Ординатура / Офтальмология / Английские материалы / Ocular Pathology_6th edition_Yanoff, Sassani_2009

dysplasia, 499

nonchroma n paraganglioma, 561–562

pars planitis, 65, 510

hypoplasia, 498–499

polyclonal gammopathies, 581–583

Pasteurella tularensis (Francisella tularensis), 85,

myopia, 504–505

reticuloendothelial system, 568–571

86

neurofibromatosis, 33

orbital tumors, secondary, 583–585

Patau’s syndrome (trisomy 13; 47,13+),

tuberous sclerosis, 35, 36

organic foreign bodies, 149, 150, 535

38–39, 45

diabetes mellitus, 614, 616, 619–620

organoid nevus syndrome, 201–202

patterned dystrophies of the retinal pigment

glaucoma, 620, 628, 636, 638, 658–660

ornithine, choroidal dystrophy, 348

epithelium, 448

inflammation, 84, 507–513, 619

orthokeratosis, 165, 167

paving stone (cobblestone) degeneration,

nonsurgical trauma, 145, 146

osseous choristoma

422–423, 467

normal anatomy, 497, 498, 499

choroid, 351–353

pedunculated nevus (nevus lipomatosus), 169,

optic disc edema, 96, 122–123, 505–507,

conjunctiva, 240–241, 318–319

240

619, 636

osseous metaplasia, pigment epithelium, 689

Pelizaeus–Merzbacher disease, 447, 452

pits, 503–504

ossification, end stage of di use ocular

pellucid marginal degeneration, 305

proliferative retinopathy, 614, 616

disease, 70

pemphigoid, ocular cicatricial, 229–230

retinoblastoma prognosis, 745–746

osteitis fibrosa cystica, orbit, 541

pemphigus

tumors, 514–522

osteogenesis imperfecta, 314

conjunctivitis, 230

malignant melanoma, 722

osteogenic sarcoma (osteosarcoma), 558

eyelid manifestations, 179

melanocytoma, 721–722

osteoma

pemphigus conjunctivae (ocular cicatricial

optic neuritis, 84, 507–513, 619

choroidal, 351–353

pemphigoid), 229–230

optociliary shunt vessels, 408, 519, 522

orbit, 558

penetrating injuries, 145–147, 148

orange pigment, choroidal melanoma, 719,

osteopetrosis, 457

penetrating keratoplasty, 129–131

720

osteoporosis–pseudoglioma syndrome, 757

perforating injuries, 145–147, 148

orbit, 529–585

oxalosis, 456–457

periarteritis (polyarteritis) nodosa, 182, 513

congenital anomalies, 33–34, 531–532

oxyphilic cell adenoma (oncocytoma), 207,

pericytes, diabetic retinopathy, 602–604

disease, optic neuritis secondary to, 507

243, 244

peripapillary choroidal sclerosis, 347–348

exophthalmos, 529–531, 536, 537

peripheral annular pigmentary dystrophy of

herniated fat, 173

the retina, 491

inflammation, 532–534, 535, 571–573,

p53 gene, 22–23, 560

peripheral chorioretinal atrophy (paving stone

736

pagetoid change, 202

degeneration), 422–423, 467

injuries, 534–535

palisade degeneration of retina, 466–467

peripheral dysgenesis of the cornea and iris,

normal anatomy, 529, 530–532

panophthalmitis, 57, 58, 59

262–264

ocular muscle involvement in systemic

panretinal degeneration, 444–445

peripheral furrow keratitis, 278–279

disease, 536–540

papillary conjunctivitis, 228–229

perivasculitis of the retina, primary (Eales’

tumors see orbital tumors, primary; orbital

papillary syringadenoma (syringocystadenoma

disease), 415

tumors, secondary

papilliferum), 201, 206

persistent fetal vasculature see persistent

varix, 536

papilledema, 505

hyperplastic primary vitreous

vascular disease, 536

papillitis, 506, 511, 513

(PHPV)

orbital tumors, primary, 540–583

papilloma, 190–193, 194

persistent hyperplastic primary vitreous

alveolar soft-part sarcoma, 562–564

conjunctival, 242–243, 245

(PHPV), 334, 482–483, 484,

choristoma, 540–543

lacrimal drainage system, 211, 212

642, 747, 748

classification, 541

papillomaviruses, 176, 199, 211

persistent primary vitreous, 481–482, 483,

endodermal sinus tumor, 564

papillopathy, diabetic, 620

484

granular cell, 562

papillophlebitis, 408

persistent pupillary membrane, 333–334, 335

hamartoma, 543–546, 547

parakeratosis, 165, 167

persistent tunica vasculosa lentis, 334

inflammatory pseudotumor, 571–573

paranasal sinus cysts, 583, 584

Peters’ anomaly, 46, 260–263, 631

lacrimal gland tumors, 564–568

paraneoplastic syndrome (PNS), 436

phacoanaphylactic (phacoimmune)

leukemia, 581, 582

parapapillary chorioretinal atrophy, 660

endophthalmitis (PE), 14,

malignant lymphoma, 573–581

parasitic infections

73–74, 75–76, 122, 129, 130,

malignant melanoma, 719, 722

cornea

384

mesenchymal, 541, 546–558

central ulcers, 273–274

phacolytic glaucoma, 76, 384–385

bone, 557–558

microsporidial keratitis, 266

phakomatoses (disseminated hereditary

cartilage, 557

stromal keratitis, 268–269

hamartoma), 29–36

fatty, 550, 551

granulomatous inflammation, 88–93

glaucoma, 631

fibrous, 550–554

pseudogliomas, 751, 757

meningocutaneous angiomatosis, 30–31

muscle, 554–557, 563–564

skin, 178, 179

neurofibromatosis, 31–34, 314, 514, 519

vascular, 546–549

parietal yolk sac carcinoma see endodermal

tuberous sclerosis, 34–36, 201

monoclonal gammopathies, 581–583

sinus tumor

von Hippel’s disease, 29–30

myxoma, 564

Parinaud’s oculoglandular syndrome, 232

phakomatosis pigmentovascularis (PPV), 631

phlyctenular ulcers, 270

plasma cell hyperplasia, 574

(POHS), 433–434

phosphates, “acute” band keratopathy, 112

plasma cells, 9, 10–13, 14–15, 18, 19, 21

primitive neuroectodermal tumors (PNETs),

photic maculopathy, 155

plasmacytoid cells, 10, 11

560–561

photic retinal toxicity, 106

plasmin, 2

Pringle’s disease (tuberous sclerosis), 34–36,

photorefractive keratectomy (PRK), 131

Plasmodium falciparum, 89–90

201

phototherapeutic keratectomy (PTK), 131

platinum foreign bodies, 147

progressive bifocal chorioretinal atrophy

phthiriasis palpebrarum, 178

platinum (tyrosinase-negative

(PBCRA), 348

Phthirus pubis, 178, 179

oculocutaneous) albinism,

progressive chorioretinal degeneration,

phthisis bulbi, 70, 71

394–395

348–349

phycomycosis (mucormycosis; zygomycosis),

pleomorphic adenoma, 564–565

progressive tapetochoroidal dystrophy,

86

Pneumocystis carinii, 87, 88

348–349

orbital inflammation, 532, 534

polarity, tissue, 168

proliferative vitreoretinopathy (PVR), 127,

Pierre Robin syndrome, 631

polyarteritis (periarteritis) nodosa, 182, 513

494

pigment dispersion syndrome, 647–650,

polyclonal antibodies, 20, 21

Propionibacterium acnes, 116, 121

651

polyclonal gammopathies, orbit, 581–583

proptosis, ocular see exophthalmos

pigment dust, vitreous opacities, 487

polymorphic corneal amyloidosis, 296

prostaglandins, 2

pigment epithelial dystrophy, 448

polymorphonuclear leukocytes (PMNs)

protein kinase C, diabetic retinopathy, 606

pigment epithelium cells, 667

basic principles of pathology

proteinaceous corneal degeneration, 279–282

pigment epithelium-derived factor (PEDF),

acute inflammation, 2, 3, 4

protozoan infections, 88–90

diabetic retinopathy, 606,

staining patterns of inflammation, 15

central corneal ulcers, 273–274

613–614, 615

subacute inflammation, 6, 8

microsporidial keratitis, 266

pigment spots, scleral, 684, 685

familial chronic granulomatous disease of

stromal keratitis, 268

pigmentary glaucoma (pigment dispersion

childhood, 98

psammoma bodies, 522

syndrome), 647–650, 651

suppurative nongranulomatous

psammomatoid ossifying fibroma see juvenile

pigmentation

inflammation, 59, 60, 61

fibromatosis

age-related macular degeneration, 429

polytrichia, 170–171, 225

pseudoadenomatous hyperplasia, 349

basic principles of pathology, 24–25

Pompe’s disease, 455

pseudoepitheliomatous hyperplasia (PEH),

cornea, 235–236, 309–313

Posner–Schlossman syndrome, 645–647

193, 195, 242

drug-induced, 235–236, 311–313

posterior amorphous corneal dystrophy

pseudoexfoliation (PEX) syndrome, 368–373

eyelid manifestations of systemic disease,

(dysgenesis), 298, 307

pseudoglands (Henle), conjunctivitis, 228

188

posterior crocodile shagreen, 298

pseudogliomas, 746–757

iris

posterior embryotoxon (Axenfeld’s anomaly),

Coats’ disease, 751–754, 757

congenital anomalies, 50, 334,

262, 263

discrete retinal/chorioretinal lesions, 757

336–341, 385–387

posterior lenticonus (lentiglobus), 363–364,

endogenous endophthalmitis, 756–757

Fuchs’ heterochromic iridocyclitis, 65,

757

incontinentia pigmenti, 755–756

66

posterior polar cataracts, 363, 364, 365

inflammatory pseudotumour, 757

glaucoma treatment, 655

posterior polymorphous dystrophy (PPMD;

massive neural retinal fibrosis, 756

pigment dispersion syndrome,

hereditary deep dystrophy of

nonattchment of neural retina, 757

647–650, 651

Schlichting), 307, 640

Norrie’s disease, 754–755

lens, 361

posterior scleritis, 317

osteoporosis–pseudoglioma syndrome,

melanoma classification, 711

posterior subcapsular cataracts, 373–374,

757

melanotic tumors see melanotic tumors

376–377

persistent hyperplastic primary vitreous,

neural retinal congenital anomalies,

posterior uveitis

747, 748

394–397

syphilis, 83

retinal astrocytoma, 757

neural retinal detachment, 467, 468

toxoplasmosis, 88

retinal dysplasia, 747–748

nuclear cataracts, 380

postgraft membrane (retrocorneal fibrous

retinopathy of prematurity, 748–751

pseudoexfoliation syndrome, 369

membrane), 130–131

terminology, 746–747

retinal albinotic spots, 423

posttraumatic granulomatous inflammation,

Toxocara endophthalmitis, 751

retinal dystrophies, 445–447, 448

73–76

pseudoinflammation, retinoblastoma, 736

toxic retinal degenerations, 436

foreign-body granuloma, 76

pseudoneoplastic proliferations, 688–689

pigmented lesions, conjunctiva, 248

phacoanaphylactic endophthalmitis, 14,

pseudoneuritis, 499

see also melanotic tumors, conjunctiva

73–74, 75–76, 384

pseudopapilledema, 499, 506

pigmented paravenous chorioretinal atrophy,

sympathetic uveitis, 14, 73–75, 76, 98

pseudophakic glaucoma, 109, 111, 118–120

447

Potter’s syndrome, 50–51

pseudopigmentation, 684

pilar cysts, 189

Prader–Willi syndrome, 338

pseudorheumatoid nodule, 97

pilomatricoma (calcifying epithelioma of

pregnancy, fetal e ects of infections in see

pseudorosette, retinoblastoma, 740

Malherbe), 189, 190

infectious embryopathy

pseudosarcomatous fasciitis see nodular

pingueculae, 237–238, 277

premature babies, retinopathy, 642, 748–751

fasciitis

757

albinism, 394–396, 397

rhegmatogenous, 61, 462–466

pseudoxanthoma elasticum, 450, 451

angiomatosis retinae, 29–30

Wagner-like vitreoretinal

eyelid manifestations, 181

chromosomal aberrations, 38

degenerations, 439

pterygia, 277–278

coloboma, 397–398

diabetes mellitus, 468, 596, 597, 602–618,

ptosis, 171

congenital herpes simplex, 63

620

punctal atresia, 210

dysplasia, 747–748

dystrophies

pupil

foveomacular, 400

hereditary primary, 437–450

atonic, after intraocular surgery, 107

grouped pigmentation (bear tracks),

hereditary secondary, 450–457

iridovitreal adhesions, 483

396–397

glaucoma, 125, 126, 128, 407, 657–658

pseudoexfoliation syndrome, 369

Lange’s fold, 398

hemorrhages, 406–408, 411–412, 413,

sequelae of uveitis, 68, 69

Leber’s congenital amaurosis, 400, 447

492, 610–613

pupillary block glaucoma, 109, 111, 140, 141,

Menkes’ kinky-hair disease, 52

from non-ocular injuries, 153, 154

384, 387

myelinated nerve fibers, 399

uveal leukemia, 354

pupillary membrane, persistent, 333–334, 335

neural retinal cysts, 398–399

vitreous, 493–494

Purtscher’s retinopathy, 153

neurofibromatosis, 33, 34

inflammations, 63, 70, 77, 78, 80, 88,

putrefaction, 24

nonattachment of retina, 398, 757

416–418

Oguchi’s disease, 400

macula, anatomic, 393–394, 395

tuberous sclerosis, 34, 35–36

see also macular degeneration

racemose hemangioma, 351

vitreoretinal, 491–492

massive fibrosis, 756

radial keratotomy, 131, 133

Wyburn-Mason syndrome, 36

nonsurgical trauma, 144–145

radiation dermatosis, 196

see also retina (neural), dystrophies

detachment, 467

radiation (electromagnetic) injuries, 152, 155–

degenerations, 418–437

e ects of non-ocular, 153–154

156, 368, 436

bone marrow transplant retinopathy,

iron deposition, 148, 150

RANTES, 3, 17

436

normal anatomy, 393–394, 395, 396, 595

reactionary retinal glioangiosis, 462

cancer-associated retinopathy,

sarcoidosis, 95, 96

reactive histiocytic disorders, 568–570

436–437, 458

surgical trauma

reactive hyperplasia

degenerative retinoschisis, 420–422

detachment, 117–118, 464–465, 467

Fuchs’, 349–350

idiopathic macular holes, 437

incarceration, 109

idiopathic, 685–686

lattice (palisade), 466–467

photic injury, 106

reactive lymphoid hyperplasia, 573, 574

light energy retinopathy, 155

systemic diseases involving, 457

recurrent nevus, conjunctiva, 679

macular, 122–123, 124, 144, 423–436

tears, 462, 464, 483, 488

red blood cells, 3

microcystoid, 144, 418–420, 421, 422,

toxocariasis, 751

vitreous opacities, 486, 492, 493

607, 610, 612

toxoplasmosis, 89, 90

Reed–Sternberg cells, 581

myopic retinopathy, 423

tumors, 457–462, 463, 685–686, 757

Reese–Ellsworth retinoblastoma classification,

paving stone, 422–423, 467

see also retinoblastoma

733

peripheral retinal albinotic spots, 423

vascular diseases, 400–416

refractive surgery

postirradiation retinopathy, 436

arterial macroaneurysms, 412

cataracts see cataract surgery

toxic, 434–436

arteriolar macroaneurysms, 412

keratoplasty complications, 129–133, 152

traumatic retinopathy, 144–145

arteriolosclerotic retinopathy, 410–411

Refsum’s disease, 447

detachment, 462–470

Coats’ disease, 752–753

Reis–Bücklers corneal dystrophy, 290, 291,

artifactitious, 462, 463

diabetes mellitus, 468, 596, 597,

292–293, 295, 296

classification, 462–466

602–618, 620

Reiter’s syndrome, uveitis, 65–67

Coats’ disease, 751–754

disseminated intravascular coagulation,

relapsing febrile nodular nonsuppurative

complications after surgery for,

415–416

panniculitis, 188

123–129

Eales’ disease (primary perivasculitis of

renal cell carcinoma, 258

congenital (juvenile retinoschisis),

the retina), 415

renal disease, Alport’s syndrome, 363

437–440

exudative retinopathy, 412

renal failure

definitions, 462

hemangioma, 415

conjunctival manifestations, 235

incontinentia pigmenti, 756

hemorrhagic infarction, 406–408, 409

cystinosis, 301–302, 314

after intraocular surgery, 117–118,

hemorrhagic retinopathy, 411–412,

Rendu–Osler–Weber disease, 225

464–465

610–613

reticular dystrophy, 448

major causes, 462

hereditary hemorrhagic telangiectasia,

reticular pseudodrusen, 427–428

malignant melanoma of the choroid,

225

reticuloendothelial system, orbital tumors,

705–706, 716, 718, 720

hypertensive retinopathy, 408–410

541, 568–571

Norrie’s disease, 754, 755

idiopathic macular telangiectasia,

reticulohistiocytoma, 570

pathologic changes after, 467–470

753–754

retina (neural), 393–470

predisposing factors, 466–467

ischemia, 401–406

“cellophane”, 459, 483

retinopathy of prematurity, 751

Leber’s miliary aneurysms, 753

748–751

retinitis pigmentosa, 446

ring abscesses of the cornea, 270

sickle-cell, 412–415

Stargardt’s disease, 441

ring ulcers of the cornea, 270

telangiectasia, 752, 753–754

subneural retinal neovascularization

ringschwiele, 469

vascular supply, 396, 400–401, 596, 597

(CNV), 432

Ritscher–Schinzel syndrome, 631

vitreous opacities, 487

toxic retinal degenerations, 436

Ritter’s disease, 181

retinal angiomatous proliferation (RAP), 432

toxoplasmosis, 89

river blindness, 268–269

retinal arterial macroaneurysms, 412

vitreous hemorrhage, 494

Rochalimaea henselea see Bartonella henselae

retinal arteriolar macroaneurysms (RAMs),

retinal pits, 467

Rosai–Dorfman disease see sinus histiocytosis

412, 413

retinal septum, congenital (posterior PHPV),

Rosenthal fibers, 517, 518

retinal arteriolar tortuosity, 400

482–483, 484

rosettes

retinal artery occlusion, 402–403, 404, 406

retinal vein occlusion, 406–408, 409

retinal dysplasia, 748

retinal capillary microaneurysms (RCMs),

retinitis, 416, 417–418

retinoblastoma, 739, 740, 741, 745

604–605, 608

as pseudoglioma, 757

Roth’s spots, 412, 416

retinal detachment see retina (neural),

viral, 77, 78, 416, 418

rubella, congenital syndrome, 43–44

detachment

retinitis pigmentosa, 445–447, 689

rubella endophthalmitis, 121–122

retinal ganglion cells (RGCs), glaucoma,

retinitis proliferans, 617

rubeosis iridis, 344, 600

657–658

retinitis punctata albescens, 444–445

see also iris, neovascularization

retinal pigment epithelium (RPE)

retinitis sclopetaria, 144

Russell bodies, 11, 12, 583

age-related macular degeneration, 429–

retinoblastoma, 733–746

430, 431–432

age at diagnosis, 733–734

amyotrophic lateral sclerosis/

clinical features, 736–737, 738

salivary gland disease, 77–78

parkinsonism–dementia

conditions simulating, 746–757

salmon-patch choroidopathy, di use

complex (ALS/PDC) of Guam,

genetics, 734–736, 745, 746

inflammatory, 417

418

histology, 738–745

salmon-patch hemorrhages, 413–414

Best’s disease, 442, 443

incidence, 733

Salzmann’s nodular degeneration, 282–283

Bietti’s crystalline dystrophy, 449

necrosis, 59

Sanfilippo’s syndromes, 300

choroidal coloboma, 339

spontaneous regression, 744

sarcoidosis, 14, 93–96

choroidal dystrophies, 347, 348, 349

trilateral, 734, 746

Schaumann bodies, sarcoidosis, 96

choroidal melanoma invasion, 719–720

uveal extension, 355

Scheie’s syndrome, 300

congenital anomalies

visual prognosis, 733

Schilder’s disease, 452, 511, 512

chromosomal aberrations, 45

vitreous opacities, 487

schistosomiasis, 92–93

coloboma, 398

retinochoroiditis

Schlemm’s canal, 625, 627, 629–630, 632,

congenital herpes simplex, 63

as pseudoglioma, 757

636, 637, 638

congenital rubella syndrome, 43, 44

toxoplasmic, 88

Schnabel’s optic atrophy, 659–660

grouped pigmentation (bear tracks),

retinocytoma (retinoma), 740–741, 745

Schnyder’s corneal crystalline dystrophy, 298

397, 691, 692

retinopathy of prematurity (ROP), 642,

schwannoma see neurilemmoma

hypertrophy, 686, 689–692

748–751

Schwartz’s syndrome, 467

melanotic tumors, 685–686, 689–692

retinoschisis

sclera, 314–319

Menkes’ kinky-hair disease, 52

degenerative, 420–422

choroidal melanoma invasion, 716, 717,

diabetes mellitus, 602

juvenile, 437–440, 757

718

drusen, 425, 426, 427, 430, 521

macular, 612

congenital anomalies, 314–315

exudative macular degeneration secondary

retrobulbar neuritis, 513, 619

glaucoma, 657

to focal choroiditis, 434

retrocorneal fibrous membrane, 130–131

inflammation, 96–97, 315–317, 318, 466

idiopathic serous detachment, 423, 424,

retrolental fibroplasia see retinopathy of

lesions simulating conjunctival melanotic

430

prematurity (ROP)

tumors, 684, 685

inflammation, 416, 418

rhabdoid tumor, malignant, 555

rupture caused by contusion, 146–147,

intraocular sequelae, 63, 70

rhabdomyoma, 555

148

iron deposition, 24, 150

rhabdomyosarcoma, 249, 350, 555–557,

senile plaques, 25

melanocytes, 668

563–564, 698

surgical trauma, 125

melanotic tumors, 685–686, 688–693

rhegmatogenous neural retinal detachment,

tumors, 317–319

neural retinal detachment, 462, 467,

61, 462–466

see also corneosclera

468–469

rheumatoid arthritis

scleritis, 96–97, 315–317, 318

nonsurgical trauma, 144–145, 150

scleromalacia perforans, 317

neural retinal detachment, 466

normal anatomy, 395

uveitis, 67

scleritis-associated peripheral keratopathy,

oxalosis, 456–457

rhinoscleroma, 85

270

patterned dystrophies, 448

rhinosporidiosis, 86

sclerocornea, 264

peripheral retinal albinotic spots, 423

Rhizopus, 86

scleroderma, 183–184

pigment epithelial dystrophy, 448

Richter’s syndrome, 574

scleromalacia perforans, 317

sea-fan anomaly, 413, 414

see also skin, pseudoneoplasms and

conjunctiva, 245–248, 314, 355

sebaceous cysts, 189

neoplasms, pigment tumors

corneal involvement, 314

sebaceous glands

normal anatomy, 165, 166

eyelid, 192, 194, 199–201

chalazia, 174–176

pseudoneoplasms and neoplasms, 191–209

incidence, 244

tumors of or resembling, 201–202

benign cystic lesions, 188–189,

Ki-67 labeling index, 244–245

carcinoma, 22, 202, 203, 235, 244–245

190–191

lacrimal drainage system, 211

congenital hyperplasia, 201–202, 265

benign tumors of surface epithelium,

squamous papilloma, conjunctival, 242–243

seborrheic blepharitis, 174

190–196

staining patterns

seborrheic keratosis, 192–193

cancerous tumors of surface

inflammation, 14–15

seclusio pupillae, 68, 69

epithelium, 197–201

pigmentation, 24, 25

senile atrophic macular degeneration see

malacoplakia, 209

staphylococcal infection, orbit, 532

age-related macular

Merkel cell carcinoma, 208–209

staphylococcal scalded-skin syndrome, 181

degeneration (ARMD), dry

mesenchymal tumors, 209

staphyloma, limbal, 632

senile cataract, 380

metastatic tumors, 209

Stargardt’s disease, 440–441

senile disciform macular degeneration see

pigment tumors, 667–676

steatocystoma, 189

age-related macular

precancerous tumors of surface

Steinert’s disease see myotonic dystrophy

degeneration (ARMD, wet

epithelium, 196–197

Stein’s syndrome, 314

senile keratosis, 196–197

tumors of adnexal skin structures,

stem cells

senile retinoschisis, 422

201–208

corneal, 134, 255–256

senile sebaceous gland hyperplasia, 201

sarcoidosis, 93, 94

idiopathic deficiency, 223

senile sebaceous nevi, 201

systemic dermatoses/disease, 171–172,

steroid-induced glaucoma, 652

Senioz’s syndrome, 447

178–188, 239, 343–344

Stevens–Johnson syndrome, 181

sensory retina see retina (neural)

terminology, 166–168

Stickler’s syndrome, 439, 440

serous choroidopathy, idiopathic central, 424

Sly syndrome, 300

Stocker–Holt dystrophy, 286, 287

serous detachment of the RPE, idiopathic,

smallpox, 176–177

Stocker line, 310

423, 424, 430

Smith–Magenis syndrome, 40

strands, acquired vitreous, 484

serpent worm, 92

snowflake cataract, 599

strawberry hemangioma, 544, 545

serpiginous choroiditis, 347–348

snowflake vitreoretinal degeneration (SVD),

streptococcal cellulitis, 174

serpiginous ulcer, chronic, 284–285

440

streptococcal gangrene, 57

Sézary’s syndrome, 580–581

sodium hyaluronate, artificial tears, 112

streptothrix, 84, 85, 210, 211

Shabbir syndrome, 225

Soemmerring’s ring cataract, 117, 118, 380

striate keratopathy, 111

shaken-baby syndrome, 154

solar keratosis, 196–197

stromal desmoplastic reaction, 197, 198

shingles see herpes zoster

solitary fibrous tumor, 553–554

stromal layer of cornea

SHORT syndrome, 263

solitary spindle-cell xanthogranuloma

degenerations, 275, 276–285

sickle-cell disease, 225–226, 412–415, 486,

(SCXG), 343

dystrophies, 238, 285, 290–305, 452

493

Sorsby fundus dystrophy, 450

ingrowth after intraocular surgery, 120

siderosis bulbi, 24, 148, 149, 150

spheroidal degeneration, 279–282

keratitis (interstitial), 267–269

siderosis lenti, 148, 149, 381, 383

spherophakia, 387

normal anatomy, 256, 257

Siegrist’s spots, 410

sphingolipidoses, 451–452, 454

overgrowth after corneal surgery, 130–131

silicone oil, 125, 126–127

spider dystrophy, 448

stromal neoplasms, conjunctival, 248–249

silver

spindle cells

Sturge–Weber syndrome (SWS), 30–31

argyrosis, 188, 235, 236, 684

ciliary body and choroid malignant

styes (external hordeola), 174

as intraocular foreign body, 147

melanoma, 708–709, 710, 711,

subacute necrotizing encephalomyelopathy, 50

Silver–Russell syndrome, 631

712

subacute sclerosing panencephalitis (SSPE),

sinus histiocytosis, 570

iris malignant melanoma, 694–696

64–65

Sipple syndrome, 34

spindle-cell carcinoma, 247

subcutaneous pseudosarcomatous fibromatosis

Sjögren dystrophia reticularis laminae

spindle-cell nevus, 679

see nodular fasciitis

pigmentosae retinae, 448

spindle-cell xanthogranuloma, solitary, 343

subepithelial dystrophies

Sjögren’s syndrome, 223, 236, 275, 533, 535

Spitz nevus, 679

cornea, 285, 289–290

Sjögren–Larsson syndrome, 450

Splendore–Hoeppli phenomenon, 91

see also Reis–Bücklers corneal dystrophy

skin, 165–209

splinter hemorrhages, 610, 612

subepithelial mucinous corneal dystrophy

aging changes, 172–173

spondyloepiphyseal dysplasia congenita,

(SMCD), 289–290

congenital anomalies, 30, 31, 33–34,

439

subepithelial nevus, conjunctiva, 678, 679

168–172, 188

spongiform scleropathy, melanoma-associated,

subhyaloid hemorrhage, 493–494

conjunctival manifestations of disease,

720–721

subneural retinal neovascularization (CNV),

236

spongiosis, 167, 174

432

cysts, 188–191

sporotrichosis, 87

subretinal hemorrhage, after intraocular

inflammation, 173–178, 188

spring catarrh see vernal keratoconjunctivitis

surgery, 112–113

dystrophy (Reis–Bücklers

artificial tears, 112

transitional cell carcinoma, 212

corneal dystrophy), 290, 291,

conjunctival homeostasis, 223–224

transplantation

292–293, 295, 296

keratitis sicca, 274–275

bone marrow transplant retinopathy, 436

superior limbic keratoconjunctivitis (SLK),

Sjögren’s syndrome, 223, 224, 236, 275,

graft-versus-host disease (GvHD)

266–267

533

conjunctivitis, 234

suppurative nongranulomatous inflammation,

tear flow blockage, dacryocystitis, 210–211

penetrating keratoplasty, complications,

57, 59–61, 532

tear gas (chloroacetophenone), 151

129–131

surgical complications

tear secretion, congenital alacrima, 532

terminology, 22

corneal surgery, 129–133, 152

telangiectasia

transudation, meaning, 5

glaucoma surgery, 133

ataxia-telangiectasia, 36

transverse keratotomy, 131

intraocular surgery, 105–123

Coats’ disease, 752, 753

trauma

neural retinal detachment surgery,

hereditary hemorrhagic, 225

nonaccidental, 154

123–129

Leber’s miliary aneurysms, 753

nonsurgical, 105, 134–156

vitreous surgery, 129

orbit, 545

burns, 152–153

sweat gland carcinoma with syringomatous

retinal, 752, 753–754

chemical injuries, 149–152

features, 206

temporal arteritis, 507–509, 513

contusion, 134–145, 146–147

sweat glands

teratoid medulloepithelioma, 687, 688

e ects of non-ocular injuries, 153–154

hidrocystoma, 189, 191

teratoma, orbit, 542, 543

intraocular foreign bodies, 147–149,

tumors of or resembling, 205–208

Terrien’s ulcer, 278–279

311, 381, 383, 535

symmetric marginal dystrophy, 278–279

Terson’s syndrome, 493–494

orbit, 534–535

sympathetic uveitis (sympathetic ophthalmia;

thalidomide, 45

penetrating injuries, 145–147, 148,

sympathetic ophthalmitis), 14,

thermal injuries, 152

534–535

73–75, 98, 129

thermal stromal coagulation, 131

perforating injuries, 145–147, 148

synchysis scintillans (cholesterolosis), 142,

Thiel–Behnke dystrophy, 290, 291, 292–293,

posttraumatic granulomatous

143, 487, 753

295

inflammation, 73–76

synophthalmos, 38, 45, 47

Thomsen’s disease, 538

radiation injuries, 152, 155–156, 368

syphilis, 82–83

thrombocytopenia, 412

surgical see surgical complications

stromal keratitis, 267–268

Thygeson’s superficial punctate keratitis, 266

wound rupture after intraocular surgery,

syringocystadenoma papilliferum (papillary

thyroid disease, 536, 537

122

syringadenoma), 201, 206

tissue and cellular reactions, 22–25

Treacher Collins–Franceschetti syndrome,

syringoid eccrine carcinoma, 206

tissue polarity, 168

265

syringoma, 205–206

Tolosa–Hunt syndrome, 533

trematodes (flukes), 92–93

syringomatous carcinoma, 206

TORCH syndrome, 62–63

Treponema pallidum, 82, 83

systemic lupus erythematosus, 183, 403

torulosis, 85–86

TRIC agent, 231

touch syndrome, corneal, 113, 483

trichilemmal carcinoma, 205

Touton giant cells, 12, 13, 14

trichilemmal cysts, 189

T lymphocytes

juvenile xanthogranuloma, 14, 344

trichilemmoma, 204–205

chronic inflammation, 9–10, 12

toxic anterior segment syndrome (TASS),

trichinosis, 91

herpes stromal keratitis, 267

113–114

trichoadenoma, 203

immunobiology, 15–18, 19

toxic causes

trichoblastoma, 202

immunologic conjunctivitis, 234, 235

cataracts, 381, 383

trichoepithelioma, 202–203, 204

ocular cicatricial pemphigoid, 229,

glaucoma, 652

trichofolliculoma, 203

230

toxic dermatitis, 182

trichomegaly, 170

trachoma, 232

toxic diseases, optic neuritis secondary to,

trilateral retinoblastoma, 734, 746

vernal keratoconjunctivitis, 233–234

511, 513

triploidy, 39–40

see also T-cell lymphoma

toxic endothelial destruction syndrome

trisomy 8 (47,8+), 43

T-cell lymphoma, 184–185

(TEDS), 113, 114

trisomy 13 (47,13+; Patau’s syndrome),

conjunctiva, 248–249

toxic epidermal necrolysis, 181–182, 230–231

38–39, 45

immunophenotyping, 21

toxic retinal degenerations, 434–436

trisomy 18 (47,18+; Edward’s syndrome), 39

intraocular, 355

Toxocara canis, 90, 91, 751, 757

trisomy 21 (47,21+; Down’s syndrome;

orbit, 576, 580–581

toxocariasis, 90–91, 751

mongolism), 39

taches de bougie, sarcoidosis, 95

toxoplasmosis, 88–89

Tropheryma whippelii, 485

Takayasu’s disease, 402–403

trabecular carcinoma, 208–209

tuberculoid leprosy, 81–82

talc emboli, 153, 402

trabecular meshwork, glaucoma, 626–627,

tuberculosis, 79–81

tapeworms (Cestoidea), 92

634, 637, 638, 652

tuberous sclerosis, 34–36, 201

tarsal conjunctiva, 224

trabeculectomy, complications, 133

tularemia, 85, 86

tattooing, corneal, 311, 312

trabeculotomy, complications, 133

tumor necrosis factor, 3

Tay–Sachs disease, 451–452, 453

trachoma, 231–232

tunica vasculosa lentis, persistent, 334

vitreous wick syndrome, 109

Walker–Warburg syndrome, 48–49, 261

xanthogranuloma, 14, 186, 314, 343–344, 568

Wagner-like vitreoretinal degenerations,

warts (verrucas), 176, 178

xanthoma, orbit, 551–552

439

warty dyskeratoma, 194

xanthomatosis of the orbit, 534

vitreous bands, neural retinal detachment,

wasp stings, 145

xeroderma pigmentosum, 172

466, 468

Weber–Christian disease, 188

xerophthalmia, 276

vitreous veils (juvenile retinoschisis), 437–440,

Wegener’s granulomatosis, 184, 210, 234, 318

xerosis (dry eye), 210, 223, 224, 236, 237

757

Weill–Marchesani syndrome, 387–388

vitreous wick syndrome, 109

Weill–Marchesani-like habitus, 439

Vogt’s vertical lines, 304

Werner’s syndrome

yellow mutant-type albinism, 394–395

Vogt–Koyanagi–Harada (VKH) syndrome,

metastatic calcification, 24

74, 97–98

posterior subcapsular cataract, 373

von Arlt’s line, 231, 232

wet ARMD, 426, 427, 430–432

ZAP-70 lymphocytes, 16

von Gierke’s disease, 455

Whipple’s disease, 484–486

Zeis sebaceous glands, 174–176

von Hippel, internal ulcer of, 262

Williams syndrome, 52

Zellweger’s syndrome, 447

von Hippel’s disease (VHL), 29–30

Wilms’ tumor, 49, 50

zinc foreign bodies, 147–148, 149

von Hippel–Lindau disease, 29, 757

Wilson’s disease, 310, 311

Zollinger–Ellison syndrome, 34

von Recklinghausen’s disease (NF type-1),

Wiskott–Aldrich syndrome (WAS), 176

zonal granulomatous inflammation, 13, 14

31–34, 314

Wolf–Hirschhorn (Wolf ’s) syndrome, 40, 261

zonular dialysis, 106

vortex vein invasion, choroidal melanoma,

Wolman’s disease, 452–453

zygomycosis (mucormycosis; phycomycosis),

716, 718

wood splinters, 150

86

Vossius’ ring, 139–140

wounds see trauma

orbital inflammation, 532, 534

W

Wyburn-Mason syndrome, 36

X

Waardenburg’s syndrome, 679

Wagner’s vitreoretinal dystrophy,

X-linked lymphoproliferative syndrome

439–450

(XLP), 64