6. Neuro-Ophthalmology
D.J. Rhee et al., Ophthalmologic Drug Guide, 2nd ed., DOI 10.1007/978-1-4419-7621-5_6,
Springer ScienceþBusiness Media, LLC 2011
A. AGENTS USED IN NEURO-OPHTHALMOLOGY |
|
|
66 |
|||
|
|
|
|
|||
|
|
|
|
|||
|
|
|
|
|
|
|
Drug |
Trade |
Preparation |
Usual Dose |
Notes |
||
|
|
|
|
|
|
|
botulinum toxin |
Botox |
Injection |
Varies depending on the entity |
Used in treatment of blepharospasm, |
||
|
|
|
being treated |
strabismus, and hemifacial spasm |
||
cocaine |
N/A |
Soln, 10% |
1 drop, repeat in 1 minute |
Used in diagnosis of Horner’s syndromey |
||
edrophonium |
Tensilon |
IV Soln, |
2–3 mg IV (0.2–0.3 cc)§ |
Used in diagnosis of Myasthenia Gravis; if |
||
chloride |
|
10 mg/ml |
|
unresponsive and no side effects seen |
||
|
|
|
|
after 1 min., may give 0.4 cc Q 30 sec 2 |
||
hydroxyamphetamine |
Paredrine |
Soln, 1% |
1 drop, repeat in 1 minute |
Used in diagnosis of Horner’s syndrome¤ |
||
|
|
|
|
No longer available in US |
||
methylprednisolone |
Solu-Medrol |
IV Soln |
250 mg IV Q 6 hrs |
Treatment of optic neuritis and giant cell |
||
|
|
|
|
arteritis (see below for further |
||
|
|
|
|
discussion) |
||
|
|
|
Special (See Below) |
Traumatic optic neuropathy ‘‘Traumatic |
||
|
|
|
|
optic neuropathy’’ |
||
pilocarpine |
N/A |
Soln, |
1 drop |
Lower strength used in diagnosis and |
||
|
|
0.125% |
|
treatment of Adie’s pupily |
||
§Potential for causing cholinergic crisis, treatment of which includes IV atropine