8.Mydriatics, Cycloplegics, and Reversal Agents
D.J. Rhee et al., Ophthalmologic Drug Guide, 2nd ed., DOI 10.1007/978-1-4419-7621-5_8,
Springer ScienceþBusiness Media, LLC 2011
78
Drug |
Trade |
Concentration |
Usual Dose/Indication |
Notes |
atropine |
Atropisol, Isopto Atropine, |
Soln, 0.5,1,2,3% |
BID-TID (hyphema/ |
Anti-cholinergic agent |
|
Ocu-tropine |
|
inflammation) |
Duration 7–14 days |
|
Ocu-tropine |
Oint, 1% |
BID-3x/week (inflamm./ |
Useful in infants/children |
|
|
|
pediatric refraction) |
|
cyclopentolate |
AK-Pentolate, Cyclogel |
Soln, 0.5, 1, 2% |
TID-QID |
Anti-cholinergic agent# |
|
Ocu-pentolate, Pentolair |
Soln, 1% |
(inflammation) |
Increased risk of CNS |
|
|
|
|
toxicity (psychotic rxn) in |
|
|
|
|
children |
|
|
|
|
Duration 1–2 days |
dapiprazole |
Rev-Eyes |
Soln, 0.5% |
1 drop (reverse dilation) |
Alpha blocker, reverses |
|
|
|
|
mydriasis from |
|
|
|
|
phenylephrine & to lesser |
|
|
|
|
extent tropicamide |
homatropine |
Isopto Homatropine |
Soln, 2, 5% |
BID-TID |
Anti-cholinergic agent# |
|
|
|
(inflammation) |
Duration 3 days; better for |
|
|
|
|
children |
phenylephrine |
AK-Dilate, Mydfrin, Neo- |
Soln, 2.5, 10% |
1 drop (mydriasis) |
Adrenergic agent |
|
Synephrine, Ocu-phrin |
|
|
Duration 3–5 hours |
|
AK-Nefrin, Ocu-phrin |
Soln, 0.12% |
|
|
scopolamine |
Isopto Hyoscine |
Soln, 0.25% |
BID-TID |
Anti-cholinergic agent# |
|
|
|
(inflammation) |
Duration 3–7 days; better |
|
|
|
|
for children |
tropicamide |
Mydriacyl, Ocu-tropic, |
Soln, 0.5, 1% |
1 drop (cycloplegia) |
Anti-cholinergic agent# |
|
Topicacyl |
|
|
Duration 4–6 hours |
tropicamide/ |
Paremyd |
Soln, 1%/0.25% |
1 drop (mydriasis) |
Anti-cholinergic agent# with |
hydroxyamphetamine |
|
|
|
adrenergic agent |
hydrobromide |
|
|
|
|
scopolamine/ |
Murocoll 2 |
Soln, 0.3/10% |
1 drop (mydriasis) |
Anti-cholinergic agent# with |
phenylephrine |
|
|
|
adrenergic agent |
|
|
|
|
|
#Note: Anti-cholineric agents are cycloplegics
Note: Duration is in the non-inflammed eye. The duration is shorter in the inflammed eye
Mydriatics, Cycloplegics, and Reversal Agents 79