- •Preface
- •Contributors
- •1. Patient selection and pre-operative assessment
- •2. Corneal topography and its role in refractive surgery
- •3. Corneal anatomy, physiology and response to wounding
- •4. Surgical procedures
- •6. Case reports
- •7. Co-management issues
- •8. Surface laser treatments: an alternative to LASIK?
- •9. Wavefront technology
- •10. Future trends in refractive surgery
- •Index
Index
Aberrometry, 15–16 |
Complications of surgery, 39–40 |
microanatomy of, 17–18 |
see also Wavefront aberrations, |
clear lens extraction, 32 |
non-native cells of, 18–19 |
Wavefront technology |
corneal infections, 40 |
refractive index, 17 |
Accommodation, surgical restoration of, 77–8 |
dry eye, 39–40 |
remodelling, 50 |
Accuracy, 63 |
intraocular pressure elevation, 40 |
resident cells of, 18 |
LASIK, 59 |
LASEK, 29 |
stem cell theory, 19 |
unilateral versus bilateral treatment, 62 |
visual complications, 41 |
ultrastructure, 18–19 |
Adhesion, 23 |
LASIK, 30, 37–9, 59 |
wound healing, 22–3 |
AK see Arcuate keratotomy |
corneal integrity, 38–9 |
adhesion, 23 |
American Society of Cataract and |
diffuse lamellar keratitis, 38 |
cell migration, 22 |
Refractive Surgery, 56 |
epithelial ingrowth, 37–8 |
cell proliferation, 22 |
Ametropia, 5, 12 |
interface debris, 38 |
latent phase, 22 |
intraocular lenses, 78 |
keratectasia, 39 |
Corneal hypoaesthesia, 21 |
Anisometropia |
microstriae, 38 |
Corneal infection, 40 |
post-PRK, 36 |
retinal detachment, 39 |
Corneal inlay lenses, 27, 78 |
with unilateral treatment, 62 |
visual complications, 41 |
Corneal innervation, 21 |
Arcuate keratotomy, 27, 33 |
overcorrection, 39 |
Corneal integrity post-LASIK, 38–9 |
Argon fluoride excimer laser, 76–7 |
presbyopic surgery, 33 |
Corneal oedema, 22 |
Astigmatism, 12 |
PRK |
Corneal pachymetry, 4–5, 59 |
post-surgical, 14 |
anisometropia, 36 |
Corneal profile, post-operative |
Autorefractors, 41 |
epithelium irregularity, 36 |
measurement, 41–2 |
|
haze, 36 |
Corneal regeneration and healing, 20–1 |
Bailey–Lovie chart, 3, 41 |
visual complications, 41 |
Corneal sensitivity, 21–2 |
Bausch and Lomb keratometer, 11 |
regression, 39 |
Corneal shape, 10–11 |
BCVA see Best-corrected visual acuity |
stromal infiltrates, 40 |
descriptors of, 10 |
Best-corrected visual acuity, 3 |
undercorrection, 39 |
Corneal stroma, 19 |
LASIK, 59 |
visual, 40–1 |
microanatomy, 19 |
phakic intraocular lenses, 31 |
binocular vision, 43 |
ultrastructure, 19 |
Binocular vision problems, 43 |
contact lens fitting, 43 |
Corneal surface regularity index, 10 |
Bioptics, 78 |
haloes, 43 |
Corneal topography, 4, 9–16 |
Bowman’s layer, 17, 19 |
management of, 41 |
and aberrometry, 15–16 |
innervation, 21 |
non-tolerance of monovision, 43–4 |
classification, 9–10 |
microstriae post-LASIK, 38 |
poor-quality night vision, 42–3 |
corneal shape, 10–11 |
ultrastructure, 19 |
poor-quality vision, 42 |
history, 9 |
British Society for Refractive Surgery, 54, 56 |
starburst effects, 43 |
limitations of, 15 |
|
Confocal microscopy, 23–4 |
measurement methods, 11–14 |
Calcitonin gene-related protein, 21 |
Contact lenses |
cornea as projector system, 13–14 |
Cancer risk of refractive surgery, 44 |
corneal warpage, 15 |
cornea as reflector system, 11–12 |
Case reports, 49–52 |
factors influencing decision to cease use, 2 |
presentation of data, 12–13 |
Cataracts, risk of, 44 |
fitting post-surgery, 43 |
videophotokeratoscopy, 12 |
Cell migration, 22 |
intraocular, 78 |
in refractive surgery, 14–15 |
Cell proliferation, 22 |
polymegathism, 20 |
Corneal transparency, 22 |
CIL see Corneal inlay lenses |
Contour maps, 68 |
Corneal uniformity index, 10 |
Clear lens extraction, 27, 32 |
Contract sensitivity function, 6 |
Corneal warpage, 15 |
complications, 32 |
Contrast Acuity Assessment test, 42 |
Corneal wound healing, 20–1, 22–3 |
results, 32 |
Contrast sensitivity post-LASIK, 59–60 |
endothelium, 20–1, 23 |
surgical procedure, 32 |
Corneal anatomy, 17–22 |
epithelium, 22–3 |
Co-management, 53–6 |
Corneal endothelium, 20–1 |
adhesion, 23 |
general schedules for, 55–6 |
long-term damage, 44 |
cell migration, 22 |
GP’s role, 54–5 |
microanatomy, 20 |
cell proliferation, 22–3 |
insurance and legal issues, 56 |
replication and regeneration, 20–1 |
latent phase, 22 |
ophthalmologist’s role, 55 |
ultrastructure, 20 |
stroma, 23 |
optometrist’s role, 53–4, 55 |
wound healing, 20–1, 23 |
Cost issues, 61 |
professional relationships/ |
Corneal epithelium, 17–19 |
|
responsibilities, 54 |
basement membrane, 18 |
Descemet’s layer, 20 |
training, 54 |
ingrowth post-LASIK, 37–8 |
Diffuse interstitial keratitis, 59 |
|
irregularity post-PRK, 36 |
Diffuse lamellar keratitis, 38, 50–1 |
|
|
Index ■ 81 |
Diode thermokeratoplasty, 31 |
Keratitis, 23, 40 |
post-operative care, 29 |
Directorate for Optometric Continued |
Keratoconus, 2, 4, 27 |
post-operative follow-up, 39 |
Education and Training, 54 |
diagnosis of, 12 |
refractive outcome, 39 |
Dry eye, 39–40 |
Keratocytes, 19, 23 |
surgical procedure, 29 |
Drysdale effect, 12 |
loss of, 24 |
versus LASIK and PRK, 28, 30–1, 60–1 |
|
morphology, 24 |
visual complications, 41 |
Elevation, 11 |
Keratoglobus, 2 |
visual outcome, 40 |
Emmetropia, 67, 78 |
Keratometry, 11 |
Lasers |
European Society of Cataract and |
data presentation, 12–13 |
argon fluoride, 76–7 |
Refractive Surgeons, 56 |
Keratomileusis see Laser in-situ |
broad beam, 58, 65 |
Excimer lasers, 28, 57–8 |
keratomileusis |
excimer, 28, 57–8 |
argon fluoride, 76–7 |
Keratophakia, 78 |
holmium, 31 |
cost of, 61 |
Keratoscopy, 11 |
krypton fluoride, 28, 57–8 |
equipment, 58 |
KR-7000P, 12 |
picosecond, 77 |
krypton fluoride, 28, 57–8 |
Krypton fluoride excimer laser, 28, 57–8 |
solid state, 77 |
new developments, 76–7 |
|
LASIK see Laser in-situ keratomileusis |
see also LASEK; LASIK |
Lamina densa, 18 |
Lipofuscin, 24 |
Eye Laser Association, 76 |
Lamina lucida, 18 |
Long-term implications of surgery, 44 |
EyeSys, 4, 12 |
Langerhans’ cells, 18–19 |
|
|
LASEK see Laser subepithelial keratectomy |
Microkeratomes, 58–9 |
Flap infection, 50–1 |
Laser in-situ keratomileusis, 3, 27, 29–30 |
cost of, 61 |
Flap melt, 51 |
clinical outcome, 30 |
Microstriae post-LASIK, 38 |
Flap transaction, 49–50 |
complications, 30, 37–9, 59 |
Microvilli, 18 |
Fleischer’s rings, 4 |
corneal integrity, 38–9 |
Mintel report, 53 |
Fuchs’ endothelial dystrophy, 2 |
diffuse lamellar keratitis, 38 |
Modulation transfer function, 72, 74 |
Fundus examination, 5 |
epithelial ingrowth, 37–8 |
Monovision, non-tolerance of, 43–4 |
|
interface debris, 38 |
Muscle balance, 5–6 |
General Medical Council, 54 |
keratectasia, 39 |
Myopia, LASIK for, 30, 60 |
General Optical Council, 54 |
microstriae, 38 |
|
General practitioners, role in co- |
retinal detachment, 39 |
National Health Service, 62–3 |
management, 54–5 |
confocal microscopy, 23–4 |
Neovascularization, 4 |
Glaucoma, 2 |
contraindications, 29 |
Nidek OPD, 15 |
Glycosaminoglycans, 19 |
corneal hypoaesthesia, 21 |
Night vision, poor-quality, 42–3 |
|
damage to microvilli in, 18 |
|
Haloes, 43 |
development of, 57 |
Oculus Keratograph, 4 |
Hartmann–Shack, 71 |
for hyperopia, 30 |
Oculus Pentacam, 14 |
Haze post-PRK, 36 |
indications, 29 |
Ophthalmologists, role in co-management, 55 |
Hemidesmosomes, 18, 22 |
keratocyte morphology, 24 |
Opticians Act (1989), 55 |
Holliday diagnostic summary, 11 |
with LASEK in other eye, 51 |
Optometrists |
Holmium laser thermokeratoplasty, 31 |
late flap lift, 52 |
co-management fees, 53–4 |
Hypermetropia, 67 |
for myopia, 30 |
indemnity insurance, 56 |
Hyperopia, LASIK for, 30, 60 |
nerve fibre regeneration after, 22 |
role in co-management, 55 |
|
post-operative care, 30 |
Orbscan, 4, 13, 14, 42, 49, 78 |
Iatrogenic ectasia, 39 |
post-operative follow-up, 36–9 |
Overcorrection, 39 |
ICRS see Intracorneal ring segment |
results, 59–60 |
|
Indemnity insurance, 56 |
accuracy, 59 |
Pachymetry see Corneal pachymetry |
Infiltrates, 19 |
contrast sensitivity, 59–60 |
Patient selection, 1–8 |
post-surgery, 40 |
high myopia, 60 |
decision to cease contact lens use, 2 |
International Council of Refractive |
hyperopia, 60 |
occupational groups, 1 |
Surgery, 56 |
loss of best-corrected vision, 59 |
Pelli–Robson chart, 5, 42 |
Intracorneal ring segments, 27, 31 |
predictability, 59 |
Penetrating keratoplasty, 14 |
advantages and disadvantages, 31 |
stability, 59 |
Pentacam, 78, 79 |
surgical procedure, 31 |
surgical procedure, 29–30, 58–9 |
Phakic intraocular lenses, 27, 31–2 |
Intraocular lenses, 77 |
versus LASEK and PRK, 28, 30–1, 58 |
advantages and disadvantages, 32 |
contact lenses, 78 |
visual complications, 41 |
anterior chamber lens implantation, |
see also Phakic intraocular lenses |
visual outcome, 40 |
31–2 |
Intraocular pressure, 2, 5 |
Laser subepithelial keratectomy, 27, 28–9, |
in conjunction with laser surgery, 78 |
elevation post-surgery, 40, 60 |
60–1 |
posterior chamber lens implant, 31–2 |
IOLMaster, 78 |
clinical outcome, 30 |
Photoablation, 27 |
|
complications, 29 |
Photorefractive keratectomy, 2, 27 |
Javal–Schiötz keratometer, 11 |
contraindications, 29 |
complications |
|
increased prescription after, 50 |
anisometropia, 36 |
Keeler Tearscope, 6 |
indications, 29 |
epithelium irregularity, 36 |
Keratectasia, 39, 51–2 |
with LASIK in other eye, 51 |
haze, 36 |
82 ■ Refractive surgery: a guide to assessment and management
confocal microscopy, 23–4 corneal aesthesia, 21 keratocyte morphology, 24
nerve fibre regeneration after, 22 post-operative follow-up, 36 refractive outcome, 36
removal of corneal epithelium in, 18 unilateral versus bilateral treatment, 62 versus LASEK and LASIK, 28
visual complications, 41 visual outcome, 40
Phototherapeutic keratectomy, 2 cornea after, 15
Placido
Antonio Placido, 9 cone systems, 12 disc systems, 4, 9, 12
Polymegathism, 20 Polymorphonuclear leukocytes, 19, 22 Poor-quality vision, 42
Post-mitotic cells, 22 Post-operative follow-up, 35–48
initial post-operative period, 35–40 complications, 39–40
LASEK, 39 LASIK, 36–9 PRK, 36
time scale for, 35 Pre-operative assessment, 1–8
contract sensitivity function, 6 corneal pachymetry, 4–5 corneal topography, 4
full refraction, 3 fundus examination, 5 intraocular pressure, 5 muscle balance, 5–6 pupil diameter, 3–4
slit-lamp examination, 4 tear secretion, 6
visual acuity, 3
Predicted corneal acuity, 10 Presbyopia, 3
Presbyopic surgery, 27, 32–3 complications of, 33 corneal, 32
intraocular, 32–3 outcome, 33 scleral, 32
PRK see Photorefractive keratectomy Professional responsibilities, 54 Projection techniques, 13–14 Proteoglycans, 19, 23
PTK see Phototherapeutic keratectomy Pupil diameter, 3–4
Purkinje image, 11, 14
Quad maps, 13
Radial keratotomy, 27, 44–5, 65 ocular integrity, 44–5 refractive stability, 44
visual performance, 45 Reflection techniques, 11–12 Refraction, 3
post-operative measurement, 41 Refractive correction, 70 Regression, 39
Retinal detachment post-LASIK, 39 RK see Radial keratotomy
Rods, 24
Royal College of Ophthalmologists, 56
SimK see Simulated keratometry readings Simulated keratometry readings, 10–11 Slit-lamp examination, 4
post-operative, 42 Snellen chart, 3 Spot diagrams, 72
Staphylococcus aureus, 51 Starburst effects, 43 Stromal wound healing, 23 Super vision, 73–4
Surgical procedures, 14–15, 27–34 decision-making, 27–8
excimer laser technology, 28 history, 27
treatment plan, 28
see also LASEK; LASIK; PRK
TACs see Transient amplifying cells Tear secretion, 6
Topographic Modelling System, 12 Training, 54
Transient amplifying cells, 19, 22 Treatment plan, 28
Undercorrection, 39
Unilateral versus bilateral treatment, 61–2 accuracy, 62
PRK, 62 safety, 62
subjective issues, 62
United Kingdom and Ireland Society of Cataract and Refractive Surgery, 56
United Kingdom, refractive surgery in, 76 United States, refractive surgery in, 77
Videokeratoscopy, 11
see also under Corneal topography Videophotokeratoscopy, 12
Visual acuity, 3
post-operative measurement, 41 Visual complications, 40–1
binocular vision, 43 contact lens fitting, 43 haloes, 43
LASEK, 41
LASIK, 41 management of, 41
non-tolerance of monovision, 43–4 poor-quality night vision, 42–3 poor-quality vision, 42
PRK, 41
starburst effects, 43 Visual outcome, 40–1 complications, 40–1
unaided vision, 40 Visual quality, 42 Vogt’s striae, 4
von Hippel–Lindau syndrome, 51
Wavefront aberration, 66–8 analysis of, 68–70 measurement of, 71
and refractive correction, 70 super vision, 73–4
use in refractive surgery, 72–3 Wavefront technology, 65–75
Wound healing see Corneal wound healing
Zernike polynomials, 68, 69
Zonula occludentes, 18
