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Ординатура / Офтальмология / Английские материалы / Ocular Differential Diagnosis 7th edition_Roy_2002

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benoxinate

ferrous gluconate

piperocaine

butacaine

ferrous succinate

polysaccharideâ??iron

 

 

complex

cocaine

ferrous sulfate

proparacaine

colchicine (?)

iodide and iodine solutions

radioactive iodides

 

and compounds

 

dibucaine

 

rifabutin

dyclonine

iron dextran

tetracaine urokinase

ferrocholinate

iron sorbitex

urokinase

ferrous

phenacaine

 

fumarate

 

 

8. Vitreous â??fluff-ballâ?

 

 

9. Following refractive surgery

10. Pseudohypopyon

A.Ghost cell glaucoma with khaki-colored cells

B.Accidental intraocular steroid injection

11. Acute angle-closure glaucoma

12. Non-Hodgkin lymphoma

13. Pars plana vitrectomy and silicone oil injection

Fraunfelder FT, Fraunfelder FW. Drug-induced ocular side effects. Woburn, MA: Butterworth-Heinemann, 2001.

Gabler B, Lohmann CP. Hypopyon after repeated transplantation of human amniotic membrane onto the corneal surface. Ophthalmology 2000;107:1344â??1346.Bibliographic Links

Pau H. Differential diagnosis of eye diseases, 2nd ed. New York: Thieme Medical, 1988.

Recchia FM, et al. Endophthalmitis after pediatric strabismus surgery. Arch Ophthalmol 2000;118:939â??944.Bibliographic Links

Roy FH. Ocular syndromes and systemic diseases, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2002.

Saran BR, et al. Hypopyon uveitis in patients with acquired immunodeficiency syndrome treated for systemic Mycobacterium avium complex infection with rifabutin. Arch Ophthalmol 1994;112;1159â??1161.

Hyphema (Bleeding into the Anterior Chamber)

1. Trauma

A.Following laser iridectomy or strabismus surgery in aphakia

B.Honan balloon use in Fuchs heterochromic iridocyclitis

C.*Tear of ciliary bodyâ??post contusion deformity of anterior chamber

D.*To ciliary body, such as cyclodialysis

E.To iris, such as in iridodialysis or intraocular lens irritation

F.After airbag inflation

G.Metallic intraocular foreign body during magnetic resonance imaging

2. Overdistention of vessels

A.Obstruction of central retinal vein

B.Sudden lowering of high intraocular pressure

3. Fragility of vessel walls

A.Acute gonorrheal iridocyclitis P.332

B.Acute herpes iridocyclitis

C.Acute rheumatoid iridocyclitis

D.Ankylosing spondylitis

4. Blood abnormality

A.Anemias

B.Association with use of aspirin

C.Hemophilia

D.Leukemia

E.Purpura

F.Sickle cell disease

5. Metabolic disease

A.Diabetes mellitus (Willis disease)

B.Scurvy (avitaminosis C)

6. Neovascularization of iris (see rubeosis iridis, p. 366â??367)

7. Vascularized tumors of iris (see pigmented and nonpigmented iris lesions, p. 374â??375)

A.Angioma

B.Iris vascular tufts

C.*Juvenile xanthogranuloma (JXG)

D.Lymphosarcoma

E.Retinoblastoma

8. Wound vascularization following cataract extraction

9. Persistent pupillary membrane hemorrhage

Dahlmann AH, et al. Spontaneous hyphema secondary to iris vascular tufts. Arch Ophthalmol 2001;119:1728â??1729.Bibliographic Links

Gottsch JD. Hyphema: diagnosis and management. Retina 1990;10:65â??72.

Keszel VA, Helveston EM. Hyphema as a complication of strabismus: surgery in an aphakic eye. Arch Ophthalmol 1986;104:637â??638.Bibliographic Links

Roy FH. Ocular syndromes and systemic diseases, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2002.

Ta CN, Bowman RW. Hyphema caused by a metallic intraocular foreign body during magnetic resonance imaging. Am J Ophthalmol 2000;129:533â??534.Bibliographic Links

Spontaneous Hyphema

1. Delayed following glaucoma surgery

2. Diseases of blood or blood vessels

A.Hemophilia

B.Leukemia

C.Malignant lymphoma

D.Purpura

E.Scurvy

3. Fibrovascular membranes in retrolenticular or zonular area

A.Persistent primary vitreous

B.Retinoschisis

C.Retinopathy of prematurity

4. Systemic hypertension

5. Hydrophthalmos

6. Iatrogenic

7. Intraocular neoplasms

8. *JXGâ??yellow nodules of skin and iris

9. Malignant exophthalmos P.333

10. Microbial keratitis, especially Moraxella

11. Occult trauma or trauma with late effect

12. *Rubeosis iridis

13. Severe iritis with or without

A.Behçet disease (dermatostomatoophthalmic syndrome)

B.Diabetes mellitus (Willis disease)

C.Gonococcal infection

D.Herpes zoster or herpes simplex

14. Use of warfarin, heparin, aspirin, or alcohol

15. Vascular anomalies of iris

16. Wound vascularization following cataract extraction

Koehler MP, Shelton DB. Spontaneous hyphema resulting from warfarin. Ann Ophthalmol 1983;15:858â??859.Bibliographic Links

Mason GI, et al. Bilateral spontaneous hyphema arising from iridic microhemangiomas. Ann Ophthalmol 1979;11:87.Bibliographic Links

Ormerod LD, Egan KM. Spontaneous hyphaema and corneal haemorrhages as complications of microbial keratitis. Br J Ophthalmol 1987;71:933.Bibliographic Links

Pandolfi M. Hemorrhages in ophthalmology. New York: Thieme-Stratton, 1979.

Spontaneous Hyphema in Infants

1. Acute rheumatoid iridocyclitis

2. Blood dyscrasias, such as anemia, leukemia, and disseminated intravascular coagulation 3. Iritis

4. *JXG

5. Perinatal asphyxia

6. Persistent hyperplastic primary vitreous

7. Retinoblastoma

8. Retinoschisis

9. Retinopathy of prematurity

10. *Trauma without history (consider child abuse)

Appelboom T, Durso F. Retinoblastoma presenting as a total hyphema. Ann Ophthalmol 1985;17:508â??510.Bibliographic Links

Harley RD, et al. Juvenile xanthogranuloma. J Pediatr Ophthalmol Strabismus 1982;19:33â??39.Bibliographic Links

Ortiz JM, et al. Disseminated intravascular coagulation in infancy and in the neonate. Arch

Ophthalmol 1982;100:1413â??1415.Bibliographic Links

P.334

P.335

P.336

P.337

Diagnostic tables

Spontaneous hyphema

View Table

Spontaneous hyphema in infants

View PDF

P.338

Plasmoid Aqueous (Aqueous with a High Protein Content)

1. Rheumatoid arthritis

2. Serum sickness

3. Infection with gonococcus

4. Following paracentesis or intraocular operation, such as cataract extraction 5. Severe corneal ulceration

6. Trauma

Newell FW. Ophthalmology, principles and concepts, 7th ed. St. Louis: CV Mosby, 1991.

Cholesterolosis of the Anterior Chamber

In this condition, cholesterol crystals develop in the anterior chamber; usually in a blind eye following trauma, but can be associated with hyphema or secondary glaucoma. It is also associated with the following:

1. *Chronic uveitis

2. Eales disease (periphlebitis)

3. Lens subluxation

4. Mature or hypermature cataract

5. Microphthalmia

6. *Phthisis bulbi

7. Retinal detachment

8. Traumatic cataract

9. Vascular disorders

10. Vitreous hemorrhage

Mishra RK, et al. Cholesterol crystals in Eales disease. Indian J Ophthalmol 1980;28:67â??68.Bibliographic Links

Wand M, Garn RA. Cholesterolosis of the anterior chamber. Am J Ophthalmol 1974;78:143â??144.Bibliographic Links

Gas Bubbles in the Anterior Chamber

1. Clostridium perfringens

2. E. coli

3. Yttrium-aluminum-garnet (YAG) laser treatment to the anterior segment 4. Postoperative intraocular surgery

Frantz JF, et al. Acute endogenous panophthalmitis caused by clostridium perfringens. Am J Ophthalmol 1974;78:295â??303.Bibliographic Links

Obertymski H, Dyson C. Clostridium perfringens panophthalmitis. Can J Ophthalmol

1974;9:258â??259.Bibliographic Links

Pigmentation of Trabecular Meshwork

1. In elderly individualsâ??inferior nasal or faint band circumferential

2. *Pseudoexfoliation of lens with or without glaucomaâ??unilateral or bilateral 3. *Pigmentary glaucoma

4. *Krukenberg spindle without glaucoma

5. *Malignant melanomaâ??one eye

6. Cyst of pigment layer of irisâ??unilateral

7. Previous intraocular operation, inflammation, or hyphemaâ??scattered, mostly in lower angle

8. Nevusâ??dense, isolated patch P.339

9. Open-angle glaucomaâ??patchy band, whole circumference 10. Following gamma irradiation for malignancy of nasal sinus

Epstein DL. Chandler and Grant's glaucoma, 3rd ed. Philadelphia: Lea & Febiger, 1986.

Roth M, Simmons RJ. Glaucoma associated with precipitates on the trabecular meshwork.

Ophthalmology 1982;86:1614.

Pigment Liberation into the Anterior Chamber with Dilatation of Pupil

1. Diabetes mellitus (Willis disease)

2. Exercise

3. Hurler disease (mucopolysaccharidoses IH)

4. Low-tension glaucoma with pigment dispersion

Epstein DL. Chandler and Grant's glaucoma, 3rd ed. Philadelphia: Lea & Febiger, 1986.

Ritch R. Nonprogressive low tension glaucoma with pigmentary dispersion. Am J Ophthalmol 1982;94:190â??196.Bibliographic Links

Grading of Anterior Chamber Angle Width (Usually Determined by Gonioscopy)

1. Grade 0: No angle structures visibleâ??narrow angle, complete or partial closure (angle

closure)

2. Grade 1: Unable to see posterior one half of trabecular meshworkâ??extremely narrow angle (probably capable of angle closure)

3. Grade 2: Part of Schlemm canal is visibleâ??moderately narrow angle (may be capable of angle closure)

4. Grade 3: Posterior portion of Schlemm canal is visibleâ??moderately open angle (incapable of angle closure)

5. Grade 4: Ciliary body is visibleâ??open angle (incapable of angle closure)

Epstein DL. Chandler and Grant's glaucoma, 3rd ed. Philadelphia: Lea & Febiger, 1986.

Shields MB. Textbook of glaucoma, 2nd ed. Baltimore: Williams & Wilkins, 1986.

Blood in Schlemm Canal (Reversal of Normal Pressure

Gradient)

1. *Artifact of goniolens flange occluding the episcleral veins in one or more quadrants 2. High episcleral venous pressure

A.*Carotidâ??cavernous sinus fistula (Red-eyed shunt syndrome)

B.*Duralâ??cavernous fistula

C.Mediastinal tumors

D.Orbital arteriovenous fistula

E.Sturgeâ??Weber syndrome (meningocutaneous syndrome)

F.Superior vena cava obstruction (superior vena cava syndrome)

G.Tetralogy of Fallot

3. Low intraocular pressure

A.Following trabeculectomy

B.Hypotony (see p. 325)

C.Intraocular inflammation

4. Normal eye

P.340

Namba H. Blood reflux into anterior chamber after trabeculectomy. Jpn J Ophthalmol 1983;27:616â??625.Bibliographic Links

Phelps CD, et al. Arterial anastomosis with Schlemm's canal. Trans Am Ophthalmol Soc 1985;83:304â??315.Full TextBibliographic Links

Phelps CD, et al. The diagnosis and prognosis of atypical carotid cavernous fistula. Am J Ophthalmol 1982;93:423â??436.Bibliographic Links

Deep Anterior Chamber Angle

1. Normal variation

2. Aphakia

3. Myopia

4. Megalocornea or conical cornea including keratoconus (see p. 288) 5. Congenital glaucoma

6. Posterior dislocation of the lens (see p. 401â??404) 7. Recession of anterior chamber angle

Newell FW. Ophthalmology, principles and concepts, 7th ed. St. Louis: CV Mosby, 1991.

Shields MB. Textbook of glaucoma, 2nd ed. Baltimore: Williams & Wilkins, 1986.

Narrow Anterior Chamber Angle (May be Capable of Angle Closure Glaucoma)

1.

Normal variation

 

 

2.

*Predisposition to angle closure

 

3.

Anterior dislocation of the lens

 

4.

Hyperopia

 

 

5.

Spherophakia and microcornea

 

6.

Postoperative intraocular operation with leaking wound (see hypotony, p. 325)

7.

Choroidal detachment (see p. 532â??535)

 

8.

*Pupillary block

 

 

9.

Loss of aqueous from perforating ulcer, corneal wound, or staphyloma (see hypotony, p.

 

325)

 

 

10.

Intumescent senile cataract

 

 

11.

Traumatic cataract that fluffs up

 

12.

Primary hyperplastic primary vitreous (PHPV)

 

13.

Peripheral anterior synechiae (see p. 341)

 

14.

*Posterior entrapment of aqueous humor (malignant glaucoma or ciliary-block glaucoma)

15.

Drugs, including the following:

 

 

acetazolamide

neostigmine

sulfamethizole

acetylcholine

physostigmine

sulfamethoxazole

 

alpha-chymotrypsin

pilocarpine

sulfamethoxypyridazine

 

demecarium

sulfacetamide

sulfanilamide

 

dichlorphenamide

sulfachlorpyridazine

sulfaphenazole

 

echothiophate

sulfadiazine

sulfapyridine

 

edrophonium

sulfadimethoxine

sulfasalazine

 

ethoxzolamide

sulfamerazine

sulfathiazole

 

isoflurophate

sulfameter

sulfisoxazole

 

methazolamide

sulfamethazine

 

 

 

 

 

 

P.341

 

 

16. Plateau iris

 

 

17. Diffuse ciliary body or iris tumor

Fraunfelder FT, Fraunfelder FW. Drug-induced ocular side effects. Woburn, MA:

Butterworth-Heinemann, 2001.

Newell FW. Ophthalmology: principles and concepts, 7th ed. St. Louis: CV Mosby, 1991.

Taylor BC, Winslow RL. Pseudophakic flat anterior chamber following retinal detachment repair. Ophthalmology 1981;88:935.Bibliographic Links

Irregular Depth of the Anterior Chamber

1. Partial dislocation of lens

2. Tumor of iris or ciliary body

3. Peripheral anterior synechiae on one side of the chamber (see p. 341) 4. Iris bombe or pupillary block

5. Ruptured lens capsule with swelling on one side 6. Anatomic narrowing superiorly

7. Subacute angle-closure glaucoma

8. Cyclodialysis and traumatic recession of chamber angle

Epstein DL. Chandler and Grant's glaucoma, 3rd ed. Philadelphia: Lea & Febiger, 1986.

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