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F. Yaylak and M. Özsoy
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Table 16.1 Types, procedures, aims, and rationale for prophylactic surgery of small intestines
Type prophylactic surgery Procedure Aim and rationale for prophylaxis Ref
Primary Hernia repair To prevent hernia-related strangulation in asymptomatic patients
Intestinal resection To prevent complications related to Meckel’s diverticulum in
Endoscopic or surgical drainage
Endoscopic or surgical polypectomy
Closure of omental or mesenteric openings
Secondary Loop ileostomy Decompression of a distal ileoanal or ileorectal anastomosis after
Feeding jejunostomy
Miscellaneous Permanent access
for ERCP
Intestinal auto­transplantation
with any abdominal wall hernias, which may cause intestinal loss and merit resection
asymptomatic patients To prevent duplication cyst related mass effect. Cyst is drained, a
partial cyst removal or fenestration may be performed To prevent cancer development in polyposis syndromes [
To prevent internal herniation after a gastric bypass surgery for obesity surgery
a total proctocolectomy of colectomy, or a colorectal or coloanal anastomosis after an anterior resection
Endoscopic or surgical feeding jejunostomies are aimed to prevent a future surgery for intestinal feeding access. Mainly performed during any abdominal surgeries with no current and clear indication for intestinal feeding, such as a pancreaticoduodenectomy
To access to biliary tract for endoscopic procedures a subcutaneous blind isolated loop of jejunum is constructed after a roux-Y hepaticojejunostomy
[
13]
410]
[
[11, 12]
13, 14]
[15, 16]
[1720]
2123]
[
[
24, 25]
26]
[
Surgical procedures for primary prophylactic sur­geries may include abdominal or inguinal hernia repairs, intestinal resections, endoscopic or surgi­cal drainage of a duplication, an abscess or a cyst, endoscopic or surgical removal of a polyp, clo­sure of an omental or mesenteric openings after a major abdominal surgery. Types, surgical proce­dures, and aims or rationale for prophylaxis have been reviewed in Table16.1.
16.3.1 Primary Prophylactic Surgeries for Small Intestines
16.3.1.1 Prophylactic Hernia Repair
Abdominal wall hernias are common in our daily surgical practice. As an historical viewpoint, diag­nostic criteria and indications for hernia surgery are clearly dened and surgical procedures are rened and nearly standardized. Inguinal hernias
are common but incisional hernias also require clinical and surgical endeavor to manage her­nia related complications and clinical outcomes. Almeh et al. (2019) have studied asymptom­atic umbilical hernias in pediatric group [3]. In their systematic review, they have concluded that asymptomatic and uncomplicated umbilical her­nias may be conservatively managed till 4–5years of age. Prophylactic umbilical hernia repair may be considered after these ages, when overall risk is acceptable for surgery [27]. Gong etal. (2018) have recently reported that watchful waiting for asymptomatic or minimally symptomatic ingui­nal hernias may merely delay the need for surgery [2]. Thus, even in asymptomatic inguinal hernias, prophylactic hernia repair may be considered to prevent future inguinal hernia related intestinal obstruction and strangulation [28, 29]. Further guidance may be available from international guidelines for inguinal hernia management [30].
16 Prophylactic Surgery forSmall Intestines
175
16.3.1.2 Prophylactic Intestinal Resections
Meckel’s diverticulum (MD) is a congenital mal­formation and related with life-time risk of com­plications [31]. Most of MD remain incidental and may be related with gastrointestinal bleed­ing, intestinal obstruction, and inammation. However, preoperative diagnosis has limitations with imaging and requires laparotomy or lapa­roscopy. Complication related risk factors are reported to be gender (male), age (younger than
40), size of diverticulum (longer than 2cm), and
macroscopic mucosal alterations observed dur­ing surgery. Segmental resection and anastomo­sis are the recommended procedure to minimize residual heterotopic mucosa. McKay (2007) has reported results of 29 cases with MD in 2007. Ratio of symptomatic cases to asymptomatic cases was 9/20. Male to female ratio was 16/13. Symptomatic cases were signicantly younger than the asymptomatic cases (Mean ± SD ages were 34.9 ± 23.2 years compared with
64.2 ± 16.5, respectively). Twenty cases with
MD were treated with surgery and 10 of these cases were asymptomatic. Laparoscopic segmen­tal resections and diverticulectomies were per­formed and these surgical procedures were not comparable for postoperative complications and results. In addition, heterotopic mucosa was not observed in the asymptomatic MD cases [32].
Pariza etal. (2011) have reported their experi­ence with 62 MD cases [33]. Thirty MD cases were incidental; male gender and younger age were signicantly related with symptomatic and complications in their series. They have reported two cases of diverticulum tumor, an intussuscep­tion case, and a perforation case with unknown object. Post-diverticulectomy complications were not rare (1 in every 4 cases have been reported to have complications) and suppuration was the most common. Blouhos et al. (2018) have reviewed surgical concerns on MD in adults in 2018 [34]. They have not recommended rou­tine resection in asymptomatic MD cases and listed some risk factors for developing future complications to be considered before surgery These risk factors included patient age (younger than 50 years), gender (male), diverticulum
length (longer than 2cm), and presence of ecto­pic or abnormal features within the diverticulum. They have recommended diverticulectomy for long and wedge resection for short MD.Mora­Guzman etal. (2018) have updated their series in 2018 with 66 cases [35]. In this recent report, they have observed three cases of neuroendocrine tumors. To summarize, male and young patients (younger than 40 age) with incidental MD may be considered for routine prophylactic segmental resection. For all cases with incidental MD between 40 and 50years of age, prophylactic sur­gery should be considered on case by case condi­tions and risk factors. There is no specic need of prophylactic surgery for female gender with inci­dental MD.However, for all cases with incidental MD patients older than 50 should not be consid­ered for routine prophylactic surgery for inciden­tal MD.
16.3.1.3 Endoscopic or Surgical Drainage
Small intestinal duplication cysts are rare clinical entities and are commonly observed in jejunum and ileum. Duodenal duplication cysts are rela­tively observed less frequently [36]. Duplication cysts are located on the mesenteric side of gas­trointestinal tract but have no luminal openings. These cysts may contain any heterotopic mucosa and have a muscular wall, with the same vascular supply with the intestinal segment, which the cysts have been adjacently located [37, 38]. Duodenal duplication cysts are commonly located in the second and the third portion of the duodenum and may be related with pancreaticobiliary system [11,
36]. Gastrointestinal duplication cysts are develop-
mental abnormalities, and common in the newborn and early childhood. However, cases after twenties have been reported. There is no male or female selection in demographic features [11]. Clinically small intestinal duplication cysts may present with mild symptoms and may be dened with imaging studies. However, gastrointestinal bleeding, intes­tinal or biliary obstruction, and pancreatitis may complicate the clinical course [39]. Heterotopic mucosa was previously mentioned, and carcinoids or adenocarcinoma has been related to duode­nal duplication cysts [40, 41]. A small intestinal
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F. Yaylak and M. Özsoy
duplication cyst with symptoms or complications merits a surgical intervention. Minimal invasive surgery with endoscopy or laparoscopy may be considered, and the prognosis is expected to be fair [36]. With the use of computed tomography and ultrasound may catch a small intestinal duplication cyst [42]. In such situation a prophylactic surgery may be rational approach, rather than watch and wait. Simple drainage, total or partial cystectomy, cyst fenestration or resections may be considered on case by case basis accordingly [43].
16.3.1.4 Endoscopic or Surgical Polypectomy
Small intestinal polyps or polyposis may not be common, but duodenum is the primary site. Gaspar et al. (2016) have outlined endoscopic interven­tions for both benign and precancerous duodenal lesions [44]. Endoscopic or surgical interventions may be indicated or considered during a surveil­lance of a patient with polyposis [13, 14].
16.3.1.5 Closure ofOmental or Mesenteric Openings
After a major abdominal surgery which includes a gastric resection, a pancreaticoduodenectomy or a transvers colon resection, or during gastric bypass surgery a potential defect in gastrocolic ligament, omentum, or mesentery has been created. A poten­tial intraperitoneal defect is known to be related with internal herniation, small intestinal obstruc­tion, and strangulation [15, 16]. Thus, whenever an internal defect is created a prophylactic closure should be performed to minimize the risk of inter­nal herniation related complications.
16.3.2 Secondary Prophylactic
Surgeries withSmall Intestines
16.3.2.1 Prophylactic Stoma
Formations withSmall Intestine
Total colectomy with ileorectal anastomosis or total proctocolectomy with ileoanal anastomosis is per­formed to treat colorectal polyposis or inamma­tory bowel disease. To prevent ileorectal or ileoanal
anastomosis, a proximal stoma formation with tem­porary ileostomy may be constructed. In such cases, primary intentions will be to decompress distal anas­tomosis, to minimize anastomotic leakage, and to decrease ileorectal or ileoanal stula rates and intra­pelvic or intra-abdominal sepsis. Recently, Güenaga etal. (2008) have reviewed ve randomized clinical trials for temporary use of ileostomy or colostomy (68 and 166in each group, respectively) for colorec­tal anastomosis [ “mortality, wound infection, time of stoma forma­tion, time of stoma closure, time interval between stoma formation and closure, stoma prolapse, stoma retraction, parastomal hernia, parastomal stula, ste­nosis, necrosis, skin irritation, ileus, bowel leakage, reoperation, patient adaptation, length of hospital stay, colorectal anastomotic dehiscence, incisional hernia, and postoperative bowel obstruction.” They have concluded that only stoma prolapse was signif­icant. For practical reasons, prophylactic ileostomy may be considered after a colorectal anastomosis formation. However, Gavriilidis et al. (2019) have concluded that an ileostomy is not favored when stoma formation and closure related complications have been considered [ have suggested decreases morbidity rates with loop ileostomy after anterior resection in the expense of dehydration risk [47]. In this study, 666 LI and 397 LC were compared, a data which may reect the surgical practice.
45]. The primary end points were
46]. Chudner et al. (2019)
16.3.2.2 Feeding Jejunostomy
Nutritional supplement may be essential after a major abdominal surgery. Whenever possible oral or enteral route is preferred. A temporary supplement may be required to oral intake with a feeding jejunostomy [2123]. Esophagus and gastric cancers are known to deplete the patient nutritionally. After restoration of gastrointes­tinal continuity, it may take time to begin oral intake, or additional supplement may be needed. Feeding jejunostomy may be constructed during the initial surgery or an endoscopic placement of feeding catheter may be the other option.
16.3.2.3 Permanent Access forERCP
Hepaticojejunostomy may be performed after a biliary resection for benign or malign disorders
16 Prophylactic Surgery forSmall Intestines
177
such as strictures, extrahepatic biliary lesions, or periampullary mass. Reconstruction of hepati­cojejunostomy may limit the access to biliary tract through the upper gastrointestinal tract. Thus, a formation of a permanent access has been reported to help in such conditions to bili­ary tract. This access is achieved with subcuta­neous blind isolated loop of jejunum, which is constructed after a Roux-Y hepaticojejunostomy [24, 25]. There is limited data for the outcomes, but when a route to biliary tract through upper gastrointestinal tract with an endoscope, this pro­cedure may be considered.
16.3.3 Intestinal
Auto-Transplantation
Small intestinal transplantation has not been reported previously as a prophylactic surgery. It will not be a routine, but to outline the ratio­nale of prophylactic surgery a case of intesti­nal auto- transplantation will be discussed in this section. Cheng et al. (2018) have recently reported an exvivo resection and intestinal auto­transplantation [26]. The procedure was required for a desmoid tumor removal in a patient with familial polyposis. In this case, resection was complicated due to vascular involvement. However, a preemptive resection of the supe­rior mesenteric artery shed area was planned. Surgery was completed with resection, and auto­transplantation was performed with jejunostomy. As to say, prophylaxis may sometime require do more now rather than tomorrow, and another sometime do less now, and wait.
16.4 Role ofMinimal Access or
Invasive Surgery inProphylactic Surgery ofSmall Intestines
Abdominal surgery is a major risk factor for the development of postoperative ileus, obstruction development, and abdominal wall hernias [48]. However, minimal access or invasive surgery tech­niques may be indicated, accessible, and consid-
erable whenever possible. Some examples may include a percutaneous drainage of an abdominal cyst or abscess with ultrasonography guidance, which may exclude an abdominal surgery com­pletely [49]. Using laparoscopy or robotics to resect a colorectal cancer has clear advantageous over open surgery to minimize surgical complications which may affect small intestines [50]. Endoscopic removal of precancerous polyps or endoscopic mucosal resections of early gastrointestinal can­cers may have the same effects to minimize risk of abdominal surgeries [51]. This section has out­lined the need of the consideration of the surgical technology as a mean of prophylactic approach to prevent small intestinal anatomical and functional integrity. We the authors strongly recommend a minimal access or invasive surgery, whenever feasible and accessible for abdominal procedures. This approach may prevent small intestines from surgical complications such as intra-abdominal adhesions or abdominal wall hernias and related intestinal complications mainly intestinal obstruc­tions, strangulations, and intestinal resections.
16.5 Conclusion
Prophylactic surgery of small intestines is primar­ily needed whenever a clear risk of anatomic or functional loss of small intestine. This risk may arise from an inammation which may cause bleeding, obstruction, and perforation. These conditions may require advanced and emergent interventions such as further intestinal resec­tions related with severe intestinal insufciency. Even fatality may occur. In some certain clinical precancerous lesions, prophylactic resection of lesion may be considered.
Small intestinal surgeries may be needed with the intent of other prophylactic aims or rationales. In these conditions, the aim or rationale of small intestinal surgical procedures is not related to pre­vent small intestinal functions or anatomical integ­rity. These procedures include loop ileostomy to decompress a distal anastomosis, a preemptive feeding jejunostomy after a major abdominal sur­gery, a construction of a blind subcutaneous jejunal loop to access a biliary anastomosis.
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F. Yaylak and M. Özsoy
Prophylactic small intestinal surgeries may be performed with endoscopic, laparoscopic (even with robotic), or open surgical techniques. Hernia repair, resections, construction of a stoma, lysis of adhesion, and even an auto-transplantation may be indicated or considered as a prophylactic procedure. Minimal access or invasive surgery may minimize future intestinal adhesions which are known with risk of intestinal obstructions.
References
1. Berger D.Evidence-based hernia treatment in adults.
Dtsch Arztebl Int. 2016;113(9):150–8.
2. Gong W, Li J. Operation versus watchful waiting in
asymptomatic or minimally symptomatic inguinal
hernias: the meta-analysis results of randomized con-
trolled trials. Int J Surg. 2018;52:120–5.
3. Almeh W, AlRaymoony A, AlDaaja MM, Abdullah
B, Oudeh A.A systematic review of current consensus
on timing of operative repair versus spontaneous clo-
sure for asymptomatic umbilical hernias in pediatric.
Med Arch. 2019;73(4):268–71.
4. Hansen CC, Søreide K.Systematic review of epide-
miology, presentation, and management of Meckel’s
diverticulum in the 21st century. Medicine (Baltimore).
2018;97(35):e12154.
5. van Malderen K, Vijayvargiya P, Camilleri M, Larson
DW, Cima R.Malignancy and Meckel’s diverticulum:
a systematic literature review and 14-year experience
at a tertiary referral center. United Eur Gastroenterol J.
2018;6(5):739–47.
6. Kuru S, Kismet K. Meckel’s diverticulum: clinical
features, diagnosis and management. Rev Esp Enferm
Dig. 2018;110(11):726–32.
7. Kotha VK, Khandelwal A, Saboo SS, Shanbhogue
AKP, Virmani V, Marginean EC, et al. Radiologist’s perspective for the Meckel’s diverticulum and its com­plications. Br J Radiol. 2014;87(1037):20130743.
8. Kabir SA, Raza SA, Kabir SI.Malignant neoplasms
of Meckel's diverticulum; an evidence based review. Ann Med Surg (Lond). 2019;43:75–81. Published 2019 Jun 4.
9. An J, Zabbo CP.Meckel diverticulum. In: StatPearls.
Treasure Island, FL: StatPearls; 2020.
10. Caracappa D, Gullà N, Lombardo F, Burini G,
Castellani E, Boselli C, et al. Incidental nding of carcinoid tumor on Meckel's diverticulum: case report and literature review, should prophylactic resection be recommended? World J Surg Oncol. 2014;12:144. Published 2014 May 8.
11. Tsai SD, Sopha SC, Fishman EK.Isolated duodenal
duplication cyst presenting as a complex solid and cystic mass in the upper abdomen. J Radiol Case Rep. 2013;7(11):32–7.
12. Blank G, Königsrainer A, Sipos B, Ladurner R.Adenocarcinoma arising in a cystic duplication of the small bowel: case report and review of literature. World J Surg Oncol. 2012;10:55.
13. McGarrity TJ, Amos CI, Baker MJ.Peutz-Jeghers syn­drome. In: Adam MP, Ardinger HH, Pagon RA, etal., editors. GeneReviews®. Seattle, WA: University of Washington, Seattle; 1993.
14. Larsen Haidle J, Howe JR.Juvenile polyposis syn­drome. In: Adam MP, Ardinger HH, Pagon RA, etal., editors. GeneReviews®. Seattle, WA: University of Washington, Seattle; 1993.
15. Stenberg E, Szabo E, Ottosson J, Thorell A, Näslund I. Health-related quality-of-life after laparoscopic gastric bypass surgery with or without closure of the mesenteric defects: a post-hoc analysis of data from a randomized clinical trial. Obes Surg. 2018;28(1):31–6.
16. Mala T, Kristinsson J.Akutt inneklemming av tarm etter gastrisk bypass for sykelig fedme [Acute internal hernia following gastric bypass for morbid obesity]. Tidsskr Nor Laegeforen. 2013;133(6):640–4.
17. Beyer-Berjot L, Baumstarck K, Loubière S, Vicaut E, Berdah SV, Beonist S, et al. Is diverting loop ileos­tomy necessary for completion proctectomy with ileal pouch-anal anastomosis? A multicenter randomized trial of the GETAID Chirurgie group (IDEAL trial): rationale and design (NCT03872271). BMC Surg. 2019;19(1):192.
18. Pisano M, Zorcolo L, Merli C, Cimbanassi S, Poiasina E, Ceresoli M, etal. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perfo­ration. World J Emerg Surg. 2018;13:36.
19. Plasencia A, Bahna H.Diverting Ostomy: for whom, when, what, where, and why. Clin Colon Rectal Surg. 2019;32(3):171–5.
20. Rajaretnam N, Lieske B.Ileostomy. In: StatPearls. Treasure Island, FL: StatPearls; 2020.
21. Brett K, Argáez C.Gastrostomy versus gastrojejunos­tomy and/or jejunostomy feeding tubes: a review of clinical effectiveness, cost-effectiveness and guide­lines. Ottawa, ON: Canadian Agency for Drugs and Technologies in Health; 2018.
22. Berkelmans GH, van Workum F, Weijs TJ, Nieuwenhuijzen GA, Ruurda JP, Kouwenhowen EA, et al. The feeding route after esophagectomy: a review of literature. J Thorac Dis. 2017;9(Suppl
8):S785–91.
23. Baker ML, Halliday V, Robinson P, Smith K, Bowrey DJ.Nutrient intake and contribution of home enteral nutrition to meeting nutritional requirements after oesophagectomy and total gastrectomy. Eur J Clin Nutr. 2017;71(9):1121–8.
24. Sachse RE, Hutson DG, Russell E, Levi JJ, Schiff E.Die Hepaticojejunostomie mit subcutanem blindem jejunumsegment. Eine alternative in der behandlung stenosierender gallengangserkrankungen [hepatico­jejunostomy with a subcutaneous blind jejunum seg­ment. An alternative in the treatment of stenosing bile duct diseases]. Chirurg. 1990;61(5):402–6.
16 Prophylactic Surgery forSmall Intestines
179
25. Oruğ T, Oymaci E, Neşşar G, Atalay F.Blind subcu­taneous jejunal loop for interventional procedures in recurrent benign biliary stricture. Ulus Cerrahi Derg. 2007;23(2):65–6.
26. Cheng C, Guo S, Kollie DEGB, Zhang W, Xiao J, Liu L, et al. Ex vivo resection and intestinal auto­transplantation for a large mesenteric desmoid tumor secondary to familial adenomatous polyposis: a case report and literature review. Medicine (Baltimore). 2018;97(20):e10762.
27. Kulaçoğlu H. Current options in umbilical her­nia repair in adult patients. Ulus Cerrahi Derg. 2015;31(3):157–61.
28. Wu CC, Chueh SC, Tsai YC.Is contralateral explora­tion justied in endoscopic total extraperitoneal repair of clinical unilateral groin hernias—a prospective cohort study. Int J Surg. 2016;36(Pt A):206–11.
29. Berndsen MR, Gudbjartsson T, Berndsen FH.Inguinal hernia—review. Laeknabladid. 2019;105(9):385–91.
30. HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018;22(1):1–165.
31. Mora-Guzmán I, Muñoz de Nova JL.Meckel’s diver­ticulum in the adult: prophylactic surgery. J Visc Surg. 2018;155(2):167.
32. McKay R. High incidence of symptomatic Meckel’s diverticulum in patients less than fty years of age: an indication for resection. Am Surg. 2007;73(12):1293.
33. Pariza G, Mavrodin CI, Sajin M, Ciurea M.Surgical management of Meckel's diverticulum in adults— retrospective analyses of 62 cases. Chirurgia. 2011;106(1):45–9.
34. Blouhos K, Boulas KA, Tsalis K, Barettas N, Paraskeva A, Kariotis I, etal. A Meckel’s diverticulum in adults: surgical concerns. Front Surg. 2018;5:55.
35. Mora-Guzmán I, Muñoz de Nova JL, Martín-Pérez E.Meckel’s diverticulum in the adult: surgical treat­ment. Acta Chir Belg. 2018;27:1–5.
36. Seeliger B, Piardi T, Marzano E, Mutter D, Marescaux J, Pessaux P. Duodenal duplication cyst: a potentially malignant disease. Ann Surg Oncol. 2012;19(12):3753–4.
37. Chen JJ, Lee HC, Yeung CY, etal. Meta-analysis: the clinical features of the duodenal duplication cyst. J Pediatr Surg. 2010;45:1598–606.
38. Macpherson RI. Gastrointestinal tract duplications: clinical, pathologic, etiologic, and radiologic consid­erations. Radiographics. 1993;13(5):1063–80.
39. Meier AH, Mellinger JD. Endoscopic manage­ment of a duodenal duplication cyst. J Pediatr Surg. 2012;47:33–E35.
40. Falk GL, Young CY, Parer J.Adenocarcinoma arising in a duodenal duplication cyst: a case report. Aust N Z J Surg. 1991;61:551–3.
41. Inoue M, Nishimura O, Andachi H, Koga S. Early cancer of duodenal duplication a case report. Gastroenterol Jpn. 1979;14(3):233–7.
42. Bowen B, Ros PR, McCarthy MJ, Olmsted WW, Hjerstad BM.Gastrointestinal teratomas: CT and US appearance with pathologic correlation. Radiology. 1987;162(2):431–3.
43. Gjeorgjievski M, Manickam P, Ghaith G, Cappell MS. Safety and efcacy of endoscopic therapy for nonmalignant duodenal duplication cysts: case report and comprehensive review of 28 cases reported in the literature. Medicine (Baltimore). 2016;95(22): e3799.
44. Gaspar JP, Stelow EB, Wang AY. Approach to the endoscopic resection of duodenal lesions. World J Gastroenterol. 2016;22(2):600–17.
45. Güenaga KF, Lustosa SA, Saad SS, Saconato H, Matos D. Ileostomy, or colostomy for temporary decompression of colorectal anastomosis. Systematic review and meta-analysis. Acta Cir Bras. 2008;23(3): 294–303.
46. Gavriilidis P, Azoulay D, Taampas P.Loop transverse colostomy versus loop ileostomy for defunctioning of colorectal anastomosis: a systematic review, updated conventional meta-analysis, and cumulative meta­analysis. Surg Today. 2019;49(2):108–17.
47. Chudner A, Gachabayov M, Dyatlov A, Lee H, Essani R, Bergamaschi R. The inuence of diverting loop ileostomy vs. colostomy on postoperative morbid­ity in restorative anterior resection for rectal cancer: a systematic review and meta-analysis. Langenbecks Arch Surg. 2019;404(2):129–39.
48. ten Broek RP, Issa Y, van Santbrink EJ, Bouvy ND, Kruitwagen Roy FPM, etal. Burden of adhesions in abdominal and pelvic surgery: systematic review and meta-analysis. BMJ. 2013;347:f5588.
49. Huang DY, Yusuf GT, Daneshi M, Ramnarine R, Deganello A, Sellars ME, etal. Contrast-enhanced ultrasound (CEUS) in abdominal intervention. Abdom Radiol (NY). 2018;43(4):960–76.
50. Solaini L, Bazzocchi F, Cavaliere D, Avanzolini A, Cucchetti A, Ercolani G.Robotic versus laparoscopic right colectomy: an updated systematic review and meta-analysis. Surg Endosc. 2018;32(3):1104–10.
51. Ochiai Y, Kato M, Kiguchi Y, Akimoto T, Nakayama A, Sasaki M, et al. Current status and challenges of endoscopic treatments for duodenal tumors. Digestion. 2019;99(1):21–6.
Prophylactic Appendectomy
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OsmanNuriDilek , HaldunKar , andTuranAcar
17
17.1 Introduction
Appendectomy is one of the most performed abdominal operations. It is an operation per­formed for 285 years since Claudius Amyand performed the rst appendectomy in 1735. The frequency of appendectomy has been reported between 75–135/100,000 per year [1]. It is reported that the rate of appendicitis diagnosis has increased by 0.5/100,000 annually since 1995 [1, 2]. The incidence of appendicitis may differ according to age, sex, race, and socioeco­nomic status. It is slightly more common in men, and the male/female ratio has been reported as
1.08 [1]. The diagnosis of appendicitis varies periodically and is most often made in the third quarter of the year in the summer [1]. The accu­racy of the diagnosis of appendicitis varies depending on gender, and the correct rate of diag­nosis in women (78.6%) is lower than the rate of
O. N. Dilek (*) Department of Surgery, Section of Hepatopancreatobiliary Surgery, Izmir Kâtip Çelebi University School of Medicine, İzmir, Turkey e-mail: osmannuri.dilek@ikc.edu.tr
H. Kar Department of Surgery, IKÇÜ, Atatürk Education and Research Hospital, Izmir, Turkey e-mail:
haldun.kar@saglik.com.tr
T. Acar Department of Surgery, School of Medicine, Izmir Katip Celebi University, Izmir, Turkey e-mail: turan.acar@ikc.edu.tr
correct diagnosis in men (91.2%) [3]. An epide­miological study conducted in South Korea cal­culated that 16% of people were diagnosed with appendicitis at some point in their lives, and
59.7% of whom underwent appendectomy. It has
also been stated that the reason for the appendec­tomy rate in South Korea to be higher than west­ern societies may be due to the National Life Insurance, whose scope has been extended in recent years [1].
Appendicitis was found most frequently in the 10–14 age group in males and the 15–19 age group (169/100,000) in females, while it was the least (36/100,000) in the group under 5 [1, 2]. In 75–79 age group, in which appendicitis is also common, complications have been encountered more frequently.
In the literature, peaking in 10–19 and 74–79 age groups is dened as an M-shaped pattern [1,
4, 5]. Anderson etal. (2012) reported that the fre-
quency of lifetime appendicitis varies with age [2]. According to this study, it was calculated as
3.2% in 20 age group, 5.5% in 40 age group,
7.2% in 60 age group, and 9% in group above 85years old [2]. In America, the rates are differ­ent, and 12% of men and 23% of women have been found to have an appendectomy. Whites and Hispanics were diagnosed with appendicitis more, while those with African and Asian origins were diagnosed less. Also, the rate of diagnosis of appendicitis was higher, and the rate of perfo­rated appendicitis was lower in those with com­prehensive health insurance [2, 3, 6]. It is also
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2021 O. N. Dilek et al. (eds.), Prophylactic Surgery, https://doi.org/10.1007/978-3-030-66853-2_17
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known that the risk of appendicitis is lower in communities fed a ber-rich diet [1, 7].
In the literature, 20–30% of cases in appendi­citis series are perforated appendicitis, and in epidemiological studies, the incidence of perfo­rated appendicitis was found to be 29/100,000 [1, 2]. The risk of perforation is slightly less in women. The perforation risk is higher in the old­est (85 age) and youngest (0–4 age) patient group. Perforation was detected in 15.4% of the cases in the 15–19 age group and 52–55% of the patients over 85years old [1]. Interestingly, it was found that perforation was more common in Hispanics and Asians and people without private insurance [2]. The period with the highest fre­quency of perforation was determined as winter months (December). The rate of cases with per­forated appendicitis detected in a particular hos­pital has decreased over time due to increased teamwork [2].
17.2 Approach toAppendix
Problems
17.2.1 Nonsurgical Approach
forAppendicitis
There are some clinical studies on the medical treatment of appendicitis. Studies are stating that up to 90% of successful answers have been obtained with antibiotic treatment, especially in appendicitis series selected without complica­tions [8, 9]. Hansson etal. (2009) reported that antibiotic therapy was successful in 92.2% of cases with antibiotic therapy in their series of unselected patients. However, 13.9% of cases developed recurrent appendicitis, and major complications were seen three times more in the appendectomy group [10]. In general, the prefer­ence of surgeons for appendicitis still favors appendectomy.
17.2.2 Protection oftheAppendix
Some authors think that the protection of the appendix will be benecial. “Appendiceal con-
duits” can be used in the treatment of some uro­logical, neurological, and biliary pathologies. The appendix has been used for the purpose of eliminating fecal incontinence in Spina bida, Hirschsprung’s disease, imperforate anus, and some neurological diseases (MACE procedure), for biliary reconstruction in choledochal cysts, and appendico-vesicostomies (Mitrofanoff pro­cedure) [11]. In the literature, such studies are very few and usually in the form of a case report. However, the use of the appendix for reconstruc­tion has diminished due to the development of surgical and minimally invasive techniques. However, some suggest that the appendix be pre­served due to the possibility of using it for “tubu­lar conduit” in the future [12].
17.3 Appendectomies
The appendectomy procedure is simple and tech­nically well-standardized surgery. Appendectomy is performed during many procedures without questioning whether there is an infection/pathol­ogy. In the last 20years, the appendectomy rate has started to increase with the laparoscopic approach due to less pain, more comfort, shorter hospitalization, shorter postoperative ileus, and low risk of infection, and today 74.6% of cases are performed laparoscopically. This rate is slightly lower (63.3%) in perforated appendicitis [2, 13, 14].
There is no consensus about the normal appen­dix in laparotomies. Especially in cases of endo­luminal appendicitis, it becomes more challenging to diagnose. Some authors suggest performing an appendectomy, even if the appendix is normal­looking, in the lower right quadrant pain, the rea­son for which cannot be understood [2, 13, 15]. On the other hand, most of the authors recom­mend performing prophylactic appendectomies before 30years of age [14].
Appendectomies, which are the valid treat­ment in the treatment of acute appendicitis in the clinic, have also clinical applications in the form of prophylactic, incidental, and interval appen­dectomy (Table17.1). All three applications are for prophylactic purposes.
17 Prophylactic Appendectomy
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Table 17.1 Classication of etiologic factors for prophylactic appendectomy
Prophylactic appendectomy Incidental appendectomy
• Appendiceal masses • Metal intoxication (Hg) • Mesenteric
• Diveticular disease • FMF • Urinary diversion • Bariatric surgery
• Space travel • Fecalith
• Pole travel • Plastrone (interval) • Crohn’s disease • Negative laparotomy
• Foreign bodies • Radical cystectomy • Amyand hernia
• Parasites • Baryum meal • Ovarian pathologies • Cesarean
FMF Familial mediteranean fever, VP ventriculoperitoneal, Hg Mercury
(Appendicolith)
Malrotations • Intussusception
• Chronic pelvic pain • Cystic brosis
• Right colon diverticula • VP shunts for hydrocephalus
Endometriosis
lymphadenitis
• Omental tortion/ infarction
• Cytoreductive surgery • Incisional hernia repair
• Emergency sigmoidectomy
• Abdominal cocoon syndrome
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17.3.1 Incidental Appendectomy
Incidental appendectomy (IA) can be dened as adding an appendectomy to the procedure while performing another surgery. It is performed to prevent appendicitis complications, probable dif­culties in differential diagnosis, and a second surgery in the future. The current incision is used for appendectomy [14]. In 1902, Kelly surveyed 80 well-known surgeons on the IA.Thirty seven percent of surgeons reported that they routinely perform IA, and 72% reported that they per­formed an appendectomy if the appendix was attached to the surrounding tissues [3, 16]. Kelly, who opposes IA, published this survey and its results in JAMA in 1902, as the function of the appendix is not yet known and will increase sur­gical morbidity. Appendectomy for reasons other than appendicitis has been discussed in the litera­ture for a long time. Inversion appendectomy, dened in 1895 and popularized in the 1960s for a short time, aimed to reduce the risk of infection and congestion. It was abandoned due to impaired blood supply of the appendix and increased risk of necrosis and intussusception. However, some series reporting that PA performed by the invagi­nation method during cesarean does not nega­tively affect mortality and morbidity [17]. The interval appendectomy is another form of PA, which is performed in months after the regression of plastron appendicitis. Interestingly, 69% of patients undergoing appendectomy for acute
appendicitis are under 30 years of age, while 75% of patients performed IA are over 25years of age [3, 18].
Snyder etal. (1998) reported the lifetime IA rate as 2.9% in men and 16% in women. In male patients, 36.6% of cases were reported to be per­formed during cholecystectomies, 11.8% of bowel resections, and 4.9% during hernia opera­tions [3]. In female patients, 45% of incidental appendectomies were performed during hyster­ectomies, 37.5% during salpingo-oophorectomy,
18.4% during cholecystectomy, and 7.2% during oophorectomy. IA is performed more (6–12 times) during gynecological operations, espe­cially of women of reproductive age [3]. They recommended to add appendectomy to women under 35years of age during gynecological inter­ventions. There is no consensus in 35–50years old patients due to the risks associated with appendectomy (bleeding, infection, ileus, increased morbidity rates). It is not generally rec­ommended over the age of 50 [3]. As the gyneco­logical surgeries started to be performed more laparoscopically, incidental appendectomies were also started to be performed more. In com­mon gynecological pathologies such as endome­triosis, ovarian cyst torsions, and cyst ruptures, the laparoscopic approach is preferred and many gynecologists add IA to the procedure. Apart from these, the appendix was also removed dur­ing laparotomies for different reasons (Table17.1).
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Appendectomy is frequently added to the pro­cedure in cases where laparoscopy is performed to determine the chronic pelvic pain etiology. On the other hand, the probability of negative appen­dectomy increases 2.5 times in women of child­bearing age due to pelvic pathologies [3, 18]. Different results have been reported in the evalu­ation of the specimens whose histopathological examination was performed to clarify the etiol­ogy of pelvic pain. Krone etal. (1989) reported that 1718 (32%) appendectomy performed in the series of 5369 gynecologic laparotomy cases. In the histopathological evaluation of appendec­tomy specimens, appendix was found to be mor­phologically normal in 368 (21.4%) cases, acute appendicitis in 136 (7.9%) cases, and chronic appendicitis in 1118 (65.1%) cases, and carci­noid, mucocele and endometriosis in 96 (5.6%) cases [19].
Endometriosis syndromes also play an impor­tant role in the etiology of chronic pelvic pain. The coexistence of endometriosis in the appendix varies according to the selected patient group. Although endometriosis is rare (0.2%) in patients with acute appendicitis, the frequency of endo­metriosis varies between 9.3% and 39% in the appendix of patients with endometriosis syn­drome. The rate of endometriosis in the appendix
of patients with reproductive pelvic pain has been reported as 8.5% [18]. Appendix pathology is detected in 30.2–59.0% of patients in this group. Interestingly, the incidence of carcinoid tumors in the appendix in the population was 0.3–1.0%, while this rate was reported as 2.3–4.2% in women of reproductive age [20]. In cases of deep inltrative endometriosis (DIE), the risk of endo­metriosis in the appendix is further increased (15.5–39.0%) [21]. IA to be performed in these patients may have an important contribution in eliminating possible appendix pathologies and pelvic pain. Lynch et al. (1997) reported that pel­vic pain resolved in 117 (90%) of 130 cases they performed appendectomy for pelvic pain [22]. Appendectomy can be performed synchronously during the gynecological intervention as well as prophylactically in cases with subsequent diag­nosis of endometriosis [18]. As a result, in one of 10 patients with endometriosis, one in 4 patients with DIE, IA disease will be a preventive procedure.
There are many publications stating that appendectomy has been added to the process dur­ing malrotations (Fig.17.1), atresia, intussuscep- tion, ovarian torsion, mesenteric lymphadenitis, incisional hernia repair, and colon resections [13,
23]. In patients undergoing Ladd’s procedure due
a
Fig. 17.1 This picture (a) shows the case in which we underwent an appendectomy (arrow) from the left thoracotomy (b) in a patient with intestinal malrotation and Bochdalek hernia. S spleen, C caecum (Archive of ON Dilek)
b
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