g., in primary care or hospital assessment areas) to maximise the learning potential of the encounter.
Box 5.8 shows a mental checklist for clinicians to use when considering the use of decision aids for a specific consultation with an individual patient.
Summary
Clinical decision-making can be supported by using a variety of clinical guidelines, scores, and decision aids. These can help with diagnostic and management decisions. However, the clinician must ensure that the correct decision aid is used and it must be interpreted within the context of a comprehensive clinical assessment, in which good communication skills are crucial to undertaking a purposeful history and physical examination. After a diagnosis is made, clinical decision-making continues and should be shared between the clini­cian and patient whenever possible. During shared decision-making, evidence-based medicine requires the clinician’s expertise to apply scientific knowledge appropriately to the patient’s unique circum­stances, and communicate in a way that is easily understood, being mindful of each individual patient’s health literacy.
Acknowledgement
A proportion of this chapter is based on the original chapter written for the first edition of the ABC of Clinical Reasoning. The authors therefore wish to acknowledge the contribution of Professor Maggie Bartlett (Professor Emeritus, Dundee University) to this chapter through her co-authorship of the original chapter.
References
1. Shekelle PG, Woolf SH, Eccles M and Grimshaw J. (1999). Developing guidelines. BMJ; 318: 593–596 (part of a four article series on the development and use of clinical guidelines).
2. Wells PS, Anderson DR, Bormanis J et al. (1997). Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet; 350(9094): 1795–1798.
3. The Rome Foundation. Rome IV Criteria. https://theromefoundation.org/ rome-iv/rome-iv-criteria. (Accessed July, 2022).
Lim WS, van der Eerden MM, Laing R et al. (2003). Defining community
4. acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax; 58: 377–382.
5. Mayfield D, McCleod G and Hall P. (1974). The CAGE questionnaire: vali­dation of a new alcoholism screening questionnaire. American Journal of Psychiatry; 131: 1121–1123.
6. Sackett DL, Strauss SE and Richardson WS. Evidence-based medicine: how to practice and teach EBM. London: Churchill-Livingstone, 2000.
7. Cobb P. Situated cognition: contemporary developments. In: Smelser NJ and Baltes PB (Eds). International encyclopedia of the social & behavioral sciences. Pergamon, 2001. pp 14121–14126.
8. Durning SJ, Artino AR Jr, Pangaro LN, van der Vleuten C and Schuwirth L. (2010). Perspective: redefining context in the clinical encounter: implica­tions for research and training in medical education. Academic Medicine; 85(5): 894–901.
9. Brown JS, Collins A and Duguid P. (1989). Situated cognition and the culture of learning. Educational Researcher; 18(1): 32–42.
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CHAPTER 6
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Models of Clinical Reasoning
Nicola Cooper
OVERVIEW
• Models of clinical reasoning can be useful for clinicians, teachers, and learners
Clinical reasoning can be viewed from different perspectives
• Critical thinking is not the same as clinical reasoning
• A dual process model is a widely accepted framework with which to understand diagnostic reasoning and diagnostic error
• There is good evidence that rational decision-making often requires a third process – termed reflective processing or metacognition
• Expertise in clinical reasoning requires knowledge and experience, but also motivation, effort, and metacognitive skills
Introduction
Models of clinical reasoning can be useful to help us understand the processes underpinning our decision-making, as clinicians, teachers, and learners. The problem is that clinical reasoning research has its origins in the medical education, cognitive psy­chology, diagnostic error, and health systems literature. This frag­mented literature makes it difficult for clinicians and educators to access and adopt meaningfully into their practice. This chapter therefore aims to summarise some of the literature related to models of clinical reasoning.
Different Perspectives
Clinical reasoning can be viewed from different perspectives (see Figure 6.1). One perspective is that clinical reasoning is to do with knowledge, how knowledge is organised in long-term memory as mental representations, and the cognitive processes responsible for storing, transforming, and retrieving these. It is also about how clinicians use analytic and non-analytic strategies inter­changeably when facing a diagnostic problem [1]. This view of clinical reasoning is informed by decades of research in the cognitive sciences and by dual process theorists.
Another perspective is that clinical reasoning is something that is ‘situated’ in the environment. Here, clinical reasoning is inter­dependent with various external factors such as the patient, information technology (IT) systems, physical space, time con­straints, and so on. This view of clinical reasoning is informed by the situativity theories [2]. Accordingly, knowledge is not something that exists solely inside a person’s organised cognitive structures, but is entangled in the activity of providing care for the patient [1].
Yet another perspective is that good clinicians need to be able to go beyond the ‘content’ and make sense of the patient’s illness (and their own response to it), to understand the practice of med­icine in its wider socio-cultural context, and to ask: ‘What is going on with this particular patient?’ This involves much more than the application of knowledge or evidence-based guidelines. It involves the ability to tolerate uncertainty and craft a deliberate course of action appropriate for the circumstances – what we might call wisdom [1]. This view of clinical reasoning is informed by sociology, anthropology, and the humanities, including narra­tive medicine (see further resources).
All these perspectives are valid and valuable. As we stated in Chapter 1, these perspectives are not mutually exclusive. However, the focus for teachers and learners is very much on knowledge and knowledge organisation, at least to begin with. As learners progress, they can begin to understand clinical reasoning as something that is situated in the environment where they can make use of all the affordances available to them. Hopefully, with time, they will learn to navigate beyond the content to become wise clinicians.
Critical Thinking Vs Clinical Reasoning
Before we discuss a widely accepted model of clinical reasoning, it is important to correct a common misunderstanding. ‘Critical thinking’ is a term sometimes used interchangeably with clinical reasoning, but they are not the same thing. Critical thinking is an important component of reasoning in general. A definition of critical thinking can be found in Box 6.1. But clinical reasoning
ABC of Clinical Reasoning, Second Edition. Edited by Nicola Cooper and John Frain. © 2023 John Wiley & Sons Ltd. Published 2023 by John Wiley & Sons Ltd.
36 ABC of Clinical Reasoning
recognised
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It’s like a huge fan …
It’s like a snake!
Figure 6.1 Clinical reasoning and different perspectives. A group of blind men heard that a strange animal had been brought to town so they went to investigate. They gathered round and felt the animal carefully, each person stating what they thought it was like. The parable of blind men and an elephant is found in Buddhist, Hindu, and Jain texts, as they discuss the limits of perception and the importance of context. The parable has several variations.
Box 6.1 A definition of critical thinking
‘The intellectually disciplined process of actively and skilfully conceptualising, applying, analysing, synthesising, or evaluating information gathered from, or generated by, observation, experi­ence, reflection, reasoning, or communication, as a guide to belief and action. In its exemplary form, it is based on universal intellectual values that transcend subject matter divisions: clarity, accuracy, precision, consistency, relevance, sound evidence, good reasons, depth, breadth, and fairness.’
From the US National Council for Excellence in Critical Thinking https://www.criticalthinking.org/pages/defining-critical-thinking/766 (accessed April 2022).
It’s like a thick wall
It’s like a rope …
It’s like a tree trunk
involves being able to gather data and interpret it. It involves the senses: vision, touch, hearing, and smell. It requires specific clinical knowledge, skills, and behaviours.
Critical thinking has its roots in the teaching of Socrates and is related to logic. Logic is to do with the analysis of arguments – more specifically the study of arguments which are made up of a set of premises together with a conclusion. Three types of logical reasoning are deduction, induction, and abduction (see further resources). However, good thinking cannot be reduced to logical thinking. Rationality is the term used by psychologists to describe good thinking – thinking that is ‘reasonable, based on facts or reason’ [3]. It not only encompasses logical methods of problem­solving but also incorporates our beliefs, values, goals, and context.
There are several different models of rationality [4]. The two most relevant to medicine are epistemic (or evidential) rationality – what is true – and instrumental rationality – what to do. Epistemic rationality is to do with how well our beliefs are commensurate with the available evidence. Instrumental rationality is to do with adopting suitable means to an end given the resources available to us. Thus, rationality in medicine is not about every decision being ‘correct’ or error free. On the contrary, rational decision‐ making takes into account the consequences of possible errors to aid in arriving at desirable outcomes [4]. A person’s capacity for
Knowledge
Critical
thinking
ability
Cognitive
ability
Figure 6.2 Components of rationality. *Individual characteristics include things like cognitive style, personality, gender, age, and other variables. Adapted from Croskerry, 2017.
Individual
characteristics*
rational thinking is influenced by several factors, illustrated in Figure 6.2.
Dual Process Theories
In 2009, Croskerry described research on human thinking and decision-making which provides a basic framework for under­standing diagnostic reasoning [5]. Since his description of dual process theories as applied to medicine, a dual process model has become widely accepted as a framework with which to under­stand diagnostic reasoning and diagnostic error (see Figure 6.3). However, this model is often misunderstood, so this next section aims to describe dual process theories as applied to medicine and then clarify some common misunderstandings.
Humans have two distinct processes when it comes to thinking and decision-making – one that is intuitive and subconscious and one that is analytical and conscious. This ‘dual process’ is sup­ported by many experiments in psychology as well as functional magnetic resonance imaging [6, 7]. These two processes are called Type 1 and Type 2 respectively and their characteristics are listed in Box 6.2.
Type 1 processing is intuitive and subconscious, a result of sev­eral systems in the brain that operate autonomously and in parallel in response to their own stimuli. They are a result of:
Processes that are hard-wired/evolutionary (e.g., represen­tativeness)
’Recognised‘
Clinical
presentation
Not
Figure 6.3 A simplified model of diagnostic reasoning. Adapted from Croskerry, 2009.
Type 1
processing
Overlearning
and practice
Type 2
processing
Override
Calibration Diagnosis
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Box 6.2 Characteristics of Type 1 and Type 2 processes
Type 1 Type 2
Intuitive, uses heuristics (mental shortcuts/pattern recognition)
Automatic, pre- or subconscious
Low effort
Non-language based
High processing capacity
Highly contextualised
Processes that are regulated by emotions (e.g., fear of snakes
Analytical, systematic
Deliberate, conscious
High effort
Language based
Limited capacity
Decontextualised
which is evolutionary, or dislike of certain people groups, which is learned)
Processes embedded through overlearning (e.g., driving)
Processes embedded through implicit learning (e.g., stereotyping) Type 2 processing, on the other hand, is analytical and conscious and serial in nature. It is often language based and uses rules. Its most distinctive characteristic is hypothetical thinking and its ability to override early Type 1 responses and substitute better ones via a process of cognitive stimulation.
When you instantly recognise something because you have seen it before, you have engaged in Type 1 processing. When you have to go through a deliberate process in order to figure out what something is, you have engaged in Type 2 processing. When you think you recognise something, but then pause and say to yourself, ‘Hang on a minute, what else could this be?’ you have over-ridden your early Type 1 response and engaged in cognitive simulation.
Different dual process theories make different assumptions about the relationship between Type 1 and Type 2 processing, with some assuming the two occur in parallel, others assuming that processing is sequential, and others assuming that one or the other is used in a given situation. Most dual process theories assume that Type 1 processing makes use of associations that are built up through repeated experience, while Type 2 processing can use information that has been learned only on a single occasion.
In clinical practice, Type 1 processing accesses schemas, or pat­terns, based on formal and experiential learning, known as ‘illness scripts’. According to script theory, medical knowledge is bundled into networks that allow clinicians to integrate new information with existing knowledge, recognise patterns and irregularities in clinical presentations, identify similarities and differences bet­ween diseases, and make predictions about how diseases are likely to unfold [7]. These knowledge networks become updated and refined through further experience and learning. Type 2 processing, on the other hand, uses knowledge of rules, proce­dures, and linguistically coded strategies which are used to think through problems or simulate alternatives. The knowledge, rules, procedures, and strategies utilised by Type 2 processing have been collectively termed ‘mindware’ and includes things like scientific thinking, probabilistic reasoning (see Chapter 3), and logic.
We spend most of our lives using Type 1 processing in order to conserve cognitive energy – we simply could not live our lives if
every single decision were conscious, deliberate, and effortful. We instantly recognise a chair and understand its purpose without thinking about it. After a while, clinical practice is no different, but this does not mean we cannot pause to reflect on our thinking and decision-making in the moment. In fact, engaging in reflec­tion during diagnostic decision-making has been found to be the most consistent and precise cognitive intervention for improving diagnostic accuracy. The benefit of reflection is greatest when the case is complex relative to the decision-maker [8]. Reflection can be as simple as asking oneself, ‘What’s the evidence for this? What else could it be?’ or listing findings that are compatible or not compatible with each differential diagnosis, a strategy that can be used in teaching clinical reasoning (see Chapter 10). However, people vary in their tendency to spontaneously engage in reflec­tion during decision-making – more of that later.
Common Misunderstandings
It is a common misunderstanding that errors in clinical reasoning mainly arise because of ‘cognitive biases’ (heuristics gone wrong) – a result of Type 1 processing and a failure of Type 2 processing to interrupt and override the initial intuitive response. Humans do indeed have an overwhelming tendency to default to a fast, low­effort mode of decision-making (what psychologists call being a ‘cognitive miser’) and this can certainly lead to error – an idea popularised by Kahneman in his book Thinking, Fast and Slow [9]. However, experts use Type 1 processing most of the time. For them, it is fast and highly accurate. More generally, diagnostic accuracy is associated with spending less time on a task, and get­ting clinicians to ‘slow down and be more analytical’ under exper­imental conditions does not improve accuracy. Mistakes can also occur with Type 2 processing – if the relevant mindware is not available because it has never been learned, or the relevant mind­ware is contaminated, then a suboptimal response is not the result of a failure to override Type 1 processing, but the result of a mind­ware problem – in other words, a mistake rooted in inadequate or faulty knowledge. Miserly Type 2 processing can also occur – the framing effect and search satisficing (see Chapter 7) are examples of this. Cognitive simulation takes effort, so the most easily con­structed model is likely to win, especially if the person is operating under conditions that diminish Type 2 processing, such as fatigue.
The bottom line is that no one type of processing is inherently better than the other. Both have different functions and different strengths and weaknesses and experts use multiple strategies depending on the circumstances.
Tri-Process Theory
There are few differences between individuals when it comes to a tendency to engage in Type 1 processing. But there are significant differences when it comes to a tendency to engage in Type 2 processing. Some of these differences are to do with intelligence/ cognitive ability, aspects of the environment, e.g. time pressure, and motivation or mood. But a person’s cognitive style – their tendency to seek information, look for evidence, weigh things up, have an awareness of context, and think about their own thinking – has been found to account for significant differences in performance
38 ABC of Clinical Reasoning
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on reasoning tasks after cognitive ability has been accounted for [10]. Previous dual process theories tended to ignore individual dif­ferences which are key to understanding why people of similar cognitive ability vary considerably in their performance – a phenomenon we frequently observe in clinical practice.
There is good evidence that rational decision-making often involves three processes: intuitive (Type 1) processing which may or may not generate a suboptimal response; analytical (Type 2) processing which can simulate alternatives and generate a poten­tially better response; and reflective (also Type 2) processing which initiates the override of a potentially suboptimal response in the first place [11]. These different processes all rely on differ­ent types of knowledge: intuitive processing on formal and expe­riential knowledge tightly compiled as ‘illness scripts’; analytical processing on medical knowledge, rules, procedures, and strat­egies (mindware); and reflective processing on general knowledge, beliefs, and goals. Stanovich refers to reflective processing as ‘the reflective mind’ which shares the same charac­teristics of Type 2 processing [10], while other psychologists refer to this third process as ‘metacognition’ – thinking about one’s own thinking. Rational decision-making can be seen as a function of processing at both the analytical and the reflective level (see Figure 6.4).
In clinical practice, a tri-process model is flexible depending on the circumstances. Different clinicians reflect (or not) on differ­ent aspects of any given case, depending on their own unique knowledge and experience and the situation in which they find themselves [12]. Type 2 processing is optional and effortful, and the extent to which it is engaged varies every time and individual makes a judgement, and sometimes it may not take place at all. There is no one set of cognitive, metacognitive, motivational, and behavioural strategies that constitute the desirable mode of engagement in every setting and task [13]. In clinical practice, some situations call for rapid, good enough, low-effort responses, and others for a more systematic, deliberate analysis of all the available information. The challenge for clinicians is to know when to ‘slow down when you should’ [14]. The challenge for educators is to provide clinical environments with multiple tasks and strategies in order to equip learners over time to be able to reason through a variety of clinical problems as effectively as pos­sible [12].
Errors in Thinking
Stanovich has proposed a taxonomy of thinking error types based on his tri-process model which provides a useful model for understanding diagnostic reasoning and diagnostic error, partic­ularly from an educator’s perspective [15] (see Figure 6.5). This model is entirely consistent with a number of observations in the clinical reasoning and education literature: that expertise in med­icine depends on a large and retrievable body of formal and expe­riential knowledge; that high levels of performance not only require knowledge, but also motivation and metacognitive skills; and that reasoning occurs in context, and effortful Type 2 processing is highly affected by things like distractions, fatigue, sleep deprivation, and cognitive overload – common suboptimal conditions under which clinicians operate.
In Figure 6.5, errors in thinking may occur because of a default to Type 1 autonomous processing. This is more likely to occur when the clinician is not an expert in the specific disease or pre­sentation in question. For example, representativeness is a heu­ristic (mental shortcut) humans use when estimating how likely a certain event is – they assess how similar something is compared to an existing mental prototype. These judgemental shortcuts generally get us where we need to go but sometimes they are wrong. The fact that something is more representative does not actually make it more likely [9]. For example, medical curricula, and textbooks, often present clinical problems in a prototypical fashion, but in the real world, clinical problems present with far greater variety. Most people with meningitis in countries like the USA and UK do not have neck stiffness on examination when they first present to hospital [16]. If a clinician is seeing a patient with headache, fever, nausea, and myalgia but no neck stiffness, they may dismiss meningitis as a possibility because it does not fit the prototype – even though ‘the prototype’ is in fact wrong [17].
Errors can also occur if thinking proceeds with a focal bias. Default to Type 1 autonomous processing is not always possible, particularly in novel situations, something which is more likely to be the case for inexperienced clinicians. Analytic processing may be required, but because humans have an innate tendency to be cognitive misers, the thinking that ensues may not involve a fully decoupled cognitive simulation. Search satisficing is a good example of this (see Chapter 7), when we stop searching because we have found something that fits or is convenient, instead of
’Recognised‘
Clinical
presentation
Not
recognised
Figure 6.4 Tri-process theory. Adapted from Croskerry, 2009; and Stanovich, 2011 – see references.
Type 1 processing
(intuitive)
Type 2 processing
(algorithmic)
Type 2 processing
(reflective)
Calibration Diagnosis
’Recognised‘
Clinical
presentation
Not
recognised
Figure 6.5 Taxonomy of thinking error types. Adapted from Croskerry, 2009; and Stanovich, 2011 – see references.
Type 1 processing
(intuitive)
Type 2 processing
(algorithmic)
Type 2 processing
(reflective)
Default to autonomous
processing
Serial associative
cognition with a focal
bias
Override failure
Missing mindware
Contaminated
mindware
Working diagnosis
Models of Clinical Reasoning 39
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systematically looking for the best alternative. Stanovich describes this kind of thinking as serial and analytic (as opposed to intui­tive) but relying on a single focal model (the ‘diagnosis’) that trig­gers all subsequent thought. There is no decoupling, no override, no cognitive simulation (‘What else could this be?’), and no inter­ruption of serial associative cognition.
Staying with Figure 6.5, cognitive decoupling may occur, but it may fail to suppress Type 1 processing – what Stanovich calls override failure. An example is denominator neglect when, statis­tically, x is more likely than y but, intuitively (and incorrectly) y ‘feels’ more likely. The clinician is often aware that ‘logically’ x is the correct answer, but cannot resist choosing y. This may lead to inappropriate selection of tests which in turn could lead to incidental findings or false positive results, which in turn could lead to more unnecessary investigations (see Chapter 3).
Errors can also occur with Type 2 processing when the medical knowledge, rules, procedures, and strategies (mindware) are either missing or contaminated. For example, if a clinician has never been taught the principles of choosing and interpreting diagnostic tests, a ‘positive’ or ‘negative’ result may simply be taken at face value. Or if a clinician believes (incorrectly) that normal SpO levels make it unlikely a patient has a pulmonary embolism, they may dismiss pulmonary embolism as a potential diagnosis. Rules, procedures, and strategies may also be inappropriately applied to a patient’s presentation or clinical situation (see Chapter 5).
A tri-process model of clinical reasoning can be useful for edu­cators in diagnosing difficulties and helping learners improve. A metacognitive approach to instruction (e.g., helping learners think about their own thinking by getting them to verbalise their thinking as they work) has been shown to increase learning and the degree to which students can transfer it to new settings (see Chapter 10 for details on elaboration and self-explanation). Learners can be taught to develop their own internal dialogue, increasing their ability to monitor their own thinking and under­standing [18]. However, such metacognitive skills cannot be taught in isolation from the specific content at hand.
Expertise in Clinical Reasoning
It has been shown very clearly that experience is required to develop expertise, but even extensive experience in a domain does not invariably lead to expert levels of performance [19]. After years of experience in postgraduate training, most clini­cians attain an acceptable level of proficiency to be able to do most things automatically, but if they do not engage in something called deliberate practice they simply become experienced non­experts [20]. In Ericsson’s words, most professionals reach a stable, average level of performance within a relatively short time­frame and maintain this mediocre status for the rest of their careers [19] – this level of performance is sufficient a lot of the time, but not all of the time.
Chapter 10 explains that clinical reasoning ability is highly dependent on knowledge, knowledge organisation, and delib­erate practice. It outlines what to teach and key concepts regarding
Box 6.3 Themes in the early careers of master clinicians
Theme Actions
1 Consistent
learning efforts
2 Rigorous skill
development
3 Cultivating
habits of mind
4 Working in
clinically rich environments
2
Adapted from Murthy VK, O’Brien B, Dhaliwal G. (2018). An inquiry into the early careers of master clinicians [21].
Spending time devoted to:
• Reading/studying Teaching and preparing to teach
Learning by tracking patient outcomes
Spending time purposefully refining:
• Communication/consultation skills Physical examination skills
Clinical reasoning skills
Adopting habits such as:
Having empathy towards patients
Enthusiasm for clinical medicine Humility about one’s own knowledge and
clinical abilities
• Curiosity and rigorous case analysis
Spending time:
Working in high-volume clinical areas Working outside one’s own comfort zone
Learning from peers (e.g., discussing cases) and
role models
how to teach, including curriculum design. This type of teaching and learning will hopefully lead to competence in clinical reasoning of the type required for new graduates. But what about expertise? Further insights can be gained from an inquiry into the early careers of master clinicians which found four overlapping themes: 1) consistent learning efforts, 2) rigorous skill develop ment, 3) cultivating habits of mind, and 4) working in clinically rich environments [21]. These themes are expanded further in Box 6.3.
We can also learn from other models of expertise which argue that expertise should be considered from a process perspective not an achievement perspective. What differentiates expert behaviour from non-expert behaviour? Experts have automated processes that were once cognitively effortful. As authors Moulton et al. put it, surgeons perform standard operations while talking about their tennis game, internists diagnose a patient from the end of the bed, emergency physicians immediately ini­tiate multiple tasks in a trauma victim, and family doctors recog­nise chicken pox in an instant. But when something unexpected occurs, or something does not quite fit, will the clinician in automatic mode recognise it, or will that clinician plough through, oblivious to the situation’s uniqueness and unaware of its consequences? [14] This, they say, illustrates one vital aspect of expert judgement: slowing down when you should. Considering expert judgement from this perspective allows for fluctuations in individual performances and also explains why a resident may behave in an expert manner whereas a more senior physician may not.
-
40 ABC of Clinical Reasoning
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Summary
Clinical reasoning is highly dependent on different types of knowledge, but good decision-making often requires other things: a capacity for rational thinking (see Figure 6.2), motiva­tion (including empathy), effort, metacognitive skills, and optimal ambient conditions.
While cognitive models of clinical reasoning are useful for edu­cators, developing expertise in clinical reasoning needs to go beyond this and different perspectives are important for under­standing, teaching, and learning clinical reasoning.
Developing expertise in clinical reasoning takes years, but it can be deliberately nurtured by teaching the right content, providing the breadth and depth of experience required with coaching and feedback, and explicitly letting learners know what strategies they can employ in order to become excellent clinicians.
References
1. Koufidis C, Manninen K, Nieminen J et al. (2022). Representation, inter­action and interpretation. Making sense of the context in clinical reasoning. Medical Education; 566: 98–109.
2. Durning S, Holmboe E and Graber ML (Eds). Special issue of Diagnosis. Situativity: a family of social cognitive theories for clinical reasoning and error. Open access, 2020. https://www.degruyter.com/journal/key/ dx/7/3/html?lang=en (accessed April 2022).
3.
Croskerry P. The rational diagnostician. In: Croskerry P, Cosby KS,
Graber ML, and Singh H (Eds). Diagnosis: exploring the shadows. CRC Press, 2017.
4. Djulbegovic B and Elqayam S. (2017). Many faces of rationality: implica­tions of the great rationality debate for clinical decision-making. Journal of Evaluation in Clinical Practice; 23(5): 915–922.
Croskerry P. (2009). A universal model of diagnostic reasoning. Academic
5. Medicine; 84(8): 1022–1028.
6. Durning SJ, Costanzo M, Artino AR et al. (2014). Using functional magnetic resonance imaging to improve how we understand, teach and assess clinical reasoning. Journal of Continuing Education in the Health Professions; 34(1): 76–82.
7.
Lubarsky S, Dory V, Audétat M et al. (2015). Using script theory to culti-
vate illness script formation and clinical reasoning in health professions education. Canadian Medical Education Journal; 6: e61–e70.
8. Prakash S, Sladek RM and Schuwirth L. (2019). Interventions to improve diagnostic decision making: a systematic review and meta-analysis on reflective strategies. Medical Teacher; 41(5): 517–524.
Kahneman D. Thinking, fast and slow. London: Penguin Books, 2011.
9.
10.
Stanovich KE. Rationality and the reflective mind. Oxford: OUP, 2011. Evans J and Frankish K (Eds). In two minds: dual processes and beyond.
11. Oxford: OUP, 2009.
12. Eva K. (2004). What every teacher needs to know about clinical reasoning. Medical Education; 39: 98–106.
13. Kaplan A. (2008). Clarifying metacognition, self-regulation, and self-regulated learning: what’s the purpose? Educational Psychology Review; 20: 47.
14.
Moulton CE, Regehr G, Mylopoulos M et al. (2007). Slowing down when
you should: a new model of expert judgment. Academic Medicine; 82(10): S109–S116.
Stanovich KE. Distinguishing the reflective, algorithmic, and autonomous
15. minds: is it time for a tri-process theory? In: Evans J and Frankish K (Eds). In two minds: dual processes and beyond. Oxford: OUP, 2009.
Thomas KE et al. (2002). The diagnostic accuracy of Kernig’s sign,
16. Brudzinski’s sign, and nuchal rigidity in adults with suspected meningitis. Clinical Infectious Diseases; 35(1): 46–52.
17.
Manzoor F and Redelmeier DA. (2019). The perils of teaching medical
triads. Medical Education; 53: 110–112.
Bransford JD, Brown AL and Cocking RR (Eds). How people learn: brain,
18. mind, experience and school. Washington DC: National Academies Press,
2000.
19. Ericsson KA. (2004). Deliberate practice and the acquisition and maintenance of expert performance in medicine and related domains. Academic Medicine; 79(10): S70–S81.
20. Croskerry P. (2018). Adaptive expertise in medical decision making. Medical Teacher; 40(8): 803–808.
21. Murthy VK, O’Brien B and Dhaliwal G. (2018). An inquiry into the early careers of master clinicians. Journal of Graduate Medical Education; 10(5): 500–506.
Further Resources
1. Zaharias G. (2018). What is narrative-based medicine? Narrative-based
medicine 1. Canadian Family Physician; 64(3): 176–180.
2. Lee SF. Logic: a complete introduction. Teach Yourself, 2017.
3. Fish D and de Cossart L. Developing the wise doctor. Royal Society of
Medicine Press, 2007.
CHAPTER 7
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Cognitive Biases
Nicola Cooper
OVERVIEW
• Biased decision-making significantly impacts individuals, institu­tions, and society as a whole
The extent to which cognitive biases contribute to diagnostic
• errors in medicine is debated
• There are different reasons why cognitive biases may occur
• Several different cognitive biases have been described
• Expert intuition plays an important role in expert professional practice
Introduction
Chapter 6 described how humans have two distinct processes when it comes to thinking and decision-making – one that is intu­itive and subconscious (Type 1 processing) and one that is analyt­ical and conscious (Type 2 processing). Type 1 processing makes use of associations that are either learned or inculcated by evolu­tionary processes. Many of our decisions are made through serial associations that do not involve conscious, effortful thinking – Croskerry gives the example of performing a well-learned act such as driving a car [1]. Much of this serial association is guided by heuristics (from the ancient Greek ‘I find, discover’) – simple, effi­cient rules or mental shortcuts. These rules work well under most circumstances, but in some cases can lead to systematic errors known as cognitive biases.
Since the 1970s, cognitive psychologists have examined the influence of heuristics on human decision-making and this has led to an explosion of what is known as the ‘heuristics and biases’ literature. Psychologists Tversky and Kahneman defined biased judgement and decision-making as that which systematically deviates from the prescriptions of objective standards such as facts, rational behaviour, statistics, or logic [2]. The reason why heuristics and biases are of such interest to psychologists is
because biased decision-making significantly impacts
individuals, institutions, and society as a whole – ranging from whether to get vaccinated, grant someone parole, or deciding whether Iraq has weapons of mass destruction [3].
The topic of cognitive biases in clinical reasoning, however, is controversial. This is partly because, as mentioned in Chapter 6, there are several key fallacies in the received view of dual pro­cess theories, including the beliefs that 1) Type 1 processes are always responsible for cognitive bias and Type 2 processing is always responsible for correct responses, 2) Type 1 processing is contextualised and Type 2 processing is abstract, and 3) fast processing is indicative of Type 1 processing [4]. It is also because studies in the psychology literature mainly involve general prob­lems specifically designed to induce biases in non-experts (see Box 7.1). There have been very few studies in medicine and none to date has been able to demonstrate that teaching about cognitive biases reduces diagnostic error. This may be in part because of what we know from non-medical education – meta­cognitive skills cannot be taught in isolation from the specific content at hand and attempts to teach them as generic may lead to a failure to transfer [5].
Box 7.1 A problem designed to induce heuristics and bias
An individual has been described by a neighbour as follows: ‘Steve is very shy and withdrawn, invariably helpful but with little interest in people or in the world or reality. A meek and tidy soul, he has a need for order and structure, and a passion for detail.’ Is Steve more likely to be a librarian or a farmer?
Answer: there are more than 20 male farmers for each male librarian in the United States, so Steve is more likely to be a farmer. But participants in this experiment ignore the relevant statistical facts and rely exclusively on resemblance.
From Kahneman D. (2011). Thinking, Fast and Slow. Penguin Books, London.
ABC of Clinical Reasoning, Second Edition. Edited by Nicola Cooper and John Frain. © 2023 John Wiley & Sons Ltd. Published 2023 by John Wiley & Sons Ltd.
42 ABC of Clinical Reasoning
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There is definitely agreement that cognitive biases exist in medicine, but disagreement as to whether they are a significant source of diagnostic errors compared with knowledge deficits. Norman et al. concluded it is likely that both cognitive biases and knowledge deficits contribute to errors. However, the existing lit­erature is simply insufficient to address the interplay and relative contributions of each [6].
This chapter will cover cognitive biases that are commonly encountered in clinical practice. The next chapter on situativity and human factors discusses the limitations of human performance further, and Chapter 9 explores cognitive strategies to avoid error.
Case History
A 75-year-old woman presented to hospital at around 5:00 p.m. with breathlessness. She had been told by her oncologist a few weeks before that she was anaemic, and to report to hospital if she got breathless or dizzy in case she needed a blood transfu­sion. Her haemoglobin at presentation was 84 g/L which was unchanged from previously. Her only past medical history was breast cancer for which she had had a mastectomy and was undergoing adjuvant chemotherapy. She was usually fit and independent and was not taking any regular medication apart from anti-emetics.
On examination, her vital signs were normal. Examination of the chest, heart, and abdomen was normal. Her 12-lead electro­cardiogram (ECG) and chest X-ray were normal. Apart from the haemoglobin of 84 g/L, her other blood tests (white cell count, platelets, electrolytes, calcium, and liver function tests) were normal. The emergency department doctor diagnosed breath­lessness due to anaemia and arranged for her to be admitted for a blood transfusion. The junior doctor on the acute medical unit also assessed the patient and said the same thing. At 11:00 p.m. the senior resident reviewed the patient’s case and said the same thing. Someone had requested a high sensitivity troponin T in the emergency department because the patient had mentioned brief palpitations, although she never had any chest pain. The troponin result was 126 ng/L (reference range 0–13 ng/L). The senior doc­tor therefore requested a repeat ECG and repeat troponin.
What are your thoughts at this point?
The next morning another senior resident and an oncology nurse specialist saw the patient and made preparations for a blood transfusion. Then the medical consultant saw the patient. Something did not seem quite right – the patient’s haemoglobin was 84 g/L when she did not have symptoms, so why was she breathless now? And what was this troponin result all about? It seemed very unlikely she had an acute coronary syndrome since she never had any chest pain and her 12-lead ECGs were normal. On further questioning, the patient said she was in the super­market the day before when she suddenly felt lightheaded, with associated palpitations and breathlessness. This lasted around 10 minutes and then settled down, but she had ‘not felt quite right’ since. An urgent computed tomography pulmonary angiogram was requested. This showed bilateral pulmonary emboli with right heart strain.
Analysis
Diagnostic momentum (see Figure 7.1) is the tendency for a diag­nosis to ‘stick’ despite a lack of supporting evidence. It involves sev­eral intermediaries – often starting as an opinion which may not even be medical, for example, the patient or a relative – and is passed with increasing certainty from one person to the next. Diagnostic labels become particularly sticky if a specialist has seen the patient.
However, there were several other things going on in this case,
including:
Anchoring
Search satisficing
Confirmation bias
Anchoring
Anchoring describes the common human tendency to rely too heavily on the first piece of information offered (the anchor) when making decisions. The initial piece of information (in this case, ‘I was told if I get breathless to come to hospital because it means I need a blood transfusion’) is used to make subsequent judgements. Once an anchor is set, other judgements are made by adjusting away from the anchor, and there is a bias towards inter­preting other information around it. Businesses use anchoring all the time – the ‘recommended retail price’ is an anchor. Salespeople use anchors to open negotiations. Several experiments have dem­onstrated the anchoring effect. In one example, estate agents were asked to estimate the value of a house. Beforehand they were given a randomly generated listed sales price. The higher the listed sales price, the higher they valued the property, although they denied being influenced by the anchor [7]. Lots of studies show that anchoring is very difficult to avoid, although experts may be more resistant to anchoring bias in their particular field.
Search Satisficing
Search satisficing is a term derived from the words ‘satisfy’ and ‘suf­fice’ – when we stop searching because we have found something that fits or is convenient, instead of systematically looking for the best alternative, which involves more effort. Satisficing is beneficial in everyday life – for example, when choosing from an extensive menu at a restaurant, or when there is an unlimited amount of information available and it is necessary to eliminate options and make a decision efficiently. However, in groups satisficing can be detrimental – for example, when people settle for a solution everyone can agree on even though it may not be the best one.
Wife:
‘I’m worried
you’re
having a
heart attack’
Figure 7.1 Diagnostic momentum. ACS=acute coronary syndrome.
Patient:
‘It feels like I’m having a heart attack’
Paramedic:
‘52-year-old
male with
possible
ACS’
Nurse:
‘You know
that man with ACS in cubicle 12?’
Doctor:
Documents
‘possible ACS’
in notes