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462 Index
https://t.me/medicina_free
cutaneous vasculitis, 114, 115 cyclophosphamide, 128 cyclosporine, 112 cytokines, 383
D
Dahlgren and Whitehead’s
model, 319 Darco healing sandal, 212, 213 debulking surgery, 82, 83 decongestive therapy, complete, 86 deep femoral artery, 29 deep femoral artery, 29, 29 deep vein, 15
on plantar surface of foot, 193 valve incompetence in, 18
deep vein thrombosis (DVT), 20, 25,
68–69, 158, 190, 228, 355, 385 deep venous systems, 14 dehydration, 253 dendritic cells, 28 dermatitis artefacta, 168
diagnosis, 170 examination, 169 history, 168–169 intervention, 170–172 investigations, 170 leg wounds due to self‐harm, 169
self‐harm rescue pack, 172 dermatology, 165, 306 dermoscopy, 153 diabetes mellitus, 31, 253, 268
blood tests for, 136
diabetes/associated peripheral
neuropathy, 229
disease process of, 138 diet, 438, 442
ketogenic or anti‐inammatory, 96
and nutritional status, 58, 232 disease‐modifying anti‐rheumatic
drugs (DMARDs), 118, 122 disease pathology, 23, 132, 303 Doppler ABPI reassessment, 276
Doppler ultrasound, 164, 265 dorsalis pedis artery, 270, 271–272 dressing(s), 1, 4, 112–113,
231–232, 286, 372 access to, 8 adhesive, 122 antimicrobial, 155 change, 295, 299, 303, 305, 307 charcoal, 155 choice, 129 electrode, 141 foam, 7 management of, 3 metronidazole gel, 155 prescription costs, 3 primary, 122, 154 product analysis, 6–7 product classication, 4–6, 5 secondary, 122, 154 selection, 171 topical antimicrobial, 122
dressing optimisation scheme/
system (DOS), 6–8
drug‐induced leg ulcers, 155.
Seealso Martorell’s ulcers cutaneous atypical wounds, 156 leg ulceration in people who
inject drugs, 157–161 medication‐related
ulceration, 155–157
E
early intervention, 84, 227,
266, 344, 360
ecthyma, 172, 173 ecthyma gangrenosum, 173, 174 eczema, 75 elastic arteries, 28 elastic bandage, 358, 358 elastic bandage, static stiness
for, 380, 380
electrode dressing, 141 electrostimulation, 141
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Index 463
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embolism, 32 emollients, 74, 76, 431–434 emotional responses, 290 endothelium, 11, 20, 21, 28,
37, 44, 131 endovenous ablation, 354, 411, 412 end‐stage renal failure
(ESRF), 141, 142 epithelisation, 38 erosive pustular dermatosis
(EPD), 161
compression therapy, 166 dermatitis artefacta, 168–172 diagnosis, 164 dierential diagnoses of, 162 examination, 162–163 intervention, 164 investigations, 163–164 local wound care, 165 oral treatments, 165 patient self‐care, 166–168 pustules and crusted areas to
surrounding skin, 163
self‐management, 167–168 topical treatments, 165
erythrocyte sedimentation rate
(ESR), 73, 117 Escherichia coli, 173 European standard hosiery,
416, 417 European Wound Management
Association (EWMA), 153 evidence‐based clinical
management, 318 evidence‐based practice, 330, 444 excoriation, 264, 367 exercise, 86
mobility and, 209 seated ankle joint exercises with
TheraBand, 210 extrinsic age, 253 exudate management, 130, 154, 234,
366, 369–371, 371372
F
fabric aid, 429 factitious ulcers. See dermatitis
artefacta
fall(ing)
mechanisms, 201 reasons for, 202 reducing falls risk, 216 screening and assessment
of, 216, 217
screening tools for, 217 family/carer support, 234 fan strapping techniques, 396 fat, 32, 35, 87
cells, 87
lipoedema, 95
non‐lipoedema, 95
pads, 87, 91 femoral artery, 29, 29 brin cu theory, 21, 22 broblasts, 28, 37, 38 brosis, 51, 61, 64, 77, 86,
123, 128, 366 Five Year Forward View, 441 at‐knit garments, 417–418 foam dressings, 6, 7 foot:
arterial pulses of, 271 compression of, 396–397 deformities, 119–120, 120 pump, 17, 17, 193–194
foot issues and mobility, 209
advice and education, 214–215 bespoke or semi‐bespoke footwear
and modications, 214
t and condition of footwear, 212 footwear, 211–212 temporary footwear, 212–214 walking and, 210–211
foot muscle pump (CMP), 189, 194
dysfunction, 190–191, 195–196 failure, 375
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464 Index
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foot orthoses (FO), 206, 215–216
fully custom‐made
functional, 214 o‐the‐shelf functional, 214 visco‐elastic, 216
foot ulceration, medications
causing, 362–364
footwear, 211–212
advice and education, 214–215 bespoke or semi‐bespoke
footwear, 214 t and condition of, 212 modications, 214 temporary, 212–214 tips on selection, 213
footwear, temporary, 212–214 front‐line healthcare practitioners, 2 fungating wounds, 145
G
gabapentin, 114, 145 gait cycle, 193, 205, 206, 207 gait disorders, 208 gate theory, 288–289, 289 Genu valgum, 96 German standard hosiery, 416, 417 giant cell arteritis, 115 goniometer, 196–197, 197 graduated compression therapy,
373, 381, 386
granulomatosis with
polyarteritis, 115
Group A Streptococcus
(GAS), 73, 160
H
haematological disorders, 230 haematology, 106, 133 haemophilia, 230 haemorrhoids, 229 haemostasis, 27, 36 ‘hammocking’ eect, 396 handheld Doppler, 267
calculation and interpretation of
ABPI, 273–276
measuring ankle systolic
pressure, 270–273
measuring brachial systolic blood
pressure, 269–270
performing procedure, 268 Hansen disease, 172, 175 Hashimoto disease, 88 healthcare professionals
(HCPs), 107, 435 healthcare resources, data for, 3 heart failure, 52, 230–231
acute deteriorating, 374 chronic, 84, 374, 385 compression in, 386
diuretic medications, 366 heparin, 156 History, Examination,
Investigations, Diagnosis, Interventions framework (HEIDI framework), 107
holistic lower limb
assessment, 190, 226 holistic reassessment, 409–411, 410 hosiery, 77. See also
compression hosiery
bespoke, 407, 421 British standard, 416, 417 care, 431 European standard, 416, 417 German standard, 416, 417 made‐to‐measure, 421 o‐the‐shelf, 422 patient education in
understanding, 429–431
self‐care in, 429–431 hydroxycarbamide, 156, 363–364 hydroxycarbamide‐induced
ulceration, 363 hydroxyurea. See hydroxycarbamide hyperalgesia, 293, 307 hyperkeratosis, 75, 264
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Index 465
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hypersensitivity, 96, 294 hypertension, 31, 231, 365 hypodermitis sclerodermaformis, 73 hypothyroidism, 54, 88
I
immunocompromised conditions,
254
immunosuppressant
agents, 113, 128
inelastic bandage, 358, 380, 392
in advanced practice, 393, 393
static stiness for, 380 infection, 253 infective conditions/infection, 110,
111, 172, 231 Buruli ulcers, 175–176, 176 ecthyma, 173 Hansen disease/leprosy, 175 leishmaniasis, 172, 173, 174
inltration of neutrophils, 110 inamed legs, 69–72 inamed skin, 125 inammatory/autoimmune
disorders, 107 pyoderma gangrenosum, 107–114 rheumatoid arthritis, 118–123 sickle cell disease, 130–134 systemic scleroderma, 123–130 vasculitis, 114–118
inammatory/inammation, 117
bowel disease, 108 conditions, 230 markers, 73 phase of wound healing, 36, 37 vascular disease, 32–33 of veins, 231
iniximab, 112, 118 interface pressure, 378–379 intermittent claudication, 30, 32 intermittent pneumatic
compression (IPC), 81, 397–398 contraindications to, 82
indications and contraindications
for, 398
types of ulceration, 397
International Association for the
Study of Pain (IASP), 285 intrinsic ageing, skin in, 432 intrinsic oxygenation, 253 ischaemia, 114, 129, 290, 306
chronic, 32 critical, 373, 384 limb‐threatening, 360, 373, 384 temporary, 30 tissue, 21, 29, 32, 131, 139 due to vessel damage, 114
ischaemic arteriolosclerosis, 139
K
Kaposi’s sarcoma, classic, 149 keratinocyte carcinomas, 146 kidney disease, 231 Kinesio tape, 80–81 Klebsiella pneumonia, 173 knitting needle syndrome, 334
L
Laplace’s law, 354, 371, 375, 381 laser therapy, 81–82 Leg Club Model, 443 Legs Matters, 234
campaign, 443 coalition, 344, 345
leg ulceration assessment, 226, 227
age, 227 alcoholism, 233 allergies or known sensitivities,
231–232
arterial disease, 248–252 atrophie blanche, 243 cancer diagnosis or
treatment, 230
cardiac vascular history, 230–231 diabetes/associated peripheral
neuropathy, 229
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466 Index
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leg ulceration assessment (Continued)
diagnostic assessment,
265–267, 268 diet and nutritional status, 232 DVT, 228 employment, 235 examination, 238 family/carer support, 234 family history, 227–228 haematological disorders, 230 haemorrhoids and constipation,
229 handheld Doppler performing
procedure, 268–276 hypertension, 231 infection, 231 inammatory and auto‐immune
conditions, 230 lipodermatosclerosis and venous
staining, 245 loneliness and isolation, 234 medical history, 228 medications, 228 mobility, 233–234 pain, 233 phlebitis, 231 pregnancy, 231 previous surgery, 228 previous trauma, 228 psychological status, 235 quality of life, 234 reassessment and recurrence, 276 red ags for urgent treatment of
patients with VLU, 276 respiratory disorders, 230 signs of ankle are, 246 signs of enlarged veins, 240 signs of hyperpigmentation,
staining and hyperkeratosis,
241
skin assessment, 263–264 sleep pattern and behaviour, 232 smoking, 233
stress, 233 varicose eczema, 242 wound assessment, 252–263
leg ulceration, atypical, 106
diagnosis of, 106–107 drug‐induced leg ulcers,
155–161
erosive pustular dermatosis,
161–172 infective conditions, 172–176 inammatory/autoimmune
disorders, 107–134 malignant/neoplastic
wounds, 145–155 metabolic disorders, 134–145 related to RA, 121
leg ulcer management, 318
common views of, 333 healthcare culture of, 335 inuences practitioners’ decision‐
making in, 329–330 problematic culture
within, 332–335 system delays impacts on patient
outcomes, 334
leg ulcer(s), 35
hosiery kits. See compression
hosiery kits management, 2, 7 pathways, 451 treatment, 2 types, 297
leishmaniasis, 172, 173, 174 leucocytes, 21 leukaemia, 108 lifelong management, 405
assessing for compression
hosiery, 413–415 awareness, 406–407 choosing and prescribing
hosiery, 415–423 choosing compression therapy
system, 423–434
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Index 467
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compression therapy systems,
411–413
empowering patients’ self‐
management for leg ulcer
prevention, 434–438 endovenous ablation, 411 factors inuencing venous ulcer
recurrence, 407–409 holistic reassessment, 409–411 knowledge, sta and train-
ing, 439–441 leg ulcer pathways, 450 patient satisfaction and quality
of life, 450 public health, 441–450 wound care, 405–406
lifestyle factors, 254 limb volume measurement, 64–65 Lindsay Leg Clubs, 234, 346 lipodermatoschlerosis, acute, 70 lipodermatosclerosis, 73, 245, 383 lipoedema, 55, 87. See also
lymphoedema ankles to demonstrate ’cu’
phenomenon, 91 classication, 94–95 diagnosis, 94 ‘hood’ of excess tissue, 93 impact of, 95 key dierences with
lymphoedema and obesity, 89 in practice, 88–94 treatment and management, 95–97 Type III late stage 2with chronic
oedema, 92 Type III, stage 2lipoedema, 90
lipoedema fat, 95 Lively Legs Model, 443 local wound:
care, 129, 165 management, 112–113, 118
loneliness and isolation, 234 long saphenous veins, 16
lower leg wounds, 3 lower limb:
assessment, 190, 226 leadership, 332 lymphoedema, 52 wounds, 1, 172, 405
lower limb ulceration
anti‐inammatory action of
compression therapy, 381–384 case for early intervention, 360 cautions and contraindications,
384–386 clinical management, 360–372 compression hosiery kit, 356 compression hosiery
stockings, 359 compression hosiery wrap, 357 compression of foot, 396–397 compression therapy and work
principle, 372–381 elastic bandage, 358 inelastic bandage, 358 intermittent pneumatic
compression, 397–398 location of ulceration, 396 multidisciplinary
approach, 353–354 recognition of leg ulceration, 355 tools in toolbox, 356–359 treatment of, 353, 386–395 wound bed preparation and
clinical management, 398
lower limb veno‐muscular
pumps, 192 calf muscle pump, 194 calf muscle pump dysfunction,
195–196 foot pump, 193–194 mechanism of action of
VMPs, 194–195 thigh pump, 194
lupus, 114 lymphatic capillaries, 44, 47
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468 Index
https://t.me/medicina_free
lymphaticovenular anastomosis
(LVA), 82
lymphatic system, 370
anatomy of, 44–45 function of, 43–48 in humans, 46 lymphatic ducts, 45 lymphatic uid, 43, 45, 51, 69, 83 lymphatic liposuction, 83 lymphatic trunks, 44
lymphatic vessels, 47 lymph nodes, 44, 46, 47, 83, 154 lymphocytes, 28, 45 lymphoedema, 3, 44–45, 48, 49, 50,
188. See also lipoedema
adjunct treatment
modalities, 79–82 assessment, 55 causes and exclusions, 60–61 causes of, 52–55 cellulitis and lymphorrhoea
history, 59 clinical examination, 61–64 compression therapy and
assessment considerations, 76–79 diagnosis, 57–59 factors inuence and contribute
to oedema, 54–55 history, 59 management challenges,
66–68, 67–68 measurements, 64–65 obstructive and non‐obstructive
causes of, 50 palliative care, 83–87 prevalence and key facts, 48–51 primary, 49 psychosocial impact, 65, 65–66 risk factors, 52, 53 screening and investigations, 61 secondary, 49 stages, 64 staging and severity, 64 surgery, 82–83
symptoms, 56 treatment, 74–76 types, 49, 50
lymphorrhoea, 7, 68
history, 59 primary, 49, 50, 55, 59
lymphovenous disease, 68
cellulitis, 73 lymphorrhoea, 69, 70 red or inamed legs, 69–72
M
maceration, 263, 264, 369
skin, 69
web‐space, 75 macrophages, 28, 37, 369 made‐to‐measure hosiery, 421 magnetic resonance angiogram
(MRA), 266
magnetic resonance imaging scans
(MRI scans), 154 malignancy, 110, 111, 145 malignant melanoma (MM), 146
amelanotic malignant
melanoma, 151
diagnosis, 153–154 examination, 150–153 history, 149–150 intervention, 154–155 investigations, 153 key risk factors and presentation
of, 147–148
weighted seven‐point
checklist, 151, 153 malignant/neoplastic
wounds, 145–155 malignant ulcer, 145 malnutrition, 74, 124, 128, 173 manual lymphatic drainage (MLD),
79, 80, 86 Marjolin’s ulcers, 146–155, 152 Martorell hypertensive ischaemic
leg ulcers (HYTILU). See
Martorell’s ulcers
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Index 469
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Martorell’s ulcers, 139, 140.
Seealsodrug‐induced leg
ulcers diagnosis, 140–141 examination, 139 history, 139 intervention, 141 investigations, 139–140
matrix metalloproteinase (MMP),
20, 369, 383
maturation phase of wound
healing, 36, 38–39
mechanical theory, 21 medication:
cause leg and foot ulceration,
362–364 cause or exacerbate swelling in
ankle and lower limb,
365–366, 366 management, 362
medications, 254 Medicines Healthcare Regulatory
Agency, 433
Mental Capacity Act (2005), 170 Mental Health Act (2007), 170 metabolic disorders, 134
calciphylaxis, 141–145 Martorell’s ulcers, 139–141 necrobiosis lipoidica, 134–139
metastatic tumours, 146 methicillin‐sensitive and–resistant
Staphylococcus aureus, 160
methotrexate, 156 metronidazole, 155 micronutrients, 124 microscopic polyarteritis, 115 mild compression therapy, 227,
360
mixed venous/arterial leg
ulceration, 297
mobility, 233–234
and exercise, 209 foot issues and, 209–216 walking and, 205–206
monocytes, 21, 37, 233 monolament testing for
neuropathy, 229
monophasic signal of
ABPI, 273, 274
motivational interviewing (MI),
342
multidisciplinary team
(MDT), 218, 355 muscular arteries, 28 musculoskeletal factors (MSK
factors), 188
allied health professionals as part
of MDT, 218
ankle joint assessment, 196–198 biomechanical factors, 189 lower limb veno‐muscular
pumps, 192–196
management, 205–216 reducing falls risk, 216–217 risk factors, 190–192
Mycobacterium leprae, 175 Mycobacterium ulcerans, 175
myocardial infarction (MI), 230,
231
N
National Institute for Health and
Care Excellence (NICE), 97,
151, 267, 353, 408 National Wound Care Strategy, 4,
329, 344, 442 National Wound Care Strategy
Programme (NWCSP), 106,
192, 360, 406, 442 necrobiosis lipoidica (NL), 134
diagnosis, 137 examination, 135–136 history, 135 intervention, 137–139 investigations, 136 reddened plaques to pretibial
region with, 136
ulcerated, 137
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470 Index
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necrobiosis lipoidica diabeticorum.
See necrobiosis lipoidica (NL)
necrosis, 117, 151 necrotic tissue or foreign bodies, 253 neoplastic or necrotic skin, 125 neoplastic ulcer, 145 neuropathy:
diabetes/associated
peripheral, 229 monolament testing for, 229 pain, 114, 293
neurosignature, 290, 292 neutrophils, 37, 110, 233 NHS Long Term Plan, 343, 441–442 nicorandil, 156, 362–363 nocebo eect, 309, 310 nociceptive pain, 114, 293 nociceptive pain signals, 288 nociceptors, 288, 293 non‐cosmetic liposuction (NCL), 97 non‐lipoedema fat, 95 non‐melanoma skin cancers, 146 non‐painful sensations, 289 non‐steroidal anti‐inammatory
drugs (NSAIDs), 117
non‐venous ulceration, 365 normal venous function, 11–16
blood ow from capillaries to
venules, 13 one‐way bicuspid valves, 14 transportation of blood
around body, 12
nurse‐led bandage regime, 167 Nursing and Midwifery Council
(NMC), 331
nutrition, 254
O
obesity, 31, 89, 203–204, 254 obstructive causes of
lymphoedema, 50
odorous exudate, 370 oedema, 51, 64, 253, 395
o‐the‐shelf hosiery, 422 one‐time ulcer, 131 online dressing optimisation
system, 8
online non prescription
services, 7–9 opioids, 307, 309 organisational change, 339 organisational culture, 7, 332 orthosis, 215
P
pain, 233, 254, 285
alternative tools for
exploring, 302
analgesia, 306–308 assessment scales, 300 biopsychosocial model,
290–292
causes, 292, 296 compression therapy, 308–309 cycles, 295–296 descriptors, 294 experience, 285–287, 301 gate theory, 288–289 impact on people’s lives, 296–297 key management messages,
304–306, 312
management, 114, 129, 298–303,
306–308
psychosocial management,
309–311
questions to understanding
patients’ pain, 298
theory evolution, 287–288 types, 293–295 uncontrolled, 268
palliative care, 83, 385
assessment, 85 compression therapy, 86 end‐of‐life diseases with
lymphoedema, 84
management, 86
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Palliative Care Outcome Scale
(PCOS), 85 palpable purpura, 117 Pascal’s law, 354, 375, 381, 396 Pascal’s principle. See Pascal’s law pathergy, 108, 110, 111 patient activation:
personal health management
through, 339–340
rationale for, 339
patient activation measure (PAM),
339, 340–341, 341 patient‐centred intelligence, 339 patient education, 76
lymphoedema, 77 in understanding
hosiery, 429–431 patient satisfaction and quality
of life, 450 patient self‐care, 166–168 peau d’orange, 61, 63, 88 peer support groups, 345–346 pentoxifylline, 138, 364–365 people who inject drugs
(PWIDs), 157
diagnosis, 160 drug‐taking history in, 159 examination, 159–160 history, 157–159 intervention, 160–161 investigations, 160
leg ulceration in, 157–161 perforator veins, 15, 16 peripheral arterial disease (PAD),
32, 119, 227, 253, 384–385
recurrence in patients with,
408
6Ps of, 248, 252 peripheral arterial occlusive disease
(POAD), 26, 29–30 peripheral oedema, 268 peroneal tibial artery, 270 personalised care, 134
challenging non‐compliance,
335–337
evidence‐based clinical
management, 318
inuence of condence, courage
and competence, 330–332
inuences practitioners’ decision‐
making, 329–330
key areas of public health
practice, 326 Legs Matter coalition, 345 making eective change, 326–329 negative terminology, 346 patient activation measure,
340–341 peer support groups, 345–346 personal health management,
339–340 positive descriptors, 347 positive language to promoting
positive culture, 346–347 problematic culture within leg
ulcer management, 332–335 public help interventions, 325 social, environmental and
cultural context of health, 319 social prescribing, 342–343 supporting self‐management,
343–345 understanding lived experience,
338–339 wider determinants of
engagement, 324 wider or social determinants of
health, 319–324, 320
PG, acne and suppurative
hidradenitis (PASH), 108
phagocytosis, 37 phlebitis, 228, 231 phototherapy, 138 physical activity, 204–205, 434 Plan–Do–Study–Act cycle (PDSA
cycle), 444–446, 445
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