Gels |
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86 |
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Trade Name |
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Notes |
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GenTeal Lubricant Eye GelO |
contains carbopol 980, claimed to transform from gel to liquid upon contact with the eye |
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Night & Day Tears Again Sterile |
contains povidone 0.1% therefore is not recommended for people with iodine allergies; preserved |
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Lubricant Gel |
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with benzalkonium chloride; not recommended for contact lens wearing patients |
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Viscoelastics |
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SH = sodium hyaluronate |
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adapative: molecules fracture when exposed to high shear rates |
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HMC = hydroxymethylcellulose |
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CS = chondroitin sulfate |
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Cohesive versus |
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Trade Name |
Component |
Viscosity |
Molecular Weight |
Dispersive |
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Amvisc |
1.2% |
SH |
40,000 cSt (62,000 cp+) |
2,000,000 daltons |
cohesive |
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Amvisc Plus |
1.6% |
SH |
55,000 cSt (82,000 cp+) |
1,500,000 daltons |
cohesive |
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BioLon |
1.0% |
SH |
215,000 cpsD |
3,000,000 daltons |
cohesive |
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Cellugel |
2.0% |
HMC |
20,000–40,000 cps |
300,000 daltons |
dispersive |
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CoEase |
1.2% |
SH |
40,000 cps |
1,000,000 daltons |
cohesive |
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DuoVisc |
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EyeVisc |
2.0% HMC |
4,000 cps |
Unknown |
dispersive |
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EyeVisc Plus |
2.0% |
HMC |
40,000 cps |
Unknown |
dispersive |
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EyeVisc SH |
1.4% SH |
50,000 cps |
Unknown |
cohesive |
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Healon |
1.0% |
SH |
200,000 cp+ |
4,000,000 daltons |
cohesive |
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HealonGV |
1.4% |
SH |
2,000,000 cp+ |
5,000,000 daltons |
cohesive |
Healon 5 |
2.3% |
SH |
7,000,000 cp |
4,000,000 daltons |
cohesive |
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possibly |
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adaptive |
LensVisc MC |
2.0% |
HMC |
4,000 mPas |
86,000 daltons |
dispersive |
LensVisc HA |
2.0% |
SH |
>10,000 mPas |
2,300,000 daltons |
cohesive |
Occu-Lon |
1.5% |
SH |
50,000 cps |
2,000,000 daltons |
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Ocucoat |
2.0% |
HMC |
4,000 cp+ |
80,000 daltons |
dispersive |
Provisc |
1.0% |
SH |
135,000 cp+ |
1,900,000 daltons |
cohesive |
STAARVisc II |
1.2% |
SH |
40,000 cps |
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cohesive |
UniVisc |
1.0% |
SH |
Unknown |
3,000,000 daltons |
cohesive |
Viscoat |
3.0% SH and 4% CS |
50,000 cp+ |
22,500 daltons for chondroitin sulfate and |
dispersive |
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in a 3:1 ratio |
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500,000 daltons sodium hyaluronate |
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Vitrax |
3.0 % SH |
35,000 cp+ |
500,000 daltons |
dispersive |
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+37 C shear rate 0/sec (provided by Pharmacia advertisement)
++Measured on Brookfield Digital Cone and Plate Viscometer (provided by CIBA file data) Dprovided by Akorn file data
*37 C measured on Cannon-Fenske Viscometer (provided by Stortz advertisement) **25 C shear rate 2.6/sec (provided by Allergan file data)
***25 C measured on Brookfield Digital Cone and Plate Viscometer (provided by Alcon file data) y25 C measured on Brookfield Digital Cone and Plate Viscometer (provided by Ross file data) yy25 C measured on Brookfield Digital Cone and Plate Viscometer (provided by Fougera file data) ¥Provided by Allergan file data
xShear rate 2/sec (provided by Mentor file data) xxProvided by Shah & Shah IOL Ltd.
#Provided by Bausch & Lomb file data ##Provided by Akorn file data AProvided by Alimera Sciences, Inc.
Lubricants and Viscoelastics 87