- •Preface
- •Contents
- •Acknowledgments
- •Abbreviations
- •Introduction
- •1: Diagnosis of Keratoconus
- •1.1 Clinical Findings
- •1.1.1 External Signs
- •1.1.2 Retinoscopy Signs
- •1.1.3 Slit Lamp Biomicroscopy Signs
- •1.2 Corneal Hysteresis
- •1.2.1 Principles
- •1.3 Confocal Microscopy
- •1.4 Specular Microscopy
- •1.5 Corneal Topography
- •1.5.1 Instruments Measuring Corneal Surface
- •1.5.1.1 Curvature-Based Instruments
- •1.5.1.2 Elevation Based Topographers
- •Bibliography
- •2.1 Morphological Patterns
- •2.2 Topographical Patterns
- •2.2.3.1 The Normal Cornea
- •2.2.4 Summary of Topographic Criteria of Keratoconus
- •2.4 Forme Fruste Keratoconus
- •2.5.1 Clinical Findings
- •2.5.2 Topographical Findings
- •2.5.3 Complications
- •2.5.4 Differential Diagnosis
- •Bibliography
- •3: Management of Keratoconus
- •3.1 Introduction
- •3.2 Management Modalities
- •3.2.1 Noninterventional Managements
- •3.2.1.1 Spectacle Correction
- •3.2.1.2 Contact Lenses
- •3.2.2 Interventional Procedures
- •3.2.2.1 Conductive Keratoplasty (CK)
- •3.2.2.2 Penetrating Keratoplasty
- •3.2.2.3 Lamellar Keratoplasty (DALK)
- •3.2.2.4 Intracorneal Rings (ICRs)
- •Mechanism of Actions
- •Conditions to Use ICRs
- •Guidelines
- •Factors for Poor Visual Outcome
- •Contraindications
- •Relative Contraindications
- •Considerations
- •Complications
- •Practical Notes in Using the Rings
- •3.2.2.5 Corneal Collagen Cross-Linking
- •Introduction
- •Indications
- •Conditions
- •Contraindications
- •Expected Changes After CxL
- •Typical Final Clinical Outcomes
- •Complications
- •3.2.2.6 Intraocular Refractive Lenses
- •Indications
- •Conditions
- •Contraindications
- •Considerations
- •Ophthalmic Examination
- •Basic Concepts
- •Complications
- •3.2.3 Combination Between Treatment Modalities
- •3.3 Management Parameters
- •3.3.1 Introduction
- •3.3.2 Management Parameters
- •3.3.2.3 Environment
- •3.3.2.4 Progression
- •3.3.2.5 Corneal Thickness
- •3.3.2.7 Refractive Errors and the Visual Acuity
- •3.3.2.8 Corneal Transparency and Stress Lines
- •Bibliography
- •4: Case Study
- •Introduction
- •Step 1: Analyzing Step
- •Step 2: Management Suggestion Step
- •Step 3: Discussion Step
- •4.1 Case 1
- •4.1.1 Step 1: Analyzing Step
- •4.1.2 Step 2: Management Suggestions
- •4.1.3 Step 3: Discussion
- •4.2 Case 2
- •4.2.1 Step 1: Analyzing Step
- •4.2.2 Step 2: Management Suggestions
- •4.2.3 Step 3: Discussion Step
- •4.3 Case 3
- •4.3.1 Step 1: Analyzing Step
- •4.3.2 Step 2: Management Suggestions
- •4.3.3 Step 3: Discussion Step
- •4.4 Case 4
- •4.4.1 Step 1: Analyzing Step
- •4.4.2 Step 2: Management Suggestions
- •4.4.3 Step 3: Discussion Step
- •4.5 Case 5
- •4.5.1 Step 1: Analyzing Step
- •4.5.2 Step 2: Management Suggestions
- •4.5.3 Step 3: Discussion Step
- •4.6 Case 6
- •4.6.1 Step 1: Analyzing Step
- •4.6.2 Step 2: Management Suggestions
- •4.6.3 Step 3: Discussion Step
- •4.7 Case 7
- •4.7.1 Step 1: Analyzing Step
- •4.7.2 Step 2: Management Suggestions
- •4.7.3 Step 3: Discussion Step
- •4.8 Case 8
- •4.8.1 Step 1: Analyzing Step
- •4.8.2 Step 2: Management Suggestions
- •4.8.3 Step 3: Discussion Step
- •4.9 Case 9
- •4.9.1 Step 1: Analyzing Step
- •4.9.2 Step 2: Management Suggestion
- •4.9.3 Step3: Discussion
- •Index
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4 Case Study |
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4.7 |
Case 7 |
4.7.1 Step 1: Analyzing Step |
A 16-year-old male patient is complaining of progressive deterioration of vision, and recently, he has been diagnosed to have bilateral KC. He has not been treated yet and does not use spectacles.
His MR is (Table 4.7.1):
Table 4.7.1 Manifest refraction
Eye |
Sphere |
Cylinder |
Axis |
UCVA |
BSVCA |
OD |
0 |
−1.75 |
60 |
0.7 |
1.0 |
OS |
−0.5 |
−0.5 |
120 |
0.7 |
1.0 |
Slitlamp examination shows clear corneas with no stress lines. Other ocular examination is within normal limits.
Figure 4.7.1 is corneal topography of the right eye. Figure 4.7.2 is the anterior curvature map after color modification.
Figure 4.7.3 is corneal topography of the left eye. Figure 4.7.4 is the anterior curvature map after color modification.
1. The patient is very young; he is 16 years old. KC is supposed to be progressive in this age.
2. UCVA and BSCVA are very good and it seems to be a simple refractive error rather than KC.
3.Both corneas are clear with no stress lines.
4.Corneal topography.
(a)Right eye:
•Figure 4.7.1 is corneal topography of the right eye. Corneal thickness at the thinnest location is 489 m, the maximal K-reading is 48.7 dpt, and the Km is 45.7 dpt.
•Figure 4.7.2 is the anterior curvature map. It is either PMD or PLK, but when considering other maps, it is PLK. This case is pattern 5 according to the author’s classification.
•According to Krumeich, it can be considered as grade 2.
Fig. 4.7.1 Corneal topography of the right eye: mild PLK
4.7 Case 7 |
135 |
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Fig. 4.7.2 Anterior elevation map of the right eye. The curvature pattern is PLK. According to author’s classification, it is pattern 5
Fig. 4.7.3 Corneal topography of the left eye
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4 Case Study |
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Fig. 4.7.4 Anterior curvature map of the left eye. The curvature pattern is round hot spot IS. According to author’s classification, it is pattern 7
(b)Left eye:
•Figure 4.7.3 is corneal topography of the left eye. Corneal thickness at the thinnest location is 449 m, the maximal K-reading is 59.5 dpt, and the Km is 51.6 dpt.
•Figure 4.7.4 is the anterior curvature map. The cone is eccentric and according to the author’s classification, it is pattern 7.
•According to Krumeich, it can be considered as grade 2.
4.7.2Step 2: Management Suggestions
Table 4.7.2 summarizes patient data and the corresponding individual suggestion(s) for treatment, and presents with a final summary of the best management.
4.7.3Step 3: Discussion Step
The patient is 16-year-old and his case is progressive, yielding the need for CxL.
ICRs are not suitable for this case due to the following reasons:
Table 4.7.2 Management suggestions |
|
|
Factors |
Patient data |
Suggested treatment |
Progression |
Yes |
CxL |
CL tolerance |
? |
Can be tried after |
|
|
CxL |
Age |
16 |
|
Sex |
Male |
|
Transparency and |
Clear |
CxL and PRK |
stress lines |
|
or ICRs |
Refractive error (S.E) |
RE: −1.0 |
CxL and PRK |
|
LE: −0.75 LE |
|
BSCVA Vs UCVA |
very good |
CxL and PRK or ICRs |
K-max |
RE: 48.7 dpt |
CxL and PRK |
|
LE:59.5 dpt |
or ICRs |
Corneal thickness @ |
RE: 489 m |
RE: CxL and PRK |
atthinnest location |
LE: 449 m |
or ICRs |
|
|
LE: CxL for |
|
|
progression not for |
|
|
PRK |
Management |
CxL ± PRK |
|
summary: |
|
|
1.The manifest refractive error is very small especially astigmatism.
2.The topographical astigmatism is not reasonable enough to indicate implanting ICRs. It is noticed
4.7 Case 7 |
137 |
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that the left eye is more advanced than the right eye although the topographical astigmatism is smaller in the left eye. That is because the cone in the left eye is more eccentric than that in the right eye.
3.Implanting rings usually pushes the cone toward the center of the cornea leading – in such a case – to increase in both spherical and astigmatic components of the refractive error!
PRK and CxL may be suitable to regularize the cen-
tral 5 mm of the cornea and therefore improve the
quality of vision. This is possible because of the suitable thickness, but it is to remember that 40 m of maximal ablation depth is an important issue and the priority is for the irregular astigmatism.
What are suitable also are glasses after CxL. That is probably the most logic choice since the refractive error is so small and both UCVA and BSCVA are very good. The patient has not tried the spectacles yet, so it is appropriate to persuade him to have CxL and continue with glasses.
