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Ординатура / Офтальмология / Учебные материалы / Clinical Strategies in the Management of Diabetic Retinopathy Springer.pdf
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Diabetic Macular Edema

3

 

Francesco Bandello, Ilaria Zucchiatti, Rosangela Lattanzio,

and Chiara Preziosa

Contents

3.1

Clinical Overview .........................................................................................................

66

 

3.1.1

Clinical Findings.............................................................................................

66

 

3.1.2 Biomicroscopic Classification of DME ..........................................................

67

3.2

Diagnostic Tools............................................................................................................

71

 

3.2.1

Fluorescein Angiography................................................................................

71

 

3.2.2

Optical Coherence Tomography .....................................................................

74

 

3.2.3

Fundus Photography .......................................................................................

77

 

3.2.4

Microperimetry ...............................................................................................

77

 

3.2.5

Multifocal Electroretinogram..........................................................................

78

 

3.2.6 Other Imaging Under Investigation.................................................................

78

3.3

Present Therapies ..........................................................................................................

79

 

3.3.1

Laser Photocoagulation...................................................................................

79

 

3.3.2

Intravitreal Pharmacotherapies .......................................................................

85

 

3.3.3

Pars Plana Vitrectomy.....................................................................................

101

3.4

Evolving Algorithms.....................................................................................................

104

 

3.4.1

Therapeutic Algorithms ..................................................................................

104

 

3.4.2 Factors Associated with Favorable Response to the Therapy.........................

107

 

3.4.3 Treatment of DME Associated with Macular Ischemia..................................

107

3.5

New Frontiers................................................................................................................

111

References....................................................................................................................

............

113

F. Bandello, MD, FEBO (*) • I. Zucchiatti, MD • R. Lattanzio, MD • C. Preziosa, MD Department of Ophthalmology, University Vita-Salute,

Scientific Institute San Raffaele, via Olgettina 60, Milan 20132, Italy e-mail: bandello.francesco@hsr.it; ilaria.zucchiatti@gmail.com; lattanzio.rosangela@hsr.it; preziosachiara@gmail.com

F. Bandello et al. (eds.), Clinical Strategies in the Management of Diabetic Retinopathy,

65

DOI 10.1007/978-3-642-54503-0_3, © Springer-Verlag Berlin Heidelberg 2014