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B
C D
Fig. 9.3 Lateral radiograph (A) metallic marker and (B) diagram demonstrate a carpal boss at the base
of
the third metacarpal and capitate. Frontal radiograph (C) metallic marker and (D) diagram demonstrate
carpal boss and a theoretic depiction of associated displacement of the extensor carpi radialis brevis
the
tendon.
C, Capitate; ECRB, extensor carpi radialis brevis; ECRL, extensor carpi radialis longus; M2, sec-
metacarpal; M3, third metacarpal; T, trapezoid. (From Porrino J, Maloney E, Chew FS. Current con-
ond
cepts
of the carpal boss: pathophysiology, symptoms, clinical or imaging diagnosis, and management.
Prob Diag Radiol. 2015;44(5):462468 [Fig. 1]. ISSN 0363-0188,
Curr
diol.2015.02.008
,
http://www.sciencedirect.com/science/article/pii/S0363018815000274.)
https://doi.org/10.1067/j.cpra

138 9—A 48-YEAR-OLD MALE WITH A PAINFUL BUMP ON THE BACK OF HIS WRIST
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A
B C
Fig. 9.4 Radiographic manifestations of os styloideum. A lateral radiograph of the hand (A) demonstrates the osteophytic appearance of the extra ossification center (arrow). Clinically, a painless soft
tissue lump is often evident. In another patient, a similar outgrowth (arrows) is evident on lateral (B) and
frontal (C) radiographs. (From Resnick D. Diagnosis of Bone and Joint Disorders. 4th ed. Philadelphia:
Saunders; 2002:1312.)
from carpal boss syndrome. Carpal boss syndrome has a slight male predominance and a peak incidence in the middle of the third decade of life. Trauma is
often the common denominator in the development of carpal boss syndrome.
SIGNS AND SYMPTOMS
On physical examination, the carpal boss appears as a bony protuberance that
can be seen more easily by having the patient flex the wrist (Fig. 9.5). The pain
associated with this action can be reproduced by applying pressure to the soft
tissue overlying the carpal boss. Patients with carpal boss syndrome demonstrate a positive hunchback sign; that is, the examiner can appreciate a bony
prominence when palpating the carpal boss (see
inflamed bursa may overlie the bony excrudescence and may confuse the diagnosis as the normal hard consistency of the carpal boss may be masked by the
Fig. 9.2). Occasionally an

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Fig. 9.5 With wrist flexion, the prominence of the carpal boss becomes strikingly evident (arrow).
(From Park MJ, Namdari S, Weiss A-P. The carpal boss: review of diagnosis and treatment. J Hand
Surg. 2008;33(3):446449 [Fig. 2]. ISSN 0363-5023, https://doi.org/10.1016/j.jhsa.2007.11.029,
http://www.sciencedirect.com/science/article/pii/S0363502307011069.)
softer bursa. With acute trauma to the dorsum of the hand, ecchymosis over the
carpal boss of the affected joint(s) may be present. Unlike the ganglion cysts of
the wrist, which will transilluminate, the bony exostosis of the carpal boss will
not transilluminate.
TESTING
Plain radiographs are indicated in all patients who present with a carpal boss to
rule out fractures and to identify exostoses responsible for the symptoms (see
Figs. 9.3 and 9.4). Based on the patient’s clinical presentation, additional testing
may be warranted to exclude inflammatory arthritis, including a complete blood
count, erythrocyte sedimentation rate, uric acid level, and antinuclear antibody
testing. Magnetic resonance imaging (MRI), computerized tomography (CT),
and ultrasound imaging of the fingers and wrist are indicated if joint instability,
occult mass, occult fracture, infection, or tumor is suspected, as well as to further
assess the condition of the overlying tendons (
bone scanning may be useful to identify stress fractures (Fig. 9.8).
Figs. 9.6 and 9.7). Radionuclide

140 9—A 48-YEAR-OLD MALE WITH A PAINFUL BUMP ON THE BACK OF HIS WRIST
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AB
CD
Fig. 9.6 A 36-year-old man with an asymptomatic palpable mass at the dorsal surface of his right
wrist. Transverse (A) and longitudinal (B) ultrasound images obtained using a 12.5-MHz linear transducer on a Philips iu22 machine demonstrate a fragmented carpal boss at the dorsal base of the third
metacarpal (arrowheads), adjacent to the trapezoid (T) and capitate (C). A radiograph from the same
patient obtained with partial supination and ulnar deviation (C) improves conspicuity of the carpal boss
(arrowheads) relative to the routine lateral view (D). (From Porrino J, Maloney E, Chew FS. Current concepts of the carpal boss: pathophysiology, symptoms, clinical or imaging diagnosis, and management.
Curr Prob Diag Radiol. 2015;44(5):462468 [Fig. 4]. ISSN 0363-0188,
diol.2015.02.008
, http://www.sciencedirect.com/science/article/pii/S0363018815000274.)
https://doi.org/10.1067/j.cpra
DIFFERENTIAL DIAGNOSIS
The tentative diagnosis of carpal boss syndrome is made on clinical grounds and
is confirmed by radiographic testing. Arthritis, tenosynovitis, or gout of the
affected wrist may accompany carpal boss syndrome and exacerbate the
patient’s pain. Dorsal ganglion cysts may mimic the presentation of carpal boss.
Occasionally an inflamed bursa may overlie the bony excrudescence and may
confuse the diagnosis, as the normal hard consistency of the carpal boss may be
masked by the softer bursa (
clinical presentation. Other pathologic processes that may mimic the clinical presentation of carpal boss include fibromas, osteomas, exuberant synovium, fracture callus, and a variety of tumors (
Fig. 9.9). Occult fractures occasionally confuse the
Box 9.1).

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AB
CD
Fig. 9.7 A 28-year-old man with a palpable and painful mass at the dorsal surface of his left wrist.
Lateral radiograph (A) demonstrates a carpal boss at the base of the third metacarpal (arrowhead).
Sagittal (B) and coronal (C) computed tomography images demonstrate an osseous protuberance
emerging from the base of the third metacarpal and extending over the dorsal surface of the capitate
and trapezoid, consistent with a carpal boss (arrowheads). A three-dimensional reconstruction (D)
demonstrates the carpal boss at the base of the third metacarpal, overlying the quadrangular
trapezoid-capitate-metacarpal joint. M2, Second metacarpal; M3, third metacarpal. (From Porrino J,
Maloney E, Chew FS. Current concepts of the carpal boss: pathophysiology, symptoms, clinical or
imaging diagnosis, and management. Curr Prob Diag Radiol. 2015;44(5):462468 [Fig. 5]. ISSN
0363-0188,
article/pii/S0363018815000274
https://doi.org/10.1067/j.cpradiol.2015.02.008, http://www.sciencedirect.com/science/
.)

142 9—A 48-YEAR-OLD MALE WITH A PAINFUL BUMP ON THE BACK OF HIS WRIST
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AB
C
Fig. 9.8 A 39-year-old woman with dorsal wrist pain. Bone scan (A), acquired 3 hours after injection
of 32mCi Tc-99m methyl diphosphonate, demonstrates increased radiotracer uptake in the left wrist
(asterisk) compared with the right. Sagittal noncontrast computed tomography (B) and noncontrast
proton-density fat-saturated magnetic resonance (MR) (C) images demonstrate a carpal boss at the
base of the third metacarpal (arrowhead). Noncontrast axial T2 fat-saturated MR image (D) just proximal to the carpal boss demonstrates abnormal fluid in the tendon sheath of the extensor carpi radialis
brevis (arrowhead), consistent with tenosynovitis. (From Porrino J, Maloney E, Chew FS. Current concepts of the carpal boss: pathophysiology, symptoms, clinical or imaging diagnosis, and management.
Curr Prob Diag Radiol. 2015;44(5):462468 [Fig. 2]. ISSN 0363-0188,
2015.02.008
, http://www.sciencedirect.com/science/article/pii/S0363018815000274.)
D
https://doi.org/10.1067/j.cpradiol.

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Fig. 9.9 Occasionally an inflamed bursa may overlie the bony excrudescence and may confuse the
diagnosis, as the normal hard consistency of the carpal boss may be masked by the softer bursa.
(From Park MJ, Namdari S, Weiss A-P. The carpal boss: review of diagnosis and treatment. J Hand
Surg. 2008;33(3):446449 [Fig. 4]. ISSN 0363-5023, https://doi.org/10.1016/j.jhsa.2007.11.029,
http://www.sciencedirect.com/science/article/pii/S0363502307011069.)
BOX 9.1 ’ Differential Diagnosis of Carpal Boss
’
Ganglion cyst
’
Inflamed bursa
’
Synovitis
’
Fracture callus
’
Exuberant synovium
’
Fibroma
’
Giant cell tumor
’
Aneurysmal bone cyst
’
Unicameral bone cyst
’
Lipoma
’
Neural tumors
’
Interosseous ganglions
’
Osteoid osteoma
’
Osteochondroma
’
Osteosarcoma
’
Metastatic disease

r
144 9—A 48-YEAR-OLD MALE WITH A PAINFUL BUMP ON THE BACK OF HIS WRIST
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Inflamed tendon
and joint
Fig. 9.10 Injection technique for carpal boss, or os styloideum. (From Waldman SD. Carpal boss. In:
Atlas of Pain Management Injection Techniques. 2nd ed. Philadelphia: Saunders; 2007:268.)
Carpal boss
Trapezoid
Extenso
indicis
TREATMENT
Initial treatment of the pain and functional disability associated with a carpal
boss consists of nonsteroidal antiinflammatory drugs, simple analgesics, or
cyclooxygenase-2 inhibitors. Physical modalities, including local heat and gentle
range-of-motion exercises, should be introduced to avoid loss of function.
Vigorous exercises should be avoided because they will exacerbate the patient’s
symptoms. A nighttime splint to protect the fingers may be helpful. If sleep disturbance is present, low-dose tricyclic antidepressants are indicated. If the patient
does not respond to these conservative modalities, a trial of injection therapy with
local anesthetic and steroid is a reasonable next step (
exploration and removal of the carpal boss are requiredfor symptomatic relief.
Fig. 9.10). Rarely, surgical
HIGH-YIELD TAKEAWAYS
• The patient is afebrile, making an acute infectious etiology unlikely.
• The patient’s symptomatology is most likely due to trauma to the wrist from a
fall from a ladder.
• Physical examination and testing should be focused on the identification of the
other pathologic processes that may mimic the clinical diagnosis of carpa l boss.
• The patient exhibits the physical examination findings that are highly suggestive
of carpal boss.
• The patient’s symptoms are localized.
• Plain radiographs of the wrist will help identify bony abnormalities of the wrist,
including fractures, dislocations, and osseous tumors.
• Ultrasound imaging, CT scanning, and MRI of the wrist and pelvis may help
identify less common causes of wrist pain.

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Suggested Readings
Alemohammad AM, Nakamura K, El-Sheneway M, Viegas SF. Incidence of carpal boss
and osseous coalition: an anatomic study. J Hand Surg Am. 2009;34:1–6.
Capo JT, Orillaza NS, Lim PK. Carpal boss in an adolescent: case report. J Hand Surg
Am. 2009;34:1808–1810.
Ghatan AC, Erik JC, Edward AA, Andrew JW. Attrition or rupture of digital extensor
tendons due to carpal boss: report of 2 cases. J Hand Surg. 2014;39(5): 919–922.
Melone Jr. CP, Polatsch DB, Beldner S. Disabling hand injuries in boxing: boxer’ s
knuckle and traumatic carpal boss. Clin Sports Med. 2009;28:609–621.
Park MJ, Namdari S, Weiss AP: The carpal boss: review of diagnosis and treatment.
J Hand Surg Am. 2008;33:446–449.
Waldman SD. Carpal Boss. In: Atlas of Common Pain Syndromes. 4th ed. Philadelphia:
Elsevier; 2019:231–235.

CHAPTER
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10
Karen Carpenter
A 19-Year-Old Female With
Persistent Wrist Pain After Being
Thrown From a Horse
LEARNING OBJECTIVES
• Learn the common causes of wrist pain.
• Develop an understanding of the unique vascular anatomy of the scaphoid
bone.
• Develop an understanding of the causes of avascular necrosis of the scaphoid.
• Learn the clinical presentation of avascular necrosis of the scaphoid bone.
• Learn how to use physical examination to identify pathology of the scaphoid
bone.
• Develop an understanding of the treatment options for avascular necrosis of the
scaphoid bone.
• Learn the appropriate testing options to help diagnose avascular necrosis of the
scaphoid bone.
• Learn to identify red flags in patients who present with wrist pain.
• Develop an understanding of the role in interventional pain management in the
treatment of wrist pain.
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