- •Vorwort zur 3. Auflage
- •Inhaltsverzeichnis
- •Abkürzungsverzeichnis
- •Autorenverzeichnis
- •1 Epidemiologie der AMD
- •1.1 Klassifikation
- •1.2 Häufigkeit
- •1.2.1 Prävalenz
- •1.2.2 Inzidenz
- •1.3 Natürlicher Verlauf
- •1.4 Genetische Faktoren
- •1.4.1 Gene des Komplementsystems
- •1.4.2 ARMS2-Lokus (10q26)
- •1.4.3 Gene des Lipidmetabolismus
- •1.5 Umweltfaktoren
- •1.5.1 Rauchen
- •1.5.2 Antioxidanzien
- •1.5.3 Body-Mass-Index
- •1.5.4 Hypertonie
- •1.5.5 Kataraktchirurgie
- •1.6 Interaktion zwischen Risikofaktoren
- •Literatur
- •2 Genetik
- •2.1 Einleitung
- •2.3 Frühe Erkenntnisse
- •2.3.1 ABCA4-Gen
- •2.4.1 Funktionelle Implikationen
- •Literatur
- •3 Alterung der Netzhaut und des retinalen Pigmentepithels*
- •3.1 Einleitung
- •3.2 Ursache und Folgen des Alterns
- •3.4 Alterung der Neuroretina
- •3.5.3 Akkumulation von Lipofuszin
- •Literatur
- •4 Das Komplementsystem bei der AMD
- •4.1 Einleitung
- •4.2 Das Komplementsystem
- •4.6 Schlussfolgerung
- •Literatur
- •5 Histopathologie
- •5.1 Retinales Pigmentepithel
- •5.2 Bruch-Membran
- •5.2.1 Aufbau der Bruch-Membran
- •5.3 Chorioidale Neovaskularisation
- •Literatur
- •6.1 Einleitung
- •6.2 Drusen
- •6.4 Störungen der Aderhautperfusion
- •Literatur
- •7 Klinische Manifestationen der choroidalen Neovaskularisation bei AMD
- •7.1 Einleitung
- •7.2.1 Minderung der Sehschärfe
- •7.2.2 Metamorphopsie
- •7.2.3 Gesichtsfeldausfälle
- •7.2.4 Weitere Symptome
- •7.3.1 Blutung
- •7.3.4 Weitere Befunde
- •7.4.1 Fluoreszein-Angiographie
- •7.4.2 Indozyaningrün-Angiographie
- •7.4.3 Autofluoreszenz
- •7.4.4 Optische Kohärenztomographie
- •Literatur
- •8 Geographische Atrophie
- •8.1 Einführung
- •8.2 Klinische Merkmale
- •8.3 Histologie und Pathogenese
- •8.7 Risikofaktoren
- •8.7.1 Genetische Faktoren
- •8.7.2 Systemische Risikofaktoren
- •8.7.3 Okuläre Risikofaktoren
- •8.9.1 Messung der Sehschärfe
- •8.9.2 Kontrastsensitivität
- •8.9.3 Lesegeschwindigkeit
- •8.9.4 Fundusperimetrie
- •8.10 Therapeutische Ansätze
- •8.10.2 Antiinflammtorische Substanzen
- •8.10.3 Komplementinhibition
- •8.10.4 Neuroprotektion
- •8.10.6 Serotonin-1A-Agonist
- •Literatur
- •9 Imaging bei AMD
- •9.1 Einleitung
- •9.2 Farbphotographie
- •9.3 Monochrome Photographie
- •9.4 Autofluoreszenz
- •9.5 Optische Kohärenztomographie
- •9.5.1 Welleneigenschaften des Lichts
- •9.5.2 Kohärenzlänge
- •9.6 Angiographie
- •9.6.5 Fluoreszein-Injektion
- •9.6.6 Fluoreszein-Angiographie
- •9.6.7 Indozyaningrün-Angiographie
- •9.7.1 Drusen
- •9.8 Neovaskuläre AMD
- •9.10 Follow-up
- •9.10.1 Thermischer Laserkoagulation
- •9.10.2 Photodynamische Therapie
- •9.11 Anti-VEGF-Therapie
- •Literatur
- •10 Optische Kohärenztomographie
- •10.1 Einleitung
- •10.4 OCT bei geographischer Atrophie
- •10.5 OCT bei exsudativer AMD
- •Literatur
- •11 Mikroperimetrie
- •11.1 Einleitung
- •11.2 Technische Entwicklung
- •11.2.2 Automatische Mikroperimetrie
- •11.2.4 Mikroperimetrie: Auswertung
- •11.2.5 Weitere Mikroperimeter
- •11.3 Mikroperimetrie bei AMD
- •11.3.2 Geographische Atrophie
- •11.3.3 Neovaskuläre AMD
- •11.3.4 Therapie der neovaskulären AMD
- •Literatur
- •12 Nahrungsergänzung
- •12.1 Einleitung
- •12.2 Antioxidanzien und Zink
- •12.3 β-Carotin
- •12.4 Makuläre Xantophylle
- •12.6 Vitamin E
- •12.7 Vitamin C
- •12.8 Zink
- •12.10 AREDS2
- •Literatur
- •13.1 Einleitung
- •13.2 Grundlagen
- •13.2.1 Klinischer Hintergrund
- •13.2.2 Laserphotokoagulation
- •13.2.3 Photodynamische Therapie
- •13.3 Behandlungsabläufe
- •13.3.1 Laserphotokoagulation
- •13.3.2 Photodynamische Therapie
- •13.4 Studienergebnisse
- •13.4.1 Laserphotokoagulation
- •13.4.2 Photodynamische Therapie
- •13.5.1 Laserphotokoagulation
- •13.5.2 Photodynamische Therapie
- •13.6 Varianten
- •13.6.2 Photodynamische Therapie
- •13.7 Derzeitige Leitlinien
- •13.7.1 Laserphotokoagulation
- •13.7.2 Photodynamische Therapie
- •13.8 Perspektiven
- •14 Anti-VEGF-Therapie: Grundlagen und Substanzen
- •14.1 Einleitung
- •14.2 Vascular endothelial growth factor
- •14.3.1 Sequestrierung von freiem VEGF
- •14.4 Neue Applikationsformen
- •14.5 Kombinationstherapie
- •Literatur
- •15.1 Hintergrund
- •Literatur
- •16 Kombinationstherapien zur Behandlung der AMD
- •16.1 Einleitung
- •Literatur
- •17 Behandlungsansätze bei trockener AMD
- •17.1 Einleitung
- •17.2 Aktuelle Behandlungsmöglichkeiten
- •17.3 Die Ursachen der AMD adressieren
- •17.4.1 Endpunkte klinischer Studien
- •17.4.3 Modulatoren des Sehzyklus
- •17.5 Zusammenfassung
- •Literatur
- •18 Chirurgische Therapie
- •18.1 Makulaplastik
- •18.2 Makulatranslokation
- •18.5 Indikationen zur Chirurgie
- •18.5.1 Non-Responder
- •18.5.2 Pigmentepithelruptur
- •18.5.3 Massive submakuläre Blutung
- •18.5.4 Trockene AMD
- •Literatur
- •19 Lesefähigkeit bei AMD
- •19.1 Einleitung
- •19.2 Physiologische Grundlagen
- •19.3.3 Beurteilung des Fixationsverhaltens
- •19.3.4 Motorik
- •Literatur
- •20 Vergrößernde Sehhilfen bei AMD
- •20.4 Vergrößerungsmöglichkeiten
- •20.8 Elektronische Vorlesegeräte
- •20.9 Ergänzende Hilfsmittel
- •20.11 Grundlagen der Verordnung
- •Literatur
- •Stichwortverzeichnis
Stichwortverzeichnis
|
A |
|
|
|
|
Anthranilamide-Pyridinurea 234 |
– genetische Faktoren |
38, 132 |
|||||||||||
|
|
|
|
|
Anthranilic acid amide 234 |
|
– |
klinische Manifestationen 127 |
|||||||||||
|
|
|
|
|
|
Antiangiogenese |
255 |
|
|
– |
Kontrastsensitivität |
135 |
|||||||
A2E 52, 147, 274 |
|
Anticaline |
233 |
|
|
|
|
– Lesegeschwindigkeit |
135 |
||||||||||
ABCA1-Gen |
18 |
|
|
Antioxidanzien |
19, 21, 71, 196 |
|
– Lichtexposition |
132 |
|
||||||||||
ABCA4-Gen |
18, 35 |
|
Anti-VEGF-Therapie |
163, 172, 227, 237 |
– Quantifizierung |
130 |
|
||||||||||||
Ablagerungen |
|
|
– |
s.a. VEGF-Inhibitoren |
|
|
– |
Risikofaktoren |
132 |
|
|||||||||
– s.a. Drusen |
|
|
|
– Indikationen |
243 |
|
|
– Sehfunktion 134 |
|
|
|||||||||
– basale lineare |
108 |
|
– Kombination mit Verteportin-PDT |
– Spectral-Domain-OCT |
171 |
||||||||||||||
– subretinale drusenartige |
147 |
|
224 |
|
|
|
|
|
|
– Therapie 135 |
|
|
|
||||||
ACU-4429 |
275 |
|
|
– Kontroll-Fluoreszein-Angiographie |
Augenbewegungsregistrierung 300 |
||||||||||||||
Aderhaut, Perfusionsstörung |
111, 188 |
|
163 |
|
|
|
|
|
|
Autofluoreszenz-Bildgebung 147 |
|||||||||
AdPEDF 235 |
|
|
|
– langfristige Ergebnisse |
248 |
|
Autophagie |
53, 54 |
|
|
|||||||||
Advanced glycation end products 83, |
– Leitlinien |
|
240 |
|
|
|
– Ablauf 55 |
|
|
|
|
||||||||
|
92 |
|
|
|
|
– Non-Responder |
226 |
|
|
– Chaparone-mediated |
54 |
||||||||
AG-013958 |
234 |
|
|
– Therapieregime |
244 |
|
|
– lysosomale |
54 |
|
|
|
|||||||
Age-Related-Eye-Disease-Studie 71, |
APC 66 |
|
|
|
|
|
|
|
|
|
|
|
|
||||||
|
196 |
|
|
|
|
APC-Proteine |
68 |
|
|
|
|
|
|
|
|
|
|||
AL-39324 |
234 |
|
|
Apolipoprotein E |
14, 22, 35, 36 |
|
|
B |
|
|
|
|
|||||||
AL-8309A |
137 |
|
|
Arachidonsäure |
92 |
|
|
|
|
|
|
|
|||||||
|
|
|
|
|
|
|
|
|
|
||||||||||
AL-8309B |
274 |
|
|
ARC-1905 |
73, 137, 278 |
|
|
|
|
|
|
|
|
||||||
Alterung |
|
|
|
|
ARED-Studie |
71, 131, 202, 203, 270 |
Barbados-Eye-Studie 7 |
|
|||||||||||
– Bruch-Membran 57, 82 |
|
ARMS2 39 |
|
|
|
|
|
|
Basal laminar deposits 83, 89, 169 |
||||||||||
– |
retinales Pigmentepithel |
50, 81 |
ARMS2-Gen |
12, 21, 71, 106, 107, 132 |
Basal linear deposits |
87 |
|||||||||||||
Amsler-Gitter |
108 |
|
Atrophie, nicht-geographische |
156 |
Beaver-Dam-Eye-Studie |
7, 108, 131, |
|||||||||||||
– modifiziertes |
117 |
|
Atrophie, geographische |
97, 106, 125, |
|
202 |
|
|
|
|
|||||||||
Anaphylatoxine |
67 |
|
|
156, 185, 238 |
|
|
|
|
Bevacizumab |
189, 232, 239, 255, 260, |
|||||||||
Anastomose |
|
|
|
– Body-Mass-Index |
132 |
|
|
|
262, 270 |
|
|
|
|
||||||
– |
chorioretinale |
210 |
|
– |
choroidale Neovaskularisation |
134 |
Bevasiranib |
233 |
|
|
|
||||||||
– |
retinochoroidale 111 |
|
– |
foveale |
107 |
|
|
|
|
Bildschirmlesegerät |
313 |
||||||||
F.G. Holz et al, Altersabhängige Makuladegeneration, DOI 10.1007/978-3-642-20870-6, © Springer-Verlag Berlin Heidelberg 2011
320 Stichwortverzeichnis
Blindheit |
|
127 |
|
|
|
|
|
Chondroitinsulfat |
89 |
|
|
Eicosapentaensäure |
71, 200, 276 |
||||||||||||||
– Definition |
306 |
|
|
|
|
Choriokapillaris |
80, 89, 127 |
|
Eicosanoide |
92 |
|
|
|
|
|
||||||||||||
Blue-Mountains-Eye-Studie |
7, 132, 198 |
|
Chorioretinopathie, zentral seröse |
|
Eingliederungshilfeverordnung |
306 |
|||||||||||||||||||||
Blutung |
|
|
|
|
|
|
|
|
|
120, 157 |
|
|
|
|
|
|
|
Einstärkenlupenbrille |
310 |
|
|||||||
– intraretinale |
118 |
|
|
|
Ciliary neutrophic factor |
137 |
|
Einzelnukleotid-Polymorphismus |
|
||||||||||||||||||
– submakuläre |
288 |
|
|
|
CNTF/NT-501 |
274 |
|
|
35 |
|
|
|
|
|
|
|
|||||||||||
– subretinale |
118, 121, 222 |
|
Coating |
|
286 |
|
|
|
|
|
|
Einzelzellsuspension |
285 |
|
|
||||||||||||
Body-Mass-Index |
19, 69, 132 |
|
Copaxone |
279 |
|
|
|
|
Endostatin |
|
234 |
|
|
|
|
|
|||||||||||
Brachytherapie |
255 |
|
|
|
Copenhagen-City-Eye-Studie 7 |
|
Enhanced-Depth-Imaging-OCT 120 |
||||||||||||||||||||
– epimakuläre |
262 |
|
|
|
C-reaktives Protein |
20 |
|
|
Erblindung |
19, 80, 116, 230, 238, 254, |
|||||||||||||||||
Brimonidin |
137 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
289 |
|
|
|
|
|
|
|
||||
Brimonidintartrat-Implantat |
|
|
|
|
|
|
|
|
|
|
|
|
Erythrozytensedimentationsrate |
20 |
|||||||||||||
– intravitreales |
274 |
|
|
|
|
D |
|
|
|
|
|
|
|
|
|
Everolimus |
234 |
|
|
|
|
|
|||||
Bruch-Membran |
14, 41, 58, 67, 81, 82, |
|
|
|
|
|
|
|
|
|
|
|
Eye Disease Case Control Studie |
200, |
|||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||||
85, 90, 94, 156, 169, 289 |
|
|
|
|
|
|
|
|
|
|
|
|
201 |
|
|
|
|
|
|
|
|||||||
– Ablagerungen |
82, 85, 95, 108, 112, |
|
Degeneration |
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||
203 |
|
|
|
|
|
|
|
|
– s.a. Makuladegeneration |
|
|
|
|
|
|
|
|
|
|
||||||||
– Alterung |
57, 82 |
|
|
|
– retikuläre pigmentöse |
110 |
|
F |
|
|
|
|
|
|
|
||||||||||||
– Aminosäurentransport |
95 |
|
DENALI-Studie |
225, 260 |
|
|
|
|
|
|
|
|
|
||||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||||||
– Anfärbbarkeit |
84 |
|
|
|
Diode, superlumineszente |
168 |
|
|
|
|
|
|
|
|
|
||||||||||||
– Aufbau |
81 |
|
|
|
|
|
Disposable-Soma-Theorie 53 |
|
Falte, chorioretinale |
120 |
|
|
|||||||||||||||
– Di usionsstörung |
34, 41 |
|
Docosahexaensäure |
71, 85, 200, 275 |
|
FAM-Studie |
130 |
|
|
|
|
|
|||||||||||||||
– Fettsäurenzusammensetzung 85 |
|
Dreifachtherapie |
261 |
|
|
FBLN6-Gen |
18 |
|
|
|
|
|
|||||||||||||||
– Kollagenänderungen 82 |
|
Drusen |
47, 85, 106, 155 |
|
|
FCFD4514S |
73, 278 |
|
|
|
|
||||||||||||||||
– Lipideinlagerungen |
41, 84, 95, 203 |
|
– |
Anfärbbarkeit |
85 |
|
|
|
Fenretinid |
|
136, 275 |
|
|
|
|
||||||||||||
|
|
|
|
|
|
|
|
|
– basale laminale |
70, 107 |
|
Fenton-Reaktion |
53 |
|
|
|
|
||||||||||
|
|
|
|
|
|
|
|
|
– |
bilaterale |
|
107 |
|
|
|
|
Fernrohrlupenbrille |
312 |
|
|
|||||||
C |
|
|
|
|
|
|
|
|
– |
di use |
107 |
|
|
|
|
|
Fernsehen, Hilfsmittel |
309 |
|
||||||||
|
|
|
|
|
|
|
|
– fokale |
|
106, 107 |
|
|
|
Fettsäurenmetabolismus |
93 |
|
|||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||
|
|
|
|
|
|
|
|
|
– |
große |
|
155 |
|
|
|
|
|
Fibrose, subretinale |
106 |
|
|
||||||
C1-INH |
279 |
|
|
|
|
|
|
– |
harte |
|
7, 87, 107, 108 |
|
|
Fibulin-5 |
18 |
|
|
|
|
|
|||||||
C2-Gen |
10, 39 |
|
|
|
|
|
– Kalzifikation |
110 |
|
|
|
Filling-in-Phänomen 188 |
|
|
|||||||||||||
C3-Gen |
11 |
|
|
|
|
|
|
– Klassifikation |
107 |
|
|
Fine matrix mapping |
135, 186 |
|
|||||||||||||
CABERNET-Studie |
263 |
|
|
– kleine |
|
155 |
|
|
|
|
|
Fixation |
|
|
|
|
|
|
|
||||||||
Carboxyethylpyrrole |
68 |
|
|
– |
kutikuläre |
70, 107, 108, 155 |
|
– exzentrische 298 |
|
|
|
|
|||||||||||||||
Carboxymethyllysin 83 |
|
|
– makuläre |
|
183 |
|
|
|
|
– klinische Beurteilung |
300 |
|
|||||||||||||||
Carboxypeptidase |
67 |
|
|
– mittlere |
155 |
|
|
|
|
– überwiegend exzentrische 181 |
|||||||||||||||||
CAREDS |
|
199 |
|
|
|
|
|
– periphere |
|
110 |
|
|
|
|
– überwiegend zentrale |
181 |
|
||||||||||
Cataract and Age-Related Maculopathy |
|
– retikuläre |
|
107, 133, 169 |
|
– zentrale |
|
299 |
|
|
|
|
|
||||||||||||||
Studie |
|
201 |
|
|
|
|
|
– |
Spectral-Domain-OCT 169 |
|
Fixationsort, bevorzugter retinaler |
||||||||||||||||
Cathepsin D |
54 |
|
|
|
|
– Veränderungen |
110 |
|
185 |
|
|
|
|
|
|
|
|||||||||||
CDCV-Hypothese |
35 |
|
|
|
– |
weiche |
7, 83, 87, 107, 108, 169 |
|
Fixationsstabilität |
300 |
|
|
|
||||||||||||||
CDRV-Hypothese |
35 |
|
|
|
Drusen-softening |
110 |
|
|
Fixationsverhalten |
298, 300 |
|
||||||||||||||||
CETP-Gen |
17 |
|
|
|
|
|
Dystrophie |
17, 111, 290 |
|
|
Fluocinolon |
136 |
|
|
|
|
|
||||||||||
CFB-Gen |
|
10, 39 |
|
|
|
|
– |
vitelliforme |
155 |
|
|
|
Fluoreszein |
150 |
|
|
|
|
|
||||||||
CFH-Gen |
|
8, 34, 38, 68, 107, 132, 238 |
|
|
|
|
|
|
|
|
|
|
|
|
Fluoreszein-Angiographie |
120, 121, |
|||||||||||
CFH-Y402H |
8, 21, 68, 71 |
|
|
|
|
|
|
|
|
|
|
|
|
153, 171, 182 |
|
|
|
|
|
||||||||
CFI-Gen |
|
39 |
|
|
|
|
|
|
|
E |
|
|
|
|
|
|
|
|
|
– Exzitationsfilter |
147 |
|
|
|
|||
Cholesterin |
14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
– Makula |
154 |
|
|
|
|
|
|||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||
Cholesterol |
84 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
– Risiken |
152 |
|
|
|
|
|
||||
Cholesteryltransferprotein, plasmati- |
|
Eculizumab |
|
73, 137, 278 |
|
|
Fluoreszein-Leckage |
154 |
|
|
|||||||||||||||||
sches |
|
41 |
|
|
|
|
|
|
EDCCS |
199 |
|
|
|
|
|
|
Flüssigkeit, subretinale |
119 |
|
||||||||
Stichwortverzeichnis |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
321 |
B–L |
||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||
Flüssigkristall-Display-Mikroperimetrie |
|
Hyperhomozysteinämie |
203 |
|
|
|
Kombinationstherapie |
224, 235, 253 |
|
|||||||||||||||||||||
179 |
|
|
|
|
|
|
|
Hyperoxid-Dismutase, mitochondriale |
|
Komplementaktivierung, systemische |
||||||||||||||||||||
FOCUS-Studie |
259 |
|
|
|
|
54 |
|
|
|
|
|
|
|
|
|
|
|
68 |
|
|
|
|
|
|
|
|
||||
Folsäure |
202 |
|
|
|
|
|
Hyperpigmentierung, fokale |
156 |
|
Komplementfaktor |
|
|
|
|
||||||||||||||||
Fresnelscheibe |
309 |
|
|
|
Hypertonie 19 |
|
|
|
|
|
|
|
– H |
67, 238 |
|
|
|
|
|
|
|
|
||||||||
Fundusautofluoreszenz |
128, 136, 182, |
|
Hypofluoreszenz |
|
155 |
|
|
|
|
|
– B |
10, 39 |
|
|
|
|
|
|
|
|
||||||||||
185 |
|
|
|
|
|
|
|
Hypoperfusion, temporäre choroidale |
|
– H |
8, 34, 276 |
|
|
|
|
|
|
|
||||||||||||
Fundusperimetrie |
135, 136, 177, 178, |
|
|
188 |
|
|
|
|
|
|
|
|
|
|
– |
I |
12 |
|
|
|
|
|
|
|
|
|||||
179, 183, 185, 300 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Komplementgene, chorioidale 70 |
||||||||||||||
Fundusphotographie |
180 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Komplementinhibition |
137 |
|
|
||||||||||||
– farbige |
146 |
|
|
|
|
|
I |
|
|
|
|
|
|
|
|
|
|
Komplementkaskade |
18 |
|
|
|||||||||
– monochrome |
146 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Komplementkomponente 2 |
10, 39 |
|
||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||||
Fundusreflex, Verlust |
47 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Komplementkomponente 3 |
10, 39 |
|
||||||||||||
|
|
|
|
|
|
|
|
iCo-007 |
|
234 |
|
|
|
|
|
|
|
|
Komplementsystem |
8, 39, 65, 137, 276 |
|
|||||||||
|
|
|
|
|
|
|
|
Iluvien |
279 |
|
|
|
|
|
|
|
|
– |
Aktivierung |
66 |
|
|
|
|
||||||
G |
|
|
|
|
|
|
|
Imaging |
|
120, 136, 150 |
|
|
|
|
|
– Genvarianten |
68 |
|
|
|
|
|||||||||
|
|
|
|
|
|
|
Imidazo[1,2-A]Pyridine |
234 |
|
|
|
– |
Inhibition |
276 |
|
|
|
|
|
|||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||||
|
|
|
|
|
|
|
|
Immunsystem, angeborenes |
66 |
|
– Regulatoren |
67 |
|
|
|
|
||||||||||||||
Galilei-Fernrohr 308 |
|
|
|
Indozyaningrün |
120, 121, 150, 151, |
|
Komplexe, retinale vaskuläre anomale |
|||||||||||||||||||||||
GAP-Studie |
131 |
|
|
|
|
|
152, 153, 155 |
|
|
|
|
|
|
|
|
161 |
|
|
|
|
|
|
|
|
||||||
GATE-Studie |
137 |
|
|
|
|
Indozyaningrün-Angiographie |
121, |
|
Kontakt-Brachytherapie |
255 |
|
|
||||||||||||||||||
Gefäßanastomosen, retinale 157 |
|
|
153, 182, 242 |
|
|
|
|
|
|
|
Kontrastsensitivität |
135 |
|
|
||||||||||||||||
Genetik |
8, 33, 38, 132, 237 |
|
– |
Interpretation |
155 |
|
|
|
|
|
– |
parafoveale |
300 |
|
|
|
|
|||||||||||||
Gesichtsfeld |
|
|
|
|
|
|
– |
Risiken |
152 |
|
|
|
|
|
|
|
Kortikosteroide |
254 |
|
|
|
|
||||||||
– peripheres |
|
307 |
|
|
|
Inject-and-Extend-Regime 246 |
|
|
Krypton-Gelblaser 212, 223 |
|
|
|||||||||||||||||||
– zentrales |
300 |
|
|
|
|
Injektion, intravitreale |
72, 189, 234, |
|
Krypton-Rotlaser |
212 |
|
|
|
|||||||||||||||||
Gesichtsfeldausfälle 116, 117 |
|
|
288 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||
Glatirameracetat |
279 |
|
|
|
Integrine |
96 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||
Glomerulonephritis, membrano- |
|
iPad 314 |
|
|
|
|
|
|
|
|
|
|
L |
|
|
|
|
|
|
|
|
|||||||||
proliferative |
69 |
|
|
|
Irispigmentepithel |
285 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
Glutathion-S-Transferase-1 57 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||
Grad der Behinderung |
306 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Laserkoagulation |
188, 212, 217 |
|
|||||||||||||
|
|
|
|
|
|
|
|
|
K |
|
|
|
|
|
|
|
|
|
|
– thermische |
161, 221 |
|
|
|
||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Laserphotokoagulation |
161, 209, 214, |
|
|||||||||
H |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
217, 221, 225, 256 |
|
|
|
|
|||||
|
|
|
|
|
|
|
Katalase |
|
56 |
|
|
|
|
|
|
|
|
– Grundlagen |
212 |
|
|
|
|
|||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
|
|
|
|
|
|
|
Kataraktchirurgie |
|
20, 132 |
|
|
|
– |
Indikation |
214 |
|
|
|
|
||||||||||
Halbbrille |
310 |
|
|
|
|
Kepler-Fernrohr |
308 |
|
|
|
|
|
– |
Leitlinien |
225 |
|
|
|
|
|
||||||||||
Hämoxygenase-1 |
56 |
|
|
|
Kindle |
314 |
|
|
|
|
|
|
|
|
– Nebenwirkungen |
221 |
|
|
||||||||||||
HDL-Cholesterin |
17 |
|
|
|
Kohärenzlänge |
149 |
|
|
|
|
|
– Studienergebnisse |
217 |
|
|
|||||||||||||||
Hemicentin-1 |
18 |
|
|
|
|
Kohärenztomographie, optische |
48, |
|
– Wellenlänge |
223 |
|
|
|
|
||||||||||||||||
Heparansulfat |
89 |
|
|
|
|
92, 95, 109, 111, 119, 122, 129, 148, |
|
Lektin-Weg |
18, 66 |
|
|
|
|
|||||||||||||||||
Heparinsulfat |
57 |
|
|
|
|
|
149, 150, 163, 167, 183, 241, 246, 262 |
|
Leseabstand |
308 |
|
|
|
|
||||||||||||||||
Hisayama-Studie |
7 |
|
|
|
– s.a. Spectral-Domain-OCT |
|
|
|
Lesefähigkeit |
295 |
|
|
|
|
||||||||||||||||
Hitzeschockproteine |
57 |
|
|
– s.a. Time-Domain-OCT |
|
|
|
|
– physiologische Grundlagen |
296 |
|
|||||||||||||||||||
HMCN1-Gen |
18 |
|
|
|
|
– Drusen |
111 |
|
|
|
|
|
|
|
– potenzielle |
300 |
|
|
|
|
||||||||||
Homozystein |
|
202 |
|
|
|
– Frequency-Domain-optische |
149 |
|
– Untersuchung |
300 |
|
|
|
|||||||||||||||||
Hornhautreflex |
299 |
|
|
|
– Tiefenauflösung |
150 |
|
|
|
|
– Verbesserung |
301 |
|
|
|
|||||||||||||||
HTRA1-Gen |
12, 40, 132 |
|
|
– Time-Domain-optische |
149 |
|
|
Lesegeschwindigkeit |
135, 300 |
|
||||||||||||||||||||
HTRA1-SNP |
21 |
|
|
|
|
Kohärenzzeit |
149 |
|
|
|
|
|
|
Lesegesichtsfeld |
297 |
|
|
|
||||||||||||
HtrA serine peptidase 1 |
40 |
|
Kollagenderivate |
|
89 |
|
|
|
|
|
Lesepult 315 |
|
|
|
|
|
|
|
||||||||||||
Hyperfluoreszenz |
154 |
|
|
Kollagenveränderungen |
82 |
|
|
|
Lesetechnik |
316 |
|
|
|
|
|
|||||||||||||||
322 Stichwortverzeichnis
Lesetraining |
301 |
– photodynamische Therapie |
Morbus Stargardt 35, 128 |
|||
Leventiner-Krankheit 155 |
– Prävalenz |
4 |
|
– chirurgische Therapie 290 |
||
Linolensäure |
85 |
– Prävention |
41 |
MP1-Mikroperimeter 179 |
||
Lipase, hepatische 41 |
– Progression |
70 |
Muenster-Aging-and-Retina-Studie 19 |
|||
Lipase C |
17 |
|
– Rauchen |
18, 20, 71, 270 |
|
|
LIPC-Gen |
17 |
|
– Risikofaktoren 238 |
|
||
Lipidakkumulation |
58, 83, 85 |
– Sehbehinderung |
|
306 |
|
|
|
|
N |
|
|
|
|
|
||||||||||||
Lipidmetabolismus |
14, 93 |
|
– Spectral-Domain-OCT |
171 |
|
|
|
|
|
|
|
|||||||||||||||
|
|
|
|
|
|
|
|
|
||||||||||||||||||
Lipidperoxidation |
52 |
|
|
|
– späte |
6, 70 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||
Lipidzusammensetzung |
85 |
|
– Therapie 72, 161, 188, 209, 224, 237, |
Nahrungsergänzungsmittel |
195, |
|||||||||||||||||||||
Lipofuszin |
47, 147, 274 |
|
|
253, 254, 289 |
|
|
|
|
|
|
|
270 |
|
|
|
|
|
|||||||||
– Akkumulation |
52, 80, 97, 128, |
– Therapiekontrolle |
|
172 |
|
|
Narbe, disziforme |
90, 94, 106 |
||||||||||||||||||
183 |
|
|
|
|
|
|
|
|
– trockene |
270 |
|
|
|
|
|
|
Natriumfluoreszein |
95 |
|
|||||||
– Bestandteile |
147 |
|
|
|
– – chirurgische Therapie |
283, 289 |
Nd-YAG-Laser 212 |
|
|
|
||||||||||||||||
logMAR-Visus |
|
241 |
|
|
|
|
– Umweltfaktoren |
18 |
|
|
|
Neovaskularisation |
|
|
|
|||||||||||
Luminanztest |
|
179 |
|
|
|
|
– Verlauf |
7 |
|
|
|
|
|
|
|
|
– |
choroidale |
90, 106, 122, 154, 238, |
|||||||
Lupe 310 |
|
|
|
|
|
|
|
|
Makuladystrophie |
|
111 |
|
|
|
|
242 |
|
|
|
|
|
|||||
Lupenbrille |
310 |
|
|
|
|
|
– chirurgische Therapie |
290 |
|
– |
– Ätiologie |
92 |
|
|
|
|||||||||||
Lupus erythematodes |
69 |
|
Makulaödem |
|
117, 119 |
|
|
|
– – Befunde |
118 |
|
|
|
|||||||||||||
Lutein |
18, 19, 71, 137, 198 |
|
– zystoides |
119 |
|
|
|
|
|
|
– |
– Diagnostik |
121 |
|
|
|||||||||||
Lutetiumtexaphyrin |
224 |
|
Makulaplastik |
284 |
|
|
|
|
|
– – Di erenzierung |
|
92 |
|
|||||||||||||
|
|
|
|
|
|
|
|
|
|
Makulatranslokation |
189, 256, 284 |
– |
– extrafoveale |
210, 217 |
|
|||||||||||
|
|
|
|
|
|
|
|
|
|
Makulavolumen |
48 |
|
|
|
|
– – juxtafoveale |
210 |
|
||||||||
M |
|
|
|
|
|
|
|
|
|
Malattia leventinese |
155 |
|
|
– |
– klassische |
92, 210 |
|
|||||||||
|
|
|
|
|
|
|
|
|
Malondialdehyd |
52 |
|
|
|
|
– – okkulte 92, 210 |
|
|
|||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||
|
|
|
|
|
|
|
|
|
|
Matrixmetalloproteinasen |
85 |
– – Pathogenese 156 |
|
|||||||||||||
Macular-Mapping-Test 300 |
|
Matrixproteine, extrazelluläre |
83 |
– |
– polypoide 122 |
|
|
|
||||||||||||||||||
Makroautophagozytose |
54 |
|
MC-1101 |
272 |
|
|
|
|
|
|
|
– – rezidivierende |
161 |
|
||||||||||||
Makula |
|
|
|
|
|
|
|
|
|
Melanin |
147 |
|
|
|
|
|
|
|
– – subfoveale |
186, 210, 218, 242, |
||||||
– Fluoreszein-Angiographie |
154 |
Melanolipofuszin |
53 |
|
|
|
|
256 |
|
|
|
|
|
|||||||||||||
Makuladegeneration, altersabhängige |
Melanosomen |
|
|
|
|
|
|
|
– – Symptome |
116 |
|
|
||||||||||||||
– Alter |
57 |
|
|
|
|
|
|
|
|
– Abnahme |
53 |
|
|
|
|
|
|
– – Therapie |
254 |
|
|
|
||||
– Antioxidanzien |
21, 71, 196 |
– Verlust |
47 |
|
|
|
|
|
|
|
– |
– unilaterale 107 |
|
|
||||||||||||
– Ätiologie |
271 |
|
|
|
|
|
Membran, fibrovaskuläre |
|
90 |
|
– okkulte 220 |
|
|
|
|
|||||||||||
– Body-Mass-Index |
19 |
|
|
Membranextraktion, submakuläre |
– präretinale |
118 |
|
|
|
|||||||||||||||||
– Diagnostik |
241 |
|
|
|
|
285, 288 |
|
|
|
|
|
|
|
|
Nervenfaserschicht, retinale |
48 |
||||||||||
– exsudative |
171, 254 |
|
|
MERITAGE-I-Studie 263 |
|
|
|
Nervus opticus |
147 |
|
|
|
||||||||||||||
– frühe |
6, 105, 183 |
|
|
|
Metalloproteinase-Inhibitor 3 |
17 |
Netzhaut, Alterung |
45, 47, 48 |
||||||||||||||||||
– Frühstadium |
238 |
|
|
|
Metalloproteinasen |
|
41, 83 |
|
Netzhautdicke |
48 |
|
|
|
|||||||||||||
– genetische Faktoren |
|
8, 33 |
|
Metamorphopsie |
116 |
|
|
|
Neuroprotektion |
137, 274 |
|
|||||||||||||||
– Häufigkeit |
4 |
|
|
|
|
|
Mikroautophagozytose |
54 |
|
Neuroretina, Alterung |
48 |
|
||||||||||||||
– Hypertonie |
|
19 |
|
|
|
|
Mikroperimetrie |
117, 136, 177, |
Neutrazimab |
279 |
|
|
|
|||||||||||||
– Imaging |
145 |
|
|
|
|
|
287 |
|
|
|
|
|
|
|
|
|
Normalvergrößerung |
308 |
|
|||||||
– Inzidenz |
7 |
|
|
|
|
|
|
|
– Auswertung |
181 |
|
|
|
|
|
|
|
|
|
|
|
|||||
– Klassifikation |
|
4 |
|
|
|
|
– frühe AMD |
|
183 |
|
|
|
|
|
|
|
|
|
|
|
|
|||||
– klinische Manifestationen |
106 |
– geographische Atrophie |
185 |
|
O |
|
|
|
|
|
||||||||||||||||
– Mikroperimetrie |
183 |
|
|
– kinetische |
180 |
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
– neovaskuläre |
186, 238 |
|
– neovaskuläre AMD |
186 |
|
|
|
|
|
|
|
|
|
|||||||||||||
– nicht-neovaskuläre |
155 |
|
– technische Entwicklung |
178 |
Octadecatriensäure |
85 |
|
|||||||||||||||||||
– operative Therapie |
189 |
|
mitochondriale Dysfunktion |
53 |
Omega-3-Fettsäuren |
|
19, 71, 137, 200, |
|||||||||||||||||||
– Pathogenese |
|
67, 196 |
|
|
MONT-BLANC-Studie |
225, 261 |
|
270, 276 |
|
|
|
|
|
|||||||||||||
– Pathomechanismus |
34 |
|
Morbus Alzheimer |
36 |
|
|
|
OT-551 137, 276 |
|
|
|
|
||||||||||||||
Stichwortverzeichnis |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
323 |
|
L–S |
|||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||
|
|
|
|
|
|
|
|
|
|
Pigmentepithel-Aderhaut-Translokation |
|
Ringskotom |
299 |
|
|
|
|
|
|
||||||||||
P |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
|
|
|
|
|
|
|
|
286 |
|
|
|
|
|
|
|
Risikofaktoren |
4 |
|
|
|
|
|
|
||||||
|
|
|
|
|
|
|
|
|
|
Pigmentepithel, retinales |
45, 80, 81, |
|
– genetische |
|
11, 34, 41, 66, 132 |
|
|
||||||||||||
Palomid 529 234 |
|
|
|
|
85, 90, 94, 97, 111, 119, 159 |
|
– okuläre |
133 |
|
|
|
|
|
|
|
||||||||||||||
Paraoxonase 1 |
18 |
|
|
|
|
– Abhebung |
94, 106, 159 |
|
– systemische |
132 |
|
|
|
|
|
||||||||||||||
Pars-plana-Vitrektomie 262 |
|
– Ablagerungen |
80 |
|
|
|
– umweltbedingte |
20, 41, 66 |
|
|
|||||||||||||||||||
Patch |
286 |
|
|
|
|
|
|
|
– Alterung |
50, 81 |
|
|
|
RN6G |
275 |
|
|
|
|
|
|
|
|
|
|||||
Pazopanib |
|
234 |
|
|
|
|
|
– antioxidative Kapazität |
56 |
|
Rotterdam-Studie |
7 |
|
|
|
|
|
||||||||||||
PDGF |
230 |
|
|
|
|
|
|
|
– Aufbau |
80 |
|
|
|
|
rTPA |
|
|
|
|
|
|
|
|
|
|
|
|||
PEDF |
234 |
|
|
|
|
|
|
|
– Depigmentierung |
20 |
|
|
– intravitreale Injektion |
|
288 |
|
|
||||||||||||
Pegaptanib |
189, 232, 239, 255 |
|
– irreguläre Pigmentierung 106, 111, |
|
– subretinale Injektion |
288 |
|
|
|||||||||||||||||||||
Pentosidine |
83 |
|
|
|
|
183 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||
Perfluorkarbon, flüssiges |
286 |
|
– Riss |
106, 160, 287 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
Perimetrie |
|
135, 136, 177, 178, 179, |
|
– Ruptur s.a. Riss |
|
|
|
|
S |
|
|
|
|
|
|
|
|
|
|
|
|||||||||
183, 185, 300 |
|
|
|
|
|
– Spectral-Domain-OCT |
169 |
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||
– s.a. Mikroperimetrie |
|
|
|
– Zelldichte |
50 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||
– funduskontrollierte |
136 |
|
Pigmentepithelruptur |
287 |
|
Sakkade |
297, 300 |
|
|
|
|
|
|||||||||||||||||
PF-4382923 |
275 |
|
|
|
|
|
PLEKHA1-Gen 12, 39 |
|
|
|
Sauersto , reaktiver |
47, 52 |
|
|
|||||||||||||||
Phospholipide |
92 |
|
|
|
|
PON1-Gen |
18 |
|
|
|
|
Scanning-Laserophthalmoskopie |
109, |
|
|||||||||||||||
photodynamische Therapie 72, 161, |
|
POT-4 |
72, 137, 277 |
|
|
147, 151, 179 |
|
|
|
|
|
|
|
||||||||||||||||
188, 209, 254 |
|
|
|
|
|
Preferential Hyperacuity Perimeter |
|
– konfokale |
128 |
|
|
|
|
|
|
||||||||||||||
– Behandlungstechnik |
216 |
117 |
|
|
|
|
|
|
|
Scatter-Photokoagulation |
219 |
|
|
||||||||||||||||
– Grundlagen |
212 |
|
|
|
|
Proliferation, retinale angiomatöse 70, |
|
sCR1 |
279 |
|
|
|
|
|
|
|
|
|
|||||||||||
– Indikation |
215 |
|
|
|
|
118 |
|
|
|
|
|
|
|
Sehbehinderung |
|
|
|
|
|
|
|||||||||
– Kombination mit Triamcinolon 257 |
|
Protonenbestrahlung |
255 |
|
– Definition |
306 |
|
|
|
|
|
|
|||||||||||||||||
– Kombination mit VEGF-Inhibitoren |
|
Pseudodrusen, retikuläre |
107, 109, |
|
– Einteilung |
307 |
|
|
|
|
|
||||||||||||||||||
259 |
|
|
|
|
|
|
|
147, 156 |
|
|
|
|
|
|
Sehhilfen |
|
|
|
|
|
|
|
|
|
|
||||
– Kontraindikation |
222 |
|
|
|
|
|
|
|
|
|
|
– elektronisch vergrößernde 313 |
|||||||||||||||||
– Leitlinien |
226 |
|
|
|
|
|
|
|
|
|
|
|
|
|
– für die Ferne |
308 |
|
|
|
|
|
||||||||
– Mechanismen |
212 |
|
|
|
Q |
|
|
|
|
|
|
|
– für die Nähe |
309 |
|
|
|
|
|
||||||||||
– Nebenwirkungen |
222 |
|
|
|
|
|
|
|
|
|
– vergrößernde |
301, 305 |
|
|
|||||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||||||
– Studienergebnisse |
|
219 |
|
|
|
|
|
|
|
|
|
– Vergrößerungsbedarf |
|
307 |
|
|
|||||||||||||
Photofrin |
224 |
|
|
|
|
|
Quick-freeze/deep-etch-Technik 84 |
|
– Vergrößerungsmöglichkeiten |
308 |
|
||||||||||||||||||
Photokoagulation |
|
|
|
|
|
Quinazolin-Derivate |
234 |
|
|
– Verordnung |
317 |
|
|
|
|
|
|||||||||||||
– s.a. Laserphotokoagulation |
|
|
|
|
|
|
|
|
|
– Verordnungsfähigkeit |
|
306 |
|
|
|||||||||||||||
– Behandlungstechnik |
214 |
|
|
|
|
|
|
|
|
|
Sehschärfe |
|
|
|
|
|
|
|
|
|
|||||||||
– perifoveale |
218 |
|
|
|
|
R |
|
|
|
|
|
|
|
– Bestimmung |
300 |
|
|
|
|
|
|||||||||
Photorezeptoren |
18, 48, 80, 127, 183, |
|
|
|
|
|
|
|
|
– Messung |
134 |
|
|
|
|
|
|
||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||||
234, 272, 284, 286 |
|
|
|
|
|
|
|
|
|
|
|
|
– Minderung |
116 |
|
|
|
|
|
||||||||||
– Absterben |
94 |
|
|
|
|
|
RADICAL-Studie |
225, 262 |
|
Sehvermögen, zentrales |
|
|
|
|
|||||||||||||||
– Dichte |
48 |
|
|
|
|
|
|
Ranibizumab |
72, 189, 232, 239, 242, |
|
– Verlust |
90 |
|
|
|
|
|
|
|
|
|||||||||
– Transplantation |
284 |
|
255, 263, 270, 287 |
|
|
|
Serotonin-1A-Agonisten 137 |
|
|
||||||||||||||||||||
– Verlust |
272 |
|
|
|
|
|
– Kombination mit PTD |
225 |
|
sFLT01 |
233 |
|
|
|
|
|
|
|
|
|
|||||||||
Photosensitizer 52, 212 |
|
|
Rauchen |
18, 20, 71, 270 |
|
|
Sirolismus |
136 |
|
|
|
|
|
|
|||||||||||||||
Phthalozyanin |
224 |
|
|
|
|
Retina |
18, 47, 50, 58 |
|
|
|
Skotom |
|
|
|
|
|
|
|
|
|
|
||||||||
Physicians’-Health-Studie |
19, 198 |
|
Retinoidsto wechsel |
122 |
|
– absolutes |
185, 187 |
|
|
|
|
||||||||||||||||||
Pigmentepithelabhebung |
94, 119 |
|
Retinotomie |
284 |
|
|
|
– zentrales |
297 |
|
|
|
|
|
|
||||||||||||||
– drusenoide |
169 |
|
|
|
|
– paramakuläre |
286, 288 |
|
SLO-Mikroperimetrie |
185 |
|
|
|||||||||||||||||
– fibrovaskuläre |
119, 127, 157, 171, |
|
– periphere |
288 |
|
|
|
|
Sorsby-Fundusdystrophie |
17, 111 |
|
||||||||||||||||||
210 |
|
|
|
|
|
|
|
|
Retinotopik |
284 |
|
|
|
|
Spectral-Domain-OCT |
120, 129, 149, |
|
||||||||||||
– retinale |
|
159 |
|
|
|
|
|
Rezeptor-Tyrosinkinase-Inhibitoren |
169, 171, 185 |
|
|
|
|
|
|
|
|||||||||||||
– seröse |
111, 120, 243 |
|
234 |
|
|
|
|
|
|
|
– Technik |
168 |
|
|
|
|
|
|
|
||||||||||
324Stichwortverzeichnis
Squalamin 234 Staining 154
Stars-in-the-sky-Erscheinung 108 Strahlentherapie 255
–epiretinale 255
–Kombination mit VEGF-Inhibitoren 262
Stress, oxidativer 47, 52, 68, 137
Studienendpunkte |
271 |
Sudanschwarz 84 |
|
Suszeptibilitätsgene |
36, 38, 39, |
40, 41 |
|
Swept-Source-OCT |
150 |
T
TA106 279
Telebrille 309
Teletherapie 255
TG100801 234
TG101095 234
Thalidomid-Analoga 234
Time-Domain-OCT 149, 184
TIMP3-Gen 17, 41, 85
Tinethyl-Ethiopurpurin 224
Toll-like-Rezeptoren 18, 132
Toxine, retinale 136
Triamcinolon 254, 257
Trimetazidin 272
–Kombination mit Kortikosteroiden und photodynamischer Therapie 261
–Kombination mit photodynamischer Therapie 259
–Kombination mit Strahlentherapie 262
–Komplikationen 256
–natürliche 234
–Non-Responder 287
VEGF-Kaskade |
231 |
|
VEGF-Trap |
233 |
|
Verteporfin |
213, 254, 256, 257 |
|
Verzerrtsehen |
116 |
|
VISION-Studie |
259 |
|
Visual cycle modulators 136 |
||
Vitamin B6 |
202 |
|
Vitamin B12 |
202 |
|
Vitamin C 19, 71, 197, 201 |
||
Vitamin E 19, 56, 71, 197, 201, 270 |
||
Vitrektomie |
262, 288 |
|
Vitronectin |
67 |
|
Vorlesegeräte, elektronische 315
W
WAFACS 203
Women’s Antioxidant and Folic Acid
Cardiovascular Study 203
U |
|
X |
Umweltfaktoren 18 |
|
Xanthophylle, makuläre 198, 203, 212 |
|
|
|
V |
|
Y |
|
|
|
Vaskulopathie, polypoide chorioidale (PCV) 79, 120, 158, 210, 226
VECAT 201
VEGF 94, 230
–Isoformen 230
–Rezeptoren 230
–Sequestrierung 232 VEGF-Gen 18
VEGF-Inhibitoren 72, 231, 255
– s.a. Anti-VEGF-Therapie
Y402H-Gen 20
Z
Zeaxanthin |
18, 19, 71, 137, 198, 203 |
ziliärer neurotropher Faktor 274 Zink 19, 71, 202, 270 Zweistärkenlupenbrille 310
