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© 2007, Elsevier Limited. All rights reserved.

No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the Publishers. Permissions may be sought directly from Elsevier’s Health Sciences Rights Department, 1600 John F. Kennedy Boulevard, Suite 1800, Philadelphia, PA 19103-2899, USA: phone: ( 1) 215 239 3804; fax: ( 1) 215 239 3805; or, e-mail: healthpermissions@elsevier.com. You may also complete your request on-line via the Elsevier homepage (http://www.elsevier.com), by selecting ‘Support and contact’ and then

‘Copyright and Permission’.

First published 1984

Second edition 1989

Third edition 1996

Fourth edition 2002

Fifth edition 2007

ISBN 978-0-7506-8897-0

British Library Cataloguing in Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Cataloging in Publication Data

A catalog record for this book is available from the Library of Congress

Note

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the publisher nor the author assume any liability for any injury and/or damage.

The Publisher

The

Publisher’s policy is to use paper manufactured

from sustainable forests

For Elsevier:

Commissioning Editor: Robert Edwards

Development Editor: Rebecca Gleave

Project Manager: Gail Wright

Designer: Erik Bigland

Illustration Manager: Gillian Richards

Illustrator: Barking Dog Art

Preface

This fifth edition is intended as an update of the previous editions on the

 

practical and clinical aspects of binocular vision for students and

 

practitioners. The ‘how to do it’ approach has been retained and in some

 

cases extended by new tables, flow charts and case studies. The theory of

 

binocular vision has been kept to the minimum necessary to understand

 

the investigative and therapeutic procedures.

 

The first and second editions drew largely on Professor David Pickwell’s

 

enormous clinical and research experience. This new edition, which is the

 

third completed by me since Professor Pickwell’s retirement, continues to

 

contain a great deal of the late Professor Pickwell’s sound advice. Most of the

 

alterations have been revisions and updates in view of recent research, and

 

this new edition contains 864 references compared with 565 in the fourth

 

edition. The fact that contemporary research has not necessitated any major

 

changes in emphasis is a tribute to Professor Pickwell’s original work. There

 

has been a gradual evolution of binocular vision tests and treatments from

 

using artificial instruments that create unnatural viewing conditions

 

towards more natural methods that are less disruptive to normal binocular

 

vision. This evolution is desirable, and some of the older techniques that do

 

not add useful additional clinical information and are not in common use

 

have been omitted from this edition.

 

A great many theories and therapies have been suggested concerning

 

binocular vision anomalies and it can be difficult to sort the wheat from the

 

chaff. The healthcare disciplines are increasingly tending to cope with this

 

issue by adopting an evidence-based approach. In this approach, high-quality

 

scientific research is used to investigate old and new techniques alike.

 

Investigative approaches and treatments that have been validated in this

 

way are taken most seriously, and ones that have less rigorous support are

 

openly acknowledged as unproven. An attempt has been made in Pickwell’s

 

Binocular Vision Anomalies to rank different methods, especially treatments,

 

according to an evidence-based approach. Greatest weight is given to

 

approaches that have been validated with double-masked, randomized,

 

placebo-controlled trials.

 

The book is divided into four parts: the general investigation of bino-

 

cular anomalies, heterophoria, strabismus and incomitant deviations. In the

 

parts on heterophoria and strabismus the main features of these conditions

 

are summarized in a general introductory chapter and are then discussed

vii

in more detail in subsequent chapters.

PREFACE

A comprehensive glossary of orthoptic terminology is included at the end of the book. It is hoped that this will make the book more accessible to students at earlier stages in their training and to practitioners who have not benefited from recent training or reading in this field. The glossary also may be of use as revision notes for students. It includes abbreviations in an attempt to bring some degree of standardization to clinical practice.

This edition also includes appendices of information that should be particularly useful for clinicians. For common conditions, there are clinical worksheets and diagnostic algorithms to help the practitioner to adopt a logical approach to investigation, diagnosis and treatment. The appendices also include test norms, highlight confusing aspects, list suppliers of clinical equipment and a guide for various examinations. The final appendix is a guide to the CD-ROM that accompanies this book, which includes video clips of commonly encountered incomitant deviations, links to full-colour images and quizzes.

In this book the term ‘squint’ has been avoided and replaced by ‘strabismus’ or, synonymously, ‘heterotropia’. This is because of the confusing commonplace use of the term ‘squint’ to refer to half-shut eyes. The term ‘deviation’ is used as a generic term to describe both heterophoria and strabismus.

Sadly, Professor Pickwell died in 2005 while the present edition was in preparation. Professor Pickwell’s systematic and rigorously scientific approach played an important part in the evolution of optometry and orthoptics from subjects that were considered by many to be an art into a science. It is hoped that this book will be a lasting tribute to his major contribution to this field.

I wish to acknowledge the contributions of my colleagues at the Institute of Optometry, in clinical practice and research collaborators. Particular thanks to Jewlsy Mathews for her comments on Chapter 13 and to Dr Dorothy Thompson. Finally, my thanks to the staff of Elsevier for their support.

Bruce Evans

London 2006

viii

Preface to the first edition

This book is intended to provide a clinical text on the investigation and

 

management of binocular vision anomalies by methods other than

 

medicine and surgery. It is hoped that it will be useful to the student facing

 

the subject for the first time, and also to the established practitioner seeking

 

a reference to the binocular anomalies likely to be seen in everyday practice.

 

The aim has been to produce a ‘how to do it’ book. It is not a textbook on

 

the theory of binocular vision. There are a number of excellent books which

 

cover the anatomy, physiology and mechanisms of binocular vision. The

 

theory has therefore been kept to the minimum necessary for an adequate

 

appreciation of the anomalies, their investigation and treatment. I have

 

assumed that the reader has a basic knowledge of normal binocular vision

 

or is acquiring this simultaneously with clinical studies. I also assume a

 

knowledge of the general procedures of eye examination and refractive

 

methods.

 

The history and past literature of orthoptics seem to be full of descrip-

 

tions of unsubstantiated methods which have come and gone as it was

 

found that they did not work. At times it has appeared to have been a

 

maze of suggested procedures which have varied from ‘cure alls’ to useful

 

clinical ideas. I cannot claim to have explored all of them. What I have

 

tried to do is describe the methods which I have found effective, and

 

where possible provided the references for practical evaluations. I have

 

tried to write from my own particular experience which has extended over

 

30 years. In doing so, I am very aware of others whose experience has been

 

parallel, but not necessarily the same. As far as possible, I have also tried

 

to reflect some of their views, and acknowledge their contributions to the

 

ongoing development of clinical practice.

 

To help the student, I have tried to provide a recognizable pattern in

 

dealing with the conditions described, and I hope thereby to have pro-

 

duced a mnemonic approach to the subject which will aid learning and

 

application in a clinical setting. Each condition is dealt with in the general

 

order of definition, investigation, evaluation and management. Under the

 

heading of management, I have considered five non-medical possibilities:

 

removing any general cause, correcting refractive error, orthoptics,

 

relieving prisms and referral. These patterns will be obvious in the early

 

chapters, and are assumed in the later ones.

 

I wish particularly to acknowledge the work and encouragement given

ix

to me by my colleagues in the binocular vision clinics at the University of

PREFACE TO THE FIRST EDITION

Bradford, who have stimulated my thoughts and actions over many years. I would mention Mr M. Sheridan and Dr W. A. Douthwaite. I am particularly indebted in this respect to Dr T. C. A. Jenkins who also read the manuscript and made many helpful suggestions. I wish to thank Mrs J. Paley for interpreting the initial draft and for typing the manuscript, and also the staff of the Graphics Unit of the University of Bradford for their help with the illustrations.

David Pickwell 1984

x

1 NATURE OF BINOCULAR VISION ANOMALIES

Introduction

Binocular vision is the coordination and integration of what is received from the two eyes separately into a single binocular percept. Proper functioning of binocular vision without symptoms depends on a number of factors, which can be considered under three broad headings:

(1)The anatomy of the visual apparatus

(2)The motor system that coordinates movement of the eyes

(3)The sensory system through which the brain receives and integrates the two monocular signals.

Anomalies in any of these can cause difficulties in binocular vision, or even make it impossible. This is illustrated schematically in Figure 1.1. In considering the binocular difficulties of a particular patient, therefore, all three parts of the total system need to be investigated:

(1)Anatomy. Abnormalities in the anatomy of the visual system can be either developmental, occurring in the embryological development of

Two anatomically aligned eyes

Fusional reserves

Motor

 

 

 

 

Sensory

Fusion lock

 

 

 

fusion

 

 

 

 

fusion

 

 

 

 

 

 

 

 

One percept

 

Figure 1.1 Simplified schematic model illustrating the interaction of an ocular motor function (fusional reserves) with a sensory system (sensory fusion) to achieve binocular

2single vision.

NATURE OF BINOCULAR VISION ANOMALIES

1

the bony orbit, ocular muscles or nervous system; or acquired through accident or disease.

(2) Motor system. Even if the motor system is anatomically normal, anomalies can occur in the functioning that can disturb binocular vision or cause it to break down. These may be due to disease or they may be malfunctions of the physiology of the motor system. For example, excessive accommodation due to uncorrected hypermetropia can result in excessive convergence due to the accommodation–convergence relationship. This is a fairly frequent cause of binocular vision problems. Examples of disease affecting the motor system are haemorrhages involving the nerve supply to the extraocular muscles, local changes in intracranial pressure near the nerve nuclei, or pressure on the nerves or nerve centres from abnormal growths of intracranial tissue. Such conditions require urgent medical attention to the primary condition and early recognition is therefore essential. The investigation for this type of pathology is discussed in Chapter 17.

(3)Sensory system. Anomalies in the sensory system can be caused by such factors as a loss of clarity of the optical image in one or both eyes, an image larger in one eye than the other (aniseikonia), anomalies of the visual pathway or cortex, or central factors in the integrating mechanism. Difficulties in the coordinating mechanism of the motor system can also be accompanied by adaptations and anomalies in the sensory system, such as suppression, abnormal retinal correspondence or amblyopia. These may occur in order to lessen the symptoms caused by the motor anomaly but are adaptations of the sensory system.

The anatomical, motor and sensory systems must be adequate for normal

 

binocular vision to be present. The position of the eyes relative to each

 

other is determined first by their anatomical position. Humans have

 

forward-looking eyes placed in the front of the skull, and this brings the

 

visual axes of the two eyes almost parallel to each other. In most cases,

 

they are slightly divergent when the position is determined only by

 

anatomical factors, and this is known as the position of anatomical rest.

 

In normal circumstances, this state seldom exists, as physiological factors

 

are nearly always operative also. When a person is conscious, muscle

 

tone and postural reflexes usually make the visual axes less divergent: the

 

position of physiological rest. Another physiological factor affecting the posi-

 

tion of the eyes is the accommodation–convergence relationship: the eyes

 

will converge as accommodation is exerted, and this is known as accom-

 

modative convergence. The final adjustment of the eyes is made to achieve

 

single binocular vision. This is known as fusional (disparity) vergence and

 

positions the retinal images on corresponding points (or within corre-

 

sponding Panum’s areas). For distance vision, this will produce parallel

 

visual axes.

 

If fusional vergence is suspended, for example by covering one eye, the

 

eyes will adopt a dissociated position. This is slightly deviated from the active

3

position that is maintained when all of the factors are free to operate. This

1PICKWELL’S BINOCULAR VISION ANOMALIES

slight deviation from the active position when the eyes are dissociated

is known as heterophoria, sometimes abbreviated to phoria. It is present in most people. The situation where a heterophoria is not present and the dissociated position is the same as the active position is known as orthophoria. It is stressed that the term ‘heterophoria’ applies only to the deviation of the eyes that occurs when the fusional factor is prevented by covering one eye or dissociated by other methods such as distorting one eye’s image so that it cannot be fused with the other, e.g. the Maddox rod method (p 68). Heterophoria is sometimes described as a latent deviation: it only becomes manifest on dissociation of the two eyes. Sometimes the eyes can be deviated even when no dissociation is introduced. This more permanent deviation is called heterotropia or strabismus. Other, less favoured terms include squint (a confusing term because it is often used by patients to refer to half-closed eyes) or cast. Ocular deviations can, therefore, be classified as either heterophoria or strabismus, but there are other important practical classifications that need to be considered in investigating the binocular vision of a patient.

The symptoms and clinical features of most binocular vision anomalies fit into recognizable patterns. The recognition of these patterns is the process of diagnosis and this is an obvious preliminary to treatment. The classifications adopted here are intended to assist diagnosis (Fig. 1.2). The term deviation is used generically to describe strabismus and heterophoria. Cyclotorsional and vertical deviations often occur together, when they may be described as cyclovertical deviations.

Prevalence of binocular vision anomalies

Strabismus and amblyopia affect 2–4% (Adler 2001) and 3% of the population respectively. Between 18% (Pickwell et al 1991) and 20% (Karania & Evans 2006) of patients consulting a primary care optometrist have a near heterophoria that has the signs and symptoms indicating that it may be a decompensated heterophoria. Some authors give even higher prevalence figures (Montes 2001), so it could be said that every eyecare practitioner needs to have a working knowledge of binocular vision anomalies (orthoptics). Binocular performance is better than monocular at a wide range of tasks (Sheedy et al 1986).

Comitancy

 

 

 

Ocular deviations can be classified as comitant or incomitant. Comitant

 

 

 

deviations are the same in all directions of gaze for a particular distance of

 

 

 

fixation. Incomitant deviations vary with the direction of gaze; that is, as

 

 

 

the patient moves the eyes to fixate objects in different parts of the field of

 

4

 

fixation, the degree or the angle of the deviation will vary (Ch. 17). There

 

 

may be no deviation in one part of the motor field but a marked deviation