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Ocular Infection

Ocular Infection

Second Edition

David Seal

Applied Vision Research Centre, City University, London, England, UK

Uwe Pleyer

Charité, Humboldt University, Berlin, Germany

With Contributions from

Gregory Booton

The Ohio State University, Columbus, Ohio, USA

Consuelo Ferrer

Instituto Oftalmológico de Alicante, Alicante, Spain

Susanne Gardner

Atlanta, Georgia, USA

Regis Kowalski

University of Pittsburgh, Pittsburgh, Pennsylvania, USA

Philip Thomas

Joseph Eye Hospital, Tiruchirrapalli, Tamil Nadu, India

Informa Healthcare USA, Inc.

52 Vanderbilt Avenue

New York, NY 10017

2007 by Informa Healthcare USA, Inc. Informa Healthcare is an Informa business

No claim to original U.S. Government works

Printed in the United States of America on acid-free paper 10 9 8 7 6 5 4 3 2 1

International Standard Book Number-10: 0-8493-9093-1 (hb : alk. paper)

International Standard Book Number-13: 978-0-8493-9093-7 (hb : alk. paper)

This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequence of their use.

No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers.

For permission to photocopy or use material electronically from this work, please access www. copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC) 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged.

Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe.

Library of Congress Cataloging-in-Publication Data

Seal, David

 

Ocular infection / by David Seal, Uwe Pleyer. – 2nd ed.

 

p. ; cm.

 

Includes bibliographical references and index.

 

ISBN-13: 978-0-8493-9093-7 (hb : alk. paper)

 

ISBN-10: 0-8493-9093-1 (hb : alk. paper)

 

1. Eye–Infections. I. Pleyer, Uwe, 1957-II. Title.

 

[DNLM: 1. Eye Infections–diagnosis. 2. Eye Infections–pathology.

 

3. Eye Infections–therapy. WW 160 S438o 2007]

 

RE96.S43 2007

 

617.7–dc22

2007028097

Visit the Informa web site at

www.informa.com

and the Informa Healthcare Web site at www.informahealthcare.com

Preface to the Second Edition

Many changes have taken place in ophthalmic practice over the last 10 years, and these are reflected in this completely revised and expanded second edition. Likewise, there has been a change in the primary authorship of the book, with Professor Uwe Pleyer taking over for Anthony Bron and John Hay. In this edition, we have rearranged the chapters and expanded the basic science but still kept the book to a reasonable length. We have supplemented the clinical text with numerous flow diagrams, which we hope will please those readers who wish to have “one page” summaries for quick reference. However, the book also retains in-depth discussions of key topics related to the science, diagnosis, and treatment of ocular infection, for the benefit of those who wish to study the subject in more detail.

David Seal

Uwe Pleyer

London and Berlin

iii

Preface to the First Edition

This book has been written to further the understanding of infective eye disease. We have reviewed the literature extensively in an effort to offer a solid foundation for the diagnosis and management of ocular infection. To this end tables have been constructed to highlight important practical points. We hope that this book will prove useful to ophthalmologists, optometrists, microbiologists, and hospital pharmacists concerned with good practice in medicine and the treatment of ocular infection. Our aim is the avoidance of unnecessary blindness due to lack of understanding of the disease process and its chemotherapy.

We are very grateful to all our colleagues, both in the U.K. and overseas, for their advice and assistance with this book, and we especially thank Professor Harold Lambert for his encouragement. In particular, we would like to thank the following, including colleagues in the Tennent Institute, who have supplied clinical and laboratory photographs: Thomas Byers, John Dart, Gordon Dutton, Linda Ficker, Colin Kirkness, Barbara Leppard, Susan Lightman, Ian Mackie, Ron Marsh, Keith Rodgers, Elizabeth Wright, and Peter Wright. We are also particularly grateful to John McCormick for clinical and laboratory photography in the Tennent Institute and to Dorothy Aitken and Sam Cameron for technical electron microscopy.

David Seal

Anthony J. Bron

John Hay

Glasgow and Oxford

v

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