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Ferenc Kuhn

Vitreoretinal Surgery

Strategies

and Tactics

123

Vitreoretinal Surgery: Strategies and Tactics

Selected wisdoms for the aspiring VR surgeon

Vitreoretinal surgery: the easy thing that is hard to do (paraphrasing Bertold Brecht). Even a journey of a thousand miles begins with a single step (Chinese proverb).

Anyone who has never made a mistake has never tried anything new (Albert Einstein).

The reception of outlandish ideas: First, “it’s completely impossible.” Second, “It’s possible but not worth doing.” Third, “I said all along that it was a good idea”. (Sir Arthur C. Clarke).

If I had had listened to my customers, I would have improved the horse and buggy (Henry Ford).

You can resist an invading army, but no power on earth can stop an idea whose time has come (Victor Hugo).

The important thing is not to stop questioning. Curiosity has its own reason for existing (Albert Einstein).

The difference between good and almost good is like the difference between the lightning bug and lightning (Mark Twain).

Everything should be made as simple as possible, but not simpler (Albert Einstein). Simplicity is the ultimate sophistication. It takes a lot of hard work to make something

simple (Steve Jobs).

What you see is what you get. What you don’t see gets you.

Hobson’s choice is a free choice in which only one option is offered. Decisions are easy when no options are left (Narasimha Rao). Doubt is not a pleasant position but certainty is absurd (Voltaire).

The surest sign of insanity is being certain without having any doubt (Andrew Feldmar). Self-delusion is the first step towards disaster (Raghuram Rajan).

Having a bad strategy is better than not having a strategy at all (Sir Winston Churchill). No battle plan survives the first contact with the enemy (Helmuth von Moltke).

We either find a road or we build one (Hannibal).

They said it couldn’t be done, but that doesn’t always work.

Insanity is doing the same thing over and over again and expecting different outcomes (Albert Einstein).

Do not fear to be eccentric in opinion, for every opinion now accepted was once eccentric (Bertrand Russell).

What was yesterday’s gold standard is today’s dogma; what was yesterday’s craziness is today’s gold.

You are neither right nor wrong because the crowd disagrees with you. You are right because your data and reasoning are right (Benjamin Graham).

You cannot learn to play the piano by going to concerts.

Don’t pay attention to the critics. Don’t even ignore them (Sam Goldwyn).

Care more particularly for the individual patient than the special features of the disease (Sir William Osler).

Ferenc Kuhn

Vitreoretinal Surgery:

Strategies and Tactics

Ferenc Kuhn, MD, PhD

St. Johns, FL

USA

Helen Keller Foundation

for Research and Education

International Society of Ocular Trauma

Birmingham, AL

USA

Consultant and Vitreoretinal Surgeon

Milos Eye Hospital

Belgrade

Serbia

Consultant and Vitreoretinal Surgeon

Zagórskiego Eye Hospital

Cracow

Poland

ISBN 978-3-319-19478-3

ISBN 978-3-319-19479-0 (eBook)

DOI 10.1007/978-3-319-19479-0

 

Library of Congress Control Number: 2015947620

Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.

The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made.

Printed on acid-free paper

Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Preface: Read me First1

Even in the digital age, books printed on paper remain popular with readers.2 They are a great collection of knowledge presented in a concise, edited format. Scientific books in particular offer a single source of expert opinion, typically richly illustrated, and they continue to provide the reader the magic of holding a physical copy in his hand. A book can be carried around and be accessible even in areas with no internet service.3

Today’s scientific books are typically written by multiple authors, typically with very limited editing.4 With occasional exceptions, each chapter in each book ends with a long list of references,5 seemingly providing support for every major claim the chapter makes. While such books have obvious merit, Vitreoretinal Surgery: Strategies and Tactics is different.

This book was written by a single author, reflecting his over-30-year experience in the field. Crucially, this author claims neither that his approach to vitreoretinal (VR) surgery is the only nor the best option; many surgeons will find parts of this book objectionable or have a different (better) solution to a particular problem than the one described here.6

Why this author has chosen to present that particular option for a particular pathology at this particular point in time,7 however, does have a reason. It is the

1See the Appendix, Part 2.

2They do not necessarily compete with electronic versions either, as this book proves.

3This is true even though an online (electronic) version has its own advantages, such as being fully searchable. A hybrid between a printed and an online book is one available on an electronic reader (iPad, Kindle), which is easy to carry around.

4It is rather common to have the same topic addressed by more than one author in an edited book, and the information is all too often contradictory.

5Sometimes a chapter has more pages dedicated to the references than to the main topic itself.

6Let me illustrate this point with one example: reoperation in eyes with silicone oil tamponade and the need to keep the oil after surgery. I used to do the membrane removal under oil, but abandoned this because, among others, I want to see the true (“oil-free”) anatomy of the retina in order to address all abnormalities and because with the silicone oil freshly implanted, the “emulsification clock” is reset. Other surgeons, perhaps just as reasonably, will argue in favor of working under the original oil.

7The solution to a specific problem evolves over time; what has been true for a number of years may not be true tomorrow as new options, techniques, and technologies emerge.

v

vi

Preface: Read me First

 

 

author’s responsibility to describe not only what he does, how he does it, and when he does it; above all, he must explain why he does it. The reader will then have an opportunity to contemplate that “why” and make a conscious decision as to whether he agrees and so will employ it himself or, again based on a conscious thought process, decide against it – just as well, as long as the decision against is not a random one.

This book has no references, only a few important publications are listed as “Further Reading.” References in the internet age are nowhere near as important in a book as they once were. Besides, the statements made, the issues emphasized, the surgical solutions offered in this publication represent a synthesis of the author’s experience. What is described here may have as its birthmother his own brain, that of a colleague during an informal conversation, a publication, or a presentation at some meeting; either way, the original idea has surely evolved over time.

This is a very practical-oriented book, presenting the reader with both strategic and tactical questions about VR surgery (and the surgeon himself). Everything in this publication serves as an agent provocateur to incite the reader to develop his own, individualized approach to each patient, to each surgery. It is not the goal of the book to create copies of the author-surgeon; it is a goal of the book to encourage the reader to make conscious decisions before, during, and after surgery,8 to develop his own, unique method for working as a VR surgeon. The author recommends spending a few minutes by listening to a wonderful song9 that so beautifully, so elegantly describes this singular approach (the lyrics are also published at the end of the Preface).10

The format of this book is rather unusual. The reader will find few lengthy paragraphs; these are mostly replaced by bullet points, tables, and text boxes such as Pearls and Q&A. This format hopefully makes it easier to read the book and find the necessary information fast. Furthermore, the book is partially written in the first person11 and refers to the surgeon and the patients as “he”12 – for no reason other than simplicity.

I tried to mimic as much as possible the most ideal teaching situation: an experienced surgeon actively assisting the fellow. This requires providing specific advice as the fellow progresses with the case and questions/issues arise. My own approach to VR surgery is a very conscious one. This helps me foresee many of the problems

8A good example is a recent lecture the author heard: the speaker described a diabetic patient receiving 36 monthly injections into a single eye with macular edema. Obviously, the treatment became an automated process, and the ophthalmologist forgot to stop at some point during the 3 years to look at the big picture, and ask: Isn’t there something wrong here if the patient must come back for the very same thing every single month for 3 years and the pathology recurs every time?

9https://www.youtube.com/watch?v = 6E2hYDIFDIU

10An honest speaker asks his audience of trainees not to believe a word he (or anybody else) tells them. They should carefully listen to what they are told, test the teaching in their own practice, and then decide whether they accept, reject, or modify it.

11Rather than, as is typical, the author referring to himself in the third person.

12Except the OR nurse, who is a “she.” I have worked, throughout my career, very closely with 17 nurses, each a female.

Preface: Read me First

vii

 

 

that emerge as surgery is performed by the fellow (or myself). I tried to construct this book as if addressing these questions while assisting a younger colleague. Naturally, not all situations can be anticipated and thus described in the book, but I believe the most common ones will have been.

I attempted to structure the contents so that they follow a rational order and avoid repetition as much as possible. However, I am aware that this is an impossible task.13 I also made an effort not to present information a well-trained, past-residency- training ophthalmologist (aspiring to be a VR surgeon) is supposed to already know.

The opening part is a rather unique one since it discusses issues that are virtually never raised: who should and who should not be a VR surgeon, and how to train to become one in a country without a formal fellowship. This part is followed by two parts about the basic rules the surgeon must keep in mind before the actual surgery; the fourth part deals with the fundamentals of VR surgery, while the fifth is dedicated to tactical issues per indication.

I do not recommend that the reader go straight to a chapter in the last two parts of the book without reading (all) the prior parts first; the chapters in Parts 4 and 5 were written with the assumption that the reader had gone through all preceding chapters.

The book is based on the “standard 3-port” approach to vitrectomy, using the microscope and the BIOM (macular contact lens) for viewing. One chapter (17) briefly describes the alternative approaches. All issues discussed relate to 23 g transconjunctival vitrectomy, unless otherwise indicated.

The book is not written for fellows residing in any specific country. While VR surgeons in countries with an advanced health-care system may find certain aspects of what is discussed here superfluous,14 young surgeons in many, less advanced countries are likely to have to deal with such issues. Furthermore, even in advanced countries it is still helpful for the fellow to consciously address every possible component of VR surgery, from the correct posture during surgery to using the forceps in the most ideal way.15

The primary target audience of this book is the ophthalmologist who is either contemplating whether to become a VR surgeon or who is already in training, whether as part of a formal fellowship or, more commonly, an informal one. I sincerely hope, however, that the book will also be useful to my very experienced colleagues: the training of the VR surgeon is never complete. Throughout these 3 decades I have visited numerous ORs and without exception found some “trick” that was interesting so that I have decided to try it myself – or something that made me murmur to myself: “thank God I never tried this.” Either way, the visit proved

13Eventually, a choice has to be made between “vertical” and “horizontal” structuring. For example, one cannot group everything that concerns the lens in a single location; the lens has to be mentioned in the chapter on visibility as well as in several chapters dealing with strategy and tactics.

14Describing the characteristics of “the” ideal chair for vitrectomy, setting up the vitrectomy machine etc.

15At what angle should I peel the ILM in an eye with severe macular edema?

viii

Preface: Read me First

 

 

useful: whatever it is that forces a surgeon to make conscious, rather than automated, decisions during surgery is a positive thing. The most important is for the surgeon never to be on autopilot; he must avoid making decisions and surgical maneuvers based on reflex or custom.

In summary

Scientific books are impersonal – this book is not. They typically have multiple authors – this book has only one. They contain page after page of references – this book presents none, only a list of “Further Reading”. They usually address larger issues, not technical details – this book attempts to do both.

My Way lyrics:

And now, the end is near;

And so I face the final curtain.

My friend, I’ll say it clear,

I’ll state my case, of which I’m certain.

I’ve lived a life that’s full.

I’ve traveled each and ev’ry highway;

And more, much more than this,

I did it my way.

Regrets, I’ve had a few;

But then again, too few to mention.

I did what I had to do

And saw it through without exemption.

I planned each charted course;

Each careful step along the byway,

And more, much more than this,

I did it my way.

Yes, there were times, I’m sure you knew

When I bit off more than I could chew.

But through it all, when there was doubt,

I ate it up and spit it out.

I faced it all and I stood tall;

And did it my way.

I’ve loved, I’ve laughed and cried.

I’ve had my fill; my share of losing.

And now, as tears subside,

I find it all so amusing.

To think I did all that;

And may I say – not in a shy way, “Oh no, oh no not me,

I did it my way.”

Preface: Read me First

ix

 

 

For what is a man, what has he got?

If not himself, then he has naught.

To say the things he truly feels;

And not the words of one who kneels.

The record shows I took the blows –

And did it my way!

Yes, it was my way.

(by Jacques Revaux and Gilles Thibault)

Ferenc Kuhn, MD, PhD

Birmingham, AL, USA

Belgrade, Serbia

Cracow, Poland

Acknowledgment

Without continual support, a VR surgeon cannot become one or function as such. The complete list of individuals who stood behind and with me in this endeavor is too long to include here: I am able to provide the names of only a selected few.

I am very grateful to my wife, Maria, and my two daughters, Sophia and Judit, who graciously accepted that I was away so much and that my professional life shortchanged them in many ways, and still gave me nonstop encouragement. Without my parents’ support I would never have made it to medical school and certainly not into ophthalmology.

I would like to thank those individuals who gave their best to train me as a VR surgeon: Klaus Heimann, Relja Zivojnovic, and Veit-Peter Gabel. I am greatly indebted to colleagues with whom I have worked for many long years, discussing strategy and tactics on a daily basis: Viktoria Mester, Robert Morris, and Zora Ignjatovic.

I very much appreciate the two talented, aspiring colleagues who read the drafts of this book and gave me valuable feedback, Agnieszka Kardaszewska and Gabor Somfai, and the many excellent nurses who have assisted and advised me in various operating rooms in several countries for over three decades. I am also grateful for the comments on the manuscript of my peer and good friend, Wolfgang Schrader.

Last but not least, I need to thank my patients whose feedback has served as a recharge for my often depleted emotional battery.

xi

Abbreviations and Glossary

AC

Anterior chamber

Air-test

F-A-X to examine whether the detached retina is short-

 

ened or wrinkled

AMD

Age-related macular degeneration

Anomalous PVD

Areas of VR adhesion remain although some or most of

 

the cortical vitreous has separated from the retina

 

posteriorly

Anterior vitrectomy

Removal of the vitreous from the frontal part of the vit-

 

reous cavity (not vitrectomy in the AC or vitrectomy

 

performed via an anterior approach)

BIOM

Binocular indirect ophthalmo-microscope

BRVO

Branch retinal vein occlusion

BSS

Balanced salt solution

C3F8

Perfluoropropane gas

Cannula

Unless otherwise indicated, this is the 23, 25, and 27 g

 

(rarely 20 g) transscleral, metal tube that is inserted

 

through the conjunctiva and sclera to provide access

 

to the vitreous cavity during vitrectomy. In routine

 

surgery, one of these is for the housing of the infusion

 

cannula; the others are for the light pipe and instru-

 

ments such as the probe. The infusion cannula is

 

referred to as such; it is a “cannula within the can-

 

nula” when in place

Cellophane maculopathy

The earliest stage of EMP development: no membrane is

 

visible on the retinal surface, but the ILM is

 

wrinkled

CEVE

Complete and early vitrectomy for endophthalmitis

CNV

Choroidal neovascular membrane

Combined RD

Combined tractional and rhegmatogenous RD

Complete PPV

Total PPV

cpm

Cut per minute

CRVO

Central retinal vein occlusion

cst

Centistokes

xiii

xiv

Abbreviations and Glossary

 

 

Dropped nucleus

Even if the lens material found in the vitreous cavity is

 

cortex, not nucleus, this is the term used for lens par-

 

ticles that got lost posteriorly during phaco

EAV

Endoscopy-assisted vitrectomy

ECCE

Extracapsular cataract extraction

ECH

Expulsive choroidal hemorrhage

EMP

Epimacular proliferation (a.k.a. macular pucker, epi-

 

macular membrane, epiretinal membrane, macular

 

epiretinal proliferation etc.)

FA

Fluorescein angiography/angiogram

F-A-X

Fluid-air exchange

IBO

Indirect binocular ophthalmoscopy

ICCE

Intracapsular cataract extraction

ICG

Indocyanine green

ILM

Internal limiting membrane

IOFB

Intraocular foreign body

IOL

Intraocular lens

IOP

Intraocular pressure

IPM

Interphotoreceptor matrix

IR

Infrared

IRMA

Intraretinal microvascular abnormality

IU

International unit

LCD

Liquid crystal display

Lens

Crystalline lens

Lens (IOL) luxation

The lens (IOL) is completely dislocated. It may be in the

 

AC, vitreous cavity, subretinal space, suprachoroidal

 

space

Lens (IOL) subluxation

The lens (IOL) is decentered but does not completely

 

leave its normal position

LP

Light perception

ME

Macular edema

MIVS

Transconjunctival vitrectomy (the term stands for

 

micro[minimal]-incisional vitrectomy surgery)

MVR

Micro-vitreo-retinal (blade etc.)

N/A

Not applicable

Nurse

OR nurse, the VR surgeon’s assistant

Oil

Silicone oil; “normal” if its viscosity is 1,000–1,300 cst

 

and the density is <1

OR

Operating room

P-A

Posterio-anterior

PDR

Proliferative diabetic (vitreo)retinopathy

PFCL

Perfluorocarbon liquid (any type of heavier-than-water

 

intraocular fluid used as a temporary tamponade)

Phaco

Phacoemulsification

Phacologist

A cataract surgeon for whom the eyeball is a superfluous

 

attachment to a capsular bag. The latter demands the

 

implantation of the IOL into it, at any cost

Abbreviations and Glossary

xv

 

 

PK

Penetrating keratoplasty

Posterior cortical vitreous

Posterior vitreous face, posterior hyaloid face,

 

posterior vitreous cortex

PPL

Pars plana lensectomy

PPV

(Pars plana) vitrectomy

Probe

Vitrectomy probe/vitrector/cutter

PVD

Posterior vitreous detachment. PVD means sepa-

 

ration of the vitreous cortex from the retina in

 

the posterior pole, usually understood as up to

 

the equator

PVR

Proliferative vitreoretinopathy

Q&A

Question and answer

RD

Retinal detachment (rhegmatogenous unless men-

 

tioned otherwise)

ROP

Retinopathy of prematurity

RPE

Retinal pigment epithelium/epithelial

RVO

Retinal vein occlusion

SB

Scleral buckle/buckling

Scleral indentation

Scleral depression

Scraper

Tano diamond-dusted membrane scraper

SDI

Stereoscopic diagonal inverter (BIOM)

SF6

Sulfur hexafluoride gas

Steroid

Corticosteroid

TA

Triamcinolone acetonide (Kenalog)

TKP

Temporary keratoprosthesis

tPA

Tissue plasminogen activator

TRD

Tractional RD (diabetes, PVR, etc.)

Trocar

The tool (“MVR” blade) used for creating the

 

conjunctivo-scleral incision for cannula-

 

placement in transconjunctival surgery

UV

Ultraviolet

VA

Visual acuity

VEGF

Vascular endothelial growth factor

VH

Vitreous hemorrhage

Visco

Viscoelastic material

Vitreous base/retinal periphery

The area around the ora serrata where the 10-layer

 

neuroretina and vitreous gel normally terminate

Vitreous cushion

A layer of vitreous lining the retina (typically

 

exceeding the thickness of the cortex)

VMTS

Vitreomacular traction syndrome

VR

Vitreoretinal

vs

Versus

YAG (laser)

Neodymium-doped yttrium aluminum garnet laser

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