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Ординатура / Офтальмология / Английские материалы / Ocular Differential Diagnosis 7th edition_Roy_2002

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Nerve)

1. Arteriovenous aneurysms (racemose aneurysms) of the retina (Wyburnâ??Mason syndrome)

2. Bergmeister papilla

3. Cervicooculoacousticus syndrome

4. Down syndrome

5. Drusen of optic nerve (see p. 559)

6. Epipapillary membrane and Bergmeister papilla

7. Fuchs coloboma (partial)

8. Hematoma

9. High hyperopia or astigmatism

10. Juvenile diabetes mellitus (Mauriac syndrome)

11. Medullated nerve fibers (opaque nerve fibers)

12. Normal variant

13. Opacities or haziness of the media, especially nuclear sclerosis of the lens 14. Optic neuritis or papillitis (see p. 578)

15. Peripapillary retinal hemangioma

16. Sarcoidosis (Schaumann syndrome)

17. Tilted disc (partial)

18. Tortuosity and anomalous early branching of the retinal vessels 19. Tumors of disc

A.Gliomas

B.Meningiomas

C.Metastatic

D.Neurinoma

E.Neurofibroma

Catalano RA, Simon JW. Optic disk elevation in Down's syndrome. Am J Ophthalmol 1990;110:28â??32.Bibliographic Links

Perkins ES, Dobree JH. The differential diagnosis of fundus conditions. St. Louis: CV Mosby, 1972.

Diagnostic tables

Unilateral papilledema (swelling of optic disc)

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Bilateral papilledema (swelling of optic disc)

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Peripapillary Subretinal Neovascularization

1. Excessive laser treatment

2. Optic disc drusen

3. Optic nerve coloboma P.598

P.599

P.600

P.601

P.602

4. Presumed histoplasmosis syndrome

5. Presumed sarcoidosis

6. Serpiginous peripapillary choroiditis

Gragoudas ES, Regan CDJ. Peripapillary subretinal neovascularization in presumed sarcoidosis. Arch Ophthalmol1981;99:1194.Bibliographic Links

Yedavally S, Frank RN. Peripapillary subretinal neovascularization associated with coloboma of the optic nerve. Arch Ophthalmol1993;111:552â??553.Bibliographic Links

Pigmented Tumors of Optic Disc

1. Drusen

2. Bourneville syndrome (tuberous sclerosis)

3. Hemangioma of the disc with hemorrhages and secondary pigmentation 4. Malignant melanoma

5. Melanocytomas

6. Metastases

Apple DJ, et al. Congenital anomalies of the optic disc. Surv Ophthalmol

1982;27:3.Bibliographic Links

Pseudoglaucomatus Atrophy of Optic Disc

This condition involves cupping of the nerve head with optic atrophy and field defects simulating true glaucoma but without ocular hypertension.

1. Arteriosclerosis

2. Congenital anomalies of the optic disc

A.Branching of vessels behind the lamina so that the individual branches appear at the disc margins

B.Coloboma within the nerve sheath

C.Congenital coloboma of the optic disc

D.Morning-glory anomaly

E.Oblique insertion of the optic nerve

F.Traction of the disc with bowing of the scleral crescent

3. Giant cell (temporal) arteritis

4. Optic pit

5. Patients using digitalis

6. Reduced blood supply to optic nerve (e.g., acute hypotension, blood loss [severe] carotid insufficiency, gastrointestinal bleeding, ischemic optic neuropathy, myocardial infarction, pernicious anemia)

7. Schnobel cavernous atrophy

8. Syphilitic optic-nerve atrophy

9. Tumors arising near the chiasm

Jonas JB, et al. Pseudoglaucomatous physiologic large cups. Am J Ophthalmol 1989;107:137â??144.Bibliographic Links

Kolker AE, Hetherington J. Becker-Schaffer's diagnosis and therapy of the glaucomas, 6th ed. St. Louis: CV Mosby, 1989.

Moore M, et al. Progressive optic nerve cupping and neural rim decrease in a patient with bilateral autosomal dominant optic nerve colobomas. Am J Opthalmol 2000;129:517â??520.Bibliographic Links

Vaughan D, et al. General ophthalmology, 12th ed. Norwalk, CT: Appleton & Lange, 1989.

P.603

Temporally Displaced Disc (Dragged Disc)

1. Abnormal tortuous retinal vessels temporally

2. Ectopic macula

3. ROP

4. Temporally displaced vessels

Gow J, Oliver GL. Familial exudative vitreoretinopathy. Arch Ophthalmol 1971;86:150â??155.Bibliographic Links

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Visual-Field Defects

Pseudoâ??Visual-Field Defects

1. Facial contour

A.Prominent nose

B.Bushy, projecting eyebrows

C.High cheekbones

D.Ptosis or blepharochalasis

E.Sunken globes

F.Fracture of orbit

2. Corneal opacities

3. Lenticular opacities, especially if miotics are used, will depress fields and exaggerate existing scotomas

4. Aphakia without lens or with convex lens; little distortion with contact lens or intraocular lens

5. Dull patient; patient may be mentally defective, have toxemia, arteriosclerosis, cerebral tumor, brain abscess, or increased intracranial pressure

6. Pupillary size

A. Decrease in miotic field, especially with opacities of ocular media 7. Uncorrected refractive errorsâ??correct for distance testing

8. Head tilting when the head is tilted toward the left shoulder; the right blind spot is elevated; when the head is tilted toward the right shoulder, the right blind spot is lowered

P.605

9. Environmental artifacts

A.Reduction in illumination of screen and test objects magnifies field defect

B.Variation in size of test object changes field defect

C.Standard distance of patient from screen

D.Attention of patient

E.Technique of examiner

10. Psychologic artifacts

A.Patient's misunderstanding of test

B.Tiring of patient by prolonged testing

C.Malingeringâ??isopters at different distances are inconsistent

D. Hysteriaâ??spiral field defects may be found

11. Frames of glasses and segments of multifocal lenses 12. Colored contact lenses

Insler MS, et al. Visual field constriction caused by colored contact lenses. Arch Ophthalmol 1988;106:1680â??1682.Bibliographic Links

Meyer DR, et al. Evaluating the visual field effects of blepharoptosis using automated static perimetry. Ophthalmology 1993;100:651â??659.Bibliographic Links

Pau H. Differential diagnosis of eye diseases, 2nd ed. New York: Thieme Medical, 1988.

Bilateral Central Scotomas

These are bilateral macular defects with decreased visual acuity; scotomas may be central or centrocecal.

1. Bilateral macular lesions, such as cysts or those due to hemorrhage, edema, degeneration, detachment, hole, or infection (see p. 439)

2. Bilateral optic-nerve lesions

A.Papilledema with macular edema (see p. 593)

B.Bipituitary adenoma compressing the prechiasmatic segment of the distal optic nerve

C.Papillitis (see p. 578)

D.Retrobulbar neuritis (see p. 578)

3. Diabetes mellitus

4. Familial optic atrophies (see p. 564) 5. Hyperbaric oxygen

6. Migraineâ??forerunner of visual aurae

7. *Nutritional deficiency, such as thiamine or vitamin B12 deficiency 8. Pernicious anemia

9. Occipital cortex lesions

10. Toxic agents

A.Aromatic aminocompounds and nitrocompoundsâ??aniline, nitrobenzene, trinitrotoluene

B.Carbon disulfide

C.Drugs, including:

acetophenazine

aluminum nicotinate

aspirin

 

(?)

 

acetyldigitoxin

aminosalicylic acid (?)

barbital

adrenal cortex injection

amiodarone

beclomethasone

alcohol

amobarbital

betamethasone

aldosterone

amodiaquine

bromide

alkavervir

antazoline

bromisovalum

allobarbital

aprobarbital

brompheniramine

butabarbital

emetine

nicotinic acid (?)

butalbital

epinephrine

nicotinyl alcohol (?)

butallylonal

ergonovine

ofloxacin

butaperazine

ergot

opium

butethal

ergotamine

oral contraceptives

caramiphen (?)

ethambutol

ouabain

carbinoxamine

ethchlorvynol

oxygen

carbon dioxide

ethopropazine

oxyphenbutazone

carbromal

fludrocortisone

paramethadione

carisoprodol

fluorometholone

paramethasone

carphenazine

fluphenazine

pentobarbital

chloramphenicol

fluprednisolone

perazine

chloroquine

gitalin

pericyazine

chlorpheniramine

heptabarbital

perphenazine

chlorpromazine

hexamethonium

phenobarbital

chlorpropamide (?)

hexethal

piperacetazine

chlortetracycline

hexobarbital

prednisolone

ciprofloxacin

hydrocortisone

prednisone

cisplatin

hydroxychloroquine

primidone

clemastine

ibuprofen

probarbital

clomiphene

indomethacin (?)

prochlorperazine

cobalt (?)

influenza virus vaccine

promazine

contraceptives

interleukin 2, 3, and 6

promethazine

cortisone

iodide and iodine

propiomazine

 

solutions and

 

cyclobarbital

compounds

quinacrine

danazol

iothalamic acid

quinidine

dapiprazole

isoniazid

quinine

hydrochloride

 

 

deferoxamine

lanatoside C

radioactive iodides

demeclocycline

lidocaine

secobarbital

deslanoside

lithium carbonate

sodium

desoxycorticosterone

medrysone

sodium salicylate

dexamethasone

mephobarbital

streptomycin

dexbrompheniramine

meprednisone

sulfacetamide

dexchlorpheniramine

meprobamate

sulfachlorpyridazine

diatrizoate meglumine

mesoridazine

sulfadiazine

and sodium

 

 

 

methacycline

sulfadimethoxine

diazoxide

metharbital

sulfamerazine

diethazine

methdilazine

sulfameter

diethylcarbamazine

methitural

sulfamethizole

digitalis

methohexital

sulfamethoxazole

digitoxin

methotrimeprazine

sulfamethoxypyridazine

digoxin

methoxsalen

sulfanilamide

dimethindene

methyldopa

sulfaphenazole

diphenhydramine

methylergonovine

sulfisoxazole

diphenylpyraline

methylprednisolone

talbutal

diphtheria and tetanus

methysergide

thiamylal

toxoids absorbed

 

 

 

morphine (?)

thiethylperazine

disulfiram

naproxen

thiopental

doxylamine

niacinamide (?)

thiopropazate

thioproperazine

trichloroethylene

trimethadione

thioridazine

trifluoperazine

vinbarbital

thyroid (?)

triflupromazine

 

triamcinolone

trimeprazine

 

 

 

 

P.606

 

 

 

 

 

P.607

 

 

D.Ethyl alcohol

E.Halogenated hydrocarbonsâ??methyl chloride, methyl bromide, iodoform, trichloroethylene

F.Metalsâ??lead, thallium (inorganic), arsenic

G.Methyl alcohol

H.Tobacco

Fraunfelder FT, Fraunfelder FW. Drug-induced ocular side effects. Woburn, MA: Butterworth-Heinemann, 2001.

Harrington DO, Drake MV. The visual fields: text and atlas of clinical perimetry, 6th ed. St. Louis: CV Mosby, 1990.

Karanjia N, Dacobson DM. Compression of the prechiasmatic optic nerve produces a junctional scotoma. Am J Ophthalmol 1999;128,2:256â??258.

Enlargement of Blind Spot

1. Blind spot syndrome (multiple evanescent white-dot syndrome [MEWS]) 2. Coloboma of the optic nerve

3. Drugs, including the following:

 

adrenal cortex injection

ergot

oxytetracycline

 

aldosterone

fludrocortisone

paramethasone

 

betamethasone

fluorometholone

prednisolone

 

carbon dioxide

fluprednisolone

prednisone

 

chlortetracycline

hydrocortisone

quinacrine

 

cortisone

indomethacin (?)

tetracycline

 

demeclocycline

medrysone

triamcinolone

 

desoxycorticosterone

methacycline

trichloroethylene

 

dexamethasone

methylprednisolone

vigabatrin

 

doxycycline

minocycline

vitamin A

4.

Drusen of the optic nerve (see p. 559)

 

5.

Glaucoma

 

 

6.

Inferior conus

 

 

7.

Inverted disc or nasally directed scleral canal

 

8.

Juxtapapillary choroiditis

 

 

9.

Medullated nerve fibers

 

 

10.

Multifocal choroiditis

 

 

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