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Oxford American Handbook of

Ophthalmology

About the Oxford American Handbooks in Medicine

The Oxford American Handbooks are pocket clinical books, providing practical guidance in quick reference, note form. Titles cover major medical specialties or cross-specialty topics and are aimed at students, residents, internists, family physicians, and practicing physicians within specific disciplines.

Their reputation is built on including the best clinical information, complemented by hints, tips, and advice from the authors. Each one is carefully reviewed by senior subject experts, residents, and students to ensure that content reflects the reality of day-to-day medical practice.

Key series features

Written in short chunks, each topic is covered in a two-page spread to enable readers to find information quickly. They are also perfect for test preparation and gaining a quick overview of a subject without scanning through unnecessary pages.

Content is evidence based and complemented by the expertise and judgment of experienced authors.

The Handbooks provide a humanistic approach to medicine—it’s more than just treatment by numbers.

A “friend in your pocket,” the Handbooks offer honest, reliable guidance about the difficulties of practicing medicine and provide coverage of both the practice and art of medicine.

For quick reference, useful “everyday” information is included on the inside covers.

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Oxford American

Handbook of

Ophthalmology

Edited by

James C. Tsai, MD, MBA

Robert R. Young Professor and Chairman

Department of Ophthalmology and Visual Science

Yale University School of Medicine

Chief of Ophthalmology,

Yale-New Haven Hospital

New Haven, Connecticut

Alastair K.O. Denniston, MA,

MRCP, MRCOphth

Clinical Lecturer in Ophthalmology

University of Birmingham, UK

Philip I. Murray, PhD, FRCP,

FRCS, FRCOphth

Professor of Ophthalmology

University of Birmingham, UK

John J. Huang, MD

Associate Professor of Ophthalmology and Visual Science

Director of Clinical Trials and Translational Research,

Yale Eye Center

Director of Uveitis and Ocular Immunology

Yale University School of Medicine

New Haven, Connecticut

Tamir S. Aldad, BA

Predoctoral Research Fellow

Yale University School of Medicine

New Haven, Connecticut

1

3

Oxford University Press, Inc. publishes works that further Oxford University’s objective of excellence

in research, scholarship and education.

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Copyright © 2011 by Oxford University Press, Inc.

Published by Oxford University Press Inc.

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www.oup.com

Oxford is a registered trademark of Oxford University Press

First published 2011

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise,

without the prior permission of Oxford University Press.

Library of Congress Cataloging in Publication Data

Oxford American handbook of ophthalmology / edited by James C. Tsai … [et al.]. p. ; cm.

Other title: Handbook of ophthalmology Includes index.

ISBN 978-0-19-539344-6

1. Ophthalmology—Handbooks, manuals, etc. I. Tsai, James C. II. Title: Handbook of ophthalmology.

[DNLM: 1. Eye Diseases—Handbooks. WW 39] RE48.9.O94 2011

617.7—dc22

2010028006

9 8 7 6 5 4 3 2 1

Printed in China on acid-free paper

This material is not intended to be, and should not be considered, a substitute for medical or other professional advice. Treatment for the conditions described in this material is highly dependent on the individual circumstances. And, while this material is designed to offer accurate information with respect to the subject matter covered and to be current as of the time it was written, research and knowledge about medical and health issues is constantly evolving and dose schedules for medications are being revised continually, with new side effects recognized and accounted for regularly. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulation. Oxford University Press and the authors make no representations or warranties to readers, express or implied, as to the accuracy or completeness of this material, including without limitation that they make no representation or warranties as to the accuracy or efficacy of the drug dosages mentioned in the material. The authors and the publishers do not accept, and expressly disclaim, any responsibility for any liability, loss, or risk that may be claimed or incurred as a consequence of the use and/or application of any of the contents of this material.

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vii

Preface and

Acknowledgments

In this American edition of the popular Oxford Handbook of Ophthalmology, the editors have attempted to retain the essence of the original handbook while incorporating recent advances, current practice patterns, and state-of-the-art concepts in the wide-ranging field of ophthalmic disease. In doing so, we hope that this Handbook provides the eye care provider with timely information that is readily accessible and easy to incorporate into the everyday management of patients. As a rapid reference guide for practicing clinicians, trainees, students, and other ancillary health care professionals, the Oxford American Handbook of Ophthalmology greatly benefits from the expertise of accomplished clinicians in the various subspecialties in ophthalmology.

The editors of the Oxford American Handbook of Ophthalmology would like to express our deepest gratitude to the contributing chapter authors, all of whom are exceptional faculty members practicing in the Department of Ophthalmology and Visual Science at the Yale University School of Medicine. We also acknowledge and appreciate the advice and technical support of Andrea Seils and Staci Hou at Oxford University Press in New York, as well as Angela Luck for her anatomical illustrations. We are indebted to our mentors, colleagues, students, and patients for helping to shape and enhance our clinical and scholarly endeavors. We wish to thank Alastair Denniston and Philip Murray, the authors of the original UK edition of the Oxford Handbook of Ophthalmology, and acknowledge the extraordinary work they did. Finally, we wish to thank our families and friends for their incredible support and encouragement throughout the entire editorial process.

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ix

 

 

Contents

 

 

 

Contributors xi

 

 

 

Symbols and abbreviations xiii

 

 

 

Orthoptic abbreviations xxiii

 

1

 

Clinical skills

 

 

1

2

 

Diagnostic tests and their interpretation

 

 

47

3

 

Trauma

 

 

79

4

 

Lids

 

 

103

5

 

Lacrimal

 

 

127

6

 

Conjunctiva

 

 

135

7

 

Cornea

 

 

159

8

 

Sclera

 

 

217

9

 

Lens

 

 

227

10

Glaucoma

 

261

 

 

 

 

11

Uveitis

 

313

 

 

 

 

12

Vitreoretinal

 

373

13

 

Medical retina

 

 

405

14

 

Orbit

 

 

469

15

Intraocular tumors

 

493

 

 

 

 

16

Neuro-ophthalmology

 

513

 

 

 

 

17

Strabismus

 

571

 

 

 

 

18

Pediatric ophthalmology

 

599

19

 

Aids to diagnosis

 

 

647

20

 

Vision in context

 

 

677