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Ординатура / Офтальмология / Учебные материалы / Vitreoretinal Surgery Farenc Kuhn Springer.pdf
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Retinal Detachment

54

 

RD1 is deÞned as a condition in which the neuroretina is separated from the RPE. Based on the etiology and characteristics, several types are distinguished; these are summarized in Table 54.1.

54.1The Pathophysiology of RD2

Separation of the neuroretina from the RPE is used to be a blinding condition.3 It is thus not surprising that so many misconceptions related to this condition have been born. Many of these live on, even though our knowledge of the pathophysiology of RD has greatly expanded since (see Table 54.2).

In the vast majority of cases, regardless of the etiology, the cascade of events leading to RD development is identical4 (see Sect. 26.1.2 and Fig. 54.1). While dynamic VR traction is the cause of break formation, the type of the break has important implications regarding the events to come, including management (see Table 54.3), as does the condition of the vitreous and the VR interface (see

Figs. 26.1 and 54.2).

1This chapter is much longer than the others in this part, due to the clinical signiÞcance of RD, the numerous controversies related to it, and the no fewer then 3 available treatment options, which need to be discussed in detail (even then, space limitations forced me to be rather brief; compare the length of this chapter to a great book on RD [see further reading], which has 1,138 pages). The reader is also reminded that this chapter is about rhegmatogenous detachment only.

2Retinal detachments that are nonrhegmatogenous are discussed in Chaps. 51, 52, 53, 55, and 56.

3In 1912, a large study reported a surgical success rate of 0.1%.

4One notable exception is trauma causing a direct retinal lesion: here the formation of the break precedes the changes in the vitreous. However, even in these eyes the vitreous changes will occur prior to the development of the RD.

© Springer International Publishing Switzerland 2016

449

F. Kuhn, Vitreoretinal Surgery: Strategies and Tactics,

DOI 10.1007/978-3-319-19479-0_54

450

54 Retinal Detachment

 

Table 54.1 Detachment of the retina: types and characteristics*

Detachment

Comment

Rhegmatogenous

A retinal break (ÒrhegmaÓ) is present, but the primary culprit is VR

(ÒRDÓ)

traction, which is dynamica

 

The conÞguration is convex

Tractional (ÒTRDÓ)b

There is very strong VR or subretinal traction, but no break. The

 

traction is staticc

 

The conÞguration is concave

Combined

The tractional component dominates, even though a break is also present.

rhegmatogenous

The tractional element precedes the development of the break

and tractional

The conÞguration is concave

Central (posterior,

Although VR traction is presente, the main culprit is the staphyloma;

staphyloma

the rigid ILM does not allow the otherwise elastic retina to conform

spanning)d

to the scleral bulge

 

A macular hole may be present, but it is likely to be the consequence,

 

not the cause of the RD

 

The conÞguration is convex or concave, depending on the size of the

 

staphyloma and the height of the RD

Exudative/serous

There is no traction, simply secretion of ßuid into the subretinal space.

 

The ßuid is either too voluminous or too viscous for the RPE to

 

remove. Examples include optic pit (surgical intervention is worth

 

considering, see Chap. 51) and central serous chorioretinopathy

 

(not a surgical indication)

 

The conÞguration is convex

Hemorrhagic

There is no traction; the bleeding is typically traumatic in origin or

 

associated with AMD

 

The conÞguration is initially convex but can become uneven as the

 

blood start to absorb

*This condition (see below, Sect. 54.5.2.4) virtually never occurs if PPV is employed.

aThat is, its direction and strength are dependent on, and change with, movements of the eyeball and head. The conÞguration of the detachment changes if the head position changes.

bSee Chap. 55.

cThat is, its direction and strength are independent of, and do not change (or only insigniÞcantly) with movements of the eyeball and head, nor will a head-position change impact the conÞguration of the detachment.

dSee Chap. 56. eThere is no PVD.

54.1.1 RD Due to a Horseshoe or Giant Tear

The initial step is a change in the structure of the vitreous gel (see Sect. 26.1.2). With the vitreous cavity containing both gel and ßuid-Þlled pockets, it becomes possible for the gel to become mobile. With every movement of the eyeball or head, traction forces act on the retina at all sites of vitreoretinal adhesion (see Sect. 26.1.1).5

5 A patient recently asked me whether he can go skiing since he recently underwent laser treatment for 2 retinal tears that developed after he saw ßashes. He has numerous ßoaters in the eye and still sees ßashes. I told him he has a higher risk developing RD due to reading than skiing. Movements of the eye are extensive when reading (or watching in person [not on TV] a tennis match) but rare while on skis.

54.1 The Pathophysiology of RD

451

 

Table 54.2 RD pathophysiology and treatment: traditional and revised concepts*

Variable

Traditional concept

Revised concept

PVD in old age in an eye

Very likely to be present

May or may not be present

with attached retina

 

 

PVD progressing in an

The highest risk for RD

True Ð except that the PVD may be

eye with attached

development

anomalous

retina

 

 

If VR traction is not seen

There is no VR traction

VR traction still may be present, but

at the slit lamp or on

 

it is undetectable with current

OCT

 

methodology and technology

PVD as a preoperative

Straightforward to make as

Impossible to make with any kind of

diagnosis

at least one of the

certainty:

 

following is present:

1. The distant surface seen on

 

1. On biomicroscopy (or

biomicroscopy (or on OCT)

 

on OCT) a surface,

may indeed be PVD but may

 

distant from the

also be the anterior wall of a

 

posterior retina

vitreoschisis cavitya

 

2. Weiss ring

2. The Weiss ring indicates that

 

 

the vitreous is detached at the

 

 

disc, but not necessarily that it

 

 

also detached elsewhere in the

 

 

posterior pole

PVD in an eye with RD

Always present

May be complete, partial, or

 

 

completely absent

Primary causative

The retinal break (the RD is

VR traction (the RD is

pathology in RD

ÒretinogenicÓ)

ÒvitreogenicÓ); the retinal break is

 

 

secondary to the traction

The initial element in the

PVD

Syneresis

cascade leading to

 

 

break/RD development

 

 

Whether a retinal break

Depends on the size of the

Depends on the strength of the VR

leads to RD

break (and possibly the

traction as well as on the RPE

 

strength of the VR

pump, the strength of the IPM,

 

traction)

and the resistance (tensile

 

 

strength) of the retina itself

 

 

The volume of the incoming ßuid

 

 

must exceed the capacity of the

 

 

RPE to remove it

Presence of an

Signals strong traction and

Signals strong past traction and thus

operculumb

thus signiÞcant RD risk

reduced RD risk

PVD in a highly myopic

Present

What is seen as a PVD is in reality a

eye with posterior RDc

 

vitreoschisis

PVD in PDRd

Present, anteriorly (Òtable-

A vitreoschisis is present, not a PVD

 

top RDÓ)

 

The VR interface in an

There is a complete PVD

The ÒPVD posterior to the break, but

eye with RD

posterior to the break but

no PVD anterior to the breakÓ

 

complete vitreous

statement may hold true for the

 

adherence to the retina

eye just examined

 

anterior to the break

However, the PVD may also be

 

 

incomplete (anomalous) or

 

 

nonexistent

 

 

(continued)

452

 

54 Retinal Detachment

 

 

 

Table 54.2 (continued)

 

 

Variable

Traditional concept

Revised concept

PVD-associatede retinal

Located at the posterior edge

Located between the vitreous base

tear

of the vitreous base

and the equator, occasionally

 

 

even more posteriorly

Primary target of

The retinal break

The VR traction

treatment

 

 

Gas use for RD in PPV

The effect is a tamponade,

The effect is partially a tamponade

 

with two goals in mind:

but also a reduction in ßuidic

 

Prevent ßuid from getting

shearing

 

under the retina

By occupying space in the vitreous

 

Press the retina against the

cavity, limit the shearing the ßuid

 

RPE until the ÒpexyÓ

would cause on the retinal surface,

 

takes effect

thereby reducing the risk of retinal

 

 

separation from the RPE

 

 

Press the retina against the RPE until

 

 

the ÒpexyÓ takes effect

Vitreous removal in an

It is crucial to do a complete

Several steps are crucial

eye with RD

(total) vitrectomy in the

Creation of a PVD if it has not

 

periphery

occurred before

 

 

Total vitrectomy in the periphery

 

 

Removal of the anterior vitreous face

*See the text for more details. RDs that are nonrhegmatogenous are also included.

aThe anterior (inner) wall of the vitreoschisis cavity is mobile (hence the similarity in appearance to a PVD), but its posterior (outer) wall is static (see Fig. 26.2).

bDeÞned as a piece of the retina (i.e., the formal tear) that is now ßoating in the vitreous, with no direct connection to the rest of the retina.

cIt is not a true rhegmatogenous retinal detachment, even if a macular hole is present. dObviously, this is not an eye with rhegmatogenous retinal detachment (see Chap. 52). ePVD, which may be true PVD or anomalous.

 

Gel normal

 

 

 

Syneresis

VR adhesion

 

RPE pump, IPM glue

VR traction

 

 

Retinal tear-

 

Retinal tear +

RPE pump, IPM glue

RD -

 

 

Flapped

 

 

Operculated

 

RD +

54.1 The Pathophysiology of RD

453

 

Table 54.3 ClassiÞcation of retinal breaks and its implications for treatment

Breaka

Comment

Management implication

Hole, round

A necrotic type: the retina

SB is an efÞcient method of treatment

 

dissolves. Clinically detectable

 

 

traction may also be present Ð

 

 

this is the case when the hole is

 

 

in an area of lattice degeneration

 

Hole, macular

It is not perceived as a true RD

A unique operation is needed

 

since only of a small ring of

(see Sect. 50.2.4)

 

subretinal ßuid is present around

 

 

the hole (Òßuid cuffÓ)b

 

Hole, macular, in

There is a high risk of central RD;

A unique operation is needed

a highly

in fact, the RD often Ð if not

(see Sect. 56.2)

myopic eye

always Ð precedes the formation

 

 

of the hole

 

Dialysis

Usually caused by contusion, the

SB and PPV are equally efÞcient

 

retina separates at the ora serrata;

methods of treatment; both have

 

since the vitreous is healthy at the

their own advantages, risks, and

 

time of the injury, the progression

side effects

 

to RD is usually slowc

 

Tear, horseshoe/

Caused by VR traction, the opening

Depending on the location, strength of

ßap

in the retina faces the posterior

traction, pigment content in the

 

pole (the base of the ßap is

vitreous and many other variables,

 

anterior). This is the most

SB and PPV may or may not be

 

common cause of RD

equally efÞcient methods of

 

 

treatment. If PPV is performed, the

 

 

ßap must be removed to completely

 

 

alleviate the traction that caused it

 

 

(see the text for more details)

Giant tear

A tear that runs parallel to the

PPV is the treatment of choice;

 

limbus and exceeds 3 clock

adding a buckle may increase the

 

hours in length; the central edge

risk of slippaged. The curled central

 

is often inverted

edge must be completely cut and

 

 

silicone oil implanted due to the

 

 

high risk of PVR

aA break is deÞned as an interruption in the contiguity of the neuroretina. bSee Chap. 50.

cIn other words, a healthy vitreous tamponades the break; once vitreous movement becomes possible as a result of syneresis, the RD risk dramatically increases.

dThe central retinal edge moves posteriorly, preventing retinal reattachment.

Fig. 54.1 The cascade of events leading to RD.6 (as a reminder, rhegmatogenous, not tractional, RD is discussed here). In areas of VR adhesion, a syneretic vitreous will cause VR traction, but it does not inevitably lead to the formation of a retinal break because the RPE pump and the IPM (plus the retinaÕs own tensile strength and the IOP, not shown here) are able to overcome the effect of the dynamic traction. Even if a break does develop, the RPE pump and the IPM may be able to counter the effect of the dynamic traction. If the torn retina becomes operculated, the risk of RD is dramatically reduced but not completely eliminated since there still may be VR traction on the retina surrounding the break. RD results only when the traction force overpowers the effect of the RPE pump and the IPM

6 As a reminder, rhegmatogenous, not tractional, RD is discussed here.

454

54 Retinal Detachment

 

 

a

V

R

C

b

B

c

d

e

54.1 The Pathophysiology of RD

455

 

 

Traction that caused a retinal tear is also able to keep the break open so that ßuid from the vitreous has direct access to the (so far virtual) subretinal space.9 Once the volume of ßuid entering exceeds the capacity of the RPE to remove it, an RD ensues.

Pearl

The operculation of the retinal tear means that traction in the area of the break itself has ceased to exist. The torn-out piece of the retina is suspended in the gel or is ÒswimmingÓ in a pool of ßuid in the syneretic pocket (see Fig. 54.3). The retina remains attached if there is no remaining traction in the vicinity but may detach if there is sufÞciently strong traction on the retinal edge. The operculum is thus a relative, not an absolute, contraindication against prophylactic laser (see below, Sect. 54.2.4).

Fig. 54.3 The operculum in the vitreous cavity. The operculum is visible as a little gray spot; the shadow it casts on the retina is seen just above the port of the probe. The area of degeneration where the small piece of retina was torn from is obvious from the pigmentation there

Fig. 54.2 Relationship between the vitreoretinal interface, a retinal break, and RD. (a) If the vitreous is a healthy gel and there is no retinal break, RD does not occur. (b) Even if a retinal break (arrow) does occur, as long as the vitreous is a healthy gel, RD does not occur.7 (c) Even if a retinal break does occur, should a total PVD also be present, RD does not occur. (d) In the presence of a retinal break and a syneretic gel, there is a risk of traction at the edge of the break. (e) If the VR traction overcomes the sum of forces holding the retina in place (mainly the RPE pump and the IPM), an RD develops.8 V vitreous, R retina, C choroid, B retinal break

7The vitreous acts as a plug over the break.

8The vitreous acts as a corkscrew.

9Think about a door held open to allow access to the room.

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