epithelial cells, malignant goblet cells can be shown with mucin stains. Mucoepidermoid carcinoma is more likely than squamous cell carcinoma to invade the globe or orbit. Treatment is wide surgical excision; adjuvant therapy can include cryotherapy and radiotherapy.

Spindle cell carcinoma

Spindle cell carcinoma is a rare, highly malignant tumor of the bulbar or limbal conjunctiva in which the anaplastic cells appear spindle shaped, like fibroblasts.

Glandular Tumors of the Conjunctiva

Oncocytoma

A slow-growing cystadenoma, an oncocytoma arises from ductal and acinar cells of main and accessory lacrimal glands. In older individuals, an oncocytoma may present as a reddish brown nodule on the surface of the caruncle.

Sebaceous Gland Carcinoma

Sebaceous gland carcinomas account for approximately 1% of all eyelid tumors and 5% of eyelid malignancies. They affect older individuals but may be seen in younger individuals after radiation therapy. They may masquerade as chalazia or as chronic unilateral blepharoconjunctivitis (Fig 8-6). See also BCSC Section 7, Orbit, Eyelids, and Lacrimal System.