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CHAPTER 6 The Nervous System
Posterior median
Anterior horn
fissure
column
Posterior white
Dorsal root
Mixed nerve
movement)
Fasciculus
temperature,
Descending tracts Ascending tracts
151
Substantia
gelatinosa
Posterior
horn
Lateral
horn
Lateral white
column
Central canal
septum
Anterior median
column
Anterior white
Dorsal root ganglion
Dorsal ramus
trunk
Ventral ramus
Grey matter
Ventral root
Fig. 6.7 Spinal cord in cross-section showing grey and white matter and spinal nerve roots.
Posterior columns – direct (position, vibration, touch)
Posterior spinocerebellar tract
Anterior spinocerebellar tract
Equilibrium
Crossed
pyramidal
tract
(voluntary
gracilis
Fasciculus cuneatus
Direct
pyramidal
tract
(voluntary
movement)
Lateral spinothalamic tract – crossed
Anterior spinothalamic tract – direct
Pain,
touch
Fig. 6.8 Cross-section of the spinal cord showing important ascending and descending tracts.
• bres in dorsal columns are uncrossed
• synapse in gracile and cuneate nuclei in medulla
• second-order bres cross in the sensory decussation whence they synapse in the thalamus
• third-order bres pass to the sensory cortex
• some bres pass from medulla to cerebellum along the inferior cerebellar peduncle.
• Posterior spinal arteries supply the posterior grey col­umns and dorsal columns on either side.
• Spinal artery reinforced at segmental level by radicular arteries, i.e. branches of the ascending cervical, cervical part of the vertebral, posterior intercostal and lumbar arteries.
• Radicular arteries may be compromised in resection of segments of the aorta in aneurysm surgery.
Blood Supply of the Spinal Cord
• Anterior and posterior spinal arteries from the vertebral arteries.
• Anterior spinal arteries supply the whole of the cord in front of the posterior grey columns.
Clinical Points
A cross-section of the spinal cord demonstrating the repre­sentation of the various areas in the spinal tracts is shown in Fig. 6.9.
152
Spinothalamic
Posterior
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SECTION I Anatomy
S
L
T
C
L
T
C
S
L
T
S
C
columns
Lateral corticospinal tract
tract
Fig. 6.9 Cross-section of the spinal cord showing
the representation of the cervical (C), thoracic (T), lumbar (L) and sacral (S) areas in the various spinal tracts.
A B
C D
Fig. 6.10 Incomplete spinal cord injury. (A) Anterior
cord syndrome. (B) Central cord syndrome. (C) Posterior cord syndrome. (D) Brown–Séquard syn­drome. The dark shaded area shows the region of the cord involved.
Complete Transection of Spinal Cord
• Total loss of voluntary movement distal to level of tran­section; this loss is irreversible.
• Loss of all sensation from those areas which depend on ascending pathways crossing the site of injury.
Incomplete Spinal Cord Injury (Fig. 6.10)
• Anterior cord syndrome:
• associated with exion/rotation injuries producing
anterior dislocation or compression fracture of verte­bral body with bone encroaching on the vertebral canal
• loss of power below level of lesion
• loss of pain and temperature below the lesion
• in addition to direct damage, the anterior spinal artery may be compressed
• the dorsal columns remain intact so that touch and proprioception are not aected.
• Central cord syndrome:
• occurs in syringomyelia and centrally placed tumours
• initially involves decussating spinothalamic bres so that pain and temperature are lost below the lesion
• later the lateral corticospinal tract is involved, with the more centrally placed cervical tract supplying the arm being involved more than the peripheral tracts supplying the legs. Classically there is accid weak­ness of the arms, but because the distal leg and sacral motor and sensory bres are spared, perianal sensa­tion and some leg movement and sensation may be preserved
• proprioception and ne touch are preserved in the dorsal columns until late.
• Posterior cord syndrome:
• seen in hyperextension injuries with fractures of the posterior elements of the vertebra
• loss of proprioception with profound ataxia with unsteady and faltering gait
• usually good power and pain and temperature sensa­tion below the lesion.
• Brown–Séquard syndrome:
• hemisection of the cord
• stab injury or damage to lateral mass of vertebrae
• paralysis on aected side below lesion (pyramidal tract)
• loss of proprioception and ne discrimination (dor­sal columns) on aected side below lesion
• loss of pain and temperature on opposite side below lesion (normal on aected side because of decussa­tion below level of hemisection)
• therefore the uninjured side has good power, but absent sensation to pinprick and temperature.
• Cauda equina syndrome:
• compression of lumbosacral nerve roots below the conus medullaris
• caused by bony compression or disc protrusion in the lumbosacral area
• lower motor neuron lesion
• bowel and bladder dysfunction together with leg numbness and weakness.
THE MENINGES
• Dura mater.
• Arachnoid mater.
• Pia mater.
CHAPTER 6 The Nervous System
153
Dura Mater
• Outer endosteal layer.
• Inner meningeal layer.
• Meningeal layer continuous into vertebral canal as dura covering spinal cord.
• e two layers are fused together except where they form the walls of dural venous sinuses.
• Folds of dura mater divide the cranial cavity into compartments.
• ese folds are:
• falx cerebri
• tentorium cerebelli
• falx cerebelli.
Falx Cerebri
• Lies between the two cerebral hemispheres.
• Attached anteriorly to crista galli.
• Attached posteriorly to tentorium cerebelli.
• Superior sagittal sinus lies in its attached superior border.
• Inferior sagittal sinus lies in its free inferior border.
• e straight sinus is seen where the falx meets the tento­rium cerebelli.
Tentorium Cerebelli
• Attached anteriorly to the posterior clinoid process of sphenoid bone.
• Attachment runs posteromedially along the superior border of the petrous temporal bone where superior petrosal sinuses enclosed.
• Where latter empties into transverse sinus, attached border runs posteromedially along the lips of the groove for the transverse sinus to reach the internal occipital protuberance.
• It then continues on the opposite side of the skull to reach the other posterior clinoid process.
• Free border of tentorium is attached to anterior clinoid processes.
• Runs posterior and medially, curving round the mid­brain, forming tentorial notch.
• Just behind the apex of the petrous temporal bone, the inferior layer prolongs into the middle cranial fossa as the trigeminal cave.
Falx Cerebelli
• Lies between the two lateral lobes of the cerebellum.
• Lies below the tentorium in the posterior cranial fossa.
Diaphragma Sellae
• Fold of dura forming the roof of the pituitary fossa.
• Covers the pituitary gland and has an opening through which the infundibulum passes.
Arachnoid Mater
• Separated from dura by subdural space.
• e subarachnoid space contains cerebrospinal uid (CSF) and major blood vessels.
• Arachnoid and subarachnoid spaces extend into ver­tebral canal to the level of the second piece of the sacrum.
• Deep surface of the arachnoid projects into the venous sinuses to form arachnoid villi; these are most numer­ous along the superior sagittal sinus. Collections of arachnoid villi are known as arachnoid granulations.
• Arachnoid granulations are sites of reabsorption of CSF into superior sagittal sinus and probably other dural sinuses.
Subarachnoid Cisterns
• Subarachnoid space varies in size as arachnoid follows surface of dura and pia follows surface of brain.
• is arrangement gives rise to cisterns:
• cerebellomedullary cistern (cisterna magna): poste-
rior to medulla below cerebellum
• pontine cistern: anterior to pons
• interpeduncular cistern: between cerebral peduncles
and optic chiasma—contains circle of Willis and cra­nial nerves III and IV.
Pia Mater
• Closely follows surface of brain.
• Dips down to sulci.
• Blood vessels enter brain in a sleeve of pia mater.
• At the choroid ssure of lateral ventricles and the roof of the third and fourth ventricles, the pia is invaginated by blood vessels to form the tela choroidea and choroid plexus.
Production and Circulation of CSF
• Produced by choroid plexus in all four ventricles.
• Flows from lateral ventricles to third ventricle to cere­bral aqueduct to fourth ventricle to subarachnoid space.
• Absorbed into venous system through arachnoid granu­lations along dural venous sinuses.
• e interventricular foramen (of Monro) connects the lateral ventricle to third ventricle.
• e fourth ventricle has three openings on its roof which connect it to the subarachnoid space:
• the foramen of Magendie in the midline
• the paired foramina of Luschka laterally.
• rough these, CSF ows from the ventricular system into the subarachnoid space.
• Total volume about 100–150 mL.
• Pressure 8–10 cmH2O.
154
Anterior cerebral artery
communicating
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SECTION I Anatomy
Blood Supply to the Brain (See Fig. 5.22)
• Two vertebral arteries.
• Two internal carotid arteries.
Vertebral Arteries
• Enter cranial cavity via foramen magnum.
• Lie in subarachnoid space.
• Unite at lower border of pons to form basilar artery.
Branches
• Posterior spinal artery.
• Anterior spinal artery.
• Posterior inferior cerebellar artery.
Basilar Artery
Branches
• Anterior inferior cerebellar.
• Labyrinthine artery.
• Pontine arteries.
• Superior cerebellar arteries.
• Posterior cerebral artery (terminal branches of basilar artery) supplies visual area of occipital lobe; occlusion causes blindness in contralateral visual eld.
Internal Carotid Arteries
Branches
• Posterior communicating artery.
• Anterior cerebral artery.
• Middle cerebral artery.
• Anterior choroidal artery.
Middle Cerebral Artery
• Larger of terminal branches of internal carotid artery.
• Supplies lateral surface of frontal, parietal and temporal lobes (except narrow strips supplied by anterior cerebral artery).
• Occlusion results in contralateral motor and sensory paralysis of face and arm.
Anterior
communicating
artery
Posterior
artery
Basilar artery
Anterior inferior
cerebellar artery
Posterior inferior cerebellar artery
Fig. 6.11 The circle of Willis. The central arteries sup-
ply the corpus striatum, internal capsule, diencepha­lon and midbrain.
Internal carotid artery
Central arteries
Posterior cerebral artery
Pontine
}
branches
Labyrinthine artery
Vertebral artery
Middle cerebral artery
Superior cerebellar artery
Venous Drainage of Brain
e veins lie alongside the arteries in the subarachnoid space. ey pierce the pia mater and drain into the dural venous sinuses. e major veins are:
• superior cerebral veins
• supercial middle cerebral vein
• basal vein
• great cerebral vein.
Circle of Willis (Fig. 6.11)
• Formed by the two vertebral and two internal carotid arteries on the inferior surface of the brain.
• Each half of the circle is formed by:
• anterior communicating artery
• anterior cerebral artery
• internal carotid artery
• posterior communicating artery
• posterior cerebral artery.
• Despite interconnection, there is only minimal mixing of blood passing through the arteries.
• When one artery is blocked the arterial circle may pro­vide collateral circulation.
Dural Venous Sinuses (Fig. 6.12)
• Situated within the dura mater.
• Devoid of valves.
• Drain eventually into internal jugular vein. e cranial venous sinuses are:
• superior sagittal sinus
• inferior sagittal sinus
• straight sinus
• transverse sinus
• sigmoid sinus
• conuence of sinuses
• occipital sinus
• cavernous sinus.
Inferior sagittal sinus
Inferior petrosal sinus
Right transverse sinus
Superior sagittal sinus
Superior petrosal sinus
CHAPTER 6 The Nervous System
Falx cerebri
155
Fig. 6.12 The venous sinuses.
• Commences at crista galli.
• Courses backwards along attached border of falx cerebri.
• Usually becomes continuous with right transverse sinus
• Venous lacunae lie along its course and open into the
• Sinus and lacunae are invaginated by arachnoid
• Superior cerebral veins drain into superior sagittal sinus.
• Lies along inferior border of falx cerebri.
• Receives cerebral veins from medial surface of
• Joins great cerebral vein to form straight sinus.
• Formed by union of inferior sagittal sinus and great
• Lies in attachment of falx cerebri to tentorium cerebelli.
• Usually becomes continuous with le transverse sinus
• Lies in groove on inner surface of occipital bone along
• On reaching petrous temporal bone it curves down-
Sphenoparietal sinus
Cavernous sinus
Superior sagittal sinus
at the internal occipital protuberance.
sinus.
granulations.
Inferior sagittal sinus
hemispheres.
Straight sinus
cerebral vein.
near internal occipital protuberance.
Transverse sinus
posterior attachment of tentorium cerebelli.
wards into posterior cranial fossa to follow a curved course as sigmoid sinus.
Straight sinus
Tentorium cerebelli
Sigmoid sinus
• Passes through jugular foramen.
• Becomes continuous with internal jugular vein.
Confluence of sinuses
• Formed by the two transverse sinuses near the internal occipital protuberance.
Occipital sinus
• Small sinus extending from foramen magnum.
• Drains into conuence of sinuses.
• Lies along falx cerebelli and connects vertebral venous plexuses to transverse sinus.
Cavernous sinus (Fig. 6.13)
• One on each side.
• Situated on body of sphenoid bone.
• Extends from superior orbital ssure to apex of petrous temporal bone.
• Relations:
• medially: pituitary gland and sphenoid sinus
• laterally: temporal lobe of brain.
• Internal carotid artery and abducens nerve (VI) pass through it.
• On the lateral wall from above down are:
• oculomotor nerve (III)
• trochlear nerve (IV)
• ophthalmic nerve (V)
• maxillary nerve (V).
• Ophthalmic veins drain into the anterior part of sinus.
156
Optic nerve
Hypophysis cerebri
Oculomotor nerve
Ophthalmic nerve
Abducens nerve
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SECTION I Anatomy
Diaphragma sellae
Hypophyseal stalk
Cavernous sinus Trochlear nerve Pia
Fig. 6.13 The cavernous sinus.
• Posteriorly the sinus drains into the transverse or
• Emissary veins passing through the foramina of the
• e two sinuses are connected by anterior and posterior
Clinical Points
• Cavernous sinus thrombosis may occur as a result of
• Blockage of the venous drainage of the orbit consequent
CRANIAL NERVES
I Olfactory Nerve
• Axons from olfactory mucosa in nasal cavity pass
Sphenoid air sinus
Internal carotid artery
sigmoid sinus through superior and inferior petrosal sinuses.
middle cranial fossa connect the cavernous sinus to the pterygoid plexus and facial veins.
intercavernous sinuses lying in front of and behind the pituitary gland, respectively.
spread of infection from the lips and face via the ante­rior facial and ophthalmic veins, or from deep infec­tions via the pterygoid venous plexus, all of which drain into the sinus.
on cavernous sinus thrombosis results in a characteristic clinical picture:
• oedema of the conjunctiva and eyelids
• exophthalmos with transmitted pulsations from the internal carotid artery
• ophthalmoplegia due to pressure on the contained cranial nerves
• ophthalmoscopy demonstrates papilloedema and retinal haemorrhages.
through the cribriform plate of the ethmoid bone to end in the olfactory bulb.
Arachnoid
Maxillary nerve
• A cu of dura, arachnoid and pia mater surrounds each bundle of nerves.
• Synapse with mitral cells in olfactory bulb.
• Axons of mitral cells pass backwards in the olfactory tract to terminate in the cortex of the uncus.
Clinical Points
• Head injuries involving fractures in the anterior cranial fossa may sever the olfactory nerves, resulting in bilat­eral anosmia. In addition, fractures in the anterior cra­nial fossa may also cause CSF rhinorrhoea.
• Unilateral anosmia may be a sign of frontal lobe tumours.
• Olfactory cortex consists of the uncus and anterior per­forated substance.
• Tumours in the region of the uncus may result in an ‘uncinate t’, characterized by olfactory hallucinations associated with impairment of consciousness and invol­untary chewing movements.
II Optic Nerve (Fig. 6.14)
• Commences at lamina cribrosa, where axons of gan­glion cells of retina pierce sclera.
• Covered by dura, arachnoid and pia mater, it runs pos­teromedially in the orbit to enter the optic canal.
• Accompanied by the ophthalmic artery.
• Reaches the optic groove on the dorsum of the body of sphenoid bone.
• Fibres from medial half of retina, i.e. temporal visual eld, cross over in the optic chiasma to the optic tract of the opposite side.
• Fibres from the lateral half of the retina, i.e. nasal visual eld, pass backwards in the optic tract of the same side.
CHAPTER 6 The Nervous System
Medial half of retina
Optic
geniculate
cortex
157
Optic
nerve
Lateral half of retina
Optic chiasm
tract
Lateral
body
Visual
Fig. 6.14 The visual pathways.
Optic radiation
• Optic tract passes posterolaterally from the optic chiasma.
• e majority of bres in the optic tract end in the lateral geniculate body of thalamus.
• A small proportion of optic tract bres bypass the lat­eral geniculate body, ending in the superior colliculus or pretectal nucleus. ese bres subserve pupillary, ocular and head and neck reexes (aerent limb of light reexes).
• From the lateral geniculate bodies, bres of the optic radiation pass laterally and backwards to the visual cor­tex of the occipital lobe.
• e upper half of the retina is represented in the upper lip of the calcarine ssure, the lower half on the lower lip.
Clinical Points
• Lesions of the optic nerve result in ipsilateral blindness.
• Lesions of the optic tract and central visual pathway result in contralateral homonymous hemianopia.
• Lesions of the optic chiasma (e.g. from expanding pitu­itary lesions) will cause bitemporal hemianopia (loss of vision of both temporal elds).
• inferior oblique
• levator palpebrae superioris.
2. Preganglionic parasympathetic bres supplying the sphincter of the pupil via the ciliary ganglion.
• Somatic eerent nucleus (ocular muscles and
Edinger–Westphal nucleus; parasympathetic) lie in midbrain at level of superior colliculus.
• Oculomotor nerve emerges between cerebral
peduncles.
• Passes forwards between superior cerebellar
artery and posterior cerebral artery.
• Pierces dura to lie on lateral wall of cavernous
sinus.
• Divides into superior and inferior branch before
entering into superior orbital ssure.
• Superior division supplies superior rectus and
levator palpebrae superioris.
• Inferior division supplies medial rectus, inferior
rectus and inferior oblique.
• Parasympathetic bres leave the branch to the
inferior oblique to synapse in the ciliary ganglion (lies at the apex of the orbit just lateral to the optic nerve).
• Postganglionic bres pass to ciliary muscles and
constrictor pupillae via the short ciliary nerves.
• Stimulation of the nerve results in pupillary con-
striction and accommodation of the lens.
Clinical Points
• Complete division of the nerve results in:
• ptosis, due to paralysis of levator palpebrae superioris
• divergent squint, caused by unopposed action of lat­eral rectus and superior oblique
• dilatation of the pupil, caused by unopposed action of dilator pupillae (supplied by sympathetic bres in the long ciliary branches in the nasociliary nerve)
• loss of accommodation and light reexes, due to paralysis of ciliary muscles and constrictor pupillae
• diplopia.
• Oculomotor nerve may be paralysed by:
• aneurysm of posterior cerebral, superior cerebellar and posterior communicating arteries
• raised intracranial pressure associated with hernia­tion of uncus into tentorial notch
• tumours in region of sella turcica.
III Oculomotor Nerve
• Two main components:
1. Somatic motor bres supplying:
• superior rectus
• inferior rectus
• medial rectus
IV Trochlear Nerve
• Smallest cranial nerve.
• Supplies superior oblique muscle.
• Nucleus lies at level of inferior colliculus.
• Fibres pass dorsally around cerebral aqueduct and decussate in superior medullary velum.
158
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SECTION I Anatomy
• Emerges from dorsum of pons (only cranial nerve to arise from dorsum of brainstem).
• Winds round cerebral peduncle.
• Passes forwards between superior cerebellar and poste­rior cerebral arteries to pierce dura.
• Runs forward on lateral wall of cavernous sinus between oculomotor and ophthalmic nerves.
• Enters orbit through superior orbital ssure lateral to tendinous ring from which recti take origin.
• Passes medially over optic nerve to enter superior oblique muscle.
Clinical Point
• Injury to trochlear nerve results in paralysis of superior oblique, resulting in diplopia when patient looks down­wards and laterally. e patient complains of diculties when walking downstairs.
V Trigeminal Nerve
e trigeminal nerve comprises three divisions:
• ophthalmic: sensory
• maxillary: sensory
• mandibular: mixed sensory and motor.
It is distributed as follows:
• sensory: to face, scalp, teeth, mouth, nasal cavity, para­nasal sinuses and most of dura mater
• motor: to muscles of mastication, mylohyoid, anterior belly of digastric, tensor tympani and tensor palati
• ganglionic connections to the ciliary, sphenopalatine, otic and submandibular ganglia.
e nuclei of the trigeminal nerve lie as follows:
• Motor nucleus:
• situated in upper part of pons near oor of fourth
ventricle.
• Sensory nuclei:
• mesencephalic nucleus (concerned with propriocep-
tion) is in the midbrain
• the chief sensory nucleus, concerned with touch,
tactile discrimination and position sense, lies in the pons
• the nucleus of the spinal tract, concerned with
pain and temperature, is in the medulla and extends caudally into the upper segments of the spinal cord.
Trigeminal Ganglion
• Lies in invaginated pocket of dura in the middle cranial fossa.
• Lies near apex of petrous temporal bone in a hollow (Meckel’s cave).
• Motor root of nerve and greater supercial petrosal nerve pass deep to ganglion.
• Hippocampal gyrus of temporal lobe lies above.
• Medially lies the internal carotid artery and part of the cavernous sinus.
Ophthalmic Division
• Smallest division.
• Wholly sensory.
• Innervates skin of forehead, upper eyelid and most of nose.
• Passes forwards to enter lateral wall of cavernous sinus.
• Lies below trochlear nerve in cavernous sinus.
• Divides into three branches just before entering orbit:
1. Frontal:
• runs forwards beneath roof of orbit
• divides into supratrochlear and supraorbital nerves supplying upper eyelid and scalp as far back as the lambdoid suture.
2. Lacrimal:
• to lacrimal gland via postganglionic parasym­pathetic bres from pterygopalatine ganglion, which it reaches via the maxillary nerve
• to the lateral part of the conjunctiva and upper eyelid.
3. Nasociliary:
• to ciliary ganglion
• eyeball
• cornea and conjunctiva of medial part of upper eyelid
• dura of anterior cranial fossa
• mucosa and skin of nose.
Maxillary Division
• Wholly sensory.
• Passes forwards to leave skull through foramen rotundum.
• Emerges into pterygopalatine fossa.
• Continues through inferior orbital ssure and infraor­bital canal, becoming the infraorbital nerve supplying the skin of the cheek and lower eyelid.
• Branches:
• zygomatic, giving zygomaticotemporal and zygo-
maticofacial branches to the skin of the temple and cheek, respectively
• superior alveolar branches to teeth of upper jaw
• branches from the pterygopalatine ganglion.
Pterygopalatine ganglion
• Lies in pterygopalatine fossa.
• Receives parasympathetic (secretomotor) root via the greater supercial petrosal branch of cranial nerve VII; sensory component from two pterygopalatine branches of maxillary nerve; and sympathetics from the internal carotid plexus.
CHAPTER 6 The Nervous System
159
• Parasympathetic eerents pass to lacrimal gland.
• Sensory and sympathetic bres to nose, nasopharynx, palate and orbit.
Mandibular Division
• Largest division.
• Motor and sensory.
• Supplies:
1. Sensory:
• skin of temporal region
• part of auricle
• lower face
• mucous membrane of the anterior two-thirds of the tongue and oor of the mouth.
2. Motor:
• muscles of mastication.
3. Parasympathetic:
• secretomotor to parotid gland.
• Passes forwards from trigeminal ganglion to enter fora­men ovale.
• Gives o nervus spinosus to supply dura mater and nerve to medial pterygoid, from which otic ganglion is suspended.
• Divides into small anterior and large posterior trunk.
• Anterior trunk:
• sensory branch, i.e. buccal nerve to skin of cheek and
mucous membrane of cheek
• motor to masseter, temporalis and lateral pterygoid.
• Posterior trunk:
• auriculotemporal nerve (sensory to temple and auri-
cle; secretomotor bres from otic ganglion to parotid gland)
• lingual nerve:
• parasympathetic secretomotor bres from the chorda tympani join the lingual nerve to supply the submandibular gland
• terminal branches are distributed to the anterior two-third of the tongue, the oor of the mouth and the lingual surface of the gums
• inferior alveolar nerve:
• enters mandibular canal and supplies teeth of lower jaw
• emerges through mental foramen, supplying skin of chin and lower lip
• also supplies motor nerves, i.e. nerve to mylohy­oid, supplying mylohyoid and anterior belly of digastric.
Otic Ganglion
• Lies immediately below foramen ovale, lying close to the medial surface of the mandibular nerve.
• Parasympathetic bres through the lesser supercial petrosal branch of the glossopharyngeal nerve relay in
the ganglion, and pass via the auriculotemporal nerve to the parotid as secretomotor supply.
• Sympathetic bres—from plexus on middle meningeal artery—are vasoconstrictor.
• Sensory bres via auriculotemporal nerve to parotid gland.
• Motor bres (not present in any other cranial ganglion) pass through the ganglion from the nerve to medial pterygoid to supply tensor tympani and tensor palati.
Submandibular Ganglion
• Lies between hyoglossus and deep part of submandibu­lar gland.
• Suspended from lower aspect of lingual nerve.
• Parasympathetic bres from chorda tympani of facial nerve conveyed by lingual nerve carrying secretomotor bres to sublingual and submandibular gland.
• Sympathetic bres from superior cervical ganglion via plexus on facial artery supply vasoconstrictor bres to sublingual and submandibular glands.
• Sensory component via lingual nerve to salivary glands and mucous membrane of oor of mouth.
Clinical Points
• Division of the whole trigeminal nerve results in uni­lateral anaesthesia of the face and the anterior part of the scalp, the auricle, and the mucous membranes of the nose, mouth and anterior two-thirds of tongue. Paralysis and wasting of the muscles of mastication occur on the aected side.
• Pain is frequently referred from one segment to another. A patient with a carcinoma of the tongue (lingual nerve) may complain of earache (via the auriculotemporal nerve). e classical description used to be the case of an elderly man sitting in outpatients spitting blood with a piece of cotton wool in his ear.
VI The Abducens Nerve
• Supplies lateral rectus.
• Nucleus in oor of fourth ventricle in upper part of pons.
• Fibres of facial nerve wind round nucleus to form facial colliculus.
• Emerges between medulla and pons.
• Passes forwards through pontine cistern.
• Pierces dura mater to enter cavernous sinus lying on lat­eral aspect of internal carotid artery.
• Enters orbit through tendinous ring at superior orbital ssure.
Clinical Points
• Has a long intracranial course and therefore frequently involved in injuries to base of skull.
• Damage gives rise to diplopia and a convergent squint.
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SECTION I Anatomy
VII Facial Nerve
• Supplies muscles of facial expression.
• Conveys parasympathetic bres to:
• lacrimal gland
• glands in nasal cavity
• submandibular salivary glands
• sublingual salivary glands.
• Transmits taste bres from anterior two-thirds of tongue.
• Motor nucleus in lower pons.
• Motor bres loop round abducens nerve nucleus (facial colliculus) and emerge at cerebellopontine angle with nervus intermedius (contain sensory and parasympa­thetic bres).
• Sensory bres synapse in nucleus of tractus solitarius in the pons.
• Autonomic bres originate in the superior salivary nucleus in the pons.
• Nervus intermedius lies lateral to motor bres of facial nerve in between latter and vestibulocochlear nerve.
• Motor bres of facial nerve and nervus intermedius pass through the pontine cistern and enter the internal acoustic meatus, where the two join together to form the facial nerve.
• Nerve then passes through facial canal in petrous tem­poral bone.
• Runs laterally over vestibule to reach medial wall of middle ear, where it bends sharply backwards over the promontory.
• is sharp bend, the genu, has the geniculate ganglion.
• Nerve passes downwards on posterior wall of middle ear to emerge through the stylomastoid foramen at the base of the skull.
• Branches given o in the petrous temporal bone are:
• greater petrosal nerve
• nerve to stapedius
• chorda tympani.
• Greater petrosal nerve transmits preganglionic para­sympathetic bres to sphenopalatine ganglion, the postganglionic bres supplying the lacrimal glands and nasal cavity glands.
• Chorda tympani carries parasympathetic bres to sub­mandibular and sublingual salivary glands and taste bres from anterior two-thirds of tongue.
• Aer emerging from the stylomastoid foramen, the nerve enters the parotid gland and divides into the fol­lowing branches:
• temporal
• zygomatic
• buccal
• mandibular
• cervical.
• Testing of individual branches of the facial nerve is important aer head and neck surgery, e.g. supercial parotidectomy. e following tests may be carried out to assess the various branches of the facial nerve:
• to test frontalis, ask patient to raise eyebrows.
Normally wrinkles are seen on the forehead. Tests temporal branch
• to test orbicularis oculi, ask patient to close eyelids
tightly against resistance. Tests temporal and zygo­matic branches
• to test levator anguli oris, ask patient to show teeth to
check that the angles of the mouth move equally on both sides. Tests buccal branch
• to test orbicularis oris, ask patient to purse lips
tightly against resistance. Tests buccal and marginal mandibular branch
• to test buccinators, ask patient to blow out the cheeks,
keeping the mouth shut. Tap the cheek to see if air escapes from the closed mouth. Tests buccal branch
• to test risorius, ask patient to smile. e angle of the
mouth will not move on the side of the lesion. Tests buccal nerve
• to test depressor anguli oris (draws the angle of
the mouth downwards and laterally), ask patient to smile. e lower lip on the side of the lesion remains elevated thus distorting the smile. Tests marginal mandibular branch
• to test platysma, ask patient to clench the teeth and
simultaneously depress the angles of the mouth. Normally, longitudinal folds of skin become obvious in the neck when platysma contracts. Tests cervical branch.
Clinical Points
• Infranuclear paralysis may be caused by malignant tumours of the parotid, parotid surgery, acoustic neu­roma and its surgery, and fracture of the base of the skull.
• It is important to distinguish between a supranuclear facial palsy and a nuclear or infranuclear facial palsy.
• Nuclear and infranuclear palsy aects all muscles on the same side of the face.
• Supranuclear palsy aects contralateral facial muscles but spares the frontalis and orbicularis oculi, since the part of the facial nucleus supplying these muscles receives bres from both cerebral hemispheres, i.e. there is bilateral cortical representation. Supranuclear palsy is likely to result from cerebrovascular accidents involv­ing the corticobulbar pathways. If a patient with a right cortical defect is asked to look up and smile, the patient will be unable to raise the le side of the mouth but the