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216

J. L. Alió and P. Klonowski

Fig. 8.8 AcriFlex MICS 46CSE IOL

Fig. 8.9 Hoya Y-60H MICS

IOL

8.1.2.10Miniflex IOL (Mediphacos Ltda., Minas Gerais, Brasil)

This is also a new MICS lens and can be implanted through 1.8 mm incision. The material is Flexacryl® Hybrid Acrylic which brings together hydrophobic and hydrophilic monomers. The optics is aberration neutral. The lens can be implanted through 1.8 mm incision using a docking technique. The lens was presented on ESCRS 2008 in Berlin by Carlos Verges (Fig. 8.10).

Fig. 8.10 Miniflex IOL

8.1.3 Optical Quality of MICS IOLs

As an important parameter for adequate IOL performance, we have evaluated objectively the optical quality of MICS IOLs and compared it with that of the conventional ones [3]. The optical quality was studied by the MTF for monochromatic light using the optical quality analysis system (OQAS, Visiometrics S.L.) at a spatial frequency of 0.5 and 0.1 MTF of the different IOLs.

Two MICS IOLs (UltraChoice 1.0, ThinOptX, and Acri.Smart 48S, Acri.Tec) were evaluated and compared with one conventional small-incision IOL (AcrySof MA60BM, Alcon Laboratories). The results showed that MICS IOLs have excellent MTF performance when implanted after cataract surgery, equal to that of conventional IOLs (Fig. 8.11).

For the Acri.Smart 48S IOL, the point-spread function (PSF) was evaluated before and after pushing the lens through the Acri.Glide cartridge (Acri.Tec GmbH). After 120 min., no difference between the untreated and treated Acri.Smart could be detected (Fig. 8.12).

Also, in the ThinOptX UltraChoice 1.0 IOL through its tandem fashion of working, each stepped ring provides the same optical information to the same focal point on the retina and MTF and visual acuity are therefore excellent (Fig. 8.13) [23].

We also evaluated the intraocular optical quality of a new MICS IOL Akreos MI60 (Bausch & Lomb) by using our model of intraocular optical quality analysis [24]. With regard to the Strehl ratio, it was 0.26 ± 0.03. The mean value of 0.5 MTF was 3.0 ± 0.5 cycles per degree (cpd) and the mean of MTF cut-off value was 22.3 ± 7.9 cpd (Fig. 8.14).

In order to show the intraocular optical performance of the IOL, intraocular aberrations for a typical eye implanted with Akreos MI60 are shown in (Fig. 8.15) for a 6 mm pupil.

8 IOL Types and Implantation Techniques

217

12.000

0.5 MTF

0.1 MTF

10.000

(cpd)

8.000

SpatialFrequency

4.000

 

6.000

2.000

0.000 Ultrachoice Acri.Smart AcrySof

IOL

Fig. 8.11 Spatial frequency (cpd) for 0.5 and 0.1 MTF values of Acri.Smart, ThinOptX and AcrySof IOLs [3]

a

b

Fig. 8.12 Acri.Smart lens (a) Acri. Smart lens. (b) Optical quality analysis system (OQAS) image as detected following implantation of the lens [23]

These results showed that MI60 IOL fulfills all the requirements for the modern trend in cataract surgery and MICS, with excellent intraocular optical performance once implanted inside the eye [26].

8.1.4 Conclusion

The number of lenses available for MICS is increasing. Now we have some microincisional lenses which can be injected through sub-2 mm incisions, with clinical data which confirm their perfect characteristics. The decrease of the incision and excellent quality of vision following the surgery, jointly with multifocal capacity to correct refractive errors with precision, makes cataract surgery a part of the refractive surgery. Now we know that MICS lenses have an optical quality equal to or superior to conventional lenses for standard cataract surgery. MICS lenses have excellent capsular bag stability and PCO rate. With the result of postoperative vision after MICS technique and MICS IOLs, we can expect an improvement in the refractive result and optical quality of the eye. In the future an

MTF 1.00

Frequency at 0.5 height (c/d): 3.527

0.83

0.67

0.50

0.33

0.17

0.00

 

 

 

 

 

 

0.00

17.02

34.05

51.07

68.09

85.12

102.14

c/d

218

 

 

 

J. L. Alió and P. Klonowski

a

b

 

 

 

 

 

 

 

MTF

 

 

 

 

 

 

 

1.00

Frequency at 0.5 height (c/d): 2.200

 

 

 

 

 

0.83

 

 

 

 

 

 

 

0.67

 

 

 

 

 

 

 

0.50

 

 

 

 

 

 

 

0.33

 

 

 

 

 

 

 

0.17

 

 

 

 

 

 

 

0.00

 

 

 

 

 

 

 

0.00

17.02

34.05

51.07

68.09

85.12

102.14

 

 

 

 

c/d

 

 

 

Fig. 8.13 The ThinOptX IOL (a) The ThinOptX IOL. (b) OQAS image as detected, following implantation of the lens [23]

Fig. 8.14 HOA, PSF and MTF graphs after surgery of the MI60 IOL at 6 mm pupil diameter, with E-Snellen simulation

8 IOL Types and Implantation Techniques

219

INTRAOCULAR ABERRATIONS

(microns)

2.5

2

1.5

 

value

1

0.5

RMS

0

RMS

TOT

RMS

LO

RMS

HO

TILT

ASTIG

SPHERICA

COMA

 

 

 

 

 

 

 

 

 

 

Fig. 8.15 Wavefront intraocular aberrations after surgery of the MI60 IOL

explosive development of MICS IOLs is expected to follow the demand of progress in cataract surgery.

Take Home Pearls

ßTen types of lenses are available today to be used in MICS sub-2 mm

ßMICS lenses fulfill all the demands of modern cataract lenses

ßModern IOL design, higher index of refraction and improved Abbey factor are the ways to

improve MICS IOLs

References

1.Bellucci R, Morselli S. Optimizing higher-order aberrations with intraocular lens technology. Curr Opin Ophthalmol 2007; 18:67–73

2.Alio J, Elkady B, Ortiz D, Bernabeu G. Microincision multifocal intraocular lens with and without a capsular tension ring Optical quality and clinical outcomes. J Cataract Refract Surg 2008; 34(9):1468–1475

3.Alió JL, Schimchak P, Montés-Micó R, Galal A. Retinal image quality after microincision intraocular lens implantation. J Cataract Refract Surg 2005; 31:1557–1560

4.Elkady B, Alió JL, Ortiz D, Montalbán R. Corneal aberrations after microincision cataract surgery. J Cataract Refract Surg. 2008; 34:40–45

5.Wehner W. Microincision intraocular lens with plate haptic design. Evaluation of rotational stability and centering of a microincision intraocular lens with plate haptic design in 12–19 months of follow-up Ophthalmologe 2007; 104: 393–394

6.Lubiñski W, Podboraczyñiska-Jodko K, Barnyk K,

Karczewicz D. Microincision cataract surgery with implan-

tation of an Acri.Smart 48S lens Klin Oczna 2007; 109: 267–271

7.Mencucci R, Ponchietti C, Nocentini L, Danielli D, Menchini U. Scanning electron microscopic analysis of acrylic intraocular lenses for microincision cataract surgery. J Cataract Refract Surg 2006; 32:318–323

8.Synder A, Omulecki W, Wilczyñski M, Wilczyñska O. Results of bimanual phacoemulsification with intraocular lens implantation through the micro incision Klin Oczna 2006; 108:20–23

9.Alió JL, Rodriguez-Prats JL, Vianello A, Galal A. Visual outcome of microincision cataract surgery with implantation of an Acri.Smart lens. J Cataract Refract Surg 2005; 31:1549–1556

10.Cavallini GM, Pupino A, Masini C, Campi L, Pelloni S. Bimanual microphacoemulsification and Acri.Smart intraocular lens implantation combined with vitreoretinal surgery. J Cataract Refract Surg 2007; 33:1253–1258

11.Kurz S, Krummenauer F, Thieme H, Dick HB. Contrast sensitivity after implantation of a spherical versus an aspherical intraocular lens in biaxial microincision cataract surgery. J Cataract Refract Surg 2007; 33:393–400

12.Dogru M, Honda R, Omoto M, Fujishima H, Yagi Y, Tsubota K, Kojima T, Matsuyama M, Nishijima S, Yagi Y. Early visual results with the rollable ThinOptX intraocular lens.

J Cataract Refract Surg 2004; 30:558–565 (Erratum in: J Cataract Refract Surg 2004; 30:1154)

13.Pandey SK, Werner L, Agarwal A, Agarwal A, Lal V, Patel N, Hoyos JE, Callahan JS, Callahan JD. Phakonit cataract removal through a sub-1.0 mm incision and implantation of the ThinOptX rollable intraocular lens. J Cataract Refract Surg 2002; 28:1710–1713

14.Kaya V, Oztürker ZK, Oztürker C, Yasar O, Sivrikaya H, Ağca A, Yilmaz OF. ThinOptX vs AcrySof: comparison of visual and refractive results, contrast sensitivity, and the

incidence of posterior capsule opacification. Eur J Ophthalmol 2007; 17:307–314

15.Cinhüseyinoglu N, Celik L, Yaman A, Arikan G, Kaynak T, Kaynak S. Microincisional cataract surgery and Thinoptx rollable intraocular lens implantation. Graefes Arch Clin Exp Ophthalmol 2006; 244:802–807

16.Prakash P, Kasaby HE, Aggarwal RK, Humfrey S. Microincision bimanual phacoemulsification and Thinoptx implantation through a 1.70 mm incision. Eye 2007; 21:177–182

17.Amzallag T. The Akreos micro-incision lens A clinical eval-

uation of an IOL for microincisional cataract surgery. J Cataract Refract Surg Today 2006; 4:32–34

18.Nichamin L, Amzallag T. Akreos scores highly for stability and centration Eurotimes 2007; 4:23

19.Doane JF, Jackson RT. Accommodative intraocular lenses: considerations on use, function and design. Curr Opin Ophthalmol 2007; 18:318–324; Review

20.Wolffsohn JS, Naroo SA, Motwani NK, Shah S, Hunt OA, Mantry S, Sira M, Cunliffe IA, Benson MT. Subjective and objective performance of the Lenstec KH-3500 “accommodative” intraocular lens. Br J Ophthalmol 2006; 90:693–669

21.Kellan R. An accommodative IOL with a new approach. Cataract Refract Surg Today 2004; 4:35–36

22.Tsuneoka H. Implantation of a new Hoya-IOL, Y-60H, through a 1.7mm corneal incision. In: Packer M (eds)

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Mastering the Techniques of Advanced Phaco Surgery. Jaypee, New Deli, 2008, pp 209–213

23.Alio J, Rodriguez-Prats JL, Galal A. Advances in microincision cataract surgery intraocular lenses. Curr Opin Ophthalmol 2006; 17:80–93

24.Ortiz D, Alió JL, Bernabeu G, Pongo V. Optical quality performance inside the human eye of monofocal and multifocal intraocular lenses. J Cataract Refract Surg 2008; 34:755–762

25.Alio JL, Rodriguez Prats JL, Galal A. MICS Micro-Incision Cataract Surgery. Highlights of Ophthalmology International, Miami, 2004

26.Alio J, Elkady B, Ortiz D, Bernabeu G. Clinical outcomes and intraocular optical quality of a diffractive multifocal

intraocular lens with asymmetrical light distribution. J Cataract Refract Surg 2008; 34(6):942–948

8.2 Implantation Techniques

T. Amzallag

Core Messages

ßTo inject an intraocular lens (IOL) through a sub-2 mm corneal incision a wound-assisted

visco-injection technique is generally required.

ßIt is mandatory to understand the IOL characteristics (material, design) and to know how to

handle the dedicated injectors.

ßThe wound-assisted injection technique is the most used as it enables the smallest incision

size, to date.

ßAt every step, the surgeon should keep in mind the exact incision plane in order to follow it

closely when injecting.

ßThe precise loading of the IOL in the cartridge, the loading of the cartridge in the injector and

the injection itself should fulfill very precise rules in order to lead to reliable and reproducible results.

Implantation of an intraocular lens through a microincision requires a new technological as well as technical approach, especially as the incision size is decreasing.

A new technological approach is necessary as both the implants and the injectors need to have the expected efficiency.

In spite of the reduction in the volume of the implant, it should have mechanical strength and, after being injected, should maintain the standards of optical quality and postoperative intra-saccular behavior, similar to the best products available.

The injectors and cartridges should be microincisioncompatible. Today, it is indeed the internal diameter of the cartridge that determines the incision size. In practice, the internal diameter of the cartridge should be less than 1.4mm while using the wound-assisted technique

T. Amzallag

Ophthalmic Institute of Somain,

28 rue Anatole France, 59490, Somain, France e-mail: thierry.amzallag@institut-ophtalmique.fr