Ординатура / Офтальмология / Английские материалы / The Eye Book A Complete Guide to Eye Disorders and Health_Cassel, Billig, Randall_2001
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520 / APPENDIX |
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Type |
Generic Name |
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Lodoximide |
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Olopatadine hydrochloride
Pheniramine maleate with naphazoline
Corneal edema
Sodium chloride
Combination drugs
(A mixture of more than one medication; for side effects, see the individual components of these drugs and additional notes
here.) Gentamicin and prednisolone Neomycin and dexamethasone
A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 521
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Brand Name |
Potential Side Effects |
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Alomide |
Ocular: Burning and stinging on |
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insertion. |
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Systemic: (Very rare) nausea, dizziness, |
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and sedation. |
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Patanol |
Ocular: Burning and stinging on inser- |
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tion, dry eye, foreign-body sensation, |
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conjunctival redness, puffy eyes. |
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Systemic: Headaches, coldlike |
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symptoms, taste change. |
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Naphcon-A |
Same as antazoline phosphate with |
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Opcon-A |
naphazoline. |
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Adsorbonac Ocular: Burning and stinging on Muro-128 insertion. Adsorbonac contains the
preservative thimerosal, which can cause an allergic reaction.
Pred-G
Neodecadron,
Neodexair
522 / APPENDIX |
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Type |
Generic Name |
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Neomycin, |
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polymyxin B, and |
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dexamethasone |
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Neomycin, |
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polymyxin B, and |
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hydrocortisone |
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Neomycin, |
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polymyxin B, and |
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prednisolone |
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Oxytetracycline and |
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hydrocortisone |
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Polymyxin B and |
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bacitracin |
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Polymyxin B, |
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neomycin, and |
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bacitracin |
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Polymyxin B, |
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neomycin, and |
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gramicidin |
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Polymyxin B and |
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oxytetracycline |
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Tobramycin and |
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dexamethasone |
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Trimethoprim and |
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polymyxin B |
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A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 523
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Brand Name |
Potential Side Effects |
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Maxitrol,
Dexacidin,
Dexasporin
Cortisporin Hydrocortisone is a topical steroid with side effects similar to prednisolone.
Poly-Pred
Terra-Cortil |
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Polysporin |
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Triple |
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Antibiotic, |
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Neonatal, |
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Neosporin |
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Ocutricin, |
Gramicidin in combination with poly- |
Neosporin, |
myxin B and neomycin is rarely |
Neocidin |
irritating. |
Terramycin |
Oxytetracycline in combination with |
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polymyxin B rarely causes allergic or |
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inflammatory eye reactions. |
TobraDex |
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Trimethoprim can cause local eye |
Polytrim |
irritation including redness, burning, |
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stinging, and itching. |
524 / APPENDIX
Type |
Generic Name |
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Drugs used to dilate the pupils
Atropine sulphate
Cyclopentolate hydrochloride
Homatropine hydrobromide Hydroxyamphetamine
Phenylephrine HCl
Scopolamine hydrobromide
A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 525
Brand Name Potential Side Effects
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Ocular: Irritation, allergic dermatitis, |
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pupil dilation, increased intraocular |
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pressure, and closed-angle glaucoma in |
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those susceptible. |
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Systemic: Central nervous system |
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effects, including convulsions, cognitive |
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impairment, and delirium. Dry mouth |
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due to a decrease in saliva production |
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is an early sign of an adverse reaction. |
Cyclogyl |
Same as scopolamine hydrobromide |
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(below). Additional central nervous sys- |
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tem side effects include hallucinations, |
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speech and motor impairment, dis- |
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orientation, restlessness, and emotional |
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disturbances. |
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Same as atropine sulphate. |
Paremyd |
Ocular: Irritation on insertion. |
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Systemic: Hypertension. |
Mydfrin |
Ocular: Pupil dilation, irritation on |
NeoSynephrine |
insertion, corneal swelling, and |
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rebound conjunctival reaction. |
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Systemic: Hypertension, change in |
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heart rate, and headaches. |
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Same as atropine sulphate, but the risk |
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of central nervous system side effects is |
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greater. |
526 / APPENDIX |
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Type |
Generic Name |
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Tropicamide |
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Dyes
Fluorescein sodium
Rose bengal
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Glaucoma medications |
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Beta-blockers |
Betaxolol |
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Carteolol |
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Levobunolol |
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Metipranolol |
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Timolol hemihydrate |
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Timolol maleate |
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A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 527
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Brand Name |
Potential Side Effects |
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Mydriacyl |
Ocular: Irritation, allergic dermatitis, in- |
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creased intraocular pressure, and closed- |
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angle glaucoma in those susceptible. |
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Ocular: Topical use can cause mild stinging and redness.
Systemic: Injected fluorescein can cause nausea, vomiting, and respiratory edema, and can lead to myocardial infarction.
Ocular: Pain and irritation on insertion is usually significant, so a topical anesthetic is usually used before insertion of rose bengal.
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Betoptic |
Same as timolol maleate (below), but |
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with less severe pulmonary side effects. |
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Ocupress |
Same as timolol maleate (below). |
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Betagan |
Same as timolol maleate (below). |
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OptiPranolol |
Same as timolol maleate (below), but |
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with less severe systemic side effects. |
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Betimol |
Same as timolol maleate (below). |
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Timoptic |
Ocular: Redness and irritation and |
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reduced tear production. |
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Systemic: Changes in heart rate, |
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asthma, loss of libido, dizziness, |
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depression, and skin sensitivity. |
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528 / APPENDIX
Type |
Generic Name |
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Miotics
Carbachol
Demecarium bromide
Echothiophate iodide
Isoflurophate
Physostigmine
Pilocarpine
Alpha-adrenergic agonists
Apraclonidine
A GUIDE TO MEDICATIONS AND SIDE EFFECTS / 529
Brand Name Potential Side Effects
Isopto |
Same as pilocarpine (below), but side |
Carbachol |
effects can be more severe. |
Humorsol |
Same as echothiophate iodide (below); |
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in addition, may cause cysts to form in |
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the iris. |
Phospholine |
Same as pilocarpine (below), but side |
Iodide |
effects can be more severe. More likely |
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to cause a cataract than other similar |
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drugs. |
Floropryl |
Same as demarcarium bromide. |
Eserine sulfate |
Same as demarcarium bromide; in |
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addition, allergic reactions are likely. |
Isopto Carpine |
Ocular: Stinging, burning, blurred vision, |
Pilagan |
induced nearsightedness, pupil constric- |
Pilocar |
tion, poor night vision, tearing, |
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cataracts, and retinal detachment. |
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Systemic: Headaches (browaches), |
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hypotension, change in heart rate, |
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difficulty breathing, pulmonary edema, |
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nausea salivation, sweating, cramps, |
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and diarrhea. |
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Iopidine |
Ocular: Same as epinephrine (below) |
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and including abnormal upper eyelid |
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movement. |
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Systemic: Heart symptoms, as with |
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epinephrine, but less likely; dry mouth, |
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dry nose, fatigue. |
