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1600 John F. Kennedy Blvd.

Ste 1800

Philadelphia, PA 19103-2899

Primary Care Ophthalmology

 

Copyright © 2005, Mosby Inc.

ISBN 0-323-03316-4

All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher.

Permissions may be sought directly from Elsevier’s Health Sciences Rights Department in Philadelphia, PA, USA: phone: (+1) 215 239 3804, fax: (+1) 215 239 3805, e-mail: healthpermissions@elsevier.com. You may also complete your request on-line via the Elsevier homepage (http://www.elsevier.com), by selecting “Customer Support” and then “Obtaining Permissions”.

Notice

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Authors assume any liability for any injury and/or damage to persons or property arising out or related to any use of the material contained in this book.

Previous edition copyrighted 1997

Library of Congress Cataloging-in-Publication Data

Primary Care Ophthalmology / [edited by] David A. Palay, Jay H. Krachmer.—2nd ed. p. ; cm.

Rev. ed. of: Ophthalmology for the primary care physician. c1997.

ISBN 0-323-03316-4

 

 

 

 

1. Eye—Diseases. 2. Ophthalmology.

3.

Primary care (Medicine) I. Palay, David A.

II. Krachmer, Jay H. III. Primary Care Ophthalmology.

[DNLM: 1. Eye Diseases—diagnosis.

2. Eye Diseases—therapy. 3. Primary Health Care. WW 140

O616 2006]

 

 

 

 

RE46.O655 2006

 

 

 

 

617.7¢0232—dc22

 

 

2005041596

 

 

 

Acquisitions Editor: Rolla Couchman

 

 

 

 

Publishing Services Manager: Frank Polizzano

 

 

 

 

Project Manager: Jeff Gunning

 

 

 

 

Design Direction: Ellen Zanolle

 

 

 

 

Cover Designer: Ellen Zanolle

 

 

 

Working together to grow

 

 

 

 

Printed in Hong Kong

 

 

 

libraries in developing countries

 

 

 

www.elsevier.com | www.bookaid.org | www.sabre.org

 

 

 

 

Last digit is the print number: 9 8 7

6

5

4 3 2 1

 

 

 

 

 

 

 

This book is dedicated to

my wife, Debra, my children, Sarah and Matthew, my sister, Deborah, and my parents, Sandra and Bernard,

and is in memory of

Anne and Jacob Kingloff and Israel and Ida Palay.

DAVID A. PALAY

With great love and appreciation I dedicate this book to my wife, Kathryn, our children, Edward, Kara, and Jill, and our parents, Paul and Rebecca Krachmer

and Louis and Gertrude Maraist.

JAY H. KRACHMER

Consulting Editors

Douglas D. Brunette, M.D.

Timothy J. J. Ramer, M.D.

Associate Professor

Assistant Professor

Department of Emergency Medicine

Department of Family Medicine and

University of Minnesota Medical

Community Health

School

University of Minnesota Medical School

Program Director

Minneapolis, Minnesota

Department of Emergency Medicine

 

Hennepin County Medical Center

Robert M. Segal, M.D., M.P.H.

Minneapolis, Minnesota

Clinical Associate Professor

 

Jonathan J. Masor

Department of Pediatrics

University of Minnesota Medical School

Associate Professor of Medicine

Medical Director

Department of Medicine

Inpatient Medical/Surgical Services

Emory University School of Medicine

Children’s Hospitals and Clinics

Atlanta, Georgia

Minneapolis, Minnesota

vii

Contributors

Maria Aaron, M.D.

Assistant Professor of Ophthalmology

Residency Program Director

Emory University School of Medicine

Chief of Service, Ophthalmology

Crawford Long Hospital

Atlanta, Georgia

Allen D. Beck, M.D.

Associate Professor

Department of Ophthalmology

Emory University School of Medicine

Atlanta, Georgia

Michael D. Bennett, M.D.

Associate Professor

Department of Surgery

University of Hawaii John A. Burns

School of Medicine

President

Retina Institute of Hawaii

Honolulu, Hawaii

Douglas M. Blackmon, M.D.

Assistant Clinical Professor of

Ophthalmology

Duke University School of Medicine

Durham, North Carolina

Geoffrey Broocker, M.D.

Professor of Ophthalmology

Emory University School of Medicine

Chief of Service, Ophthalmology

Grady Memorial Hospital

Atlanta, Georgia

Emmett F. Carpel, M.D.

Adjunct Professor

Department of Ophthalmology

University of Minnesota Medical

School

Consultant, Hennepin County Medical

Center

Staff, Phillips Eye Institute

Staff, Health Partners

Minneapolis, Minnesota

Michael C. Diesenhouse, M.D.

Eye Associates of Tucson

Tucson, Arizona

Arlene V. Drack, M.D.

Associate Professor

Department of Ophthalmology

University of Colorado School of

Medicine

University of Colorado Denver

Hospitals and Clinics

Chief, Pediatric Ophthalmology

The Children’s Hospital

Denver, Colorado

Jonathan H. Engman, M.D.

Resident

Department of Ophthalmology

University of Minnesota

Minneapolis, Minnesota

Andrew R. Harrison, M.D.

Assistant Professor

Department of Ophthalmology

University of Minnesota Medical School

Minneapolis, Minnesota

ix

xContributors

Terry Kim, M.D.

Associate Professor of Ophthalmology

Duke University School of Medicine

Associate Director

Cornea and Refractive Surgery Services

Duke University Eye Center

Durham, North Carolina

Jay H. Krachmer, M.D.

Professor and Chairman

Department of Ophthalmology

University of Minnesota Medical School

Minneapolis, Minnesota

Timothy J. Martin, M.D.

Associate Professor of Surgical

Sciences/Ophthalmology

Wake Forest University School of

Medicine/Baptist Medical Center

Winston-Salem, North Carolina

Timothy W. Olsen, M.D.

Associate Professor and William H.

Knobloch Endowed Retina Chair

Department of Ophthalmology

University of Minnesota Medical School

Minneapolis, Minnesota

David A. Palay, M.D.

Associate Clinical Professor

Department of Ophthalmology

Emory University School of Medicine

Atlanta, Georgia

Wayne A. Solley, M.D.

Texas Retina Associates

Dallas, Texas

Ted H. Wojno, M.D.

Professor of Ophthalmology

Emory University School of Medicine

Director of Oculoplastic and Orbital

Surgery

The Emory Clinic

Atlanta, Georgia

Preface

Patients frequently present to primary care practitioners for treatment of an eye problem. It is estimated that greater than half of all eye drops prescribed in the United States are prescribed by physicians other than eye care specialists. It is important that primary care practitioners be able to recognize ophthalmic disease and to treat the problem if necessary, or to refer the patient for further evaluation.

For this second edition we have made several changes and additions:

We have changed the title of the book from Ophthalmology for the Primary Care Physician to Primary Care Ophthalmology, to emphasize that it is intended for anyone involved in direct patient care, including residents, medical students, optometrists, physician assistants, nurses, and nurse practitioners.

We also have added a chapter on the “red eye.” This chapter pulls together material presented throughout the book, to emphasize that a red eye is caused by a variety of conditions, not only by conjunctivitis.

As technology changes, so does the way information is disseminated and shared. This edition of the book contains software that can be downloaded to a personal digital assistant (PDA).

The format of the second edition is the same as that of the first. Most chapters begin with a brief discussion of anatomy, followed by a more detailed description of various diseases. Each disease is described in an outline format that covers symptoms, signs, etiology, workup, differential diagnosis, and treatment. The text describes the core information of each condition, without providing unnecessary details. The highlight of the book is the more than 300 quality color illustrations that accompany the text. Most of the figures underwent a variety of modifications, such as labeling and addition of magnified insets and schematic illustrations, to augment their educational value and to emphasize desired features.

To achieve our goal of providing a practical guide to eye care, we have necessarily omitted a wealth of information that is included in the training of ophthalmologists. Many diseases that are intrinsic to the eye were excluded because the diagnosis and treatment were felt to be outside the realm of the primary care practitioner. The information in this book should not be substituted for a proper referral when necessary.

We tried to be as specific as possible when recommending treatment options. Drug dosages have been checked carefully; however, the reader is urged to consult the Physicians’ Desk Reference or other source when prescribing medications that are unfamiliar.

We hope that this book will continue to serve as a valuable reference to all practitioners involved in delivering primary eye care. We welcome your comments.

David A. Palay, M.D.

Jay H. Krachmer, M.D.

xi

Acknowledgments

We are extremely grateful to our many colleagues, associates, and friends who helped with the preparation of this book. We would like to credit and thank the following sources of material:

Antonio Capone Jr., M.D., Beaumont, Michigan (Figs. 10–28, 10–32, and 15–29) James Gilman, CRA, Atlanta, Georgia (Figs. 1–14 and 9–8)

Glaxo Wellcome (Fig. 1–1)

Harrington DO: The Visual Fields: A Textbook and Atlas of Clinical Perimetry (Fig. 12–1) Edward J. Holland, M.D., Cincinnati, Ohio (Fig. 5–21)

Scott Lambert, M.D., Atlanta, Georgia (Fig. 15–10)

Mark J. Mannis, M.D., Sacramento, California (Fig. 4–16) Daniel F. Martin, M.D., Atlanta, Georgia (Figs. 10–10 and 15–2) Robert A. Myles, CRA, Atlanta, Georgia (Fig. 10–27)

Maria Alexandra Pernetz, B.S., RDCS, Atlanta, Georgia (Fig. 10–17) Dante Pieramici, M.D., Santa Barbara, California (Fig. 9–5)

Spalton DJ, Hitchings RA, Hunter PA: Atlas of Clinical Ophthalmology, ed 2 (Figs. 1–5, 1–7, 1–13, 14–1, and 14–2)

Paul Sternberg Jr., M.D., Nashville, Tennessee (Fig. 10–29)

Ray Swords, CRA, Atlanta, Georgia (Figs. 10–1, 10–18, and 10–26) Keith Walter, M.D., Winston-Salem, North Carolina (Fig. 5–10)

George O. Waring III, M.D., Atlanta, Georgia (Figs. 5–20, 9–2, and 9–9) Watson PG, Ortiz JM: Color Atlas of Scleritis (Fig. 7–1)

xiii

CHAPTER 1

General Eye

Examination

MARIA AARON • WAYNE A. SOLLEY •

GEOFFREY BROOCKER

A structured approach is crucial in the evaluation of patients with ophthalmic complaints. This chapter introduces the primary care physician to a general approach to the eye exam in adult ophthalmic patients. Adherence to these basic steps minimizes the possibility of overlooking a serious ocular problem. (See Chapter 13 for details on the pediatric eye exam.)

Related Anatomy

The cornea is located at the anteriormost aspect of the globe; along with the tear film, it is the major refracting surface of the eye (Fig. 1–1). Directly posterior to the cornea is the anterior chamber, a fluid-filled space (containing the aqueous humor) in which blood, white blood cells, or fibrin may collect in injury, inflammatory disease, and infection. The iris is a pigmented structure that lies just anterior to the crystalline lens and represents the posterior boundary of the anterior chamber. It consists of the sphincter and dilator muscles, connective tissue, and pigmented epithelium. The lens is surrounded by a thin capsule. In cataract surgery (crystalline lens extraction), the capsule usually is left intact posteriorly and houses the intraocular lens implant. The lens is supported by small filaments termed zonules that attach to the periphery of the lens capsule and anchor at the ciliary processes of the ciliary body.

Posterior to the lens is the vitreous body, a clear gel that is firmly attached to the inner eye at the area of the ora serrata (the anterior termination of the retina) and the optic nerve head (optic disc). The wall of the eye (posterior to the cornea) is composed of three layers: the sclera, choroid, and retina. The sclera is a firm collagenous layer that protects the intraocular structures, gives the globe its shape, and is the site

1

2CHAPTER 1 • General Eye Examination

Conjunctiva

Ora serrata

Schlemm's

canal

Anterior chamber

Lens

Cornea

Posterior

chamber

Iris

Ciliary body

Lateral rectus

Sclera

Choroid

Retina

Fovea centralis

Central retinal artery

Central retinal vein

Optic nerve

Medial rectus

FIGURE 1–1 View of the globe, looking down on the right eye, showing major anatomic structures.

of attachment of the extraocular muscles. The choroid is a highly vascular layer forming part of the uveal tract (iris, ciliary body, and choroid) that lies just inside the sclera. The ciliary body controls accommodation, is the site of aqueous production, and lies posterior and lateral to the iris. The retina is located anterior to the choroid and posterior to the vitreous body; it is composed of photoreceptors and neural tissues. The optic nerve is a congregation of approximately 1.2 million axons from the entire retina, and it exits the globe posteriorly and slightly nasally.

The Ocular Examination

Vision

Visual acuity is the principal “vital sign” in ophthalmology. Often the status of the patient’s visual acuity is the first question the ophthalmologist asks the examining physician when consulted. Evaluating the vision should be the first step in the exam, preceding any diagnostic maneuvers (e.g., pupil examination, direct ophthalmoscopy, dilation, intraocular pressure [IOP] evaluation). The examiner measures vision using a standardized visual acuity chart (Fig. 1–2) or near acuity card (Fig. 1–3). If these tools are unavailable, the examiner can use newsprint, the patient’s chart, or an identification badge or a nameplate. The examiner monitors the patient to ensure that no

The Ocular Examination

3

 

 

FIGURE 1–2 Snellen distance acuity chart.

peeking through fingers or around an occluder occurs in an attempt to perform well on the vision “test.” The physician evaluates each eye individually, not only with respect to visual acuity but also in every step of the eye exam. This is especially essential if trauma is involved; occasionally the examining physician directs attention to the obviously injured eye and overlooks the “uninjured” eye.

When documenting visual acuity, the examiner should note whether optical correction (e.g., eyeglasses) was used and which eye was tested. The abbreviation OD (oculus dexter) represents the right eye; OS (oculus sinister), the left eye; and OU (oculus uterque), both eyes. If a standard eye chart is used, the physician notes acuity by the line where most characters are read correctly. The corresponding vision (e.g., 20/20, 20/400) is documented for each eye. This notation is based on a standardized system in which a letter subtends 5 minutes of arc on the retina at a specified distance. For example, a “20/20 E” on a distance chart is designed to subtend 5 minutes of arc on the retina at a distance of 20 feet. A “20/40 E” is designed to subtend an arc of