Ординатура / Офтальмология / Английские материалы / Veterinary Ocular Pathology A Comparative Review_Dubielzig, Ketring, McLellan_2010

A B

C D

Figure 5.37  Uveitis diagnosed as

Cryptococcosis and Toxoplasmosis in a cat leading to post-traumatic sarcoma.

(A) Siamese, 7 years old: left eye represents the bilateral anterior uveitis. Chorioretinitis was also present. Based on serology, Cryptococcus and Toxoplasmosis was diagnosed as the etiology. (B) Same cat as in (A) 2 months after treatment: mild diffuse cortical opacities are developing. (C) Same cat as in (A,B) 2 weeks later: the cortical opacities are increasing in density.

(D) Same cat as in (A–C) 3 years later: the lens appears hypermature. Posterior synechia is present with vessels extending from the iris onto the lens. Iris bombe

is present and is especially obvious temporal. Histopathology demonstrated an early lens induced sarcoma. (E) Low magnification photomicrograph of the same eye, with Alcian blue PAS stain, showing hypermature cataract broad synechia and thick cellular and fibrous tissue around the wrinkled lens capsule (arrows). (F) Photomicrograph showing neoplastic spindle cells from the same eye internal to the tapetum (*).

Relative importance of non-surgical trauma

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Corneal effects of trauma

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Uveal effects of trauma

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Lens effects of trauma

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Retinal effects of trauma

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Scleral trauma

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Penetrating injuries

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Proptosis

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Feline post-traumatic sarcoma

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concurrent loss of cell cycle regulation in feline post-traumatic ocular sarcomas. J. Comp. Pathol. 133, 235–245.

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Diseases of the orbit

Diseases of the orbit may originate within the structures of the bony orbit (that vary between species), or in the orbital soft tissues, including the globe, extraocular muscles, and variable secretory tissues such as the zygomatic salivary gland, as well as the rich neurovascular supply to these tissues. However, many diseases affecting the orbit represent the extension of inflammatory or neoplastic processes from adjacent tissues. Thus, important anatomic considerations in the diagnosis of orbital disease also include the proximity of the oral and nasal cavities, the para-nasal sinuses, muscles of mastication, and brain.

INFLAMMATORY DISEASE OF THE ORBIT

Orbital inflammatory disease is relatively common

•In the COPLOW collection, orbital inflammation is usually diagnosed in conjunction with panophthalmitis, in globes that were enucleated because of intraocular inflammation that had concurrent orbital inflammation

•This combination is most common in dogs and there are 84 cases in the COPLOW collection.

Orbital cellulitis or abscess secondary to tooth root inflammation (Fig. 6.1)

•Most common in dogs, rabbits, chinchillas, and horses

■Periodontitis extending to the root apex

■Pulpitis due to exposure of the root canal from trauma or caries, which occurs less frequently in domestic animal species than in humans