Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:
Ординатура / Офтальмология / Английские материалы / Minimizing Incisions and Maximizing Outcomes in Cataract Surgery_Alio, Fine_2010.pdf
Скачиваний:
0
Добавлен:
28.03.2026
Размер:
17.96 Mб
Скачать

8.3.4 Intraocular Lenses to Restore and Preserve Vision Following Cataract Surgery

261

difference between the two eyes. Of the 30% that could tell a difference, none perceived the difference before I checked and none felt the difference was bothersome. With more than 40,000,000 AcrySof® Natural IOLs implanted worldwide at the time of this writing, the authors are not aware of any confirmed reports of color perception night vision or circadian rhythm problems.

Summary

Clinical experience with blue light filtering IOLs showed no difficulty with color perception or night vision.

8.3.4.6Unresolved Issues and Future Considerations

Laboratory studies have demonstrated the protective benefit provided by filtering blue light for cultured RPE cells. However, the benefits of blue-light filtering IOLs in preventing the development, or worsening of macular degeneration or uveal melanoma have not been proven clinically. A large multicentered prospective clinical study will be necessary to determine if these IOLs truly provide a protective effect. Additionally, there may be a role for different levels of blue light filtering capabilities in these lenses in an effort to maximize retinal protection while minimizing any possible compromise to the quality of vision.

Take Home Pearls

ßNewer technologies provide us the opportunity to improve vision following cataract or RLE

surgery more substantially and predictably than ever before.

ßWe now need to make efforts to maintain that vision long-term.

ßGiven the growing body of evidence, implicating blue light as a potential factor in the wors-

ening of ARMD and the positive collective clinical experience with blue light filtering IOLs, it makes sense to implant these protective IOLs, when possible.

ßBlue light filtering IOLs will eventually become the standard of care in cataract and RLE surgery.

References

1.Alio J, Tavolato M, De la Hoz F, Claramonte P, RodriguezPrats J, Galal A. Near vision restoration with refractive lens exchange and pseudoaccommodating and multifocal refractive and diffractive intraocular lenses: comparative clinical study. J Cataract Refract Surg 2004; 30:2494–2503

2.Stachs O, Schneider H, Stave J, Guthoff R. Potentially accommodating intraocular lenses – an in vitro and in vivo study using three-dimensional high-frequency ultrasound. J Refract Surg 2005; 21:37–45

3.Nuijts R, et al Clinical outcomes and patient satisfaction after cataract surgery with the array and AcrySof ReSTOR multifocal IOLs. In: The ASCRS Annual Meeting, 2005

4.Chang D. Prospective functional and clinical comparison of bilateral ReZoom and ReSTOR intraocular lenses I patients 70 years or younger. J Cataract Refract Surg 2008; 34:934–941

5.Ham W, Mueller A, Sliney DH. Retinal sensitivity to short wavelength light. Nature 1976; 260:153–155

6.Marshall JC, Gordon KD, McCauley CS, de Souza Filho JP, Burnier MN. The effect of blue light exposure and use of intraocular lenses on human uveal melanoma cell lines. Melanoma Res 2006; 16(6):537–541

7.Lerman S. Biologic and chemical effects of ultraviolet radiation. Radiant Energy and the Eye. Macmillan, New York, 1980, pp 132–133

8.Mainster MA. Spectral transmittance of intraocular lenses

and retinal damage from intense light sources. Am J Ophthalmol 1978; 85:167–170

9.Pollack A, et al Age-related macular degeneration after extracapsular cataract extraction with intraocular lens implantation. Ophthalmology 1996; 103:1546–1554

10.Age-Related Eye Disease Study Group. Risk factors associated with age-related macular degeneration. A case-control study in the Age-Related Eye Disease Study: Age-Related Eye Disease Study report number 3. Ophthalmology 2000; 107(12):2224–2232

11.Marshall J. The effects of ultraviolet radiation and blue light on the eye. In Cronly-Dillon J (ed) Susceptible Visual Apparatus (Vision and Visual Dysfunction; vol. 16). Macmillan, London, 1991

12.Marshall J, Mellerio J, Palmer DA. Damage to pigeon retinae by commercial light sources operating at moderate levels. Vision Res 1971; 11(10):1198–1199

13.Sperling HG, Johnson C, Harwerth RS. Differential spectral photic damage to primate cones. Vision Res 1980; 20(12): 1117–1125

14.Sykes SM, Robison WG Jr, Waxler M, Kuwabara T. Damage to the monkey retina by broad-spectrum fluorescent light. Invest Ophthalmol Vis Sci 1981; 20(4):425–434

15.Sparrow JR, Cai B. Blue light-induced apoptosis of A2Econtaining RPE: involvement of caspase-3 and protection by Bcl-2. Invest Ophthalmol Vis Sci 2001; 42(6):1356–1362

16.Ben-Shabat S, Parish CA, Vollmer HR, Itagaki Y, Fishkin N, Nakanishi K, Sparrow JR. Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin. J Biol Chem 2002; 277(9):7183–7190

17.Liu J, Itagaki Y, Ben-Shabat S, Nakanishi K, Sparrow JR. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane. J Biol Chem 2000; 275(38):29354–29360

262

R. J. Cionni and D. Hair

18.Winkler BS, Boulton ME, Gottsch JD, Sternberg P. Oxidative damage and age-related macular degeneration. Mol Vis 1999; 5:32

19.Roberts JE. Ocular phototoxicity. J Photochem Photobiol 2001; 64(2–3):136–143

20.Taylor HR, West S, Munoz B, et al The long-term effects of visible light on the eye. Arch Ophthalmol 1992; 110:99–104

21.Cruickshanks KJ, Klein R, Klein BE, Nondahl DM. Sunlight and the 5-year incidence of early age-related maculopathy: the beaver dam eye study. Arch Ophthalmol 2001; 119:246–250

22.Darzins P, Mitchell P, Heller RF. Sun exposure and agerelated macular degeneration. An Australian case-control study. Ophthalmology 1997; 104:770–776

23.Delcourt C, Carriere I, Ponton-Sanchez A, et al Light exposure and the risk of age related macular degeneration: the Pathologies Oculaires Liees a l’Age (POLA) study. Arch Ophthalmol 2001; 119:1463–1468

24.McCarty CA, Mukesh BN, Fu CL, et al Risk factors for agerelated maculopathy: The Visual Impairment Project. Arch Ophthalmol 2001; 119:1455–1462

25.Mainster MA. Light and macular degeneration: a biophysical and clinical perspective. Eye 1987; 1:304–310

26.Nilsson SE, Textorius O, Andersson BE, Swenson B. Clear PMMA versus yellow intraocular lens material. An electrophysiologic study on pigmented rabbits regarding “the blue light hazard”. Prog Clin Biol Res 1989; 314:539–553

27.Li ZL, Tso MO, Jampol LM, Miller SA, Waxler M. Retinal injury induced by near-ultraviolet radiation in aphakic and pseudophakic monkey eyes. A preliminary report. Retina 1990; 10:301–314

28.Marshall J. The effects of ultraviolet radiation and blue light on the eye. In: Cronly-Dillon J (ed) Susceptible Visual Apparatus (Vision and Visual Dysfunction; vol. 16). London: Macmillan, 1991

29.Rapp LM, Smith SC. Morphologic comparisons between rhodopsin-mediated and short-wavelength classes of retinal light damage. Invest Ophthalmol Vis Sci 1992; 33:3367–3377

30.Pang J, Seko Y, Tokoro T, Ichinose S, Yamamoto H. Observation of ultrastructural changes in cultured retinal pigment epithelium following exposure to blue light. Graefe’s Arch Clin Exp Ophthalmol 1998; 236:696–701

31.Sparrow JR, Cai B. Blue light-induced apoptosis of A2Econtaining RPE: involvement of caspase-3 and protection by Bcl-2. Invest Ophthalmol Vis Sci 2001; 42:1356–1362

32.Schutt F, Davies S, Kopitz J, Holz FG, Boulton ME. Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin. Invest Ophthalmol Vis Sci 2000; 41:2303–2308

33.Sparrow J, Miller A, Zhou J. Blue light-absorbing intraocular lens and retinal pigment epithelium protection in vitro. J Cataract Refract Surg 2004; 30:873–878

34.Lerman S, Borkman R. Spectroscopic evaluation of classification of the normal, aging and cataractous lens. Opthalmol Res 1976; 8:335–353

35.Data on file, Alcon Laboratories, Fort Worth, TX, USA

36.Lerman S, Borkman R. Spectroscopic evaluation of classification of the normal, aging and cataractous lens. Opthalmol Res 1976; 8:335–353

37.Yuan Z, Reinach P, Yuan J. Contrast sensitivity and color vision with a yellow intraocular lens. Am J Ophthalmol 2004; 138:138–140

38.Ishida M, Yanashima K, Miwa W, et al [Influence of the yellow-tinted intraocular lens on spectral sensitivity] (Article in Japanese). Nippon Ganka Gakkai Zasshi 1994; 98(2):192–196

39.Niwa K, Yoshino Y, Okuyama F, Tokoro T. Effects of tinted intraocular lens on contrast sensitivity. Ophthalmic Physiol Opt 1996; 16(4):297–302

40.Cionni R, Tsai J. Color perception evaluation of the AcrySof natural IOL and the AcrySof single piece IOL in photopic and mesopic conditions. J Cataract Refract Surg

41.Wyszecki G, Stiles WS. Color Science Concepts and Methods, Quantitative Data and Formulae. 2nd edn. Wiley, New York, 1982

42.Swanson WH, Cohen JM. Color vision. Ophthalmol Clin N Am 2003; 16:179–203

43.Jackson G. Pilot study of the effect of a blue-light-blocking IOL on Rod-Mediated (Scotopic) vision. In: ASCRS Annual Meeting, 2005

44.Munz F, McFarland W. Evolutionary adaptations of fishes to the photic environment. In: Crescitelli F (ed) The Visual System of Vertebrates. Springer, New York, 1977, pp 194–274

45.Turner P, Mainster M. Circadian photoreception: ageing and the eye’s important role in systemic health. Br J Ophthalmol 2008; 92:1439–1444; Review

46.Patel AS, Dacey DM. Relative effectiveness of a blue lightfiltering intraocular lens for photoentrainment of the circadian rhythm. J Cataract Refract Surg 2009; 35:529–539

47.Landers J, Tamblyn D, Perriam D. Effect of a blue-light- blocking intraocular lens on the quality of sleep. J Cataract Refract Surg 2009; 35:83–88