- •Foreword
- •Preface
- •Glossary
- •1. Introduction
- •2. Historical Considerations
- •2.1 Arteriovenous Fistula and Pulsating Exophthalmos
- •2.2 Angiography
- •2.3 Therapeutic Measures
- •2.4 Embolization
- •References
- •3.1 Osseous Anatomy
- •3.1.1 Orbit
- •3.2 Anatomy of the Dura Mater and the Cranial Nerves
- •3.2.1 Autonomic Nervous System
- •3.3 Vascular Anatomy
- •3.3.1 Arterial Anatomy
- •3.3.1.1 Internal Carotid Artery
- •Meningohypophyseal Trunk (MHT)
- •Ophthalmic Artery
- •Ethmoidal Arteries
- •3.3.1.2 External Carotid Artery
- •3.3.1.2.1 Ascending Pharyngeal Artery
- •3.3.1.2.2 Internal Maxillary Artery
- •3.3.1.2.3 Middle Meningeal Artery
- •3.3.1.2.4 Accessory Meningeal Artery
- •3.3.2 Venous Anatomy
- •3.3.2.1.1 Embryology
- •3.3.2.1.2 Anatomy and Topography
- •Orbital Veins
- •Superior Ophthalmic Vein
- •Inferior Ophthalmic Vein
- •Central Retinal Vein (No Direct CS Tributary)
- •Uncal Vein, Uncinate Vein
- •Sphenoparietal sinus (Breschet), Sinus alae parvae, Sinus sphenoidales superior (Sir C. Bell)
- •Intercavernous Sinus, Sinus intercavernosus, Sinus circularis (Ridley), Sinus ellipticus, Sinus coronarius, Sinus clinoideus (Sir C. Bell), Sinus transversus sellae equinae (Haller)
- •Meningeal Veins
- •Veins of the Foramen Rotundum, Emissary Vein
- •Inferior Petrosal Sinus, Sinus petrosus profundus, Sinus petro-occipitalis superior (Trolard)
- •Venous Plexus of the Hypoglossal Canal, Anterior Condylar Vein
- •Posterior Condylar Vein
- •Lateral Condylar Vein
- •Inferior Petroclival Vein
- •Petro-occipital Sinus, Sinus petro-occipitalis inferior, petro-occipital vein (Padget)
- •Transverse Occipital Sinus (Doyen)
- •Basilar Plexus (Virchow)
- •Marginal Sinus
- •Foramen Ovale Plexus (Trigeminal Sinus), Sphenoid Emissary, “Rete” of the Foramen Ovale
- •Vein of the Sphenoid Foramen (Foramen Venosum, Foramen of Vesalius)
- •Foramen Lacerum Plexus
- •Pterygoid Plexus
- •3.3.2.4 Other Veins of Importance for the CS Drainage or for Transvenous Access to the CS
- •Facial Vein
- •Frontal Vein
- •Angular Vein
- •Middle Temporal Vein
- •Internal Jugular Vein
- •The External Jugular Vein
- •Vertebral Vein, Vertebral Artery Venous Plexus
- •Deep Cervical Vein
- •References
- •Introduction
- •4.1.1 Dural Arteriovenous Fistulas (DAVFs)
- •4.1.2 Cavernous Sinus Fistulas (CSFs)
- •References
- •Introduction
- •5.1 Etiology and Pathogenesis of Type A Fistulas
- •5.2 Etiology and Pathogenesis of Type B–D Fistulas
- •5.2.1 Pregnancy
- •5.2.2 Hormonal Factors
- •5.2.3 Thrombosis
- •5.2.4 Venous Hypertension
- •5.2.5 Trauma
- •5.2.6 Embolization
- •5.2.7 Congenital
- •5.2.8 Other Potential Factors
- •5.2.9 Various
- •5.3 Prevalence
- •5.3.1 Natural History
- •References
- •Introduction
- •6.1 Extraorbital Ocular Symptoms
- •6.1.1 Orbital Pain
- •6.2 Orbital Symptoms
- •6.2.1 Exophthalmos
- •6.2.2 Conjunctival Engorgement and Chemosis
- •6.2.2.1 Retinal Hemorrhage
- •6.2.3 Corneal Damage
- •6.2.4 Orbital Bruit
- •6.2.6 Secondary Glaucoma and Visual Loss
- •6.3 Other and Neurological Symptoms
- •References
- •7. Radiological Diagnosis of DCSFs
- •7.1 Non-invasive Imaging Techniques
- •7.1.2 Doppler and Carotid Duplex Sonography
- •7.2 Intra-arterial Digital Subtraction Angiography (DSA)
- •7.2.1 Introduction
- •7.2.2 Technique
- •7.2.3 Angiographic Protocol for DCSFs
- •7.2.4 Angiographic Anatomy of the Cavernous Sinus
- •7.2.5 Flat Detector Technology in Neuroangiography
- •7.2.6 Rotational Angiography and 3D-DSA
- •7.2.6.1 Dual Volume Technique (DVT)
- •7.2.6.2 Angiographic Computed Tomography (ACT), DynaCT (Siemens), C-arm Flat Detector CT (FD-CT), Flat Panel CT (FP-CT) or Cone Beam CT
- •7.2.6.3 Image Post-Processing
- •7.2.6.4 3D Studies of the Cavernous Sinus Region
- •References
- •8. Endovascular Treatment
- •8.1 Techniques of Transvenous Catheterization
- •8.1.1 Inferior Petrosal Sinus Approach
- •8.1.2 Alternative Approaches to the Cavernous Sinus
- •8.1.3 Other Techniques
- •8.2 Embolic Agents
- •8.2.1 Polyvinyl Alcohol (PVA) and Embospheres
- •8.2.2 Stainless Steel Coils
- •8.2.5 Stents
- •8.3.1 Approaches (Benndorf et al. 2004)
- •8.3.2 Angiographic and Clinical Outcome
- •8.4 Discussion of Transvenous Occlusions
- •8.4.1 Approaches
- •8.4.1.1 IPS Approaches
- •8.4.1.6 Transfemoral Pterygoid Plexus Approach (PP Approach)
- •8.4.1.7 Transfemoral Cortical Vein Approach
- •8.4.1.10 Direct Puncture of the Foramen Ovale
- •8.4.2 Embolic Materials
- •8.4.2.1 Particles
- •8.4.2.2 Coils
- •HydroCoils (Hydrogel)
- •8.4.2.4 Ethylene-Vinyl Alcohol Copolymer (OnyxTM)
- •8.4.2.5 Stents and Covered Stents
- •8.4.3 Anatomic Results, Clinical Outcome and Complications of Transvenous Occlusions and Transarterial Embolizations
- •8.5 Conclusion
- •References
- •9. Alternative Treatment Options
- •9.1 Spontaneous Thrombosis
- •9.2 Manual Compression Therapy
- •9.4 Radiotherapy
- •9.5 Surgery
- •References
- •10. Hemodynamic Aspects of DCSFs
- •10.1 Introduction
- •10.2 Basic Hemodynamic Principles
- •10.3 Invasive Assessment of Hemodynamics
- •10.4 Flow Velocity and Pressure Measurements in Brain AVMs and DAVFs
- •10.5 Hemodynamics and Pathophysiology in CSFs
- •Comments
- •References
- •11. Summary
- •Subject Index
9.5 Surgery 289
overpacking. The latter can be a problematic matter and appears even in experienced surgical hands not to be completely under control. To prevent overpacking is no less important than avoiding underpacking that will result in persistence of the fistula. These concerns appear to be an inherent problem of direct surgical treatment for DCSFs.
Krisht et al. (1999) described a pretemporal approach to the anterior cavernous sinus for treatment of an “intractable” CS fistula that could not be treated by transvenous approach because of “thrombosis or absence of the petrosal sinuses”. The authors used an extended pterional approach, dissecting the dura in the pretemporal region and drilling the posterior orbital roof to gain access to the anterior extension of the cavernous sinus, where they were able to introduce an atraumatic intravenous cannula. Intraoperative angiography demonstrated complete fistula obliteration after introduction of thrombogenic coils.
The same group (Guerrero et al. 2006) recently reported another case of an “intractable” Type D fistula using a pretemporal direct approach combined with assisted coiling. The patient was reported to have undergone seven unsuccessful attempts at transarterial and transvenous embolization. The authors’ approach represents an elegant surgical technique to overcome the complex anatomy in this region as well as block the fistula flow provided by the ECA branches. In this particular case, however, details of the fistula’s angioarchitecture and why attempts at transvenous catheterizations remained unsuccessful are not reported. The only preoperative image shows an early arterial phase instead of a drainage pattern as erroneously mentioned in the text. All other figures show a stepwise increase of the coil packing. The final arteriogram does not allow one to determine whether complete or subtotal occlusion was achieved with any certainty. No fol- low-up arteriogram was provided. Thus, it remains somewhat questionable whether such “direct open embolization” was indeed indicated, and whether the performed coil packing was sufficient to achieve complete obliteration. Although it is advantageous to be able to target different CS compartments with coils, dense packing may be less easy to achieve while the CS is in fact open and its walls cannot be used as a buttress for the coils.
It can be stated that today so-called “technical challenges” in the EVT of Type D fistulas are mostly manageable with modern transvenous catheterization techniques and sophisticated bi-planar imag-
ing. State-of-the-art endovascular techniques must not be neglected when considering a direct surgical approach in a DCSF. Reported postoperative deficits, particularly with combined operative and technical efforts (general anesthesia, craniotomy, opening of the CS, etc.), have contributed to the current trend of endovascular management (van Loveren et al. 1991) and recently invalidated the need for direct surgical treatment of DCSFs.
In summary, direct surgery, if at all necessary, should be applied in selected cases only to facilitate endovascular approaches. Cooperation between operating and endovascular colleagues is essential for achieving optimal clinical and anatomical results. Current endovascular tools and high-resolution imaging capabilities have minimized the need for direct surgery in the therapeutic management of DCSFs.
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