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16.4 Treatment Options 223
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a b
Fig.16.3 Mucocoele expression. a place a finger against the side of the nose medially to the mucocoele. b While maintaining firm pressure against bone, roll the finger slowly onto the swelling towards the medial canthus
life without other intervention. Perform sac expression by placing a finger against the side of the nose just medially to the mucocoele (Fig. 16.3a). While maintain­ing firm pressure against bone, roll the finger slowly onto the swelling towards the medial canthus (Fig. 16.3b). Successful expression causes the mucocoele to disappear temporarily.
16.4.2 Lacrimal Probing (± Silicone Intubation)
16.4.2.1 Paediatric Probing
Lacrimal probing is indicated in symptomatic children whose mucocoele and watering have not resolved on expression alone during the first year or two of life. It requires a general anaesthetic but has a high success rate. Should the first probing fail to cure the child the second attempt should include nasal endoscopic control to confirm that the probe enters into the nose below the inferior turbinate. The second probing may be combined with the insertion of temporary silicone stents which are left in place for about two months (e.g., Nunchaku tubes®, FCI info@fci-ophthalmics.com).
Principle
Pass a smooth, blunt ended, probe through the lacrimal drainage passages to establish the site of any obstruction and possibly overcome it.
Steps
This technique is similar to lacrimal syringing up to the point of lacrimal sac entry.
1. Pull the lid laterally to straighten the canaliculus. Dilate the lacrimal punctum with a punctum finder-seeker, twirling it between your fingers as you push (Fig. 16.4a). The lid margin tension provides counter pressure to the punctal dilator.
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a
c
b
00
d
00
e
00
Fig.16.4 Lacrimal Probing. a Pull the lid laterally to straighten the canaliculus. Dilate the lacrimal punctum with a punctum finder-seeker. b Keeping the lid on lateral stretch insert a Bow­man 00-gauge lacrimal probe into the punctum perpendicularly. c Keeping the tip of the probe in the canaliculus rotate the probe laterally through 90°. d Advance the probe gently along the canaliculus until you reach a firm stop. e While maintaining gentle forward pressure on the probe, release the lid traction and rotate the probe’s axis 90° nasally to advance it into the nasolacrimal duct. Continue pushing the probe downwards until you reach an obstruction or encounter the floor of the nose (another ‘hard stop’)
2. Keeping the lid on lateral stretch insert a Bowman 00-gauge lacrimal probe into the punctum perpendicularly (Fig. 16.4b).
3. Keeping the tip of the probe in the canaliculus rotate the probe laterally through
°
(Fig. 16.4c).
90
4. Advance the probe gently along the canaliculus until you reach a firm stop (Fig. 16.4d). A so called ‘hard stop’ confirms that the tip has entered the lacrimal sac and is hitting the medial sac wall which lies on nasal bone. A ‘soft
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stop’ is when the probe springs back slightly when you release it. It means that the probe tip has encountered a fibrous obstruction within the canaliculus and has yet to enter the sac. If you encounter a soft stop abandon further prob­ing. You have localized a pre-sac obstruction, though it may not be the only obstruction in the drainage system.
5. While maintaining gentle forward pressure on the probe to keep it against the medial sac wall, release the lateral lid traction and rotate the probe’s axis 90 nasally to advance it into the nasolacrimal duct (Fig. 16.4e). Do this gently to avoid creating a false passage.
6. Continue pushing the probe downwards until you reach an obstruction or encounter the floor of the nose (another ‘hard stop’). A novice may find it difficult to distinguish between the two. Now apply more force to the probe. A membranous obstruction will give, and you will feel the probe tip advance to the nasal floor.
Note: Probing may be combined with nasal endoscopy to confirm nasal entry of the probe. However, nasal endoscopy requires skill and should not be undertaken without training.
16.4.2.2 Adult Probing
Lacrimal probing in adults has a low success rate as a treatment. It has been reported to succeed in 50% of cases when combined with silicone intubation, but only where no bony resistance is encountered in the nasolacrimal duct dur­ing probing. However, probing is sometimes helpful in confirming the site of an obstruction. Carry it out under general anaesthesia as adequate local anaesthesia of the entire drainage pathway is difficult to achieve.
o
16.4.3 Punctal Stenosis
A stenosed punctum is one that will not admit a 26 G lacrimal canula without dilatation. As dilatation with a punctum dilator/seeker has only a very temporary effect on patency use one of the more effective remedies below.
16.4.3.1 Perforated Punctum Plug (Fig. 16.5)
The most elegant solution for enlarging a stenosed punctum is to stent it for two months with a perforated punctum plug (FCI S.A.S.–Chirurgie Instrumentation, 20–22 rue Louis Armand, 75,015 PARIS–France). This is done under topical anaesthesia alone, does not damage the integrity of the punctal fibroelastic ring and allows some passage of tears while in place to discourage post-plug membrane formation.
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Fig.16.5 Perforated punctum plug. Polyvinylpyrrolidone surface modified silicone stent (to improve wettability)
Steps
1. Anaesthetise the eye with a drop of Proxymetacaine Hydrochloride 0.5%.
2. Place a small cotton wool pledget on the medial canthus, soak it with prox­ymetacaine and push it into the lower fornix behind the lower punctum, using the tip of the Minims® container. Wait several minutes for complete anaesthesia before removing the pledget.
3. Get the plug ready for insertion by opening its sterile packet.
4. Dilate the punctum with a punctum dilator/seeker, entering perpendicularly and then angling the dilator laterally while twisting and pushing it medially. Do this slowly to avoid tearing the fibrous ring.
Note: The punctum plug introducer has a punctum dilator at the other end. However, the taper on this is too short to make it useful.
5. Remove the dilator and insert the plug without delay as the fibrous ring will contract again rapidly.
6. After confirming correct insertion of the plug, remove the plug introducer by squeezing it. The plug should sit flush with the lid margin.
7. Remove the plug after 2–3 months under topical anaesthesia by pulling it out with Moorfields forceps. The punctum remains enlarged.
Note: The punctal stenosis may return after several years. The stenting treatment can be repeated if this happens.
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Fig.16.6 Nunchaku Lacrimal intubation. Silicone stenting tubing on introducer stylets
16.4.3.2 Lacrimal Intubation (Fig. 16.6)
Lacrimal intubation with a silicone tube is also an effective form of stenting for punctal stenosis but is more invasive and requires a general anaesthetic. Several types of tubes are available. The self-retaining Nunchaku® tubes (FCI) are partic­ularly easy to place and remove and are self-adjusting. The technique for inserting these tubes is the same as for lacrimal probing (above) with one added step. Once the tube on its introducer stylet is correctly positioned, grasp the stylet loosely with Moorfields forceps, just above the silicone tube. Use the forceps to prevent the tube from coming out as you withdraw the stylet.
An alternative form of intubation is to insert a self-retaining monocanalicu-
lar stent (e.g., LacriJet® FCI S.A.S.–Chirurgie Instrumentation, 20–22 rue Louis Armand, 75,015 PARIS–France). However, such punctum plug retained stents do not allow tear drainage while in place.
16.4.3.3 Punch Punctoplasty (Fig. 16.7)
This procedure is simpler and safer to perform than the previously popular, now hopefully obsolete, ‘three snip punctoplasty’ which it replaces. The latter is no­longer recommended as it damages the capillary action of the canaliculus. But even a punch punctoplasty causes damage to the punctal fibroelastic ring. It has not been shown to be superior to stenting alone.
Steps
1. Anaesthetise the eye with a drop of Proxymetacaine Hydrochloride 0.5%.
2. Place a small cotton wool pledget over the medial canthus and push it in place just behind the punctum and soak it using the tip of the proxymetacaine Minims® container. Wait a few minutes for complete anaesthesia.
3. Dilate the stenosed punctum and select the punctal wall to be removed. Choose the posterior wall if there is a slight punctal ectropion. If there is punctal entro­pion remove the anterior wall instead. A normally positioned punctum can be enlarged medially.
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a
c
Fig.16.7 Punch punctoplasty. a Open the punctum with a finder/seeker probe. b Use a punctum dilator to enlarge the punctum. c Use a Kelly’s punch to punch out one of the walls of the vertical portion of the canaliculus
b
4. Withdraw the punctum dilator and immediately insert the tip of a Kelly tra­beculectomy punch into the canalicular ampulla before the fibroelastic ring has time to contract again. Punch out the chosen punctal wall.
16.4.4 Punctal Inversion Surgery (Fig. 16.8)
Age related punctal ectropion is common. It used to be corrected by retro­punctal cautery or ‘tarsoconjunctival diamond excision’. To achieve correction using cautery an effective symblepharon must be created. This is undesirable as it limits independent movement between the eye and lid. Tarsoconjunctival diamond excision is futile for two reasons. Firstly, there is next to no tarsal plate below the punctum worth excising. Secondly, excising conjunctiva achieves nothing as it is too elastic to add inward traction.
Lower lid retractor plication to the sub-punctal tarsal plate on the other hand is
an effective alternative. It provides an active inward pull and is the mechanism by which retro-punctal cautery and diamond excision work on the occasions that they do.
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16.4.4.1 Steps
1. Make a short horizontal conjunctival incision 3–4 mm below the punctum, just inferior to the medial end of the tarsal plate (Fig. 16.8b).
2. Grasp and pull on the inferior conjunctival incision edge with Moorfields for­ceps. Insert closed scissors immediately under the conjunctiva and advance them infero-laterally by 10 mm. Open the scissors and withdraw to bluntly dissect a subconjunctival pocket from the incision to the middle of the inferior fornix (Fig. 16.8c).
a b
c
e
Fig.16.8 Punctal inversion surgery. a Punctal ectropion. b Make a horizontal conjunctival inci- sion below the punctum. c Bluntly dissect a subconjunctival pocket. d Engage the retractors with an absorbable suture, bring the needle out through the inferior edge of the tarsal plate below the punc­tum and re-insert it through the lower conjunctival edge. e Tie the suture tightly in the wound to bury the knot. f The retractors pull the punctum inwards on down-gaze. The suture knot is burried
d
f
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3. While still holding and gently stretching the conjunctiva, insert a pair of Jayles forceps into the pocket and grasp the lower lid retractors (found just anterior to the conjunctiva). Confirm that you have grasped the retractors by asking the patient to look down as far as possible. You should feel a tug on your forceps.
4. Ask the patient to look up while you pull the retractor aponeurosis out of the wound sufficiently to engage it with a 6/0 absorbable suture (Fig. 16.8d).
5. Bring the retractor suture needle out through the inferior edge of the tarsal plate below the punctum (Fig. 16.8e). Then re-insert the needle through the lower conjunctival edge, so that when tied the knot is buried.
6. Tie the suture tightly in the wound to bury the knot (Fig. 16.8f). This plicates the retractor directly to the posterior lamella below the punctum. From now on every time the patient looks down the retractors pull the punctum inwards.
16.4.5 Lid Margin Tightening
Watering from mild punctal ectropion may simply be a result of lower lid laxity. In this case (and after other possible explanations have been excluded) full thickness lid margin shortening (lateral Bick resection—Chap. 8) can cure the watering.
16.4.6 Lacrimal Drainage Surgery
Full surgical details of lacrimal drainage surgery are beyond this book’s remit and can be found in other texts. Here I shall only outline the factors that promote success.
16.4.6.1 Dacryocystorhinostomy (Fig. 16.9)
The gold standard lacrimal bypass surgery is an external dacryocystorhinostomy [2] (DCR). Its success rate is upwards of 90% if the obstruction is beyond the lacrimal sac (within the nasolacrimal duct). The role of concurrent silicone intubation in DCR remains uncertain. Factors that promote DCR success are:
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a b
c d
Fig.16.9 Dacryocystorhinostomy (DCR). Crosshatched bone is removed a to connect the sac directly to the nose b, making the lacrimal sac part of the nasal wall. This bypasses the blocked nasolacrimal duct. c Additionally, the crosshatched scarred common canaliculus is excised to con­vert a DCR into a Canaliculo-DCR (CDCR). d When not enough functioning canaliculus is present insert a glass bypass tube between the medial fornix and the nose
Adequate haemostasis
Creating a large bony ostium that spans the entire lacrimal sac bed
Complete opening of the lacrimal sac top to bottom
Suturing both the posterior lacrimal and nasal mucosal flaps to each other as well as the anterior flaps.
The aim of the surgery is to lay fully open the lacrimal sac and make it part
of the lateral wall of the nose (Fig. 16.9b) so that the sac as such ceases to exist. Surgical failures are usually due to not achieving the above aims. Mucosal scar contraction can result in partial or complete reformation of the lacrimal sac. The other cause of failure is pre-existing or surgically induced lacrimal canalicular scarring resulting in pre-sac obstruction and persistent symptoms. Endonasal DCR techniques are gaining popularity and in some hands the results equal those of the external approach. However, achieving the goals outlined above is more difficult via the limited endonasal access.
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16.4.6.2 Canaliculo-Dacryocystorhinostomy (CDCR)
Where the site of drainage obstruction is before the sac, and 8 mm of proxi­mal canaliculus is patent, the stenosed portion of the canaliculus can be resected (Fig. 16.9c). Perform a standard DCR but in addition probe the canaliculi and excise the stenosed portion. Then anastomose the cut ends of the canaliculi to the lateral sac wall and intubate the system.
16.4.6.3 Trans-Canalicular Endoscopic Surgery
The advent of ever smaller endoscopes has made trans-canalicular endoscopic surgery possible. Its place in routine lacrimal surgery remains to be established.
16.4.6.4 Lester-Jones Lacrimal Bypass Tube
When the canaliculi are insufficiently long for a CDCR the only remaining option is to bypass the drainage system completely with a Pyrex glass tube inserted between the medial conjunctival fornix and the nose (Fig. 16.9d). This can give very good symptomatic relief. However, it is an option of last resort as it commits the patient to lifelong follow up and tube maintenance. These tubes are prone to block with mucus and frequently become displaced (inwards or outwards).
16.4.6.5 Dacryocystectomy
Surgical removal of an infected lacrimal sac (dacryocystectomy) is an option for patients suffering recurrent dacryocystitis who are unfit for a DCR as it may be per­formed under local anaesthesia. It prevents further infections but does not address any watering issues. It is also indicated for the removal of lacrimal sac tumours.
16.5 Take Home Message
Watering of the eyes has multiple possible causes.
It significantly affects quality of life.
Accurate assessment is key to the correct management.
References
1. Kallarackal GU, Ansari EA, Amos N, Martin JC, Lane C, Camilleri JP (2002) A comparative
study to assess the clinical use of Fluorescein Meniscus Time (FMT) with Tear Break up Time (TBUT) and Schirmer’s tests (ST) in the diagnosis of dry eyes. Eye (Lond) 16(5):594–600.
https://doi.org/10.1038/sj.eye.6700177. PMID: 12194075
2. McNab AA (1994) Manual of Orbital and Lacrimal Surgery Hardcover. Churchill Livingstone
ISBN 0–443–04791-x