,.ed 2nd ,Guide Drug Ophthalmologic ,.al et Rhee .J.D 5,-7621-4419-1-1007/978.10 DOI 2011 LLC Media, BusinessþScience Springer
APPENDIX 1: TOPICAL ANTIBACTERIAL SPECTRUM
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Legend: + = sensitive |
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baci = bacitracin |
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gati = gatifloxacin |
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oflox = ofloxacin |
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o = not sensitive |
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CAM = chloramphenicol |
gent = gentamicin |
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poly/trimeth = polymyxin B/trimethoprim |
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i = intermediate activity |
cipro = ciprofloxacin |
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levo = levofloxacin |
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sulfa = sulfacetamide |
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ceph = cephazolin |
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norflox = norfloxacin |
tetra/poly = tetracycline/polymyxin B |
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erythro = erythromycin |
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moxi = moxifloxacin |
tobra = tobramycin |
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FR = fluoroquinolone resistant |
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vanco = vancomycin |
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APPENDIX 1: TOPICAL ANTIBACTERIAL SPECTRUM |
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polymyxin poly/ |
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tetra/ |
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baci cephazolin CAM cipro erythro gati gent levo moxi norflox oflox B |
trimeth |
sulfa poly |
tobra vanco |
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Staph aureus |
+ |
+ |
+ |
+ |
i |
? |
+ |
+ |
? |
+ |
+ |
o |
+ |
+ |
+ |
+ |
+ |
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(MS) |
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Staph aureus FR |
? |
? |
? |
– |
? |
– |
? |
– |
+ |
– |
– |
? |
? |
? |
? |
? |
? |
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Staph |
+ |
i |
o |
+ |
o |
+ |
+ |
+ |
+ |
+ |
+ |
o |
+ |
o |
+ |
+ |
+ |
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epidermadis |
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Staph coag neg |
? |
? |
? |
– |
? |
i |
? |
– |
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i |
– |
– |
? |
? |
? |
? |
? |
? |
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FR |
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Strep. pyogenes |
+ |
+ |
o |
+ |
+ |
+ |
+ |
+ |
+ |
o |
+ |
o |
+ |
o |
+ |
+ |
+ |
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Strep. pneumo |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
I |
o |
+ |
+ |
+ |
+ |
+ |
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Strep viridans |
+ |
+ |
o |
+ |
+ |
+ |
o |
+ |
+ |
o |
I |
o |
+ |
+ |
+ |
+ |
+ |
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Enterococcus |
+ |
o |
o |
i |
o |
? |
o |
+ |
? |
+ |
+ |
o |
+ |
o |
o |
o |
+ |
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faecalis |
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Bacillus cereus |
o |
o |
+ |
o |
+ |
? |
+ |
+ |
? |
+ |
? |
o |
o |
o |
i |
+ |
+ |
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E. coli |
o |
+ |
+ |
+ |
o |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
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o |
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H. influenzea |
o |
+ |
+ |
+ |
i |
+ |
+ |
+ |
+ |
+ |
+ |
o |
+ |
+ |
+ |
+ |
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o |
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Klebsiella |
o |
+ |
+ |
– |
o |
+ |
+ |
+ |
+ |
+ |
I |
+ |
+ |
+ |
+ |
+ |
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o |
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(continued)
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118 |
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APPENDIX 1: TOPICAL ANTIBACTERIAL SPECTRUM (continued ) |
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polymyxin |
poly/ |
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tetra/ |
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baci cephazolin CAM cipro erythro gati gent levo moxi norflox oflox B |
trimeth |
sulfa poly |
tobra vanco |
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Enterobacter |
o |
o |
+ |
+ |
o |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
o |
+ |
o |
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Moraxella |
o |
+ |
+ |
+ |
o |
+ |
o |
+ |
+ |
o |
+ |
o |
o |
o |
o |
o |
o |
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species |
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Neisseria species |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
o |
o |
o |
o |
+ |
i |
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Pseud. |
o |
o |
+ |
+ |
o |
+ |
+ |
+ |
+ |
o |
+ |
i |
i |
i |
+ |
+ |
o |
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aeruginosa |
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Pseud |
? |
? |
? |
– |
? |
– |
? |
– |
– |
– |
– |
? |
? |
? |
? |
? |
? |
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aeruginosa FR |
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Serratia |
o |
o |
+ |
+ |
o |
+ |
+ |
+ |
+ |
o |
+ |
o |
+ |
o |
o |
+ |
o |
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marcescens |
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Aeromonas |
o |
o |
i |
+ |
o |
+ |
+ |
+ |
+ |
+ |
+ |
o |
o |
o |
o |
o |
o |
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Acinetobacter |
+ |
o |
o |
+ |
o |
+ |
+ |
+ |
+ |
+ |
+ |
i |
o |
o |
o |
+ |
o |
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Bacteroides |
o |
o |
+ |
o |
o |
+ |
o |
+ |
+ |
o |
+ |
o |
o |
o |
o |
o |
o |
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fragilis |
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Proprionobacter |
o |
o |
o |
o |
i |
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o |
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o |
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o |
o |
o |
i |
o |
+ |
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acnes |
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Table compiled from information from Physicians Desk Reference for Ophthalmology. 1999. Sanford Guide to Antimicrobial Therapy. 1995. Sanford, JP., Gilbert, DN., Sande, MA, and Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 1990. Gilman, AG., Rall, TW., Nies, AS., Taylor, P. 8th Ed. Pergamon Press., and Manual of Clinical Microbiology. 1995. Murray, PR., Baron, EJ., Pfaller, MA., Tenover, FC., Yolken, RH. 6th Ed. ASM Press. 1995. Graves A, et al. Cornea 2001;3:301–305. Kowalski RP, et al Am J Ophthalmol 2003;136:500–505. Hwang DG. Surv Ophthalmol 2004;49:S79–S83. Mather R, et al. Am J Ophthalmol 2002;133:463–466. Fiscella RG, et al Ophthalmology 1999;106:2286–2290