- •Preface
- •Contents
- •Acknowledgments
- •Abbreviations
- •Introduction
- •1: Diagnosis of Keratoconus
- •1.1 Clinical Findings
- •1.1.1 External Signs
- •1.1.2 Retinoscopy Signs
- •1.1.3 Slit Lamp Biomicroscopy Signs
- •1.2 Corneal Hysteresis
- •1.2.1 Principles
- •1.3 Confocal Microscopy
- •1.4 Specular Microscopy
- •1.5 Corneal Topography
- •1.5.1 Instruments Measuring Corneal Surface
- •1.5.1.1 Curvature-Based Instruments
- •1.5.1.2 Elevation Based Topographers
- •Bibliography
- •2.1 Morphological Patterns
- •2.2 Topographical Patterns
- •2.2.3.1 The Normal Cornea
- •2.2.4 Summary of Topographic Criteria of Keratoconus
- •2.4 Forme Fruste Keratoconus
- •2.5.1 Clinical Findings
- •2.5.2 Topographical Findings
- •2.5.3 Complications
- •2.5.4 Differential Diagnosis
- •Bibliography
- •3: Management of Keratoconus
- •3.1 Introduction
- •3.2 Management Modalities
- •3.2.1 Noninterventional Managements
- •3.2.1.1 Spectacle Correction
- •3.2.1.2 Contact Lenses
- •3.2.2 Interventional Procedures
- •3.2.2.1 Conductive Keratoplasty (CK)
- •3.2.2.2 Penetrating Keratoplasty
- •3.2.2.3 Lamellar Keratoplasty (DALK)
- •3.2.2.4 Intracorneal Rings (ICRs)
- •Mechanism of Actions
- •Conditions to Use ICRs
- •Guidelines
- •Factors for Poor Visual Outcome
- •Contraindications
- •Relative Contraindications
- •Considerations
- •Complications
- •Practical Notes in Using the Rings
- •3.2.2.5 Corneal Collagen Cross-Linking
- •Introduction
- •Indications
- •Conditions
- •Contraindications
- •Expected Changes After CxL
- •Typical Final Clinical Outcomes
- •Complications
- •3.2.2.6 Intraocular Refractive Lenses
- •Indications
- •Conditions
- •Contraindications
- •Considerations
- •Ophthalmic Examination
- •Basic Concepts
- •Complications
- •3.2.3 Combination Between Treatment Modalities
- •3.3 Management Parameters
- •3.3.1 Introduction
- •3.3.2 Management Parameters
- •3.3.2.3 Environment
- •3.3.2.4 Progression
- •3.3.2.5 Corneal Thickness
- •3.3.2.7 Refractive Errors and the Visual Acuity
- •3.3.2.8 Corneal Transparency and Stress Lines
- •Bibliography
- •4: Case Study
- •Introduction
- •Step 1: Analyzing Step
- •Step 2: Management Suggestion Step
- •Step 3: Discussion Step
- •4.1 Case 1
- •4.1.1 Step 1: Analyzing Step
- •4.1.2 Step 2: Management Suggestions
- •4.1.3 Step 3: Discussion
- •4.2 Case 2
- •4.2.1 Step 1: Analyzing Step
- •4.2.2 Step 2: Management Suggestions
- •4.2.3 Step 3: Discussion Step
- •4.3 Case 3
- •4.3.1 Step 1: Analyzing Step
- •4.3.2 Step 2: Management Suggestions
- •4.3.3 Step 3: Discussion Step
- •4.4 Case 4
- •4.4.1 Step 1: Analyzing Step
- •4.4.2 Step 2: Management Suggestions
- •4.4.3 Step 3: Discussion Step
- •4.5 Case 5
- •4.5.1 Step 1: Analyzing Step
- •4.5.2 Step 2: Management Suggestions
- •4.5.3 Step 3: Discussion Step
- •4.6 Case 6
- •4.6.1 Step 1: Analyzing Step
- •4.6.2 Step 2: Management Suggestions
- •4.6.3 Step 3: Discussion Step
- •4.7 Case 7
- •4.7.1 Step 1: Analyzing Step
- •4.7.2 Step 2: Management Suggestions
- •4.7.3 Step 3: Discussion Step
- •4.8 Case 8
- •4.8.1 Step 1: Analyzing Step
- •4.8.2 Step 2: Management Suggestions
- •4.8.3 Step 3: Discussion Step
- •4.9 Case 9
- •4.9.1 Step 1: Analyzing Step
- •4.9.2 Step 2: Management Suggestion
- •4.9.3 Step3: Discussion
- •Index
Classifications and Patterns |
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of Keratoconus and Keratectasia |
ClassiÞcation of KC is the Þrst step in approaching the disease because the severity of the disease and the stage at which the patient is diagnosed and treated affect treatment results. KC can be classiÞed according to the morphology of the cone and the pattern of corneal topography.
2.1Morphological Patterns
Morphologically, KC has three types of cones:
(a)Nipple cones, characterized by their small size (5 mm) and steep curvature. The apical center is often either central or paracentral and commonly displaced inferonasally (Fig. 2.1).
(b)Oval cones, which are larger (5Ð6 mm), ellipsoid, and commonly displaced inferotemporally (Fig. 2.2).
(c)Globus cones, which are the largest (>6 mm) and
may involve over 75% of the cornea. Figures 2.3 and 2.4 are the tangential curvature map and the thickness map respectively of a globus cone, note the generalized corneal thinning.
Morphology of the cone is determined according to its size on corneal topography. The best map to evaluate the cone is the tangential map since it is the best to highlight corneal irregularities. In mild cases, cone morphology may be indeterminate.
2.2Topographical Patterns
2.2.1Classification According to Elevation Map
Cone location is determined only by the elevation maps. The elevation maps can be displayed either by best Þt sphere mode (BFS) as shown in Fig. 2.5, or by best Þt toric ellipsoid mode (BFTE) as shown in Fig. 2.6. The best to locate the cone is the BFS, and the best to evaluate the real height of the cone is the BFTE. On the BFS, the cone can be central, paracentral, or peripheral as shown in Figs. 2.7 and 2.8. This classiÞcation is important for differentiating KC from PMD and for treatment as will be discussed later in details.
2.2.2Classification According to Thickness Map
There are two patterns of the thickness map in KC, the conic or dome-like and the ÒbellÓ shape. The conic or dome-like shape (Fig. 2.9) is encountered in KC, while the bell shape is encountered in PMD (Fig. 2.10). The bell shape comes from the inferior wide thinning of the cornea found with PMD. When the bell shape is seen, PMD is to be suspected and inserting intracorneal rings carries the risk of perforation, this will be discussed later in details.
2.2.3Classification According to Curvature Map
Topographically, KC can be classiÞed according to elevation maps, to thickness map or to curvature maps.
Upon studying corneal topography, special attention should be paid to the anterior sagittal curvature map. There are several abnormal signs on these maps that we
M.M. Sinjab, Quick Guide to the Management of Keratoconus, |
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DOI 10.1007/978-3-642-21840-8_2, © Springer-Verlag Berlin Heidelberg 2012 |
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2 Classifications and Patterns of Keratoconus and Keratectasia |
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Fig. 2.1 Nipple cone. A small steep central or paracentral cone
Fig. 2.2 Oval cone. A steep elliptical cone that is commonly displaced inferotemporally
2.2 Topographical Patterns |
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Fig. 2.3 Globus cone. A large steep cone involving over 75% of the cornea
Fig. 2.4 Globus cone. Corneal thickness map: generalized corneal thinning
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2 Classifications and Patterns of Keratoconus and Keratectasia |
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OD
Sphere
Fig. 2.5 The elevation map displayed in the best Þt sphere ßoat mode
OD
Toric Ellipsoid
Fig. 2.6 The elevation map displayed in the best Þt toric ellipsoid ßoat mode
2.2 Topographical Patterns |
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Fig. 2.7 A central cone as shown on the elevation map with the best Þt sphere ßoat mode; the white arrows point at the cone
Fig. 2.8 A peripheral cone as shown on the elevation map with the best Þt sphere ßoat mode; the white arrow points at the cone
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2 Classifications and Patterns of Keratoconus and Keratectasia |
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Fig. 2.9 Dome shape of the cone in KC on the corneal thickness map
OD
Bell Shape
Fig. 2.10 Bell sign on the corneal thickness map in PMD
