Ординатура / Офтальмология / Английские материалы / Oxford American Handbook of Ophthalmology_Tsai, Denniston, Murray_2011
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16 CHAPTER 1 Clinical skills
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Indicator for beam height |
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Head band |
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Lever for selecting filters |
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Height marker (patient eye level) |
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Control for beam height |
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Lever for selecting magnification |
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Mirror |
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Chin rest |
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Control for chin rest height |
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Tonometer plate |
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Centering screw |
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Control for beam width |
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5° stops |
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Joystick |
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Latch for vertically tilting beam |
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Figure 1.9 Slit lamp with key features identified.
ANTERIOR SEGMENT EXAMINATION (1) 17
Anterior segment examination (1)
Table 1.4 An approach to examining the anterior segment
Observe |
Body habitus, face, orbits |
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Examine lashes. |
Loss, color, position, crusting |
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Examine lid margins. |
Position, contour, skin folds, |
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defects, inflammation, lumps/ |
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bumps |
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Examine palpebral conjunctiva. |
Papillae, follicles, exudate, |
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• Explain, then gently evert the lids. |
membrane, pseudomembrane |
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Examine fornices |
Loss of fornices, symblepharon, |
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ankyloblepharon |
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Examine bulbar conjunctiva/episclera. |
Hyperemia, hemorrhage, lumps/ |
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bumps, degenerations, foreign |
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bodies/deposits |
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Examine sclera.
Examine cornea.
•Use diffuse/direct illumination/ scleral scatter/specular reflection, as required.
Examine anterior chamber.
Hyperemia, thinning, perforation
Diameter, thickness, shape; precorneal tear film, epithelium, Bowman’s layer, stroma, Descemet’s membrane, endothelium
Grade flare/cells/depth; fibrin, pigment, depth
Examine iris.
• Use direct/retroillumination.
Examine lens.
• Use direct/retroillumination.
Examine anterior vitreous.
Color, structure, movement, transillumination defects
Opacity (pattern and maturity), size, shape, position, stability, capsule (anterior and posterior)
Cells, flare, lens-vitreous interface, degenerations
Stain cornea.
• Use fluorescein 9 Rose Bengal.
Check corneal sensation.
• Use topical anesthetic.
Perform applanation tonometry.
Tear film breakup time, Seidel’s test
Consider: gonioscopy, pachymetry, Schirmer’s test
18 CHAPTER 1 Clinical skills
Additional techniques for anterior segment examination
Illumination techniques
Although direct illumination is most commonly used, additional pathology may be revealed by using the following techniques:
•Scleral scatter: Unlock the light source so that the slit beam can be displaced laterally to fall on the limbus while the microscope remains focused on the central cornea. Total internal reflection results in a generalized glow around the limbus and the highlighting of subtle opacities within the cornea, e.g., early edema, deposits, etc.
•Retroillumination: Direct the light source at a relatively posterior reflecting surface (e.g., iris or retina) and focus on the structure of interest (e.g., cornea, or iris and lens). View undilated for iris transillumination defects; view dilated for lens opacities.
•Specular reflection: Focus on the area of interest and change the angle of illumination to highlight discontinuities in an otherwise smooth reflecting surface, e.g., examining the endothelium for guttata.
Tear film breakup time (BUT)
Place a drop of fluorescein into the lower fornix. Ask patient to blink once and then not to blink (or hold lids open if necessary). Observe with blue light the time taken until the tear film breaks up. A result <10 sec is abnormal.
Seidel’s test
Place a drop of 2% fluorescein over the area of concern and observe with the cobalt blue light. The test is positive if there is a luminous green flow of aqueous. This results from local dilution of the stain by aqueous leaking from a surgical wound, penetrating injury or filtering bleb.
Schirmer’s test
Whatman test paper is folded 5 mm from the end and inserted in the temporal fornix of both lower lids. After 5 min, the strips are removed and the length wetted is measured. This result is an indication of basic and reflex tearing. It is normal if >10 mm, borderline at 5–10 mm, and abnormal if <5 mm. Repeating the test after the addition of a topical anesthetic gives an indication of basic secretion alone.
Applanation tonometry
Place a combination of local anesthetic and fluorescein into the lower fornix. Rotate the tonometer dial and record the pressure at which the inner aspect of the two luminous green circles just touch. Usually, the white line on the prism is aligned with the horizontal merdian; however, in high astigmatism, the red line should be aligned with the minor axis. This is also affected by corneal thickness (p. 68).
Tonometer checks and calibration
Goldmann tonometers may be checked by using the metal bar and control weight supplied. With the weight exactly midway along the bar (central stop), the tonometer should read 0 mmHg. The next two stops correspond to 20 and 60 mmHg, respectively. Significant deviation from this indicates a need for formal recalibration by the manufacturer.
ANTERIOR SEGMENT EXAMINATION (2) 19
Anterior segment examination (2)
Anterior chamber (AC) depth measurement
Peripheral AC depth can be estimated using the Van Herick method: set the slit beam at 60° and directed just anterior to the limbus. If the AC depth is less than one-quarter of the corneal thickness, the angle is narrow and should be assessed on gonioscopy. A more central AC depth can be measured with a pachymeter.
Alternatively, use a horizontal beam set at 60 to the viewing arm, and measure the length of beam at which the image on the cornea just abuts the image on the iris. Multiply this by 1.4 to get the depth in mm.
AC reaction
In the presence of AC inflammation, grade both the flare (visible as haze illuminated by the slit-lamp beam; Table 1.5) and cells (seen as particles slowly moving through the beam; Table 1.6). This is important both in detecting intraocular inflammation and in monitoring response to treatment.
Table 1.5 Grading of AC flare
Grade |
Description |
0 |
None |
1+ |
Faint |
2+ |
Moderate (iris + lens clear) |
3+ |
Marked (iris + lens hazy) |
4+ |
Intense (fibrin or plastic aqueous) |
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Reprinted with permission from Jabs DA, et al. SUN Working Group (2005). Am J Ophthalmol 140:509–516.
Table 1.6 Grading of AC cells (counted with 1 x1 mm slit)
Activity |
Cells |
0 |
<1 |
0.5+ |
1–5 |
1+ |
6–15 |
2+ |
16–25 |
3+ |
26–50 |
4+ |
>50 |
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Reprinted with permission from Jabs DA, et al. SUN Working Group (2005). Am J Ophthalmol 140:509–516.
20 CHAPTER 1 Clinical skills
Gonioscopy
Use an indirect (Goldmann, Zeiss) or direct (Koeppe) goniolens to assess the iridocorneal angle, including the iris insertion, the iris curvature, and the angle approach. If the angle is closed, indent (with a Zeiss lens) to see if it can be opened (“appositional closure”) or zippered shut (“synechial closure”). Describe according to the Shaffer (Table 1.7) or Spaeth (Table 1.8) grading system, recording which classification is being used (e.g., “4 = wide open” if using Shaffer) (see Fig. 1.10).
Shaffer classification
Table 1.7 Shaffer classification
Shaffer grade |
Grade 4 |
Grade 3 |
Grade 2 |
Grade 1 |
Grade 0 |
Angular |
40° |
30° |
20° |
10° |
0° |
approach |
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Most posterior |
Ciliary |
Scleral |
Trabeculum |
Schwalbe’s |
Cornea |
structure clearly |
body |
spur |
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line |
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visualized |
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Risk of closure |
Closure |
Closure not |
Closure |
Closure |
Closed |
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not |
possible |
possible |
probable |
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possible |
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Summary |
Wide |
Moderately |
Moderately |
Very |
Closed |
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open |
open |
narrow |
narrow |
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Spaeth classification
Categorize according to iris insertion, angular approach, and iris curvature (e.g., D40R)
Table 1.8 Spaeth classification
Iris insertion |
A |
B |
C |
D |
E |
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Above |
Below |
Below |
Deep |
Extremely |
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Schwalbe’s |
Schwalbe’s scleral spur |
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deep |
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line |
line |
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Angular |
° |
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approach |
Estimate in |
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degrees (°) |
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Iris curvature |
R |
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S |
Q |
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Regular convex |
Steep convex |
Queer (i.e., concave) |
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Ophthalmology of Handbook American Oxford : .C James Tsai, eISBN:9780195393446; 267354567Account:
Ciliary body
Scleral spur
Trabeculum
Schwalbe’s line
Shaffer grade: |
Grade 4 |
Grade 3 |
Grade 2 |
Grade 1 |
Grade 0 |
Most posterior |
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structure seen: |
Ciliary body |
Scleralspur |
Trabeculum |
Schwalbe’s line |
Cornea |
Figure 1.10 Anterior chamber angle with gonioscopic views. See Shaffer classification table for details.
21 GONIOSCOPY
22 CHAPTER 1 Clinical skills
Posterior segment examination (1)
Table 1.9 An approach to examining the posterior segment
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Predilation perform RAPD, |
Amsler testing |
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consider: |
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Observe |
Body habitus, face, orbits |
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Examine iris |
Adequate dilation, aniridia, albinism |
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Examine lens |
Clarity, position, aphakia/pseudophakia |
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Examine vitreous |
Cells, flare, pigment, hemorrhage, opacities, |
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• Use conventional/red-free |
PVD, optical clarity |
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illumination |
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Examine optic disc |
Size, vertical cup:disc ratio, color, flat/ |
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elevated/tilted, neuroretinal rim (inc. contour, |
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notches, hemorrhages), pits/colobomata |
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Examine optic disc margin |
Edema, capillaries, drusen |
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Examine optic disc vessels |
Baring, bayonetting, anomalous vasculature, |
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presence of spontaneous venous pulsation |
Examine peripapillary area
•Use conventional/red-free illumination
Examine macula
Hemorrhages, atrophy, pigmentation, retinal nerve fiber layer defects
Position, flat/elevated, fluid/hemorrhage/ exudate, drusen/atrophy/gliosis, angioid streaks/lacquer cracks, retinal striae/choroidal folds, cherry-red spot
Examine retinal vessels |
Attenuation/dilation, tortuosity, sheathing, |
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emboli, IRMA/ neovascularization/ |
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telangiectasia/shunt vessels |
Examine peripheral fundus |
Degenerations/breaks/retinal detachments/ |
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dialysis/retinoschisis/ fluid/hemorrhage/ |
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exudate; pigmentary retinopathy, chorioretinal |
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scars, tumors, laser/cryotherapy/buckles |
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At the slit lamp, consider choice of lens, Watzke–Allen test.
With the indirect ophthalmoscope, consider choice of lens, scleral indentation.
IRMA, intraretinal microaneurysms; PVD, posterior vitreous detachment; RAPD, relative afferent papillary defect.
Instruments used in posterior segment examination
Slit lamp
Most ophthalmologists examining the posterior segment use the slit lamp with a handheld lens (e.g., 90D).
Optical features
The choice of lens balances the advantages of greater magnification (e.g., 66D lens) against wider field of view (e.g., 90D lens). Some (e.g., superfield/super66) attempt to combine both these qualities.
POSTERIOR SEGMENT EXAMINATION (1) 23
Contact lenses provide the highest clarity and may be useful in assessing detail (e.g., area centralis for macular pathology) or where the view is poor (e.g., media opacities). The retinal view using these lenses is inverted. Three-mirror contact lenses (e.g., Goldmann) facilitate examination of the periphery; the views are mirror image rather than fully inverted.
Method
Ideally, the patient’s eyes are dilated; the fundal view obtained without dilation is usually limited in both extent and stereopsis. Adjust the slit lamp so that it is coaxial and focused on the center of the cornea. Interpose the lens 1 cm in front of the eye and draw the slit lamp back until a clear fundal view is obtained.
To view the peripheral retina, ask the patient to look in the direction of the area you wish to examine (i.e., down to view inferior retina). Troublesome reflections can be reduced by moving the illumination beam slightly off axis.
Indirect ophthalmoscope and scleral indentor
The indirect ophthalmoscope (assisted by scleral indentation) is the instrument of choice for examination of the peripheral fundus.
Optical features
The choice of lens depends on the need for greater magnification (e.g., 3-fold with 20D lens but smaller field of view) vs. wider field of view (e.g., larger field of view with 28D lens but only 2-fold magnification). The retinal view is inverted.
Method
Ensure the patient is well dilated, positioned flat, and looking straight up at the ceiling. Have lens, indenter, and retinal chart/paper (for recording findings) available. Align eyepieces and illumination by viewing your outstretched thumb. Ensure that the headband is sufficiently tight that the ophthalmoscope will remain secure as you move around. Illumination brightness is adjusted according to quality of view and patient comfort.
View from above, with the ophthalmoscope directed downward toward the pupil and with the lens held directly in the line of illumination. Resting this hand lightly against the patient’s face helps steady the lens at an appropriate focal distance for a clear fundal view. To view the peripheral retina, change the angulation by asking the patient to look in the direction of the area to be examined (i.e., down to view inferior retina) while angling your head and lens in the opposite direction.
Scleral indentation
To view, for example, the inferior ora, ask the patient to look straight up and place the indenter on the outside of the lower lid, resting tangentially against the area to be indented. Then ask the patient to look straight down, moving the indenter with the globe. Observe the area of interest while gently exerting pressure over it. Continue for 360°. Warn the patient that the procedure may be uncomfortable.
24 CHAPTER 1 Clinical skills
Posterior segment examination (2)
Instruments used in posterior segment examination (cont.)
Direct ophthalmoscope
For those who see patients in a non-ophthalmic setting, this may be the only option available for fundal examination. Ophthalmologists may also choose to use it where access to a slit lamp or indirect ophthalmoscopy is not possible (e.g., on intensive care unit patients).
•Optical features: There is high magnification (15x) but only a small field of view. The retinal view is not inverted.
•Method: Optimize your view with adequate dilation, dimmed room, and a fully charged ophthalmoscope. The field of view should be maximized by coming very near to the eye. Optimal view of the optic disc is achieved by approaching from 15° to 20° temporally while on the same horizontal level as the patient.
Additional examination techniques for posterior segment examination
Amsler grid
This is viewed at 1 foot. Ask the patient to fixate one eye at a time on the central dot and comment on whether any of the small squares are missing or distorted. There are seven charts, of which chart 1 is suitable for most patients (Table 1.10). It consists of a 20 x 20 grid of 5 mm squares each representing 1° of central field (if viewed at 1 foot).
Watzke–Allen test
While using the slit lamp and handheld lens to view the macula, project a thin strip of light across the fovea. Ask the patient whether the line he/ she sees is broken, narrowed, or complete. A clear gap (Watzke–Allen positive) suggests a full-thickness macular defect or hole.
Goldmann 3-mirror lens
This contact lens is used with the slit lamp to examine the central and peripheral fundus. This is a mirror image rather than a rotated image of the peripheral fundus (cf. standard indirect ophthalmoscopy). It comprises four parts: central (view central 30°), equatorial mirror (largest; views 30° to equator), peripheral mirror (intermediate; views equator to ora), and gonioscopic mirror (smallest; views ora serrata, pars plana and angle).
Retinal charts
One standardized representation of vitreoretinal pathology uses the code presented in Table 1.11.
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POSTERIOR SEGMENT EXAMINATION (2) |
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Table 1.10 Amsler charts |
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Chart |
Design |
Color |
Use |
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1 |
Standard grid |
White on black |
Most patients |
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2 |
Standard grid |
White on black |
Helps fixation |
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with diagonals |
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3 |
Standard grid |
Red on black |
Tests color scotoma, e.g., optic |
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neuropathy, chloroquine toxicity |
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4 |
Random dots |
White on black |
Tests scotoma only (no lines to |
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become distorted) |
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5 |
Horizontal |
White on black |
Tests in one meridian (standard |
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lines |
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horizontal lines) |
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6 |
Horizontal |
Black on white |
Tests in one meridian (standard/ |
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lines |
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fine horizontal lines) |
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7 |
Standard/fine |
White on black |
High sensitivity for central lesions |
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central grid |
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Table 1.11 Retinal chart key
Structure |
Color |
Detached retina |
Blue |
Flat retina |
Red |
Retinal veins |
Blue |
Retinal breaks |
Red within a blue outline |
Retinal thinning |
Red hatching within a blue outline |
Lattice degeneration |
Blue hatching within a blue outline |
Pigment |
Black |
Exudate |
Yellow |
Vitreous opacities |
Green |
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