regarding the anterior extent of the lesion and the involvement of anterior segment structures (Fig. 13). This information is particularly important if radioactive plaque treatment is contemplated, because it provides a guide for placement of the anterior margin of the plaque. This information is also helpful if a surgical approach is taken such as iridocyclectomy. Imaging the internal structure of the anterior aspect of the tumor can also provide helpful differential diagnostic information.

FUTURE DIRECTIONS

Ultrasound biomicroscopy provides images in living eyes without affecting the internal relationships of the structures imaged and has proven valuable in clinical practice and research. New methods of using high-frequency ultrasound are in development, including three-dimensional imaging, Doppler42 imaging, and the use of contrast agents. These developments should extend the clinical applications of this technique.

ACKNOWLEDGMENTS

The authors are grateful for the contribution of Michael Sherar, Brian Starkoski, and Kasia Harasiewicz in the development of this imaging system.

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