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348 Ferenc Kuhn

Hypotony is a statistically significantly strong indicator of open globe injury; a low IOP makes the presence of a full-thickness wound likely [2].

ZCave

Normal or even elevated IOP does not preclude the possibility that an open globe injury has occurred.

Injury type Instant complications

Complications

Complications after

 

within weeks

months or years

Contusion

+ / − (“+” includes lens

 

dislocation, vitreous hem-

 

orrhage, retinal necrosis,

 

or choroidal rupture)

− / + (“+” is usually glaucoma)

+ / − (“+” includes cataract, retinal tear and detachment)

Rupture

+++ (e.g., tissue extru-

+ (e.g., cataract

+ (e.g., PVR)

 

sion, vitreous hemor-

progression, retinal

 

 

rhage)

tear and detach-

 

 

 

ment)

 

Penetrating

++ (e.g., cataract, vitre-

+ / − (“+” includes

− / + (“+” is usually

 

ous hemorrhage, retinal

cataract, retinal tear

PVR)

 

laceration)

and detachment)

 

IOFB

++ (e.g., cataract, vitre-

+ / − (“+” includes

− / + (“+” is usually

 

ous hemorrhage, retinal

cataract, retinal tear

PVR or metallosis)

 

laceration)

and detachment)

 

Perforating

++ (e.g., cataract, vitre-

+ / − (“+” includes

++ / − (“+” is usually

 

ous hemorrhage, retinal

cataract, retinal tear

PVR)

 

laceration)

and detachment,

 

 

 

PVR)

 

Reflecting typical cases; individual exceptions always occur

  2.11  Open Globe Injury: a Brief Overview

349

Once it has been determined that the eye has a full-thickness defect (see Chap. 2.10) requiring closure, the standard evaluation process should be limited (Fig. 2.12.2) to obtaining information that affects the timing or the type of the primary intervention:

Risk of ECH (Chap. 2.8)

Risk of endophthalmitis (see Chap. 2.17)

Presence of an IOFB (see Chap. 2.13)

Probability of a perforating injury (see Chap. 2.14)

The patient’s systemic condition as this concerns surgery and anesthesia (see Chap. 1.8)

It is important to also look for adnexal and orbital injuries: they are present in 26% of open globe injuries, increasing the risk of posterior segment injury and poor outcome [1].

2.11.3Management

In this chapter only a brief overview is given (Table 2.11.2); see Chaps. 1.8, 2.12−2.15, and 2.17−2.20 for details. A few additional issues are discussed below:

As described in Chap. 1.8, treatment of a patient with an open globe injury must not be a mechanical, one-by-one restoration of tissue pathologies. If a corneal wound and a hyphema are present, the goal is not to introduce sutures until the wound is watertight and wait until the hyphema clears. The surgeon must first design a strategic plan, which answers the overall questions, and then a tactical plan, which answers

i.e., the wound is not self-sealing

e.g., Is surgery urgent? Is there a posterior scleral extension of the corneal wound? Is the risk of endophthalmitis high? Is an ECH imminent? Is the IOP high? Is there vitreous prolapse into the AC? Is there a lens injury? Is there injury to the posterior segment?

350

Ferenc Kuhn

 

Table 2.11.2  Management issues in eyes with open globe injury.1

Variable

Comment

History

 

Find out what happened and how (the injury’s circumstances)

 

 

Determine whether the agent was likely to have been contami-

 

 

nated

 

 

Find out when the incident occurred

 

 

Determine whether the injury occurred at the workplace, and if

 

 

so, whether a report has been filed

 

 

Determine if the injury was self-inflicted or the result of assault

 

 

Determine if a witness can be identified1

 

 

Determine the object’s size, material, and whether it is likely to

 

 

have been retained intraocularly

 

 

Ask about vision and pain as the injury occurred, and how these

 

 

symptoms have changed since then

 

 

Determine whether someone has already seen/treated the pa-

 

 

tient, who that person was, and what therapy has been applied

 

 

Ask when the patient took something orally, and if yes, what

 

 

and when

Visual acuity

Always take it in the injured eye; there is no need to refract if the

 

 

patient wears glasses and they are unavailable: use a pinhole

 

 

and note its use in the patient’s chart

 

 

Always take it in the fellow eye

 

 

If a standard visual acuity chart is unavailable, use a near chart

 

 

or even your fingers (see Chap. 1.8)

External inspection

Using a penlight, compare the two eyes2 and note all major

 

 

abnormalities. A shallow AC may be easier to diagnose this way

 

 

than with a slit lamp where simultaneous visualization of the

 

 

two eyes (comparison) is not possible

1 See also Chaps. 1.8 and 1.9.

 

  2.11  Open Globe Injury: a Brief Overview

351

Table 2.11.2  (continued) Management issues in eyes with open globe injury.

 

Variable

Comment

 

Slit lamp

Never put pressure on the eye when separating the lids; if the

 

 

lids are impossible to open because of hemorrhage, delay the

 

 

examination and keep an icepack over the lids to expedite the

 

 

resolution of the blood and edema

 

 

Meticulously examine the lids, cornea, conjunctiva, sclera, and

 

 

the anterior segment

 

 

Be wary of thick subconjunctival hemorrhages, which may hide

 

a scleral wound underneath

 

 

Carefully examine the pupils and their reaction, including the

 

 

presence or absence of an APD

 

 

Take the IOP unless a large and central corneal wound is present

Ophthalmoscopy

Try to examine as much of the retina as possible (Fig. 2.11.1)

 

 

Do not use scleral indentation

 

 

Dilate the pupil unless there is a contraindication3

 

Ultrasonography

If felt necessary and if the wound is not leaking, very careful

 

and radiological

B-scan ultrasonography may be attempted; however, it is usu-

 

examinations

ally preferable to perform the examination in the OR after the

 

 

wound has been closed

 

The primary goals of CT are to detect an IOFB or the presence of an occult or posterior scleral wound; it can also show orbital pathologies such a fracture

If presence of a nonmetallic IOFB is suspected, an MRI may be indicated; it can also supply more detailed information on soft tissue injuries

Exploratory surgery: if still uncertain whether an occult rupture is present, the conjunctiva over the hemorrhage should be opened

352 Ferenc Kuhn

Table 2.11.2  (continued) Management issues in eyes with open globe injury.

Variable

Comment

Decision making: questions to be answered by the attending ophthalmologist (strategy; see Chap. 1.8)

Primary (emergency) surgery5 (tactics; see Chaps. 2.1−2.20)

Is it certain that a full-thickness wound is present?

Can an occult rupture be excluded?

Is an IOFB present?

Is this a high-risk injury for endophthalmitis?

Can surgery be delayed until general anesthesia becomes available?

Are prophylactic intravitreal antibiotics necessary?

Does this injury require more manipulations during the primary surgery than wound toilette and closure?

Triple “E”: Am I capable to properly deal with the complications that are present or may be found during wound closure and need immediate action (expertise, experience)? Is the facility I am to operate at able to provide the required OR personnel and materials for me to do an optimal job (equipment)?

Shall I aim for a staged approach or perform comprehensive surgery instead?

Is it preferable to refer this patient to a colleague who is more likely to do an optimal surgery?

If yes, would the patient arrive there within a reasonably short time?

Is the eye’s condition likely to worsen4 during transportation?

Before referral, try to communicate with the colleague directly

Wound toilette: make sure no vitreous is left external to the wound, in-between the wound lips, and, if possible, behind (underneath) the wound (vitrectomy must be accomplished in the AC and at least attempted at a scleral wound)

Wound closure

AC cleansing as necessary

Lens extraction as necessary

Intravitreal antibiotics/corticosteroids as necessary

 

  2.11  Open Globe Injury: a Brief Overview

353

Table 2.11.2  (continued) Management issues in eyes with open globe injury.

 

Variable

Comment

 

Postoperative

Triple “I”: topical or even systemic medications against infection,

medical treatment

inflammation, IOP elevation

 

Secondary (recon-

Determine how long hospitalization is necessary6

 

structive) surgery

Determine whether, and, if yes, when, a reoperation is required

 

 

Determine whether this second surgery should be performed

 

by you or the patient should be referred (see above)

 

If the surgery is to be performed by you, make sure that all

 

conditions are optimal at the time of the operation7

 

Report the case to the eye injury database

 

Make sure that the patient has proper follow-up and that the

 

final data8 are also registered in the database

1 This is especially important in children (see Chap. 2.16) or if the injury is likely to lead to a legal claim (see Chap. 1.8).

2  Look for differences even if both eyes have been injured.

3  Even the history of an acute angle closure glaucoma in the fellow eye and the lack of prophylactic iridectomy in the injured eye is not an absolute contraindication; give oral acetazolamide before dilating. Conversely, do not dilate the pupil if head injury occurred. The pupillary reaction is crucial for the neurosurgeon to examine.

4 The condition may worsen on its own or because of the patient’s action (e.g., rubbing of the eye).

5 This reflects a staged approach.

6  Medical as well as societal and financial considerations must be taken into account.

7  As mentioned earlier (see Chap. 1.8), this includes, among others, equipment (e.g., vitrectomy machine); materials (e.g., silicone oil, IOL), and personnel (OR nurse, assistant). It is also advisable to schedule the case so that it does not put undue pressure on the OR personnel in terms of overtime and that interference with elective cases be minimized. You should antagonize neither your nurses nor your colleagues.

8  Six months are often too short for “final” data in eyes with severe injury: years may pass before it can be determined that the eye’s condition, as related to the injury, is safely considered permanent.

354 Ferenc Kuhn

Fig. 2.11.1  Vitreous hemorrhage and retinal inspection. This eye sustained an open globe injury caused by a nail. Despite the vitreous hemorrhage, it is possible to examine much of the retina with the ophthalmoscope

the technical questions . Without such planning, management is bound to be suboptimal.

ZPearl

Surgery for an eye with open globe surgery should be delayed for a few minutes so that the most appropriate management plan can be designed. Such a delay does not pose any risk; going to surgery without such a plan does.

In many institutions it is the OR nurse who prepares the eye for surgery. If the eye has an open globe injury, the eye should always be prepared by the ophthalmologist (Fig. 1.8.16, 2.8.2). The surgeon is more likely to be fully aware of the ECH risk and avoid increasing it by unintentionally exerting pressure on the globe.

e.g., How many sutures? What order? How many paracenteses to irrigate the AC?

Includes betadine use, draping, even placement of a lid speculum.

  2.11  Open Globe Injury: a Brief Overview

355

Suturing the cornea and the sclera have very difficult requirements and goals, and demand the use of different tools and technology; these are described in Chaps. 2.2 and 2.3. A brief comparative review of the management of corneal vs scleral wounds is provided in Table 2.11.3.

The need for antibiotic therapy, the routes of administration, and the type and dose of the drugs must be carefully considered, as must the use of corticosteroids (see Chaps. 1.8, 2.17).

Table 2.11.3  Management of corneal and scleral wounds: a comparison

Variable

Cornea

Sclera

Goal: maintain/restore

+++

clarity of tissue

 

 

Goal: maintain/restore

+++

+ / (“-“ if wound too posterior

shape of tissue/globe

 

and closure risks tissue extru-

 

 

sion)

Goal: watertight wound

+++

+++/- (“-” if wound too posterior

 

 

and closure risks tissue extrusion

Sequence

Inward/halving/run-

Antero-posterior/halving

 

ning

 

Suture material

Nonabsorbable

Absorbable/nonabsorbable

Suture size

10/0

6/0 to 8/0

Suture removal

After at least a 3-month

 

waiting period

 

Handling of prolapsed

Depending on the type

tissue

of tissue, reposit, or

 

excise

Detailed evaluation if

wound easily visible

 

Depending on the type of tissue, reposit or excise; if wound too posterior, leave

Detailed evaluation if

+

+++ to determine whether a

wound not visible

 

wound is present (occult rupture)

Best method to evaluate

Slit lamp; fluorescein

Slit lamp; CT; ultrasonography

 

(rose bengal) staining

 

356 Ferenc Kuhn

Table 2.11.3  (continued) Management of corneal and scleral wounds: a comparison

Variable

Cornea

Sclera

Injury type

Contusion/concussion

Contusion/concussion uncom-

 

common

mon

 

Epicorneal FB

Episcleral FB very uncommon;

 

very common

 

 

Intracorneal FB

Intrascleral FB uncommon

 

uncommon

 

 

Rupture uncommon

Rupture relatively common

 

Laceration common

Laceration common

Significance of previous

+++

+

surgery (wound dehis-

 

 

cence/rupture)

 

 

Symptoms of injury

Pain

Bleeding

 

Photophobia

 

 

Lacrimation

 

Wound must always be

+++ / −

See above

closed

 

 

See Chaps. 2.2 and 2.3 for further details

DO:

evaluate the eye as dictated by the specific injury, not simply by following a protocol

design a plan, both in terms of strategy and tactics, before initiating treatment

DON’T:

let an assistant prepare the eye for surgery; this needs to be done by you, the surgeon

follow instincts during surgery, but try to think logically and follow-up this logic with your actions

  2.11  Open Globe Injury: a Brief Overview

357

Summary

Open globe injuries present several serious risks not associated with contusion, even if many of the pathologies caused by the two types of trauma are similar or identical. Paradoxically, taking a few minutes to

design a management plan is more important for eyes with open than with closed globe injury, despite the relative urgency to close the wound.

References

[1]Hatton MP, Thakker MM, Ray S (2002) Orbital and adnexal trauma associated with open-globe injuries. Ophthal Plast Reconstr Surg 18: 458−461

[2]Lima-Gomez V, Cornejo-Mendoza AM (2004) Value of ocular hypotony as a predictor of open-globe injury in patients with ocular trauma. Circulation 72: 177−181 [in Spanish]

[3]Thompson JT, Parver LM, Enger CL, Mieler WF, Liggett PE (1993) Infectious endophthalmitis after penetrating injuries with retained intraocular foreign bodies. Ophthalmology 100: 1468−1474

[4]Thompson W, Rubsamen P, Flynn H, Schiffman J, Cousins S (1995) Endophthalmitis after penetrating trauma. Risk factors and visual acuity outcomes. Ophthalmology 102: 1696−1701