Ординатура / Офтальмология / Английские материалы / Ocular Disease Mechanisms and Management_Levin, Albert_2010
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Commissioning Editor: Russell Gabbedy
Development Editor: Ben Davie
Editorial Assistant: Kirsten Lowson
Project Manager: Srikumar Narayanan
Design: Charles Gray
Illustration Manager: Bruce Hogarth
Marketing Managers (UK/USA): Richard Jones / Radha Mawrie
Ocular Disease: Mechanisms
and Management
Leonard A. Levin, md, phd |
Daniel M. Albert, md, ms |
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Canada Research Chair of Ophthalmology and Visual Sciences |
RRF Emmett A. Humble Distinguished Director of |
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University of Montreal |
the UW Eye Research Institute |
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Montreal, Quebec, Canada |
F.A. Davis Professor, Department of Ophthalmology |
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Professor of Ophthalmology and Visual Sciences |
and Visual Sciences |
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University of Wisconsin |
School of Medicine and Public Health |
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Madison, WI, USA |
University of Wisconsin-Madison |
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University of Wisconsin |
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Madison, WI, USA |
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SAUNDERS an imprint of Elsevier Inc
© 2010, Elsevier Inc All rights reserved.
The chapter entitled 44. Optic Atrophy is in the public domain.
First published 2010
The right of Leonard A. Levin and Daniel M. Albert to be identified as authors of this work has been asserted by them in accordance with the Copyright, Designs and Patents Act 1988.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier’s Rights Department: phone: (+1) 215 239 3804 (US) or (+44) 1865 843830 (UK); fax: (+44) 1865 853333; e-mail: healthpermissions@elsevier.com. You may also complete your request on-line via the Elsevier website at http://www.elsevier.com/permissions.
13 digit ISBN: 978-0-7020-2983-7
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
Library of Congress Cataloging in Publication Data
A catalog record for this book is available from the Library of Congress
Notice
Medical knowledge is constantly changing. Standard safety precautions must be followed, but as new research and clinical experience broaden our knowledge, changes in treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current product information provided by the manufacturer of each drug to be administered to verify the recommended dose, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on experience and knowledge of the patient, to determine dosages and the best treatment for each individual patient. Neither the Publisher nor the author assume any liability for any injury and/or damage to persons or property arising from this publication.
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List of Contributors
Anthony P Adamis MD |
Sally S Atherton PhD |
Audrey M Bernstein PhD |
Adjunct Professor |
Regents Professor and Chair |
Assistant Professor of Ophthalmology |
Division of Ophthalmology and |
Department of Cellular Biology |
Department of Ophthalmology |
Visual Sciences |
and Anatomy |
Mount Sinai School of Medicine |
University of Illinois College of Medicine |
Medical College of Georgia |
New York, NY, USA |
Bronxville, NY, USA |
Augusta, GA, USA |
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Pooja Bhat MD |
Grazyna Adamus PhD |
Tin Aung MBBS MMed(Ophth) |
Fellow |
Professor of Ophthalmology and |
FRCS(Ed) FRCOphth |
Massachusetts Eye Research & |
Graduate Neuroscience |
Senior Consultant and Head |
Surgery Institute |
Ocular Immunology Laboratory |
Glaucoma Service |
Cambridge, MA, USA |
Casey Eye Institute |
Singapore National Eye Centre, |
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Department of Ophthalmology |
Deputy Director, Singapore Eye |
Douglas Borchman PhD |
Oregon Health and Science University |
Research Institute, |
Professor |
Portland, OR, USA |
Associate Professor |
Department of Ophthalmology and |
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National University of Singapore |
Visual Sciences |
Daniel M Albert MD MS |
Singapore |
Kentucky Lions Eye Center |
Emmett A Humble Distinguished Director |
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University of Louisville |
Eye Research Institute, |
Rebecca S Bahn MD |
Louisville, KY, USA |
Professor and Chair Emeritus, |
Professor of Medicine |
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F A Davis Professor, |
Division of Endocrinology |
Stephen Brocchini |
Lorenz E Zimmerman Professor |
Mayo Clinic |
Professor of Chemical Pharmaceutics |
Ophthalmology & Visual Sciences |
Rochester, MN, USA |
Department of Pharmaceutics |
School of Medicine and Public Health |
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The School of Pharmacy |
Clinical Sciences Center |
David Sander Bardenstein MD |
University of London |
University of Wisconsin |
Professor |
London, UK |
Madison, WI, USA |
Departments of Ophthamology and Visual |
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Sciences, and Pathology |
Claude Burgoyne MD |
Ann-Christin Albertsmeyer Can Med |
Case Western Reserve University School |
Research Director |
Research Assistant (Predoctoral) |
of Medicine |
Optic Nerve Head Research Laboratory |
Department of Ophthalmology |
Cleveland, OH, USA |
Devers Eye Institute |
Schepens Eye Research Institute |
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Portland, OR, USA |
Boston, MA, USA |
Neal P Barney MD |
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Associate Professor of Ophthalmology |
Michelle Trager Cabrera MD |
Nishani Amerasinghe BSc MBBS MRCOphth |
Department of Ophthalmology and |
Clinical Associate |
Specialist Registrar |
Visual Sciences |
Department of Opthalmology |
Southampton Eye Unit |
University of Wisconsin School of Medicine |
Duke University |
Southampton University Hospitals |
Madison, WI, USA |
Durham, NC, USA |
NHS Trust |
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Southampton, UK |
David C Beebe PhD FARVO |
Richard J Cenedella |
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The Janet and Bernard Becker Professor of |
Professor |
Michael G Anderson PhD |
Ophthalmology and Visual Sciences, |
Department of Biochemistry |
Assistant Professor of Molecular Physiology |
Professor of Cell Biology and Physiology |
A T Still University of Health Sciences, |
and Biophysics |
Department of Ophthalmology and |
Kirksville College of Osteopathic Medicine |
Department of Molecular Physiology |
Visual Sciences |
Kirksville, MO, USA |
and Biophysics |
Washington University |
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University of Iowa |
St Louis, MO, USA |
Jin-Hong Chang PhD |
Iowa City, IA, USA |
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Assistant Professor of Ophthalmology |
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Adrienne Berman MD |
Department of Opthalmology and |
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Clinical Assistant Professor |
Visual Sciences |
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Department of Ophthalmology and |
University of Illinois at Chicago |
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Visual Sciences |
Chicago, IL, USA |
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University of Illinois Eye and Ear Infirmary |
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Chicago, IL, USA |
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List of Contributors
|
Aimee Chappelow MD |
Annegret Hella Dahlmann-Noor |
Joseph L Demer MD PhD |
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Cole Eye Institute |
Dr med PhD FRCOphth FRCS(Ed) DipMedEd |
The Leonard Apt Professor of |
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The Cleveland Clinic Foundation |
Senior Clinical Research Associate |
Ophthalmology, |
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Cleveland, OH, USA |
Ocular Biology and Therapeutics |
Professor of Neurology |
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UCL Institute of Ophthalmology |
Jules Stein Eye Institute |
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Anuj Chauhan PhD |
London, UK |
David Geffen School of Medicine |
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Associate Professor and Director of |
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University of California, Los Angeles |
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the Graduate Programs |
Reza Dana MD MPH MSc |
Los Angeles, CA, USA |
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Department of Chemical Engineering |
Professor and Director of Cornea Service |
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University of Florida |
Massachusetts Eye & Ear Infirmary |
Suzanne M Dintzis MD PhD |
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Gainesville, FL, USA |
Harvard Medical School |
Assistant Professor |
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Boston, MA, USA |
Department of Pathology |
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Abbot F Clark PhD |
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University of Washington School of |
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Professor of Cell Biology and Anatomy |
Helen Danesh-Meyer MBChB FRANZCO |
Medicine |
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and Director |
Sir William & Lady Stevenson Associate |
Seattle, WA, USA |
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North Texas Eye Research Institute |
Professor of Ophthalmology |
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University of North Texas Health |
Department of Ophthalmology |
J Crawford Downs PhD |
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Science Center |
University of Auckland |
Associate Scientist and Research Director |
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Fort Worth, TX, USA |
Auckland, New Zealand |
Ocular Biomechanics Laboratory |
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Devers Eye Institute |
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Ellen B Cook PhD |
Julie T Daniels BSc(Hons) PhD |
Portland, OR, USA |
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Associate Scientist |
Reader in Stem Cell Biology and |
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Department of Medicine |
Transplantation |
Henry Edelhauser PhD |
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University of Wisconsin School of Medicine |
UCL Institute of Ophthalmology |
Ferst Professor and Director of |
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and Public Health |
London, UK |
Ophthalmology Research |
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Madison, WI, USA |
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Department of Ophthalmology |
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Darlene A Dartt PhD |
Emory University Eye Center |
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Zélia M Corrêa MD PhD |
Senior Scientist, Harold F. Johnson |
Atlanta, GA, USA |
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Assistant Professor of Ophthalmology |
Research Scholar |
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Department of Ophthalmology |
Schepens Eye Research Institute, |
David Ellenberg MD |
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University of Cincinnati College |
Associate Professor |
Research Fellow |
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of Medicine |
Harvard Medical School |
Department of Ophthalmology and |
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Cincinnati, OH, USA |
Schepens Eye Research Institute |
Visual Sciences |
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Boston, MA, USA |
University of Illinois at Chicago |
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Scott Cousins MD |
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Chicago, IL, USA |
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The Robert Machemer Professor of |
Mohammad H Dastjerdi MD |
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Ophthalmology and Immunology, |
Postdoctoral Fellow |
Victor Elner MD PhD |
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Vice Chair for Research |
Schepens Eye Research Institute |
The Ravitz Foundation Professor of |
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Department of Ophthalmology |
Boston, MA, USA |
Ophthlamology and Visual Sciences |
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Duke University School of Medicine |
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Professor, Department of Pathology |
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Durham, NC, USA |
Nigel W Daw PhD |
Kellogg Eye Center |
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Professor Emeritus of Ophthalmology and |
University of Michigan |
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Gerald Cox MD PhD FACMG |
Visual Science |
Ann Arbor, MI, USA |
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Staff Physician in Genetics, Children’s |
Departments of Ophthalmology and |
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Hospital Boston |
Visual Science |
Steven K Fisher PhD |
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Instructor of Pediatrics, Harvard |
University of Yale |
Professor, Molecular Cellular and |
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Medical School |
New Haven, CT, USA |
Developmental Biology |
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Vice President of Clinical Research |
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Neuroscience Research Institute |
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Genzyme Corporation |
Daniel G Dawson MD |
University of California, Santa Barbara |
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Cambridge, MA, USA |
Visiting Assistant Professor of |
Santa Barbara, CA, USA |
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Ophthalmology |
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Scott Adam Croes MS PhD |
Emory University Eye Center |
Robert Folberg MD |
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Professor of Human Anatomy |
Atlanta, GA, USA |
Dean, Oakland University William |
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and Physiology |
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Beaumont School of Medicine, |
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Department of Biology |
Alejandra de Alba Campomanes |
Professor of Biomedical Sciences, Pathology, |
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Shasta College |
MD MPH |
and Ophthalmology |
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Redding, CA, USA |
Director of Pediatric Ophthalmology |
Oakland University William Beaumont |
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San Francisco General Hospital |
School of Medicine |
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Karl G Csaky MD PhD |
San Francisco, CA, USA |
Rochester, MI, USA |
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Associate Professor |
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Department of Ophthalmology |
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Duke University |
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Durham, NC, USA |
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List of Contributors |
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C Stephen Foster MD FACS FACR |
Lynn K Gordon MD PhD |
Vinay Gutti MD |
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Founder and President, Ocular Immunology |
Associate Professor Ophthalmology |
Private Practice |
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and Uveitis Foundation, |
Jules Stein Eye Institute |
Cornea, External Disease and |
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Clinical Professor of Ophthalmology |
UCLA School of Medicine |
Refractive Surgery |
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Harvard Medical School, |
Los Angeles, CA, USA |
La Mirada Eye and Laser Center |
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Founder and President |
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La Mirada, CA, USA |
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Massachusetts Eye Research and |
Irene Gottlob MD |
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Surgery Institution |
Professor of Ophthalmology |
John R Guy MD |
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Cambridge, MA, USA |
Department of Cardiovascular Sciences |
Bascom Palmer Eye Institute |
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Ophthalmology Group |
Miami, FL, USA |
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Gary N Foulks MD FACS |
University of Leicester |
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The Arthur and Virginia Keeney Professor |
Leicester Royal Infirmary |
J William Harbour MD |
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of Ophthalmology and Vision Science |
Leicester, UK |
The Paul A Cibis Distinguished Professor |
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Division of Ophthalmology |
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of Ophthalmology |
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University of Louisville School of Medicine |
John D Gottsch MD |
Department of Ophthalmology and |
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Louisville, KY, USA |
The Margaret C Mosher Professor of |
Visual Sciences |
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Ophthalmology |
Washington University School of Medicine |
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Frederick T Fraunfelder MD |
Johns Hopkins School of Medicine |
St Louis, MO, USA |
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Professor of Ophthalmology |
Wilmer Eye Institute |
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Casey Eye Institute |
Baltimore, MD, USA |
Mary Elizabeth Hartnett MD |
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Portland, OR, USA |
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Professor of Ophthalmology |
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Frank M Graziano MD PhD |
Department of Ophthalmology |
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Frederick W Fraunfelder MD |
Professor of Medicine |
University of North Carolina |
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Associate Professor of Ophthalmology |
Department of Medicine |
Chapel Hill, NC, USA |
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Casey Eye Institute |
University of Wisconsin School of Medicine |
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Portland, OR, USA |
and Public Health |
Sohan S Hayreh MD MS PhD DSc FRCS(Edin) |
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Madison, WI, USA |
FRCS(Eng) FRCOphth(Hon) |
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Anne Fulton MD |
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Professor Emeritus of Ophthalmology |
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Senior Associate in Ophthalmology |
Hans E Grossniklaus MD MBA |
Department of Ophthalmology & Director |
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Department of Ophthalmology |
Professor of Medicine |
Ocular Vascular Clinic |
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Children’s Hospital Boston |
Emory Eye Center |
University of Iowa Hospitals and Clinics |
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Boston, MA, USA |
Emory University School of Medicine |
Iowa City, IA, USA |
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Atlanta, GA, USA |
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Ronald Gaster MD |
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Susan Heimer PhD |
|
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Professor of Ophthalmology |
Deborah Grzybowski PhD |
Postdoctoral Research Fellow |
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Department of Opthalmology |
Professor of Ophthalmology and |
Schepens Eye Research Institute and |
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University of California |
Biomedical Engineering |
Department of Ophthalmology |
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Irvine, CA, USA |
The Ohio State University |
Harvard Medical School |
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College of Medicine |
Boston, MA, USA |
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Stylianos Georgoulas MD |
Columbus, OH, USA |
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Ocular Repair and Regeneration |
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Robert Hess DSc |
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Biology Unit |
Clyde Guidry PhD |
Professor and Director of Research |
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UCL Institute of Ophthalmology |
Associate Professor of Ophthalmology |
Department of Ophthalmology |
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London, UK |
Department of Ophthalmology |
McGill University |
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University of Alabama School of Medicine |
Montreal, QC, Canada |
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Michael S Gilmore PhD |
Birmingham, AB, USA |
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The C L Schepens Professor of |
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Nancy M Holekamp MD |
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Ophthalmology |
Neeru Gupta MD PhD FRCSC DABO |
Partner, Barnes Retina Institute, |
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Harvard Medical School, |
Professor of Ophthalmology and Vision |
Professor of Clinical Ophthalmology |
|
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Senior Scientist |
Sciences, Laboratory Medicine and |
Department of Ophthalmology and |
|
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Schepens Eye Research Institute |
Pathobiology, University of Toronto, |
Visual Sciences |
|
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Boston, MA, USA |
Director |
Washington University School of Medicine |
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Glaucoma & Nerve Protection Unit |
St Louis, MO, USA |
|
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Ilene K Gipson PhD |
Keenan Research Centre at the Li Ka Shing |
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Senior Scientist and Professor of |
Knowledge Institute |
Suber S Huang MD MBA |
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Ophthalmology |
St Michael’s Hospital |
The Philip F. and Elizabeth G. Searle |
|
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Department of Ophthalmology |
Toronto, ON, Canada |
Professor of Ophthalmology, |
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Schepens Eye Research Institute |
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Vice-Chair, Department of Ophthalmology |
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Boston, MA, USA |
David H Gutmann MD PhD |
& Visual Sciences |
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The Donald O Schnuck Family Professor |
Case Western Reserve University School |
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Michaël J A Girard PhD |
Department of Neurology, |
of Medicine, |
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Ocular Biomechanics Laboratory |
Director, Neurofibromatosis Center |
Director, Center for Retina and |
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Devers Eye Institute, Legacy Health System |
Washington University School of Medicine |
Macular Disease |
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Portland, OR, USA |
St Louis, MO, USA |
University Hospitals Eye Institute |
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Cleveland, OH, USA |
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List of Contributors
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Sudha K Iyengar PhD |
Peng Tee Khaw PhD FRCP FRCS FRCOphth |
Leonard A Levin MD PhD |
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Professor |
FIBiol FRCPath FMedSci |
Canada Research Chair of Ophthalmology |
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Departments of Epidemiology & Biostatistics |
Professor of Ocular Healing and Glaucoma |
and Visual Sciences |
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and Department of Ophthalmology |
and Consultant Ophthalmic Surgeon, |
Department of Ophthalmology |
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Case Western Reserve University |
Director of Research and Development, |
University of Montreal, |
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Cleveland, OH, USA |
Moorfields Eye Hospital NHS |
Professor, Department of Ophthalmology |
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Foundation Trust, |
and Visual Sciences |
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Allen T Jackson |
Director, National Institute for Health |
University of Wisconsin |
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Massachusetts Eye Research and |
Biomedical Research Centre, |
Madison, WI, USA |
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Surgery Institute |
Programme Director, Eyes & Vision, UCL |
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Harvard Medical School |
Partners Academic Health Science Centre |
Geoffrey P Lewis PhD |
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Cambridge, MA, USA |
London, UK |
Research Biologist, Neurobiology |
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Neuroscience Research Institute |
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L Alan Johnson MD |
Alice S Kim MD |
University of California, Santa Barbara |
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Private Practice |
Division of Ophthalmology |
Santa Barbara, CA, USA |
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Sierra Eye Associates |
Maimonides Medical Center |
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Reno, NV, USA |
Brooklyn, NY, USA |
Zhuqing Li MD PhD |
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Staff Scientist |
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Peter F Kador PhD |
Henry Klassen MD PhD |
Laboratory of Immunology |
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Professor |
Assistant Professor |
National Eye Institute |
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Departments of Ophthalmology and |
Department of Ophthalmology |
National Institutes of Health |
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Pharmaceutical Sciences |
University of California, Irvine, |
Bethesda, MD, USA |
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University of Nebraska Medical Center |
School of Medicine |
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Omaha, NE, USA |
Orange, CA, USA |
Amy Lin MD |
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Assistant Professor of Ophthalmology |
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Alon Kahana MD PhD |
Paul Knepper MD PhD |
Department of Ophthalmology |
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Full Member, University of Michigan |
Research Scientist |
Loyola University |
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Comprehensive Cancer Center, |
University of Illinois at Chicago |
Maywood, IL, USA |
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Attending Surgeon, C S Mott |
Department of Opthalmology & |
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Children’s Hospital, |
Visual Science |
Robert A Linsenmeier PhD |
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Assistant Professor |
Chicago, IL, USA |
Professor of Biomedical Engineering, |
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Department of Ophthalmology and |
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Neurobiology & Physiology, and |
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Visual Sciences |
Jane F Koretz PhD |
Ophthalmology |
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Kellogg Eye Center |
Professor of Biophysics |
Biomedical Engineering Department |
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University of Michigan |
Biochemistry and Biophysics Program |
Northwestern University |
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Ann Arbor, MI, USA |
Rensselaer Polytechnic Institute, |
Evanston, IL, USA |
|
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Science Center |
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Randy Kardon MD PhD |
Troy, NY, USA |
Robert Listernick MD |
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Professor and Director of |
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Professor of Pediatrics, Feinberg School of |
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Neuro-ophthalmology, |
Mirunalini Kumaradas MD Opth(SL) |
Medicine, Northwestern University, |
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Pomerantz Family Chair in Ophthalmology, |
FRCS (UK) |
Attending Physician |
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Director for Iowa City VA Center for |
Lecturer |
Division of General Academic Pediatrics |
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Prevention and Treatment of Vision Loss |
Faculty of Medicine |
Children’s Memorial Hospital |
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Department of Ophthalmology and |
University of Colombo |
Chicago, IL, USA |
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Visual Sciences |
Colombo, Sri Lanka |
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University of Iowa and Department of |
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Martin Lubow MD |
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Veterans Affairs |
Jonathan H Lass MD |
Associate Professor of Ophthalmology |
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Iowa City, IA, USA |
The Charles I Thomas Professor and |
Department of Ophthalmology |
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Chairman |
The Ohio State University Eye and |
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Maria Cristina Kenney MD PhD |
Department of Ophthalmology and |
Ear Institute |
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Professor of Ophthalmology |
Visual Sciences |
Columbus, OH, USA |
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The Gavin Herbert Eye Institute |
Case Western Reserve University, |
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Orange, CA, USA |
Director, University Hospitals Eye Institute |
Andrew Maniotis PhD |
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Cleveland, OH, USA |
Visiting Associate Professor of |
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Timothy Scott Kern PhD |
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Bioengineering |
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Professor of Medicine |
David Lederer MD |
Division of Science and Engineering |
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Department of Medicine |
Fellow |
University of Illinois at Chicago |
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Division of Clinical and Molecular |
Department of Ophthalmology |
Chicago, IL, USA |
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Endocrinology |
Duke University |
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Center for Diabetes Research |
Durham, NC, USA |
Pascale Massin MD PhD |
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Case Western Reserve University |
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Professor of Ophthalmology |
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Cleveland, OH, USA |
Mark Lesk MSc MD FRCS(C) CM DABO |
Ophthalmology Department |
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Director of Vision Health Research |
Lariboisiere Hospital |
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University of Montreal |
Paris, France |
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Montreal, QC, Canada |
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List of Contributors |
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Katie Matatall BS |
Robert Nickells BSc PhD |
Jonathan T Pribila MD, PhD |
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Department of Ophthalmology & |
Professor of Ophthalmology and |
Pediatric Ophthalmology and Adult |
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Visual Sciences |
Visual Sciences |
Strabismus Fellow |
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Washington University School of Medicine |
Department of Ophthalmology and |
Department of Ophthalmology |
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St Louis, MO, USA |
Visual Sciences |
University of Minnesota |
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University of Wisconsin |
Minneapolis, MN, USA |
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Russell L McCally PhD |
Madison, WI, USA |
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Associate Professor of Ophthalmology, |
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Frank A Proudlock PhD |
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The Wilmer Eye Institute, Johns Hopkins |
Robert B Nussenblatt MD MPH |
Lecturer in Ophthalmology |
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Medical Institutions |
Department of Pathology and |
Ophthalmology Group |
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Principal Professional Staff |
Cancer Center |
University of Leicester |
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Applied Physics Laboratory |
University of Illinois |
Robert Kilpatrick Clinical Sciences Building |
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Johns Hopkins University |
Chicago, IL, USA |
Leicester Royal Infirmary |
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Laurel, MD, USA |
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Leicester, UK |
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Joan M O’Brien MD |
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Stephen D McLeod MD |
Professor of Ophthalmology and Pediatrics |
Xiaoping Qi MD |
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Professor of Ophthalmology |
Comprehensive Cancer Center |
Associate Scientist of Ophthalmology |
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Department of Ophthalmology |
University of California San Francisco |
College of Medicine |
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University of California San Francisco |
San Francisco, CA, USA |
University of Florida |
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San Francisco, CA, USA |
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Gainesville, FL, USA |
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Daniel T Organisciak PhD |
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Muhammad Memon MD |
Professor of Biochemistry and |
Narsing A Rao MD |
|
|
Visiting Academic |
Molecular Biology, |
Professor of Ophthalmology and Pathology, |
|
|
Department of Neuroscience |
Director, Petticrew Research Laboratory |
Keck School of Medicine, University of |
|
|
Imperial College London |
Department of Biochemistry and |
Southern California, |
|
|
London, UK |
Molecular Biology |
Director of Experimental Ophthalmic |
|
|
|
Boonshoft School of Medicine |
Pathology and Ocular Inflammations |
|
|
Joan W Miller MD |
Wright State University |
Doheny Eye Institute |
|
|
The Henry Willard Williams Professor of |
Dayton, OH, USA |
Los Angeles, CA, USA |
|
|
Ophthalmology and Chair, Harvard |
|
|
|
|
Medical School, |
Michel Paques MD PhD |
Robert Ritch MD |
|
|
Chief, Department of Ophthalmology |
Professor of Ophthalmology |
Professor of Ophthalmology, New York |
|
|
Massachusetts Eye and Ear Infirmary |
Clinical Investigation Center |
Medical College, Valhalla, NY, |
|
|
Boston, MA, USA |
XV-XX Hospital and University of Paris VI |
The Shelley and Steven Einhorn |
|
|
|
Paris, France |
Distinguished Chair in Ophthalmology, |
|
|
Austin K Mircheff PhD |
|
Chief, Glaucoma Services |
|
|
Professor of Physiology & Biophysics and |
Heather R Pelzel BSc |
Surgeon Director |
|
|
Professor of Ophthalmology |
Research Assistant |
New York Eye and Ear Infirmary |
|
|
Department of Physiology & Biophysics |
Department of Ophthalmology and |
New York, NY, USA |
|
|
Keck School of Medicine |
Visual Sciences |
|
|
|
University of Southern California |
University of Wisconsin |
Joseph F Rizzo III |
|
|
Los Angeles, CA, USA |
Madison, WI, USA |
Associate Professor of Ophthalmology |
|
|
|
|
Massachusetts Eye and Ear Infirmary |
|
|
Jay Neitz PhD |
Shamira Perera MBBS BSc FRCOphth |
Harvard Medical School |
|
|
The Bishop Professor |
Research Fellow, Singapore Eye |
Boston, MA, USA |
|
|
Department of Ophthalmology |
Research Institute, |
|
|
|
University of Washington |
Consultant |
Michael D Roberts PhD |
|
|
Seattle, WA, USA |
Glaucoma Service |
Post Doctoral Research Fellow |
|
|
|
Singapore National Eye Centre |
Ocular Biomechanics Laboratory |
|
|
Maureen Neitz PhD |
Singapore |
Devers Eye Institute |
|
|
The Ray H Hill Professor |
|
Portland, OR, USA |
|
|
Department of Ophthalmology |
Eric A Pierce MD PhD |
|
|
|
University of Washington |
Associate Professor of Ophthalmology |
James T Rosenbaum MD |
|
|
Seattle, WA, USA |
F M Kirby Center for Molecular |
Professor of Ophthalmology, Medicine and |
|
|
|
Ophthalmology |
Cell Biology |
|
|
Christine C Nelson MD FACS |
University of Pennsylvania School of |
The Edward E Rosenbaum Professor of |
|
|
Professor of Ophthalmology and Surgery |
Medicine |
Inflammation Research |
|
|
Kellog Eye Center |
Philadelphia, PA, USA |
Oregon Health & Science University |
|
|
University of Michigan |
|
Portland, OR, USA |
|
|
Ann Arbor, MI, USA |
Jean Pournaras MD |
|
|
|
|
Research Fellow |
Barry Rouse PhD DSc |
|
|
|
Service d’ophtalmologie |
Distinguished Professor |
|
|
|
Hôpital Lariboisière |
Department of Pathobiology |
|
|
|
Paris, France |
University of Tennessee |
|
|
|
|
Knoxville, TN, USA |
|
|
|
|
|
|
|
xiii
List of Contributors
|
Daniel R Saban PhD |
Genevieve Aleta Secker PhD BSc |
Arun N E Sundaram MBBS FRCPC |
|
Postdoctoral Fellow in Ophthalmology |
Post-Doctoral Fellow |
Fellow, Division of Neurology and Vision |
|
Division of Ophthalmology |
SA Pathology |
Sciences Research Program, University of |
|
Schepens Eye Research Institute |
Centre for Cancer Biology |
Toronto, |
|
Boston, MA, USA |
Department of Haematology |
Consultant |
|
|
Adelaide, SA, Australia |
Neuro-ophthalmology Center |
|
Alfredo A Sadun MD PhD |
|
University Health Network |
|
Thornton Professor of Ophthalmology |
Srilakshmi M Sharma MRCP MRCOphth |
Toronto, ON, Canada |
|
and Neurosurgery |
Uveitis Fellow |
|
|
Department of Ophthalmology |
Bristol Eye Hospital |
Janet S Sunness MD |
|
USC Keck School of Medicine |
University of Bristol NHS Trust |
Medical Director |
|
Los Angeles, CA, USA |
Bristol, UK |
Richard E Hoover Rehabilitation Services |
|
|
|
for Low Vision and Blindness |
|
Abbas K Samadi PhD |
James A Sharpe MD FRCPC |
Greater Baltimore Medical Center |
|
Assistant Professor of Surgery and |
Professor of Neurology, Medicine, |
Baltimore, MD, USA |
|
Biochemistry |
Ophthalmology and Visual Sciences, and |
|
|
Department of Biochemistry |
Otolaryngology, University of Toronto, |
Nathan T Tagg MD |
|
University of Kansas Medical Center |
Director |
Neurologist and Neuro-ophthalmologist |
|
Kansas City, KS, USA |
Neuro-ophthalmology Center |
Walter Reed Army Medical Center |
|
|
University Health Network |
National Naval Medical Center |
|
Pranita Sarangi BVSc&AH PhD |
Toronto, ON, Canada |
Bethesda, MD, USA |
|
Postdoctoral Research Associate |
|
|
|
David H Smith Center for Vaccine Biology |
Heather Sheardown BEng PhD |
Daniela Toffoli MD |
|
and Immunology |
Professor |
Ophthalmology Resident, PGY-5 |
|
University of Rochester Medical Center |
Department of Chemical Engineering and |
Department of Ophthalmology |
|
Rochester, NY, USA |
School of Biomedical Engineering |
Université de Montréal |
|
|
McMaster University |
Montréal, QC, Canada |
|
Andrew P Schachat MD |
Hamilton, ON, Canada |
|
|
Professor of Ophthalmology, Lerner College |
|
Cynthia A Toth MD |
|
of Medicine |
Alex Shortt MD PhD MRCOphth |
Professor of Ophthalmology and |
|
Vice Chairman |
Clinical Lecturer in Ophthalmic |
Biomedical Engineering |
|
Cole Eye Institute |
Translational Research |
Department of Biomedical Engineering |
|
Cleveland Clinic Foundation |
Biomedical Research Centre for |
Duke University |
|
Cleveland, OH, USA |
Ophthalmology |
Durham, NC, USA |
|
|
Moorfields Eye Hospital |
|
|
Joel E Schechter PhD |
London, UK |
Elias I Traboulsi MD |
|
Professor of Cell and Neurobiology |
|
Professor of Ophthalmology |
|
Keck School of Medicine |
Ying-Bo Shui MD PhD |
Cleveland Clinic Lerner College of Medicine |
|
University of Southern California |
Senior Scientist |
Case University |
|
Los Angeles, CA, USA |
Department of Ophthalmology and |
The Cole Eye Institute |
|
|
Visual Sciences |
Cleveland, OH, USA |
|
A Reagan Schiefer MD |
Washington University in St Louis |
|
|
Trainee in Endocrinology |
St Louis, MO, USA |
James C Tsai MD |
|
Division of Endocrinology |
|
The Robert R Young Professor and |
|
Mayo Clinic |
Ian Sigal PhD |
Chairman |
|
Rochester, MN, USA |
Research Associate |
Department of Ophthalmology and |
|
|
Devers Eye Institute |
Visual Science |
|
Ursula Schlötzer-Schrehardt ProfDr |
Ocular Biomechanics Laboratory |
Yale University School of Medicine, |
|
Professor |
Portland, OR, USA |
Chief of Ophthalmology, Yale-New |
|
Department of Ophthalmology |
|
Haven Hospital |
|
University of Erlangen-Nürnberg |
James L Stahl PhD |
Yale Eye Center |
|
Erlangen, Germany |
Associate Scientist |
New Haven, CT, USA |
|
|
Department of Medicine |
|
|
Ingo Schmack MD |
University of Wisconsin School of Medicine |
Budd Tucker PhD |
|
Attending Physician |
and Public Health |
Investigator |
|
University of Bochum |
Madison, WI, USA |
Department of Ophthalmology |
|
Department of Ophthalmology |
|
Schepens Eye Research Institute, Harvard |
|
Bochum, Germany |
Roger F Steinert MD |
Medical School |
|
|
Professor and Chair of Ophthalmology, |
Boston, MA, USA |
|
Leopold Schmetterer PhD |
Professor of Biomedical Engineering, |
|
|
Professor |
Director, Gavin Herbert Eye Institute |
|
|
Departments of Clinical Pharmacology and |
University of California Irvine |
|
|
Biomedical Engineering and Physics |
Irvine, CA, USA |
|
|
Medical University of Vienna |
|
|
|
Vienna, Austria |
|
|
|
|
|
|
xiv
