often, septations in the area of damaged brain (Fig. 11.27).47 MR imaging shows reactive gliomas and tissue injury that are dark on T1-weighted images and bright on T2-weighted images. These findings signify injury to the mature brain, which has acquired the capacity to react to injury with significant astroglial proliferation. Neuro-ophthalmologically, encephalomalacia most often correlates with cortical visual insufficiency associated with hypoxic–ischemic injury to the visual system at term.

Colpocephaly

Colpocephaly was once considered to be a distinct anatomic finding in the brain manifested by occipital horns that are disproportionately enlarged when compared with other parts of the lateral ventricles (Fig. 11.27).389 However, it is really a descriptive term with no inherent diagnostic significance. Colpocephaly is most often seen in association with agenesis of the corpus callosum, and can accompany a variety of degen-