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CHAPTER 1

Introduction to Glaucoma: Terminology, Epidemiology, and Heredity

Definitions

Glaucoma represents a group of diseases defined by a characteristic optic neuropathy that is consistent with excavation and undermining of the neural and connective tissue elements of the optic disc and by the eventual development of distinctive patterns of visual dysfunction. Although elevated intraocular pressure (IOP) is one of the primary risk factors, its presence or absence does not have a role in the definition of the disease. Normal aqueous humor flow in the eye is illustrated in Figure 1- 1.