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Ординатура / Офтальмология / Английские материалы / The Eye Book A Complete Guide to Eye Disorders and Health_Cassel, Billig, Randall_2001

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520 / APPENDIX

 

 

Type

Generic Name

 

 

 

 

 

 

Lodoximide

 

 

 

Olopatadine hydrochloride

Pheniramine maleate with naphazoline

Corneal edema

Sodium chloride

Combination drugs

(A mixture of more than one medication; for side effects, see the individual components of these drugs and additional notes

here.) Gentamicin and prednisolone Neomycin and dexamethasone

A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 521

 

Brand Name

Potential Side Effects

 

 

Alomide

Ocular: Burning and stinging on

 

 

 

insertion.

 

 

Systemic: (Very rare) nausea, dizziness,

 

 

and sedation.

 

Patanol

Ocular: Burning and stinging on inser-

 

 

tion, dry eye, foreign-body sensation,

 

 

conjunctival redness, puffy eyes.

 

 

Systemic: Headaches, coldlike

 

 

symptoms, taste change.

 

Naphcon-A

Same as antazoline phosphate with

 

Opcon-A

naphazoline.

 

 

 

 

 

 

Adsorbonac Ocular: Burning and stinging on Muro-128 insertion. Adsorbonac contains the

preservative thimerosal, which can cause an allergic reaction.

Pred-G

Neodecadron,

Neodexair

522 / APPENDIX

 

 

Type

Generic Name

 

 

 

 

 

 

Neomycin,

 

 

 

 

polymyxin B, and

 

 

dexamethasone

 

 

Neomycin,

 

 

polymyxin B, and

 

 

hydrocortisone

 

 

Neomycin,

 

 

polymyxin B, and

 

 

prednisolone

 

 

Oxytetracycline and

 

 

hydrocortisone

 

 

Polymyxin B and

 

 

bacitracin

 

 

Polymyxin B,

 

 

neomycin, and

 

 

bacitracin

 

 

Polymyxin B,

 

 

neomycin, and

 

 

gramicidin

 

 

Polymyxin B and

 

 

oxytetracycline

 

 

Tobramycin and

 

 

dexamethasone

 

 

Trimethoprim and

 

 

polymyxin B

 

A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 523

 

Brand Name

Potential Side Effects

 

 

 

 

Maxitrol,

Dexacidin,

Dexasporin

Cortisporin Hydrocortisone is a topical steroid with side effects similar to prednisolone.

Poly-Pred

Terra-Cortil

 

Polysporin

 

Triple

 

Antibiotic,

 

Neonatal,

 

Neosporin

 

Ocutricin,

Gramicidin in combination with poly-

Neosporin,

myxin B and neomycin is rarely

Neocidin

irritating.

Terramycin

Oxytetracycline in combination with

 

polymyxin B rarely causes allergic or

 

inflammatory eye reactions.

TobraDex

 

 

Trimethoprim can cause local eye

Polytrim

irritation including redness, burning,

 

stinging, and itching.

524 / APPENDIX

Type

Generic Name

 

 

 

 

 

Drugs used to dilate the pupils

Atropine sulphate

Cyclopentolate hydrochloride

Homatropine hydrobromide Hydroxyamphetamine

Phenylephrine HCl

Scopolamine hydrobromide

A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 525

Brand Name Potential Side Effects

 

Ocular: Irritation, allergic dermatitis,

 

pupil dilation, increased intraocular

 

pressure, and closed-angle glaucoma in

 

those susceptible.

 

Systemic: Central nervous system

 

effects, including convulsions, cognitive

 

impairment, and delirium. Dry mouth

 

due to a decrease in saliva production

 

is an early sign of an adverse reaction.

Cyclogyl

Same as scopolamine hydrobromide

 

(below). Additional central nervous sys-

 

tem side effects include hallucinations,

 

speech and motor impairment, dis-

 

orientation, restlessness, and emotional

 

disturbances.

 

Same as atropine sulphate.

Paremyd

Ocular: Irritation on insertion.

 

Systemic: Hypertension.

Mydfrin

Ocular: Pupil dilation, irritation on

NeoSynephrine

insertion, corneal swelling, and

 

rebound conjunctival reaction.

 

Systemic: Hypertension, change in

 

heart rate, and headaches.

 

Same as atropine sulphate, but the risk

 

of central nervous system side effects is

 

greater.

526 / APPENDIX

 

 

Type

Generic Name

 

 

 

 

 

 

Tropicamide

 

 

 

Dyes

Fluorescein sodium

Rose bengal

 

 

 

 

 

 

Glaucoma medications

 

 

 

 

 

 

 

 

Beta-blockers

Betaxolol

 

 

 

Carteolol

 

 

 

Levobunolol

 

 

 

Metipranolol

 

 

 

Timolol hemihydrate

 

 

 

Timolol maleate

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 527

 

Brand Name

Potential Side Effects

 

 

Mydriacyl

Ocular: Irritation, allergic dermatitis, in-

 

 

 

creased intraocular pressure, and closed-

 

 

angle glaucoma in those susceptible.

 

 

 

 

 

 

 

 

 

Ocular: Topical use can cause mild stinging and redness.

Systemic: Injected fluorescein can cause nausea, vomiting, and respiratory edema, and can lead to myocardial infarction.

Ocular: Pain and irritation on insertion is usually significant, so a topical anesthetic is usually used before insertion of rose bengal.

 

 

 

 

 

 

 

Betoptic

Same as timolol maleate (below), but

 

 

 

 

 

with less severe pulmonary side effects.

 

 

Ocupress

Same as timolol maleate (below).

 

 

Betagan

Same as timolol maleate (below).

 

 

OptiPranolol

Same as timolol maleate (below), but

 

 

 

with less severe systemic side effects.

 

 

Betimol

Same as timolol maleate (below).

 

 

Timoptic

Ocular: Redness and irritation and

 

 

 

reduced tear production.

 

 

 

Systemic: Changes in heart rate,

 

 

 

asthma, loss of libido, dizziness,

 

 

 

depression, and skin sensitivity.

 

 

 

 

 

 

 

 

 

 

528 / APPENDIX

Type

Generic Name

 

 

 

 

 

Miotics

Carbachol

Demecarium bromide

Echothiophate iodide

Isoflurophate

Physostigmine

Pilocarpine

Alpha-adrenergic agonists

Apraclonidine

A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 529

Brand Name Potential Side Effects

Isopto

Same as pilocarpine (below), but side

Carbachol

effects can be more severe.

Humorsol

Same as echothiophate iodide (below);

 

in addition, may cause cysts to form in

 

the iris.

Phospholine

Same as pilocarpine (below), but side

Iodide

effects can be more severe. More likely

 

to cause a cataract than other similar

 

drugs.

Floropryl

Same as demarcarium bromide.

Eserine sulfate

Same as demarcarium bromide; in

 

addition, allergic reactions are likely.

Isopto Carpine

Ocular: Stinging, burning, blurred vision,

Pilagan

induced nearsightedness, pupil constric-

Pilocar

tion, poor night vision, tearing,

 

cataracts, and retinal detachment.

 

Systemic: Headaches (browaches),

 

hypotension, change in heart rate,

 

difficulty breathing, pulmonary edema,

 

nausea salivation, sweating, cramps,

 

and diarrhea.

 

 

 

 

Iopidine

Ocular: Same as epinephrine (below)

 

 

 

and including abnormal upper eyelid

 

 

movement.

 

 

Systemic: Heart symptoms, as with

 

 

epinephrine, but less likely; dry mouth,

 

 

dry nose, fatigue.