- •Contents
- •General Introduction
- •Objectives
- •Introduction
- •1 The Science of Refractive Surgery
- •Corneal Optics
- •Refractive Error: Optical Principles and Wavefront Analysis
- •Measurement of Wavefront Aberrations and Graphical Representations
- •Lower-Order Aberrations
- •Higher-Order Aberrations
- •Corneal Biomechanics
- •Corneal Imaging for Keratorefractive Surgery
- •Corneal Topography
- •Corneal Tomography
- •Indications for Corneal Imaging in Refractive Surgery
- •The Role of Corneal Topography in Refractive Surgery
- •Corneal Effects of Keratorefractive Surgery
- •Incisional Techniques
- •Tissue Addition or Subtraction Techniques
- •Alloplastic Material Addition Techniques
- •Collagen Shrinkage Techniques
- •Laser Biophysics
- •Laser–Tissue Interactions
- •Fundamentals of Excimer Laser Photoablation
- •Types of Photoablating Lasers
- •Corneal Wound Healing
- •2 Patient Evaluation
- •Patient History
- •Patient Expectations
- •Social History
- •Medical History
- •Pertinent Ocular History
- •Patient Age, Presbyopia, and Monovision
- •Examination
- •Uncorrected Visual Acuity and Manifest and Cycloplegic Refraction
- •Pupillary Examination
- •Ocular Motility, Confrontation Fields, and Ocular Anatomy
- •Intraocular Pressure
- •Slit-Lamp Examination
- •Dilated Fundus Examination
- •Ancillary Tests
- •Corneal Topography
- •Pachymetry
- •Wavefront Analysis
- •Calculation of Residual Stromal Bed Thickness After LASIK
- •Discussion of Findings and Informed Consent
- •3 Incisional Corneal Surgery
- •Incisional Correction of Myopia
- •Radial Keratotomy in the United States
- •Incisional Correction of Astigmatism
- •Coupling
- •Arcuate Keratotomy and Limbal Relaxing Incisions
- •Instrumentation
- •Surgical Techniques
- •Outcomes
- •Complications
- •Ocular Surgery After Arcuate Keratotomy and Limbal Relaxing Incisions
- •4 Onlays and Inlays
- •Keratophakia
- •Homoplastic Corneal Inlays
- •Alloplastic Corneal Inlays
- •Epikeratoplasty
- •Intrastromal Corneal Ring Segments
- •Background
- •Instrumentation
- •Technique
- •Outcomes
- •Intacs and Keratoconus
- •One or Two Intacs Segments?
- •Complications
- •Ectasia After LASIK
- •Uses for Intrastromal Corneal Ring Segments After LASIK
- •Orthokeratology
- •5 Photoablation: Techniques and Outcomes
- •Excimer Laser
- •Background
- •Surface Ablation
- •LASIK
- •Wavefront-Optimized and Wavefront-Guided Ablations
- •Patient Selection for Photoablation
- •Special Considerations for Surface Ablation
- •Special Considerations for LASIK
- •Surgical Technique for Photoablation
- •Calibration of the Excimer Laser
- •Preoperative Planning and Laser Programming
- •Preoperative Preparation of the Patient
- •Preparation of the Bowman Layer or Stromal Bed for Excimer Ablation
- •Application of Laser Treatment
- •Immediate Postablation Measures
- •Postoperative Care
- •Refractive Outcomes
- •Outcomes for Myopia
- •Outcomes for Hyperopia
- •Wavefront-Guided and Wavefront-Optimized Treatment Outcomes for Myopia and Hyperopia
- •Re-treatment (Enhancements)
- •6 Photoablation: Complications and Adverse Effects
- •General Complications Related to Laser Ablation
- •Overcorrection
- •Undercorrection
- •Optical Aberrations
- •Central Islands
- •Decentered Ablations
- •Corticosteroid-Induced Complications
- •Central Toxic Keratopathy
- •Infectious Keratitis
- •Complications Unique to Surface Ablation
- •Persistent Epithelial Defects
- •Sterile Infiltrates
- •Corneal Haze
- •Complications Unique to LASIK
- •Microkeratome Complications
- •Epithelial Sloughing or Defects
- •Flap Striae
- •Traumatic Flap Dislocation
- •LASIK-Interface Complications
- •Visual Disturbances Related to Femtosecond Laser LASIK Flaps
- •Ectasia
- •Rare Complications
- •7 Collagen Shrinkage and Crosslinking Procedures
- •Collagen Shrinkage
- •History
- •Laser Thermokeratoplasty
- •Conductive Keratoplasty
- •Collagen Crosslinking
- •8 Intraocular Refractive Surgery
- •Phakic Intraocular Lenses
- •Background
- •Advantages
- •Disadvantages
- •Patient Selection
- •Surgical Technique
- •Outcomes
- •Complications
- •Refractive Lens Exchange
- •Patient Selection
- •Surgical Planning and Technique
- •IOL Power Calculations in Refractive Lens Exchange
- •Complications
- •Advantages
- •Disadvantages
- •Monofocal Intraocular Lenses
- •Toric Intraocular Lenses
- •Patient Selection
- •Planning and Surgical Technique
- •Outcomes
- •Complications Specific to Toric IOLs
- •Light-Adjustable Intraocular Lenses
- •Accommodating Intraocular Lenses
- •Multifocal Intraocular Lenses
- •Patient Selection
- •Surgical Technique
- •Outcomes
- •Adverse Effects, Complications, and Patient Dissatisfaction with Multifocal IOLs
- •Bioptics
- •Introduction
- •Theories of Accommodation
- •Nonaccommodative Treatment of Presbyopia
- •Monovision
- •Conductive Keratoplasty
- •Multifocal IOL Implants
- •Custom or Multifocal Ablations
- •Corneal Intrastromal Femtosecond Laser Treatment
- •Corneal Inlays
- •Accommodative Treatment of Presbyopia
- •Scleral Surgery
- •Femtosecond Lens Relaxation
- •Accommodating IOLs
- •Other IOL Innovations on the Horizon
- •10 Refractive Surgery in Ocular and Systemic Disease
- •Introduction
- •Ocular Conditions
- •Ocular Surface Disease
- •Herpesvirus Infection
- •Keratoconus
- •Post–Penetrating Keratoplasty
- •Ocular Hypertension and Glaucoma
- •Retinal Disease
- •Amblyopia and Strabismus in Adults and Children
- •Systemic Conditions
- •Human Immunodeficiency Virus Infection
- •Diabetes Mellitus
- •Connective Tissue and Autoimmune Diseases
- •11 Considerations After Refractive Surgery
- •IOL Calculations After Refractive Surgery
- •Eyes With No Preoperative Information
- •The ASCRS Online Post-Refractive IOL Power Calculator
- •Retinal Detachment Repair After LASIK
- •Corneal Transplantation After Refractive Surgery
- •Contact Lens Use After Refractive Surgery
- •Indications
- •General Principles
- •Contact Lenses After Radial Keratotomy
- •Contact Lenses After Surface Ablation
- •Contact Lenses After LASIK
- •Glaucoma After Refractive Surgery
- •12 International Perspectives in Refractive Surgery
- •Introduction
- •Global Estimates of Refractive Surgery
- •International Trends in Refractive Surgery
- •Basic Texts
- •Related Academy Materials
- •Requesting Continuing Medical Education Credit
In the case of a patient with high hyperopia, biometry may suggest an IOL power beyond what is commercially available. The upper limit of commercially available IOL power is now +40.00 D. A special-order IOL of a higher power may be available or may be designed, but acquiring or designing such a lens usually requires the approval of the institutional review board at the hospital or surgical center, which delays the surgery. Another option is to use a “piggyback” IOL system, in which 2 posterior chamber IOLs are inserted. One IOL is placed in the capsular bag, and the other is placed in the ciliary sulcus. When piggyback IOLs are used, the combined power may need to be increased +1.50 to +2.00 D to compensate for the posterior shift of the posterior IOL. One serious complication of piggyback IOLs is the potential for developing an interlenticular opaque membrane. These membranes cannot be mechanically removed or cleared with the Nd:YAG laser; the IOLs must be removed. Interlenticular membranes have occurred most commonly between 2 acrylic IOLs, especially when both IOLs are placed in the capsular bag. When piggyback lenses are used, they should be of different materials and the fixation should be split between the bag and the sulcus. Piggyback IOLs may also shallow the anterior chamber and increase the risk of iris chafing, especially in smaller eyes.
Hill WE, Byrne SF. Complex axial length measurements and unusual IOL power calculations. Focal Points: Clinical Modules for Ophthalmologists. San Francisco: American Academy of Ophthalmology; 2004, module 9.
Shammas HJ. IOL power calculation in patients with prior corneal refractive surgery. Focal Points: Clinical Modules for Ophthalmologists. San Francisco: American Academy of Ophthalmology; 2013, module 6.
Complications
At more than 2 years postoperatively, the incidence of retinal detachment in 1519 consecutive patients (2356 eyes) with an axial length greater than 27.0 mm was reported to be 1.5%–2.2%, a level that corresponds to the incidence of idiopathic retinal detachment in myopia.
Horgan N, Condon PI, Beatty S. Refractive lens exchange in high myopia: long term follow up. Br J Ophthalmol. 2005;89(6):670–672.
Neuhann IM, Neuhann TF, Heimann H, Schmickler S, Gerl RH, Foerster MH. Retinal detachment after phacoemulsification in high myopia: analysis of 2356 cases. J Cataract Refract Surg. 2008;34(10):1644–1657.
Advantages
Refractive lens exchange has the advantage of greatly expanding the range of refractive surgery beyond what can be achieved with other available methods. The procedure retains the normal contour of the cornea, which may enhance the quality of vision, and it may be used to treat presbyopia as well as refractive error with incorporation of multifocal and/or accommodating IOLs.
Disadvantages
Quality of vision may not be as good with current multifocal IOLs as with other forms of vision correction. Patient expectations for excellent uncorrected visual acuity may be higher for RLE than for cataract surgery, underscoring the need for thorough preoperative discussion, close attention to detail preoperatively and intraoperatively, and postoperative treatment of residual refractive error.
Monofocal Intraocular Lenses
For some patients, the best IOL choice for implantation at the time of RLE is a monofocal IOL. There are a variety of IOL choices and styles available, and all are utilized in routine cataract surgery as well (see BCSC Section 11, Lens and Cataract, for more detail). Patients without significant corneal
