Ординатура / Офтальмология / Английские материалы / Ocular Oncology_Albert, Polans_2003

Index

[Transpupillary thermotherapy] uveal melanoma, 9–10, 322

Treatment of retinoblastoma, 353–378 Trilateral retinoblastoma, 25

extraocular retinoblastoma, 496–497 Tumorigenesis, genes involved in, 71–75

chromosome 1, 74 chromosome 3, 71–72 chromosome 6, 73–74 chromosome 8, 72–73

Tumor resection techniques, uveal melanoma, 322

Tygerberg, South Africa, treatment of retinoblastoma, 354

Tyrosine kinase system, uveal melanocytes, 198

Ultrasonography, in diagnosis of retinoblastoma, 28–29 Unsuspected retinoblastoma, 447 Uveal melanoma, 1–18, 64–71, 85 biochemical pathways, uveal melanocytes, 189–210

clinical genetics, 2 clinical trials, 379–402 demographics, 1–2 diagnosis, 2–5

clinical features, 2–4 diagnostic modalities, 4–5

epidemiology, 1–2 risk factors

occupational exposure, 40 reproductive factors, 39

epidemiology of, 35–45 future developments, 11–12 gene expression, 81–102 genetics of, 63–79

immunology of, 231–254, 255–268 models of, 269–298

other chromosome changes, 68–69 pathology of, 409–428

prognosis, 10–11

structural alterations, 81–102 survival, 10–11

therapy, 321–352 treatments, 5–10 enucleation, 6

local resection, 8–9 observation, 5–6 radiotherapy, 6–8

transpupillary thermotherapy, 9–10

509

Vascular endothelial growth factor, uveal melanocytes interaction, 204

Vitamin D analogues, 299–320 athymic xenograft model

1alpha-OH-D2 in, effectiveness, toxicity of, 307

16,23-D3 in, effectiveness, toxicity of,

307

effectiveness, toxicity of ergocalciferol in, 303–304

effectiveness of toxicity, calcitriol treatment in, 304

calcitriol, LHbeta-tag, effectiveness, toxicity of, 304–307

characterization of mechanism of arrest of tumor growth, 312–314

experimental procedures, 300–302 analysis of tumor cells death, 301–

302 immunohistochemistry, 302

reverse transcription PCR of VDR cDNA, 300

xenograft and transgenic models, 301 LHbeta-tag transgenic model

1alpha-OH-D2, effectiveness, toxicity of, 307–312

16,23-D3DD, effectiveness, toxicity of,

307

mouse models, genetically engineered, retinoblastoma, transgenic mouse models of retinoblastoma, 483–484

PCR amplification

VDR cDNA from human RB samples, 302–303

VDR cDNA from mouse model of retinoblastoma, 303

in vitro effects of calcitriol, 303 reverse transcription PCR of VDR

cDNA, 300

Y-79 RB cells, presence of vitamin D receptors in, 302

Xenograft and transgenic models, vitamin D analogues, 301

Y-79 RB cells, presence of vitamin D receptors in, vitamin D analogues, 302

Zhengzhou, China, treatment of retinoblastoma, 354