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Ростовский Государственный Медицинский Университет

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The Glaucomas Volume 1 Pediatric Glaucomas_Sampaolesi, Zarate_2009

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<<< < Предыдущая 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 4849 / 4949

476 Chapter 27 False-Positive Diagnoses

Fig. 27.12 Clinical history No. 4, RE and

LE: Optic disc (HRT)

Fig. 27.13 HRT of the same patient. Visual field of the clinical history No. 4, normal in both eyes

Conclusion

This is a false positive glaucoma. The real diagnosis is congenital bilateral megalopapilla without glaucoma.

		Chapter

	Epilog	28
	Epilog

The study of primary congenital glaucoma has shown that a congenital anomaly of the pretrabecular chamber angle leads to ocular hypertension. If its surgical treatment does not normalize the intraocular pressure it leads to glaucomatous optic neuropathy, identical to that found in adults, but with a much faster development and identical defects in the visual field. In the literature on congenital glaucomas, neither the risk factors nor the normal-tension glaucomas are described.

This simple summary should indicate that in the future, when 24-h IOP monitoring in open-angle

glaucomas would be possible, the concept of glaucoma may change. Ocular pressure will not be seen as a risk factor, but rather the cause of glaucomatous optic neuropathy.

Currently, 24-h IOP monitoring is not possible, because it is very inconvenient for the doctor to take the pressure at 6 a.m. in the morning or because hospitals do not pay for DPC. In the near future, we will have a new automatic device that will enable such monitoring.

Subject Index

A
Abderhalden-Fanconi syndrome									423
acrocentric chromosome								56
adenovirus				81
adrenalectomy					300
Ahmed valve				112, 116, 171, 172
Aicardi’s syndrome						231, 238
albinism		238
Alcian blue				457
alkaptonuria				424, 425, 428
allele 57
alphagan		470
amblyopia			23, 126, 275, 389
amniotic cavity					63
anaesthetic agent
– effects on intraocular pressure									19
aniridia		59, 103, 112, 114, 388–390, 393, 398
anisometropia					126
anophthalmia					440
ANOVA, see one-way analysis of variance
anterior
–	chamber			48
–	embryotoxon				23, 367, 398
–	iris insertion				4
aplasia		391, 441
apparent high insertion of the iris									108, 109, 313, 314
applanation tonometry							20, 23
arachnodactyly					424, 431
Argon laser				92
athalamia			116, 380
atrophy		203, 332
–	of the iris			314
– of the iris pigment layer								354
–	of the pigment epithelial layer of the iris 333
– of the retinal nerve fiber								202
atropine		141, 155
atypical coloboma						391
Axenfeld’s syndrome							103, 144, 368
axial length				48, 50
B
back illumination						15
barbiturate				19
Barkan
–	lens	127

–	membrane			62, 100, 101, 131, 146, 149, 152, 443,
	460
Barraquer model					183
basal encephalocele						214, 227, 229
Beaver
–	handle		137
–	knife	134
Bebie cumulative defect curve 290, 362, 375
Bell phenomenon					36
Berger space				425
Betcherev disease					425
bilateral
–	leukocoria			448
–	peripheral uveitis					302
biomicroscopy				42, 82, 86, 88, 112, 214
bipolar microdiathermy							180
black triangle				103, 107
blastocyst			63, 65
blastomere			63
blebitis		176
blepharitis			303
blepharoconjunctivitis							381
blepharospasm				11, 299
blepharostat opening						36
Bowman membrane						384, 386
brachymorphia 431, 433
brimonidine tartrate						472
broad basal root					214
Brusini glaucoma staging system									330, 348
Budenz maneuver					110
bulbar enlargement						15
bullous
–	keratitis		384
–	keratopathy			382
buphthalmia				438
buphthalmos				1, 13, 14, 51, 369
Busacca
–	iris crest line				101
–	iris process			78
–	trabecular conjunctival layer								62, 77
C
café-au-lait-colored spots								401
campimetry			472
capsular pseudoexfoliation								348

480 Subject Index

capsulohyaloid angle 338 Cardona gonioscopic lens 128 cataract 23, 423

central nervous system (CNS) 227


–	defects		227
central scotoma				236
centromere			56
chamber angle
–	anatomic variations					91
–	anatomy		71
–	blockage		352
–	clinical classification					90
–	congenital anomaly					343
–	embryology			61
–	examination			81
	–	biomicroscope			82
	–	slit lamp		82
–	gonioscopic visibility					90
–	in newborns			99
–	in pigmentary glaucoma						338
–	intrauterine development						62
–	pigmentary ring				337
–	premature children					99
–	scleral angle			75
–	shape 91

–type I 131, 211

–type II 144

Charge’s syndrome					231
choroidal angioma					404
chromosome				55
–	abnormality			56
ciliary
–	body band (CBB)				77, 78, 91, 99
	–	cysts	348
–	muscle		67, 72
	–	tendon		61
circumpapillary aplasia 389
cleft
–	lip	214
–	palate		214

Coats disease 56, 449 coherent light tomography 110 coloboma 214, 227, 229, 371

–	atypical	391
–	of the iris	326
–	of the limbus 378

colobomatous lens 115

confocal tomography 193, 296, 297

congenital
–	cataract surgery	451
–	colobomatous syndrome		227
–	dysversion 347
–	glaucoma (see also there)		1
	– after surgery	50

–

chronology of symptoms

–

classification

–

clinical features

–

clinical history

119

–

diagnosis

–

echometry

41, 51

–

epidemiology 2

–

etiopathogenesis

3, 393, 455

–

genetics

–

heredity

2, 9, 344

–

history

–

indication for surgery

109

–

infantile

–

molecular genetics

–

nonhereditary

–

optic nerve

205

–

pathological chamber angle

104, 107

–

prevalence

–

refractory, see there

–

results of surgery

187

–

surgery

125

–

surgical indications

–

type I 243, 248, 253, 255, 261

–

valve devices

171

–

visual field

289

–

mesodermal dystrophy

431

conjunctival flap

180

conjunctivitis

303, 306

conventional perimetry

297

cornea/corneal

48, 67, 72

–

alterations

112

–

diameter

11, 42

–

edema

11, 43, 111, 113, 126, 275

–

echogram

–

flap

455

–

measurement of diameter

–

mesodermal dysgenesis

398

–

posterior polymorphous dystrophy 13

–

Rieger mesodermal dysgenesis

367

corneascleral

–

trabecular meshwork

61, 95, 156

–

wall

86, 89

corneomesodermal iris

101

corpus callosum agenesia

238

corticoid

299

–

side effects

301

cortisone

300, 475

–

glaucoma

300, 302

cri-du-chat syndrome

cryptophthalmia

440

crystalline

–

lens

88, 389, 394

–

placode

Cushing’s syndrome

300

Subject Index

481

cyclodialysis			131, 139, 140, 371
cyclodiathermy 316
cystinosis		423
D
dacryocystitis			303, 306
De Toni syndrome 423
De Vincentiis
–	knife	125
–	technique		127

deep nonpenetrating sclerotomy 292, 318, 321

Degrouchy syndrome	56
deoxyribonucleic acid	55
Descemet membrane	12, 75, 76, 140, 376, 386
– tears 12, 20
dexmethasone 300

differential light sensitivity (DLS) perimetry 294

diffuse
–	limbus	367
–	mesodermal remnants						462
–	sclerocorneal limbus					15
–	uveal neurofibromatosis						402
direct ophthalmoscopy						214
disc
–	cupping	15
–	dysversion			347
–	notches	210
disciform central leukoma							382
DNA sequence				58
dolichocephaly				431
dolichostenomelia					424, 431
Down syndrome					56, 393
Draeger’s hand applanation tonometer 29, 33
dyscoria 112
–	of the pupil			115
dysplasia		214
dystrophy		401
E
echography		41, 43
–	before/after surgery					52
echometry		13, 25, 41, 42, 51
–	equipment			42
–	follow-up		53
–	plastic cylinder				44
–	statistical methods					45
ectoderm		63, 64
Edward syndrome					56
Elliot operation				316, 371
Elschnig ring				200, 202, 211
embryopathy				437
embryotoxon				15, 23, 317, 367, 369, 378, 379, 398
emmetropia			313, 343
emmetropization					306

encephalophthalmic dysplasia								440
encephalotrigeminal neuroangiomatosis									404
endoderm			63, 64
endogenous ochronosis							424, 425
endophthalmitis					176
endothelium			12
–	tears	12
epiphora		11, 299, 303
episcleral angioma						404
esotropia		374
ether 19
examination of the newborn								19
exfoliation syndrome 94, 215, 331, 348
exophthalmos				401
exotropia		406
eye enlargement					17
eyelid, dilation of veins							15
F
facial
–	angioma		404
–	asymmetry			375
Fankhauser and Roussel lens								93, 94, 341
ferric chloride test						425
fetal
–	mesoderm			4
–	pars planitis				447
fetopathy		437, 440
fiber
–	atrophy		202
–	layer defect				225
fibrillocellular trabeculae							67
Fishberg test			425
flat cornea			397
fluorescein paper strips							20
fluorometholone					301
fluothane		19
flurbiprofen			301
frequency doubling technology (FDT)									296
Friedenwald artery						146
frontal skin angioma						373
funduscopy			20
G
gastroenteritis					421
gel densitometry					58
gene
–	abnormality				57
–	alteration		58
–	classification				57
–	information				57

–map 58

–message 58 genetic counseling 59

482 Subject Index

genitourinary disorder							59
glaucoma
–	for pseudoexfoliation (PEX)								348
–	history		1
–	juvenile		2
–	staging		194
glaucomatous
–	neuropathy			214
–	optic disc progression							195
glutaraldehyde				132
Goldmann
–	applanation tonometry							23, 29
–	lens	81, 84, 92
–	perimetry			250, 289
–	three-mirror lens					23
Gomori’s reticulum						457
goniodysgenesis					2, 59, 95, 96, 205, 215, 282, 311,
	331, 358, 398
–	with megalopapilla						214
goniolens			86
goniophotography						23, 92, 94
goniopuncture				131, 170, 292
–	with YAG laser				318, 321
gonioscope			81, 88
gonioscopy/gonioscopic								15, 20, 23, 92, 99, 128, 140
–	contact lens			81, 92, 104
–	postsurgical			140
–	visibility		91
goniosynechia				140, 243, 369
goniotomy			1, 3, 125, 131, 275, 458
–	complications				126
–	surgical indications						126
–	technique			130
H
Haab striae			12, 20, 112, 113, 245, 261, 299
halothane			19, 20, 29
hand applanation tonometer 37
Hannover space					338
Harms
–	microscope			134
–	probe	134, 135
–	technique			136
Heidelberg Retina Tomograph (HRT) 193, 205, 294
hemangioblastoma						405
hemangioma				405
hemangiomatosis					412
hemianopsia				238
hemihypertrophy					405
hemiplegia			434
hemitrabeculotomy						353
high-pass-resolution perimetry									294
HIV 81
home tonometry					37

homocystinuria						424
Hurler syndrome						424
hyaluronic acis 300
hyaluronidase					300
hydrophthalmos						13, 369
hyperaminoaciduria							421
hypercanthus					373
hypermetropia					313, 343
hyperopia				72, 389
hypertelorism					214, 373
hypertrophy					401
hyphema				116, 131, 137, 451
hypophysis nonfunctional tumor 215
hypoplasia				328, 369
–	optic nerve				228
hypothalamia					116
I
infantile congenital glaucoma										2
internal sclerotomy							1, 125
intracranial calcification									405
intraocular pressure (IOP)									1, 42, 49, 126, 187, 333
–	at different ages						31
–	effects of anaesthetic agents									19
–	in children				29
	–	normality criteria						29
–	measurement in a newborn									35
–	regression line					33
–	statistical test					31
intraocular tumor							449
intrascleral angioma							404
intubation				19
invagination of the lens								66
IOP, see intraocular pressure
iridectomy				145, 146, 155, 178, 183, 371
irideremia				388
irido-cyclo-trabeculectomy 456, 457
iridodialysis					451
iridodonesis					434
iridopexy				451
iridopupillary membrane									61
iris		72, 99
–	anterior insertion						460
–	anterior synechia						384
–	apparent high insertion								463
–	atrophy			340
–	Busacca baseline layer								78
–	channel			78
–	coloboma				326, 378, 389
–	depression				324
–	development					67
–	halo		356
–	heterochromia					401
–	holes		389

Subject Index

483

–	hyperplasia				374
–	hypoplasia			368, 379
–	mesodermal dysgenesis							386, 398
–	parenchyma				12
–	peripheral atrophy						115
–	positive peripheral transillumination										116
–	process		95, 461
–	retroillumination						333
–	Rieger mesodermal dysgenesis									367
–	root	78, 91
–	stroma		61
–	synechia			381
–	transillumination						332
–	vascular pillars					103
–	wall	86
Ivanoff ’s muscle					61, 101
J
Janken syndrome						405
juvenile glaucoma						2, 131, 205, 282
juxtacanalicular tissue							78, 155
K
keratoconus				275
keratoplasty				112, 114
keratotorus				379
Klippel-Trenaunay syndrome									412
Kozlov’s nonpenetrating deep sclerotomy											146
Krukenberg’s spindle							331, 332, 335, 348, 354
krypton laser				92
kyphoscoliosis					431
L
laser trabeculoplasty							406
late congenital glaucoma								2, 282, 292, 311
–	in adults			316
–	in young people					316
–	with lower nasal malformation									323
Lawford syndrome						406
lens placing				81
lenticular capsule						67
leukocoria			437, 440, 449
leukoma			12, 13, 112, 114, 382, 383, 386
Leydhecker gonioscopic lens									128
lid speculum				33
lipoma		398
Littman formula						193
lower nasal malformation								323, 326
Löwe’s oculocerebrorenal syndrome										421, 424
lysosome			300
M
Mackay-Marg tonometer								33
Mackensen trabeculotome probe 134

macula aplasia						389
Marchesani syndrome								431, 433
Marfan syndrome							424, 428, 431
Masson’s trichrome							457
megalocornea					49, 299
megalodisc				214
megalopapilla					214, 228, 233, 467, 476
–	classification					215
– parameters of the HRT									217
–	without glaucoma							223
melanosis oculi						416
Mendelian feature							58
meningeal angioma							404, 405
mental retardation							59
Mermoud forceps							157, 166
mesoderm/mesodermal									64
–	dysgenesis			378, 379
–	iris	101
–	remnant			99, 100, 460, 464
	– in the fetus					102
–	triangle		101
metacentric chromosome									56
metaplasia of the mesodermal tissue 311
methoxyflurane						19, 29
methylcellulose						81
microcornea				447
micropapilla				228
microphakia				431, 433
microphthalmia						438
microspherophakia							434
microsurgery				92
Millong’s phosphate							459
minimum square method									44
Minsky maneuver							137, 163, 165, 180, 311, 458
MIRA		158
molecular biology							55
Momers and Katsch test									425
monosomy				56
Moria trabeculotome								136
morning glory syndrome									214, 227–230
mucocele			51
mydriasis			448
myopia		13, 72, 299, 313, 332, 343, 389, 447
myopic
–	astigmatism					238
–	eye	51
N
narrow angle glaucoma								97
nasal ectasia of the fundus									238
nasolacrimal duct obstruction 299
nephroblastoma						397
neural crest cells						5
neurofibromatosis							401, 416

484 Subject Index

neuroma		401
nevus
–	flammeus		404
–	of Ito	416
–	of Ota	416
–	sebaceous syndrome						231
noncontact echometry							25
nonconventional contrast perimetry 296, 297
nonpenetrating deep sclerotomy (NPDS) 92, 155,
	406, 456, 458
–	chamber angle					169
–	gonioscopy			167
normal
–	chamber angle					99
–	mesodermal tissue, see also pectinate ligament 61
–	optic disc		195
	– parameters of the HRT 217
–	pressure glaucoma						475
Norrie disease				438, 441, 442
NPDS, see nonpenetrating deep sclerotomy
nystagmus			389
O
obstetric trauma					299
ochronotic pigment						428
Octopus perimetry						215, 250, 290
Octosmart			290
ocular
–	damage		2
–	hypertension				2, 318, 368, 394
–	malformation				367
–	melanocytosis				416
–	pressure		299
–	rigidity of newborn						35

oculodigital phenomenon 381 oligodendroglia 401

one-way analysis of variance (ANOVA) 205

ophthalmoscopy				20, 193
optic
–	disc
	–	coloboma		228, 231, 232
	–	congenital dysversion					347
	–	cup/disc area ratio				207
	–	cupping 306
	–	normal parameters				195
	–	pits	214, 236, 237
	–	pseudonormal			197
	–	stereochronoscopy				193
–	nerve		15, 16, 292, 347, 467
	–	congenital anomaly				227
	–	dysplasia		238
	–	examination			193
	–	hypoplasia		228
	–	in congenital glaucoma					205
–	neuropathy			215

–	vesicle	66
Ossoinig shell			25, 44
oximeter		21
P
pallor 214
palpebral angioma					404
Pascal’s tonometry					23, 29
Patau syndrome				56
Patau-Bartholin syndrome								440
pathological
–	chamber angle				107
–	mesodermal remnants							4, 462
Paufique technique					136
PCR, see polymerase chain reaction
pear-shaped lens					115
Pearson’s correlation coefficient									294
pectinate ligament					4, 61, 460
penthrane		19, 29, 41, 53, 448
perimetry lesion				297
peripapillary staphyloma								228, 232
peripheral
–	athalamia		386
–	atrophy of the iris					342
–	iridodonesis			433, 434
Perkins tonometer					29
Peters anomaly/syndrome								112, 115, 380, 381, 384,
	387, 397, 398
Petit perilenticular space								338
Pfaundler-Hurler disease								424
phakoma		401
phakomatosis			401
photophobia			11, 17, 49, 275, 299, 303
phthisis bulbi			51, 52
Pierre-Robin syndrome							452
pigment dispersion					332, 348, 363
pigmentary glaucoma						116, 315, 331
–	differential diagnosis						348
–	genetics	344
–	height of the apparant insertion of the iris										341
–	medical therapy				352
–	natural history				348
–	surgery	352
pigmentary syndrome						332
–	in the anterior segment and chamber angle										333
pigmentation on the surface of the lens										336
pilocarpine		350, 358, 376
POAG, see primary open-angle glaucoma
polymerase chain reaction (PCR)									58
posterior embryotoxon							317, 369, 378, 379
postsurgical gonioscopy							140
posttrabeculotomy gonioscopy									140, 142
primary open-angle glaucoma (POAG)										58
proencephalon				64

progressive oculoacoustic cerebral degeneration 441

Subject Index

485

prostaglandin				292
pseudocongenital cortisone glaucoma 303
pseudoexfoliation						349
pseudoglaucomatous disc								214, 226
pseudoglioma				437, 446
pseudopapilla				240, 241
pseudophakia				175
pupillary
–	dilatation			352
–	membrane			67
pure congenital glaucoma								50, 462
Q
quadrantanopsia					238
R
Recas classification						303
Reese dysplasia					438, 440
refraction			343
refractory congenital glaucoma									187, 265, 270, 275,
	291, 463
–	surgery		144
–	trabeculectomy					144
–	trabeculotomy				144
regular astigmatism							13
reticulin fiber				461, 464
reticulogenesis				464
retina/retinal				67
–	detachment			350
– nerve fiber layer (RNFL)								194
retina-optic nerve system								72
retinitis pigmentosa							380
retinoblastoma					57, 133, 404, 437, 449
retinofluoresceinography 193, 236
retinopathy of prematurity (ROP) 446, 449, 450
retinoschisis				236
retroillumination					336
–	of the iris			333
retrolental fibroplasia							438, 446, 448, 449
rhizomelic spondylitis							425
Rieger mesodermal dysgenesis									173, 371, 374, 377,
	386
Rieger’s syndrome						59, 144, 369, 370, 374, 397
Rohen iridoscleral membrane									62, 77
ROP, see retinopathy of prematurity
Roussel and Fankhauser lens									93, 94, 341
rubella		437
rubeola		299
Rubinstein-Taybi syndrome								452
S
Sauer retractor					35
Scheimpflug principle							457
Schiötz’ s tonometer							35
Schirmer syndrome							405

Schlemm canal					61, 67, 72, 75, 76, 87, 95, 131, 132,
	137
Schwalbe line					4, 15, 74–76, 86, 87, 101, 140
sclera/scleral					72
–	channel			76
–	flap	135, 137, 146, 180, 455
	– suture			184
–	septum		75
–	spur	76
–	trabecular meshwork							76, 77
sclerocornea				387, 397
scleromalacia					172
sclerotomy				1
scotoma			236
scotomatous defect							210
sevoflurane				19, 20
sevorane			19, 20, 110, 111
sinusotomy				155
slit lamp			82
– optical coherence tomography (SL-OCT)										110
slow photomotor reflex								354
spherophakia					431
spider finger				431
spots		401
spring conjunctivitis							299
staphyloma				381, 383
stereochronoscopy							249, 253
stereophotogrammetry								193
stereoscopic photograph								193
strabismus				23, 126, 275, 447
–	caliper		11, 25
Streiff posterior corneal marginal dysplasia										367
student t test					44
Sturge-Weber-Krabbe syndrome									404–406, 416
subconjunctival lipoma								398
submetacentric chromosome 56
superficial mesenchymal iris layer									368
surface optical microscopy technique 150
Sussman lens					446
Swan gonioscopic lens								127
T
tearing		11
telecanthus				372
Tenon capsule					158, 176, 180
three-mirror lens						81, 98
thrombus
–	in a collector					358
– of pigments and cells								357
tilted disc syndrome							238, 239
tomato iris				451
tonometry				53
– calibration curve in newborns									36
toxoplasmosis					302
trabeculae			76

486 Subject Index

trabecular
–	Descemet membrane							157, 167, 170
–	fiber	77
–	meshwork			72, 75–77
trabeculectomy						1, 3, 108, 127, 458
–	surgical technique						180
trabeculotomy					1, 49, 108, 125, 127, 243, 275
–	after surgery					143
–	Harms technique						135
–	Lyon School technique							136
–	mechanism of action							141
–	reasons		132
transient amaurosis							229
transillumination						15, 137, 163, 433, 434
–	of the iris			332
translational research							55
trapezoidal
–	anterior chamber						354
–	scleral flap			147
triangular
–	flap	163
–	goniosynechia					375
trisomy		56
–	-13	440
trophoblast				63
tropicamide				15
Tukey test			205
tunica vasculosa lentis 67, 438
Turner syndrome						56, 316

ultrasound biomicroscopy (UBM) 116, 162, 167 uvea/uveal

–	area	77
–	melanoma 416
uveitis		299, 303, 348

V
valve device			171
–	complications			176
–	postsurgical biomicroscopy 175
Vannas scissors				135
vascular
–	pillar	99
–	pseudopapilla			240
viscocanalostomy 155
visual field			289, 348
–	defect	199, 200, 358
–	examination			294
vitelline sac			63
vitreous length				48

von Hippel-Lindau’s retinocerebellar hemangioblastomatosis 416

von Recklingshausen neurofibromatosis 401

Walker-Warburg‘s syndrome 231 welding 368

Wieger capsulohyaloid ligament 338, 350, 425

Wilms tumor		59,	397
Worst
–	lens 127
–	technique	130

X-chromosome-linked syndrome 441

YAG goniopuncture 170

Zarate’s method 464

<<< < Предыдущая 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 4849 / 4949

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