Ординатура / Офтальмология / Английские материалы / Primary Care Ophthalmology_Palay, Krachmer_2005
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Therapeutic Medications |
385 |
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Table 17–16 Antiglaucoma Medications: Carbonic Anhydrase Inhibitors
Generic Name |
Trade Name |
Typical Dosage |
Comments |
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Topical |
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|
Brinzolamide |
Azopt (1%) |
1 drop 3 times a day |
Not as effective as oral preparations |
Dorzolamide |
Trusopt (2%) |
1 drop 3 times a day |
Not as effective as oral preparations |
hydrochloride |
Cosopt |
1 drop twice a day |
Combined with timolol maleate |
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Oral |
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|
Acetazolamide |
Diamox |
250 mg tablet 4 times a day |
Numerous systemic side effects |
|
Diamox Sequel |
500 mg tablet 2 times a day |
Slightly better tolerated |
Methazolamide |
Neptazane |
50 mg tablets 2 times a day |
Not as effective as Diamox but |
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appears to be better tolerated by |
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some patients |
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Prostaglandins. This newer class of agents is used to treat open-angle glaucoma and ocular hypertension. The mechanism of action is to increase uveoscleral outflow, thus reducing intraocular pressure. The most common side effects are hyperemia, an increase in iris pigmentation, and lash growth. These agents have become heavily prescribed, even as monotherapy, due to lack of autonomic side effects and once-daily dosing.
Table 17–17 Antiglaucoma Medications: Prostaglandins
Generic Name |
Trade Name |
Typical Dosage |
|
Comments |
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Bimatoprost |
Lumigan (0.03%) |
1 drop daily (evening) |
} |
Note effects on iris color, |
|
Latanoprost |
Xalatan (0.005%) |
1 drop daily (evening) |
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lashes |
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Travoprost |
Travatan (0.004%) |
1 drop daily (evening) |
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Unoprostone |
Rescula (0.15%) |
1 drop 2 times a day |
|
Not as efficacious |
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Hyperosmotic Agents. Given systemically, hyperosmotic agents increase the osmolality of the blood. This creates an osmotic gradient between the intravascular space and vitreous cavity and effectively pulls fluid from the vitreous into the bloodstream. These medications are used to acutely lower the intraocular pressure in an attack of angle-closure glaucoma and to reduce eye pressure for certain ocular procedures.
Table 17–18 Antiglaucoma Medications: Hyperosmotic Agents
Generic Name |
Trade Name |
Typical Dosage |
Comments |
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Glycerin |
Osmoglyn (50%) |
1-1.5 g/kg |
Antiemetic often required to |
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prevent side effect of vomiting |
Mannitol |
Osmitrol (5%-20%) |
0.5-2 g/kg |
Intravenous drug; adult dose ranges |
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from 20 to 200 g/24 hr |
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386 CHAPTER 17 • Guide to Ophthalmic Medications
Agents for Relief of Allergy Symptoms (Seasonal Allergic Conjunctivitis)
Ocular allergy encompasses a broad spectrum of diseases characterized by a marked type I hypersensitivity response. Exposure to environmental allergens such as animal dander, pollens, and dust can cause symptoms in sensitized individuals. An allergic response is typically characterized by conjunctival injection, chemosis (swelling of the conjunctiva), tearing, eyelid swelling, burning, and ocular and periocular itching. Treatment of allergic ocular disease ideally entails removing the offending agent or modifying the patient’s environment and treating the patient topically to provide symptomatic relief.
Table 17–19 Agents for Relief of Allergy Symptoms
Generic Name |
Trade Name |
Typical Dosage |
Mechanism of Action |
|
|
|
|
Azelastine hydrochloride |
Optivar |
1 drop 2 times a day |
Histamine H1 antagonist |
Cromolyn |
Crolom |
1 drop 4 times a day |
Mast cell inhibitor |
Emedastine difumurate |
Emadine |
1 drop up to 4 times |
H1 antagonist |
|
|
a day |
|
Epinastine hydrochloride |
Elestat |
1 drop 2 times a day |
Antihistamine and mast cell stabilizer |
Ketorolac |
Acular |
1 drop 4 times a day |
NSAID |
Ketotifen |
Zaditor |
1 drop 2 times a day |
Antihistamine and mast cell stabilizer |
Levocabastin |
Livostin |
1 drop 4 times a day |
H1 antagonist |
Lodoxamide |
Alomide |
1 drop 4 times a day |
Mast cell inhibitor |
Naphazoline/antazoline |
Vasocon-A |
1 drop 4 times a day |
Antihistamine/decongestant |
Naphazoline/pheniramine |
Naphcon-A |
1 drop 4 times a day |
Antihistamine/decongestant |
|
Opcon-A |
|
|
Nedocromil |
Alocril |
1 drop 2 times a day |
Mast cell stabilizer |
Olopatadine hydrochloride |
Patanol |
1 drop 2 times a day |
Antihistamine and mast cell stabilizer |
Pemirolast potassium |
Alamast |
1 drop 4 times a day |
Mast cell stabilizer |
|
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|
|
NSAID, nonsteroidal anti-inflammatory drug.
Index
Note: Page numbers followed by f refer to figures (illustrations); page numbers followed by t refer to tables.
A |
Aging—cont’d |
Anterior chamber of eye—cont’d |
|
||
Abducens nerve (sixth cranial nerve), 7, |
and loss of lens elasticity, 128 |
inflammatory cells in |
222 |
and macular degeneration, 173-176, |
as postoperative finding, 181, 182f |
Abducens nerve (sixth cranial nerve) |
174f, 175f |
as sign of corneal ulcer, 111, 112f |
palsy, 32, 222-223 |
and thinning of orbital septum, 67 |
as sign of uveitis, 141, 142f |
signs of, 222, 222f |
AIDS (acquired immunodeficiency |
shallow, penlight demonstration of, |
Abrasion, of cornea, 331-333, 332f |
syndrome), 298 |
194f |
due to conjunctival foreign body, |
ocular lesions associated with, 177, |
slit lamp examination of, 13 |
331, 339, 339f |
298, 299f |
Anterior ischemic optic neuropathy, |
Abscess. See Cellulitis. |
Alkali injury, to eye, 349f, 349-350, |
201-205 |
Abuse (child abuse), ocular signs of, |
350f |
arteritic, 203-205, 204f |
261-262, 262f |
Allen figures, in vision testing of |
nonarteritic, 201-203, 202f |
Acanthamoeba infection, keratitis due to, |
children, 236, 236f |
Anterior scleritis, 47f, 121, 121f, 122f |
44f |
Allergic conjunctivitis, 58, 58f, 59f, 96, |
Anterior uveitis, 140-145 |
Accommodation, 127, 129f |
97f |
ankylosing spondylitis and, 141f, |
age-related changes in, 30, 230, |
treatment of, 59, 96-97 |
293-294 |
230f |
medications used in, 386t |
Behçet’s disease and, 294 |
Accommodative esotropia, 268, |
vs. other conjunctivitides, 36t |
hypopyon accompanying, 141, 142f |
269f |
Alpha agonists, for glaucoma, 383, 383t |
iridal nodules in, 142, 143f |
Acid injury, to eye, 350 |
Amaurosis fugax, 30 |
keratic precipitates associated with, |
Acquired immunodeficiency syndrome |
Amblyopia, 269-271 |
141, 141f |
(AIDS), 298 |
Amiodarone therapy, 317 |
synechiae as signs of, 141, 143f |
ocular lesions associated with, 177, |
ocular problems associated with, 317, |
Antibiotic ocular medications, 375-378, |
298, 299f |
317f, 318 |
376t-378t, 381t |
Acquired nystagmus, 226-227 |
Amsler grid testing, 10-11, 11f |
Antifungal ocular medications, 379, |
Actinic keratosis, 74 |
Anesthetics, 373 |
379t |
eyelid involvement in, 74-75, 75f |
Angiography, 153 |
Antiglaucoma medications, 194, 196, |
Acuity (visual acuity), 2 |
Angioid streaks, in retina, 297 |
382-385, 383t-385t |
measurement of, 2-4 |
Ehlers-Danlos syndrome and, 297, |
Anti-inflammatory ocular medications, |
Snellen charts in, 3f, 4f |
297f, 298 |
380-381, 380t-382t |
refractive power and, 4-6 |
Angle-closure glaucoma, 28, 39-40, |
Antiviral ocular medications, 378, |
Acute angle-closure glaucoma. See |
195-197 |
379t |
Angle-closure glaucoma. |
treatment of, 196 |
Applanation tonometry, 14f, 14-15 |
Adenoviral conjunctivitis, 56 |
laser iridectomy in, 193f, 196 |
Aqueous humor |
in children, 259-260 |
Anisocoria, 216-218 |
flow of, 189, 190f |
Adie’s syndrome, 216, 217f |
Ankylosing spondylitis, 293 |
blockage of. See Angle-closure |
After-cataract, 136, 136f |
anterior uveitis associated with, 141f, |
glaucoma. |
Aging |
293-294 |
leakage of, Seidel test for, 344, |
and cataract formation, 128-131, |
Anterior chamber of eye, 1 |
344f |
130f, 131f |
blood in, 39, 40f, 353f, 353-355 |
Arcus, of cornea, 299, 299f |
and changes in accommodation, 30, |
impaired clearance of, in sickle cell |
Arteritis, giant cell, 203-205 |
230, 230f |
disease, 354 |
optic neuropathy in, 204, 204f |
387
388 |
Index |
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|
|
Bowel disease, inflammatory, 301 |
|
|
Arthritis, rheumatoid, 308 |
Cellulitis |
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ocular problems associated with, |
ocular lesions associated with, 301, |
orbital, 48f, 279f, 279-281, 280f |
||
|
308f, 308-309, 309f |
301f |
pediatric cases of, 263-264 |
|
Artificial tears, 106-107, 375t |
Brain |
preseptal, 49, 275-276, 278-279 |
||
Astigmatism, 5, 5f |
infarct in, and visual loss, 27 |
pediatric cases of, 263-264 |
||
Atrophic (“dry”) age-related macular |
tumor of, and visual loss, 29 |
Central retinal artery occlusion, 162, |
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|
degeneration, 29, 174, 174f, |
Branch retinal artery occlusion, 162. See |
162f. See also Retinal artery, |
|
|
175 |
also Retinal artery, occlusion |
occlusion of. |
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of. |
Central retinal vein occlusion, 167, |
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B |
|
Branch retinal vein occlusion, 167, 168, |
167f, 168, 169 |
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|
168f, 169 |
Chalazion, 50, 51f, 82-83 |
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|
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Bacterial conjunctivitis, 55, 55f, 91f, 92, |
Buckling, scleral, in retinal surgery, 186, |
in children, 266, 267 |
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|
93f, 94 |
187f |
Chemical injury, to eye, 348-351, 349f, |
|
discharge associated with, 55, 55f, |
Bull’s-eye maculopathy |
350f |
||
|
92, 92f, 93f |
in patients receiving chloroquine, |
Chemosis, allergen-induced, 96, 97f |
|
pediatric cases of, 260 |
319, 319f |
Cherry-rod spot, in fovea of retina, as |
||
vs. other conjunctivitides, 36t |
in patients receiving |
sign of arterial occlusion, 17, |
||
Bacterial corneal ulcer, 111, 112f, 113f |
hydroxychloroquine, 325, |
163, 163f |
||
in contact lens wearers, 334, 335f |
325f |
Children. See Pediatric patients. |
||
Basal cell carcinoma, of eyelid, 77f, |
Burn(s), ocular, 348-353, 349f, 350f, |
Chlamydial conjunctivitis, 56-57, |
||
|
77-78 |
352f |
94-95, 95f |
|
Behçet’s disease, 294 |
Burning sensation, ocular, 34 |
laboratory findings in, 95, 96f |
||
ocular lesions in, 294-295 |
Busacca nodules, 142, 143f |
treatment of, 57-58, 95 |
||
Benign essential blepharospasm, 86-87, |
|
vs. other conjunctivitides, 36t |
||
|
87f |
C |
Chloroquine therapy, 318-319 |
|
Beta blockers, for glaucoma, 382, |
ocular problems associated with, 319, |
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383t |
Calcium accumulation, on cornea, 115, |
319f |
|
Binocular diplopia, causes of, 31-33 |
115f |
Cholinergics, for glaucoma, 383, 384t |
||
Blepharitis, 34, 51, 79-81, 98f |
Canalicular injury, 361, 362t |
Choroid, 2, 139, 140f |
||
conjunctivitis and, 97-98 |
Canaliculitis, 284f, 284-285 |
Chronic conjunctivitis, in children, 260 |
||
facial sebaceous gland dysfunction |
Carbonic anhydrous inhibitors, for |
Cialis (tadalafil) therapy, 327 |
||
|
(rosacea) and, 98, 98f |
glaucoma, 384, 385t |
ocular effects of, 328 |
|
infection and, 51, 52f, 80, 80f, 84, |
Carcinoma, of eyelid, 77f, 77-79, 79f |
Ciliary body, 2, 139, 140f |
||
|
85f |
Carotid artery–cavernous sinus fistula, |
Ciliary muscle paralysis, agents |
|
meibomian gland dysfunction and, |
223-224 |
inducing, 374, 374t |
||
|
51, 52f, 81 |
red eye associated with, 65, 65f, |
Coloboma, 254-255, 255f |
|
pediculosis and, 52, 53f |
224f |
Color vision, 11-12 |
||
seborrheic, 51, 51f, 80, 80f |
Cataract(s), 29 |
Confrontation visual field test, 10, 11f |
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Blepharospasm, 86-87, 87f |
congenital, 245-246 |
Congenital eye anomalies, 245-259 |
||
Blindness. See Visual loss. |
and leukocoria, 245, 246f |
Conjunctiva(e), 89, 90f. See also |
||
Blood cells, in anterior chamber of eye, |
cortical, 130, 130f |
Conjunctivitis. |
||
|
39, 40f, 353f, 353-355 |
dense white, 131, 131f |
chemosis of, allergen-induced, 96, |
|
impaired clearance of, in sickle cell |
diabetes mellitus and, 296, 296f |
97f |
||
|
disease, 354 |
laser therapy for, 136, 137f |
examination of, 7, 13 |
|
Blood loss. See Hemorrhage. |
nuclear, 130, 130f |
foreign body in, 339f, 339-341 |
||
Blow-out fracture, orbital, 33, 363-365, |
posterior subcapsular, 131, 131f |
corneal abrasion due to, 331, 339, |
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|
364f |
senile, 128-131, 130f, 131f |
339f |
|
Blue sclera(e) |
surgery for, 132-136, 133f-135f |
growth(s) on or in, 60-62, 62f, |
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in Ehlers-Danlos syndrome, 297f |
opacification following, 136-137 |
98-102, 99f-101f |
||
in osteogenesis imperfecta, 306, 306f |
traumatic, 359f |
extension of, onto cornea, 61, 62f, |
||
Botox therapy, 318 |
Wilson’s disease and, 316 |
113, 114f |
||
management of blepharospasm via, |
Cavernous sinus, fistula between carotid |
HIV infection and, 298, 299f |
||
|
87 |
artery and, 223-224 |
hemorrhagic discoloration of, 337f, |
|
ocular problems associated with, |
red eye associated with, 65, 65f, |
337-339 |
||
|
318 |
224f |
laceration and, 341, 341f |
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Index |
389 |
|
|
|
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Conjunctiva(e)—cont’d |
Contusion, periorbital/ocular, 329-330, |
Cornea—cont’d |
|
inflammation of. See Conjunctivitis. |
330f |
refractive surgery of, 116, 117f |
|
injection (congestion) of |
Copper deposition, sites and signs of, |
ring in |
|
as manifestation of infection, 89, |
in Wilson’s disease, 316, 316f |
as sign of embedded iron foreign |
|
90f, 92f, 95f |
Cornea, 1, 103, 104f |
body, 63, 64f |
|
as sign of uveitis, 141, 141f |
abrasion of, 331-333, 332f |
as sign of Wilson’s disease, 316, |
|
laceration of, 341f, 341-342 |
due to conjunctival foreign body, |
316f |
|
scarring of, in Stevens-Johnson |
331, 339, 339f |
scarring of |
|
syndrome, 312, 312f |
arcus of, 299, 299f |
from herpes simplex virus |
|
slit lamp examination of, 13 |
calcium accumulation on, 115, 115f |
infection, 108f |
|
Conjunctivitis, 35, 36t, 54-58, 89-98 |
chemical injury to, 349f, 350f |
from herpes zoster ophthalmicus, |
|
adenoviral, 56 |
clouding of, mucopolysaccharidosis |
109f |
|
in children, 259-260 |
and, 303, 303f |
in Stevens-Johnson syndrome, |
|
allergic, 58, 58f, 59f, 96, 97f |
contact lens injury to, 40, 43f, |
312, 312f |
|
treatment of, 59, 96-97 |
333-335, 334f, 335f |
slit lamp examination of, 13 |
|
medications used in, 386t |
copper deposition in, 316 |
thermal injury to, 351, 352, 352f |
|
vs. other conjunctivitides, 36t |
cysts of, in patients receiving |
thickness of, 105f |
|
bacterial, 55, 92, 94 |
cytosine arabinoside, 321, |
glaucoma risk in relation to, 191 |
|
discharge associated with, 55, 55f, |
321f |
transplantation of, 116 |
|
92, 92f, 93f |
drying of. See Dry eye. |
sutures used in, 116, 116f |
|
pediatric cases of, 260 |
dystrophies of, 273 |
ulcer of, 28 |
|
vs. other conjunctivitides, 36t |
erosion of, recurrent, 28, 62, 63f, |
bacterial infection and, 111, 112f, |
|
blepharitis and, 97-98 |
114f, 114-115 |
113f |
|
chlamydial, 56-57, 94-95, 95f |
examination of, 13 |
in contact lens wearers, 334, |
|
laboratory findings in, 95, 96f |
excess exposure of, 326 |
335f |
|
treatment of, 57-58, 95 |
myotonic dystrophy and, 304, |
fungal infection and, 111, 113f |
|
vs. other conjunctivitides, 36t |
304f |
herpes simplex virus infection and, |
|
chronic, in children, 260 |
extension of conjunctival growth |
44f |
|
drug allergy and, 58, 59f |
onto, 61, 62f, 113, 114f |
Pseudomonas infection and, in |
|
eye-rubbing and, 59 |
foreign body in or on, 63, 64f, |
contact lens wearers, 334, |
|
herpes simplex virus infection and, |
342-345 |
335f |
|
36t |
movement of, under contact lens, |
rheumatoid arthritis and, 308, |
|
in children, 260 |
334f |
309f |
|
molluscum contagiosum and, 60, 61f |
glue injury to, 358f |
ultraviolet radiation injury to, 332f, |
|
Neisseria gonorrhoeae infection and, 48, |
hyopic injury to, from contact lens, |
336 |
|
49f, 92, 93f |
333 |
vascularization of |
|
in infants, 239, 240, 240f |
infectious lesions of, 40, 43f, 44f, |
blepharoconjunctivitis and, 97, 97f |
|
Neisseria meningitidis infection and, 92 |
107-112 |
herpes simplex virus infection and, |
|
pediatric cases of, 56, 238-240, 240f, |
in contact lens wearers, 334, 335f |
107, 108f |
|
259-261 |
infiltrates in |
verticillate lines on, in patients using |
|
vernal, 58, 58f |
infectious ulcer and, 111, 112f |
amiodarone, 317, 317f |
|
in children, 260 |
subepithelial, secondary to viral |
Cortical cataract, 130, 130f |
|
viral, 55-56, 89, 90f, 91, 91f |
conjunctivitis, 91, 92f |
Corticosteroids |
|
follicular lesions in, 55, 55f, 91, |
inflammation of, 44f, 107-108, 108f |
as anti-inflammatory agents, 380, |
|
91f |
Wegener’s granulomatosis and, |
380t, 381 |
|
pediatric cases of, 259-260 |
315, 315f |
as source of ocular problems, 320 |
|
subepithelial corneal infiltrates |
laceration of, 345-347, 346f |
Cotton-wool spots, on retina, 152, |
|
associated with, 91, 92f |
opacity of, white, 255-257 |
152f, 167f |
|
vs. other conjunctivitides, 36t |
precipitates on |
in AIDS patients, 298 |
|
vs. nasolacrimal duct obstruction, in |
in iritis, 46f |
Cranial nerve palsies. See ordinal cranial |
|
infants, 241, 242f |
in sarcoidosis, 309, 310f |
nerve entries, e.g., Third cranial |
|
Contact dermatitis, 86 |
in syphilis, 313f |
nerve (oculomotor nerve) |
|
eyelid involvement in, 85-86, 86f |
in uveitis, 141, 142f |
palsy. |
|
Contact lens injury, 40, 43f, 333-335, |
recurrent erosion of, 28, 62, 63f, |
Craniopharyngioma, chiasmal |
|
334f, 335f |
114f, 114-115 |
compression by, 215f |
|
390 Index
Crystalline deposition, retinal, in patients using tamoxifen, 326, 327f
Crystalline lens, 1, 127, 128f accommodation by, 127, 129f
age-related changes in, 30, 230, 230f
copper deposition in, 316 examination of, 13
loss of elasticity of, with aging, 128 opacity of. See Cataract(s). subluxation of
syndrome-associated occurrence of, 302, 302f, 373
traumatic, 330f
Cupping, of optic disc, in glaucoma, 189, 191f
Cycloplegics, 374, 374t Cyst(s)
corneal, in patients receiving cytosine arabinoside, 321, 321f
epithelial inclusion, of eyelid, 76f, 76-77
Cytarabine (cytosine arabinoside) therapy, 320
ocular abnormalities correlated with, 321, 321f
Cytomegalovirus infection, retinitis due to, 177-180, 178f
Cytosine arabinoside (Cytarabine) therapy, 320
ocular abnormalities correlated with, 321, 321f
D
Dacryoadenitis, 282-283, 283f, 291, 291f
Dacryocele, in infants, 243, 243f Dacryocystitis, 49, 49f, 281-282,
282f
Degeneration, macular, 26, 29 age-related, 173-176
drusen in, 174, 174f, 175f retinal hemorrhage in, 175, 175f
Dense white cataract, 131, 131f Dermatitis, eyelid involvement in,
84-86, 85f, 86f Dermatomyositis, 295
ocular problems associated with, 295, 295f
Dermoid
corneal, 256, 256f
eyebrow area as site of, 257f
Descemet’s membrane, 103 copper deposition in, 316
Detachment
posterior vitreous, 183 retinal, 26, 183-185
diabetes mellitus and, 155, 155f surgery for, 186
scleral buckling in, 186, 187f tear leading to, 183, 184f
Diabetes mellitus, 296
cataract as complication of, 296, 296f
macular edema associated with, 157-159, 158f
retinopathy in, 153-157 extra-retinal neovascularization
characterizing, 154, 154f complications associated with,
154, 155, 155f Diagnostic medications, 373-374
Diffuse anterior scleritis, 47f, 121, 121f Digoxin toxicity, ocular symptoms of,
321-322 Diplopia, 31
causes of, 31-33 Dislocation, of lens
syndrome-associated occurrence of, 273, 302, 302f
traumatic, 330f Distance acuity chart, 3f
Distorted vision (metamorphopsia), 30 Double vision, 31
causes of, 31-33
Droopy eyelids. See Eyelid(s), drooping of.
Drug allergy, and conjunctivitis, 58, 59f Drug-induced ocular lesions, 317-328 Drusen, 174, 174f, 175f, 211, 212f “Dry” (atrophic) age-related macular
degeneration, 29, 174, 174f, 175
Dry eye, 54, 54f, 103-107, 105f, 106f
artificial tears for, 106-107, 375t punctal plugs in treatment of, 107,
107f
severe, in patients with Sjögren syndrome, 40, 41f, 42f
tear test for, 18, 106 Dystrophy(ies)
corneal, 273 myotonic, 303, 304
ocular lesions associated with, 303-304, 304f
retinal, 273
E
Ectropion, 52, 53f, 67-68, 69f Edema
macular, diabetes mellitus and, 157-159, 158f
optic disc, 208, 209f, 210, 266f Ehlers-Danlos syndrome
angioid streaking of retina in, 297, 297f, 298
blue sclera(e) in, 297f Embolus (emboli), retinal artery
occlusion by, 162, 163f, 164, 165, 165f
treatment of, 166 Emmetropia, 4, 5f Endophthalmitis, 28, 140
endogenous, 183
foreign body as cause of, 45, 47f, 182, 182f
postoperative, 181 trauma and, 182
Entropion, 52, 53f, 68, 69, 70f Epidemic keratoconjunctivitis, 56, 57f Epiretinal membrane, 185f, 185-186 Episclera, 119
Episcleritis, 42, 46f, 120-124, 121f lupus erythematosus and, 314, 314f
Epithelial cyst(s)
of cornea, in patients receiving cytosine arabinoside, 321, 321f
of eyelid, 76f, 76-77
Erectile dysfunction, drugs for, 327 ocular effects of, 328
Erosion, corneal, recurrent, 28, 62, 63f, 114f, 114-115
Erythema, of eyelid(s), 35
in viral conjunctivitis, 89, 91f Erythema multiforme, 311
ocular lesions associated with, 311-312, 312f
Esodeviation, 8, 10f Esotropia, 234, 235f, 267, 268
accommodative, 268, 269f congenital, 251-252
Essential blepharospasm, 86-87, 87f Ethambutol-induced visual loss, 322 Exodeviation, 8, 10f Exophthalmometry, 19, 20f Exophthalmos (proptosis), 37t
thyroid disease and, 285, 285f, 286f
Exotropia, 234, 235f, 267, 268 congenital, 251-252
|
|
Index |
391 |
Exposure, excessive, of cornea, 326 |
Eyelid(s)—cont’d |
|
|
Fourth cranial nerve (trochlear nerve) |
|||
myotonic dystrophy and, 304, 304f |
molluscum contagiosum on, 83-84, |
palsy, 32, 220-222 |
|
Extracapsular cataract extraction, 134 |
84f |
signs of, 220, 221f |
|
Extraocular muscles, 7, 9f, 277f |
port-wine stain on, 250 |
Fovea of retina, 150. See also Macula. |
|
Exudative (“wet”) age-related macular |
seborrheic keratoses on, 73-74, |
cherry-rod spot in, as sign of arterial |
|
degeneration, 26, 174, 175, |
74f |
occlusion, 17, 163, 163f |
|
175f, 176 |
spasm of, 86-87, 87f |
Fracture, orbital, 33, 363-365, 364f |
|
Eye(s). See Ocular entries and structure- |
squamous cell carcinoma of, 78-79, |
Funduscopy, 15-17 |
|
specific citations. |
79f |
color and structural details on, 16, |
|
Eyedrop-related hazards, 20-21 |
swelling of, 35 |
17, 149, 150, 150f, 151f |
|
Eyelash(es), rubbing of, against globe, |
turning in of, 52, 53f, 68, 69, 70f |
Fungal corneal ulcer, 111, 113f |
|
52, 54f, 70, 71f |
turning out of, 52, 53f, 67-68, 69f |
|
|
Eyelid(s), 67, 68f, 69f |
twitching of, 35 |
G |
|
actinic keratoses on, 74-75, 75f |
xanthomas on, 75-76, 76f |
|
|
|
|
||
basal cell carcinoma of, 77f, 77-78 |
|
Giant cell arteritis, 203-205 |
|
carcinoma of, 77f, 77-79, 79f |
F |
optic neuropathy in, 204, 204f |
|
contact dermatitis involving, 85-86, |
Glaucoma, 189-197 |
|
|
|
|
||
86f |
Facial nerve (seventh cranial nerve) |
angle-closure, 28, 39-40, 195-197 |
|
cyst of, 76f, 76-77 |
palsy, as factor in |
treatment of, 196 |
|
dermatitis involving, 84-86, 85f, 86f |
lagophthalmos, 71, 71f |
laser iridectomy in, 193f, 196 |
|
drooping of, 37t, 67, 72, 72f |
and dry eye, 106f |
congenital, 248-249 |
|
congenital, 247f, 247-248 |
Farsightedness (hyperopia), 5, 5f |
medications for, 194, 196, 382-385, |
|
third cranial nerve palsy and, 67, |
Fields of vision, 10 |
383t-385t |
|
219, 219f |
effects of glaucoma on, 189, 192f |
neovascular, 154 |
|
epithelial inclusion cyst of, 76f, |
flashes in, 30 |
open-angle, 29, 190-195 |
|
76-77 |
relation between defects in, and |
treatment of, 194-195 |
|
erythema of, 35 |
lesions of optic nerve or optic |
filtering bleb in, 195, 195f |
|
in viral conjunctivitis, 89, 91f |
chiasm, 199, 200f, 201 |
optic disc cupping in, 189, 191f |
|
examination of, 7, 8f, 11 |
testing of, 10-11, 11f, 20, 21f |
pupillary dilation in, 41f, 196f |
|
eversion and, 7, 8f, 60f |
Fistula, carotid artery–cavernous sinus, |
retinal vein occlusion and, 168 |
|
floppy, 72-73, 73f |
223-224 |
risk of, in relation to corneal |
|
glue injury to, 357, 358 |
red eye associated with, 65, 65f, |
thickness, 191 |
|
heliotrope discoloration of, in |
224f |
visual fields in, 189, 192f |
|
patients with |
Fixation, assessment of, in pediatric |
Glue injury |
|
dermatomyositis, 295, 295f |
patients, 234, 234f |
to cornea, 358f |
|
hemangioma of, in infants, 249, 249f |
Flashes, in visual fields, 30 |
to eyelids, 357, 358 |
|
herpes simplex virus dermatitis |
Flashlight test, of pupillary function, |
Gonioscopy, 18, 18f |
|
involving, 84-85, 85f |
6-7 |
Gonococcal infection, and |
|
inflammation of, 35, 51, 79-81, 98f |
Floaters, 31 |
conjunctivitis, 48, 49f, 92, |
|
conjunctivitis and, 97-98 |
Floppy eyelid syndrome, 72-73, 73f |
93f |
|
facial sebaceous gland dysfunction |
Fluorescein stain, 153, 373 |
in infants, 239, 240, 240f |
|
(rosacea) and, 98, 98f |
Foreign body |
Granulomatosis, Wegener’s, 315 |
|
infection and, 51, 52f, 80, 80f, 84, |
conjunctival, 339f, 339-341 |
ocular lesions associated with, 315f, |
|
85f |
abrasion of cornea by, 331, 339, |
315-316 |
|
meibomian gland dysfunction and, |
339f |
Granulomatous uveitis, sarcoidosis and, |
|
51, 52f, 81 |
corneal, 63, 64f, 342-345 |
309, 310f |
|
pediculosis and, 52, 53f |
movement of, under contact lens, |
|
|
seborrhea and, 51, 51f, 80, 80f |
334f |
H |
|
keratoses on, 73-75, 74f, 75f |
intraocular, 45, 182f, 358-361, 359f, |
|
|
|
|
||
laceration of, 361-363, 362f |
360f |
Halos, around lights, perception of, |
|
louse infestation of, 52, 53f |
endophthalmitis associated with, |
31 |
|
meibomian glands of, 67, 69f |
45, 47f, 182 |
Headache |
|
lesions due to blockage or |
Foreign body sensation, 34 |
migraine, 265 |
|
dysfunction of, 50, 51, 51f, |
Fourth cranial nerve (trochlear nerve), |
visual symptoms of, 30 |
|
52f, 81, 82, 83f |
7, 220 |
pediatric cases of, 264-265 |
|
392 |
|
Index |
|
|
|
|
|
|
|
||
Heliotrope discoloration, of eyelid, in |
Hyperlipidemia, ocular lesions |
Intraepithelial neoplasia, conjunctival, |
|||
|
|
patients with |
associated with, 299f, |
99-100, 100f |
|
|
|
dermatomyositis, 295, 295f |
299-300 |
Intraocular pressure |
|
Hemangioma, in infants, 249f, 249-250 |
Hyperopia (farsightedness), 5, 5f |
measurement of, 14f, 14-15, 15f, |
|||
Hemorrhage. See also Hyphema. |
Hyperosmotic medications, for |
191-192 |
|||
retinal, 17, 152-153 |
glaucoma, 385, 385t |
normal to high, in glaucoma. See |
|||
|
cytomegalovirus infection and, |
Hypertension |
Glaucoma. |
||
|
|
178, 178f |
intracranial, 208, 210 |
Intrauterine infections, and ocular |
|
|
macular degeneration and, 175, |
and headache, in children, 265 |
pathology, 245 |
||
|
|
175f |
and papilledema, 208, 209f, 266f |
Involutional ectropion, 68, 69f |
|
|
posterior uveitis and, 146, 146f |
systemic, and retinopathy, 159-161, |
Involutional entropion, 53f, 68, 70f |
||
|
Roth spot, 176-177, 177f |
300 |
Iridectomy, via laser, for glaucoma, |
||
|
shaken baby syndrome and, 261, |
with arteriolar narrowing, 159, |
193f, 196 |
||
|
|
262f |
160, 160f |
Iridodonesis, in Marfan syndrome, 302 |
|
|
sickle cell disease and, 170, 170f |
Hypertropia, 269 |
Iris (irides), 1, 139, 140f. See also Iritis. |
||
|
venous occlusion and, 167, 167f, |
Hyphema, 39, 353, 353f. See also |
differences between colors of, |
||
|
|
168f |
Hemorrhage. |
258-259 |
|
retrobulbar, 356-357 |
impaired clearance of, in sickle cell |
examination of, 13 |
|||
subconjunctival, 60, 61f, 337f, |
disease, 354 |
neovascularization of, in diabetic |
|||
|
337-339 |
traumatic, 39, 40f, 353-355 |
retinopathy, 154, 154f |
||
|
around conjunctival laceration, |
Hypopyon |
nodules on |
||
|
|
341, 341f |
corneal ulcer and, 111, 112f |
in anterior uveitis, 142, 143f |
|
vitreous, 26, 186 |
postoperative occurrence of, 181, |
in neurofibromatosis, 305, 305f |
|||
Herpes simplex virus infection |
182f |
tremulousness of, in Marfan |
|||
and blepharitis, 84, 85f |
uveitis and, 141, 142f |
syndrome, 302 |
|||
and conjunctivitis, 35t |
|
Iritis, 40, 45f, 46f |
|||
|
in children, 260 |
I |
pediatric cases of, 260 |
||
and dermatitis, 84 |
traumatic, 355-356 |
||||
|
|||||
|
eyelid involvement in, 84-85, |
Idiopathic intracranial hypertension |
Ischemic optic neuropathy, 27, |
||
|
|
85f |
(pseudotumor cerebri), 208, |
201-205 |
|
and iritis, 40, 45f |
210 |
anterior, 201-205 |
|||
and keratitis, 107-108, 108f |
papilledema associated with, 208, |
arteritic, 203-205, 204f |
|||
and ulceration of cornea, 44f |
209f |
nonarteritic, 201-203, 202f |
|||
Herpes zoster ophthalmicus, 108-111, |
In situ keratomileusis, via excimer laser, |
Isoniazid-induced visual loss, 323 |
|||
|
|
109f, 110f |
116, 117f |
Itching, of eyes, 34 |
|
HIV infection and, 298 |
Inclusion cyst, of eyelid, 76f, 76-77 |
|
|||
Hertel exophthalmometry, 19, 20f |
Indocyanine green angiography, 153 |
K |
|||
Heterochromia iridis, 258-259 |
Infants. See Pediatric patients. |
||||
|
|||||
HIV (human immunodeficiency virus) |
Inflammatory bowel disease, 301 |
Kaposi’s sarcoma, on conjunctiva, 298, |
|||
|
|
infection, 298 |
ocular lesions associated with, 301, |
299f |
|
ocular lesions associated with, 177, |
301f |
Kayser-Fleischer ring, 316, 316f |
|||
|
|
298, 299f |
Inflammatory cells |
Keratic precipitates |
|
Hordeolum (stye), 50, 50f, 81-82, 82f |
in anterior chamber of eye |
in iritis, 46f |
|||
in children, 266-267 |
as postoperative finding, 181, 182f |
in sarcoidosis, 309, 310f |
|||
Horner syndrome, 218, 218f |
as sign of corneal ulcer, 111, 112f |
in syphilis, 313f |
|||
Human immunodeficiency virus (HIV) |
in anterior chamber of eye or |
in uveitis, 141, 141f, 142f |
|||
|
|
infection, 298, 299f |
vitreous, as sign of uveitis, |
Keratitis |
|
ocular lesions associated with, 177, |
141, 142f, 145, 146f |
infection and, 44f, 107-108, 108f |
|||
|
|
298, 299f |
Inherited ocular dystrophies, in |
Wegener’s granulomatosis and, 315, |
|
Hutchinson’s sign, 108-109, 109f |
pediatric patients, 273 |
315f |
|||
Hydroxychloroquine (Plaquenil) |
Inherited pigmentary retinopathy, |
Keratoconjunctivitis, epidemic, 56, |
|||
|
|
therapy, 324 |
171-173, 172f |
57f |
|
ocular toxicity of, 324-326, 325f |
Intracranial hypertension, 208, 210 |
Keratoconjunctivitis sicca. See Dry eye; |
|||
Hyopic injury, to cornea, from contact |
and headache, in children, 265 |
Sjogren syndrome. |
|||
|
|
lens, 333 |
and papilledema, 208, 209f, 266f |
Keratomileusis, laser in situ, 116, 117f |
|
|
|
Index |
393 |
|
|
|
|
Keratosis |
Lupus erythematosus, systemic, 314 |
Myasthenia gravis, 33 |
|
actinic, 74 |
ocular lesions associated with, 314, |
ocular, 33, 225f, 225-226 |
|
eyelid involvement in, 74-75, 75f |
314f |
Mydriatics, 374, 374t |
|
seborrheic, eyelid involvement in, |
Luxation, of lens |
Myopia (nearsightedness), 4-5, 5f |
|
73-74, 74f |
syndrome-associated occurrence of, |
severity of, risk of vitreous |
|
Koeppe nodules, 142, 143f |
273, 302, 302f |
detachment correlated with, |
|
|
traumatic, 330f |
183 |
|
L |
|
syndrome-associated occurrence of, |
|
M |
273 |
|
|
|
|
||
Laceration |
Myositis, orbital, 290, 290f |
|
|
|
|
||
of conjunctiva, 341f, 341-342 |
Macula, 151 |
Myotonic dystrophy, 303, 304 |
|
of cornea, 345-347, 346f |
bull’s-eye appearance of |
ocular lesions associated with, |
|
of eyelid, 361-363, 362f |
in patients receiving chloroquine, |
303-304, 304f |
|
of sclera, 347f, 347-348 |
319, 319f |
|
|
Lacrimal apparatus, 275, 277f, 278f. See |
in patients receiving |
N |
|
also Nasolacrimal duct entries |
hydroxychloroquine, 325, |
|
|
|
|
||
and citations beginning with the |
325f |
Nasolacrimal duct, 275 |
|
prefix Dacryo-. |
degeneration of, 26, 29 |
Nasolacrimal duct obstruction, 48-49, |
|
dye test of, 18-19 |
age-related, 173-176 |
281 |
|
Lagophthalmos, 70-71, 71f |
drusen in, 174, 174f, 175f |
pediatric cases of, 241f, 241-244 |
|
and dry eye, 106f |
retinal hemorrhage in, 175, 175f |
treatment of, 242-244, 243f |
|
Large pupil, discrepant in size from |
edema of, in diabetic patients, |
vs. congenital glaucoma, 248 |
|
other pupil, 36, 216-218 |
157-159, 158f |
vs. conjunctivitis, 241, 242f |
|
Laser in situ keratomileusis, 116, 117f |
Marfan syndrome, 302 |
Near acuity chart, 4f |
|
Laser therapy |
ocular lesions associated with, 302, |
Nearsightedness (myopia), 4-5, 5f |
|
for cataract, 136, 137f |
302f |
severity of, risk of vitreous |
|
for glaucoma, 193f, 194, 196 |
Meibomian glands, 67, 69f |
detachment correlated with, |
|
for refractive error, 116, 117f |
lesions due to blockage or |
183 |
|
Leber’s optic neuropathy, 211 |
dysfunction of, 50, 51, 51f, |
syndrome-associated occurrence of, |
|
Lens (contact lens), injury from, 40, |
52f, 81, 82, 83f |
273 |
|
43f, 333-335, 334f, 335f |
Melanoma, conjunctival, 101f |
Necrotizing scleritis, 122, 122f |
|
Lens (crystalline lens), 1, 127, 128f |
Melanosis, racial, 102 |
rheumatoid arthritis and, 308, 308f |
|
accommodation by, 127, 129f |
conjunctival lesion associated with, |
Wegener’s granulomatosis and, |
|
age-related changes in, 30, 230, |
101f, 102 |
315f |
|
230f |
Mellaril (thioridazine) toxicity, and |
Neisseria gonorrhoeae infection, and |
|
copper deposition in, 316 |
pigmentary retinopathy, 323, |
conjunctivitis, 48, 49f, 92, |
|
examination of, 13 |
324f |
93f |
|
loss of elasticity of, with aging, 128 |
Metamorphopsia (distorted vision), 30 |
in infants, 239, 240, 240f |
|
opacity of. See Cataract(s). |
Migraine, 265 |
Neisseria meningitidis infection, and |
|
subluxation of |
visual symptoms of, 30 |
conjunctivitis, 92 |
|
syndrome-associated occurrence |
Molluscum contagiosum, 83 |
Neovascular glaucoma, 154 |
|
of, 302, 302f, 373 |
conjunctivitis associated with, 60, |
Neovascularization, of optic disc and |
|
traumatic, 330f |
61f |
iris, in diabetic retinopathy, |
|
Leukocoria, congenital cataract and, |
eyelid involvement in, 83-84, 84f |
154, 154f |
|
245, 246f |
HIV infection and, 298 |
complications associated with, 154, |
|
Leukoma, 255-257 |
Monocular diplopia, causes of, 32 |
155, 155f |
|
Levitra (vardenafil) therapy, 327 |
Motor system problems, and neuro- |
Nerve, optic. See Optic nerve entries and |
|
ocular effects of, 328 |
ophthlamic disorders, |
Optic disc. |
|
Lice, infestation of eyelids by, 52, 53f |
218-227 |
Nerve fiber layer, of retina, 152, 152f |
|
Light(s) |
Mucopolysaccharidoses, 302-303 |
Nerve palsies. See ordinal cranial nerve |
|
intolerance of, 31 |
ocular lesions associated with, 303, |
entries, e.g., Third cranial nerve |
|
perception of halos around, 31 |
303f |
(oculomotor nerve) palsy. |
|
Lisch nodules, 305, 305f |
“Mutton-fat” keratic precipitates |
Neurofibromatosis, 304 |
|
Louse infestation, of eyelids, 52, 53f |
in sarcoidosis, 309, 310f |
ocular lesions associated with, 305, |
|
Lubricant tears, artificial, 106-107, 375t |
in uveitis, 141, 142f |
305f |
|
394 |
Index |
|
|
|
|
|
Peaked (teardrop) pupil, 254, 255f, |
Neuro-ophthalmic disorders, 199-227 |
Oculomotor nerve (third cranial nerve) |
||
disc pathology in, 201. See also Optic |
palsy, 32, 219-220 |
346, 346f |
|
|
nerve disorders. |
and ptosis, 67, 219, 219f |
Pediatric patients, 229 |
motor system problems and, |
Open-angle glaucoma, 29, 190-195 |
amblyopia in, 269-271 |
|
|
218-227 |
treatment of, 194-195 |
cataracts in, 245-246 |
sensory pathway problems and, 199, |
filtering bleb in, 195, 195f |
chalazion in, 266-267 |
|
|
200f, 201 |
Ophthalmoscopy. See Funduscopy. |
coloboma in, 254-255 |
Nevus (nevi), conjunctival, 100, 101f |
Optic chiasm, lesions of, 213, 215f, |
congenital eye anomalies in, 245-259 |
|
Night blindness, 30 |
215-216 |
conjunctivitis in, 56, 238-240, 240f, |
|
Nodular anterior scleritis, 47f, 121, |
visual field defects due to, 201 |
259-261 |
|
|
122f |
Optic disc, 201 |
esotropia in, 251, 252, 267, 268 |
Nodular episcleritis, 121f |
cupping of, in glaucoma, 189, 191f |
exotropia in, 251, 252, 267, 268 |
|
Nodule(s) |
edema of, 208, 209f, 210, 266f |
glaucoma in, 248-249 |
|
iridal |
neovascularization of, in diabetic |
headache in, 264-265 |
|
|
in anterior uveitis, 142, 143f |
retinopathy, 154, 154f, 155f |
hemangioma in, 249-250 |
|
in neurofibromatosis, 305, 305f |
pallor of, 211 |
heterochromia iridis in, 258-259 |
sarcoid, ocular, 309, 310f |
Optic nerve, 2, 149 |
hordeolum (stye) in, 266-267 |
|
Nonarteritic anterior ischemic optic |
Optic nerve disorders, 201-213 |
inherited ocular dystrophies in, |
|
|
neuropathy, 201-203, |
correlation between visual field |
273 |
|
202f |
defects and, 199, 200f |
iritis in, 260 |
Nonsteroidal anti-inflammatory ocular |
disc pathology in, 201. See also specific |
leukoma in, 255-257, 256f |
|
|
medications, 381, 381t |
abnormalities under Optic disc. |
nasolacrimal duct obstruction in, |
Nuclear cataract, 130, 130f |
infiltrative, 210, 211 |
241f, 241-244, 248 |
|
Nystagmus |
inflammmatory, 27, 205-208, 207f |
nystagmus in, 252-254 |
|
acquired, 226-227 |
ischemic, 27, 201-205, 202f, 204f |
ocular disorders in, 238-273 |
|
pediatric cases of, 252-254 |
neoplastic, 213, 214f |
ocular examination in, 230-238 |
|
|
|
thyroid disease and, 287, 287f |
lid speculum as aid to, 239f |
O |
|
toxic, 211 |
timing of, 23, 231, 232 |
|
traumatic, 211, 365-367 |
ocular trauma in, 261-263, 262f |
|
|
|
||
Ocular disorders. See also particular lesion |
Orbit, 275, 276f |
orbital/preseptal cellulitis in, |
|
|
types and site-specific entries. |
effects of disease of, 45, 48f |
263-264 |
drug-induced, 317-328 |
Orbital blow-out fracture, 33, 363-365, |
port-wine stain in, 250 |
|
pediatric, 238-273. See also specific |
364f |
ptosis in, 247f, 247-248 |
|
|
conditions under Pediatric |
Orbital cellulitis, 48f, 279f, 279-281, |
refractive errors in, 273-275 |
|
patients. |
280f |
retinoblastoma in, 257-258 |
signs and symptoms of, 25-38 |
pediatric cases of, 263-264 |
retinopathy of prematurity in, 231, |
|
syndrome-associated occurrence of, |
Orbital myositis, 290, 290f |
244-245 |
|
|
273 |
Orbital pseudotumor, 33, 288-291 |
strabismus in, 251-252, 267-269 |
systemic disease–related, 293-317 |
classification of, 288-291, 288f-291f |
stye (hordeolum) in, 266-267 |
|
traumatic, 182, 329-367. See also |
Orbital septal thinning, age-related, 67 |
syndrome-associated occurrence of |
|
|
specific types, e.g., Laceration. |
Osteogenesis imperfecta, 306 |
ocular disorders in, |
|
in children, 261-263, 262f |
blue sclerae in, 306, 306f |
273 |
Ocular examination, 1-23 |
|
visual development in, 229 |
|
pediatric, 230-238 |
P |
visual loss in, 269-271 |
|
|
lid speculum as aid to, 239f |
Pediculosis, blepharitis due to, 52, |
|
|
|
||
|
timing of, 23, 231, 232 |
Pain, ocular, 34 |
53f |
Ocular medications, 369-386, |
Pallor, optic disc, 211 |
Penlight demonstration, of shallow |
|
|
370t-386t |
Palsy(ies), cranial nerve. See ordinal |
anterior chamber, 194f |
problems with patients’ consumption |
cranial nerve entries, e.g., Third |
Perimetry, 20, 21f |
|
|
of, 20, 21 |
cranial nerve (oculomotor |
Periorbital contusion, 329-330, 330f |
Ocular trauma, 182, 329-367. See also |
nerve) palsy. |
Phacoemulsification, 133f, 133-134, |
|
|
specific types, e.g., Laceration. |
Panuveitis, 140 |
134f, 135f |
pediatric cases of, 261-263, 262f |
Papilledema, 208, 209f, 210, 266f |
Phenothiazine-induced pigment |
|
Oculomotor nerve (third cranial nerve), |
Patching, of eye, 20, 22f |
deposition, in eye, 323 |
|
|
7, 218-219 |
in pediatric vision testing, 237, 237f |
Photophobia, 31 |
