Ординатура / Офтальмология / Английские материалы / Ocular Differential Diagnosis 7th edition_Roy_2002

Corneal Opacification in Infancy (See Conditions Simulating Congenital Glaucoma, p. 305)

1. *Birth trauma, such as Descemet membrane rupture 2. Chromosomal aberrations

A.Mongolism (Down syndrome)â??trisomy 21

B.Trisomy 13 (Patau syndrome)

3. Congenital malformations

A.Amyloidosis (Lubarschâ??Pick syndrome)

B.Anterior chamber cleavage syndromes

1. Axenfeld anomaly

2. Congenital central anterior synechiae

3. Congenital anterior staphyloma

4. *Peter anomaly

5. Rieger anomaly

C.Bilateral corneal dermis-like choristomas

D.Congenital glaucoma

E.De Barsy syndrome

F.*Dermoid tumors

G.*Sclerocornea

H.Xanthomas

4. Corneal dystrophy

A.*Congenital hereditary endothelial dystrophy

B.Congenital hereditary stromal dystrophy

C.Posterior polymorphous dystrophy

5. Idiopathic

6. Inborn errors of metabolism

A.*Mucopolysaccharidoses (MPS)

1. Hurler syndrome (MPS IN)

2. Maroteauxâ??Lamy syndrome (MPS VI)

3. Morquioâ??Brailsford syndrome (MPS IV)

4. Scheie syndrome (MPS IS)

B.Lowe syndrome (oculocerebrorenal syndrome)

C.von Gierke disease (glycogen disease)

D.Corneal lipoidosisâ??later

E.Mucolipidosis

1. Generalized gangliosidosis (GM1-gangliosidosis I and II) 2. ML I (lipomucopolysaccharidosis)

3. ML III (pseudo-Hurler polydystrophy)

F.Rileyâ??Day syndrome (congenital familial dysautonomia) 7. Inflammatory processes

A.Corneal ulceration

B.Herpes simplex and herpes zoster

1. Lowe syndrome (oculocerebrorenal syndrome)

2. Trauma, usually with perforation of the iris

Cibis GW, et al. Corneal keloid in Lowe's syndrome. Arch Ophthalmol 1982;100:1795.Bibliographic Links

Punctate Keratitis or Keratopathy

1. Alimentary disorders

A.Mouth

1. *Dry mouth, as in Sjögren syndrome

2. Ulcers, such as primary herpes, ocular cicatricial pemphigoid, and erythema multiforme

B.Lower alimentary tract

1. Ulcerative colitis as in Sjögren disease

2. Mild colitis, such as that due to an adenovirus

C.Stomach

1. Indigestion as in Sjögren syndrome and acne rosacea

2. Articular diseases

A.Psoriasis arthropathica

B.Reiter disease (polyarthritis enterica)

C.Rileyâ??Day syndrome (congenital familial dysautonomia)

D.Sjögren syndrome (secretoinhibitor syndrome)

3. Conjunctival discharge

A.Mucoid

1. Other types of keratoconjunctivitis sicca

2. Sjögren disease (secretoinhibitor syndrome)

B.Mucopurulent (see p. 186)

1. Angular blepharoconjunctivitis

2. Erythema multiforme (Stevensâ??Johnson syndrome)

3. Gonococcal

4. Inclusion conjunctivitis (acute stage)

5. Meningococcal

6. Reiter disease (polyarthritis enterica)

7. Trachoma

8. Vernal conjunctivitis

C.Serous

1. Adenovirus

2. Herpes simplex

3. Herpes zoster

4. Inclusion conjunctivitis (later)

5. Molluscum contagiosum

6. Trachoma (later)

7. Warts

4. Conjunctival inflammation

A.Cicatrizing (see p. 194)

1. *Ocular cicatricial pemphigoid

2. Chemical burns

3. *Erythema multiforme (Stevensâ??Johnson syndrome)

4. Diphtheria

P.261

5. Fuchsâ??Salzmannâ??Terrien syndrome (allergic reactions from drugs)

6. Radiation burns

7. *Sjögren keratoconjunctivitis sicca

8. Thermal burns

9. Trachoma

B.Diffuse catarrhal 1. Adenovirus

2. Bacterial conjunctivitis

3. Erythema multiforme (Stevensâ??Johnson syndrome)

4. Onchocerciasis syndrome (river blindness)

5. Reiter disease (polyarthritis enterica)

6. Superior limbic keratoconjunctivitis

7. Vaccinia

C.Follicular (see p. 192, 193)

1. Adenovirus

2. Herpes simplex

3. Herpes zoster

4. Inclusion conjunctivitis

5. Molluscum contagiosum

6. Trachoma

D.Giant papillary, such as in vernal and atopic conjunctivitis, and related to contact users, prosthesis, and exposed sutures

E.Papillary

1. Sjögren syndrome (secretoinhibitor syndrome)

2. Trachoma

5. Corneal conditions

A.Deep keratitis, disciform or irregular

1. *Herpes simplex

2. Herpes zoster and other viral diseases

3. Corneal dystrophy (e.g., lattice)

4. Harlequin syndrome

B.Thinned facets because of previous ulcerative or other lesions

1. Acne rosacea (ocular rosacea)

2. Erythema multiforme (Stevensâ??Johnson syndrome)

3. Gorlinâ??Chaudhryâ??Moss syndrome

4. Herpes simplex

5. Sjögren keratoconjunctivitis sicca

C.Vascularization

1. Acne rosacea (ocular rosacea)

2. Molluscum contagiosum

3. Ocular cicatricial pemphigoid

4. Phlyctenular disease (see p. 214)

5. Sjögren keratoconjunctivitis sicca

6. Trachoma

7. Vaccinia

D.Trauma

1. Chemical injury

2. Contact lens related

3. Foreign body under upper eyelid P.262

4. Mild, such as eye rubbing

5. Ultraviolet photokeratopathy

E. Thygeson superficial punctate keratitis (SPK) 6. Diseases of the lids

A.Dermatitis

1. Psoriasis

2. Seborrheic blepharitis

B.Ectropion (see p. 78â??79)

1. Exposure keratopathy

2. Neuroparalytic keratopathy

C.Folliculitis (see p. 94)

1. Blepharitis due to Demodex folliculorum

2. Seborrheic blepharitis

3. Staphylococcal blepharitis

D.Lid retraction (see p. 62â??64)

1. Endocrine exophthalmos

2. *Exposure keratopathy

E.Madarosis, such as that associated with leprosy (stiff immobile lids)

F.Nodules

1. Acne rosacea (ocular rosacea)

2. Molluscum contagiosum

3. Papilloma

4. Warts

G.Trichiasis or entropion with traumatic keratitis