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228

L-S. Leung et al.

and positional cues inside the eye [117, 120]. Under the operating microscope, an eccentric light source casts shadows of instruments on the retina, allowing the surgeon to determine the depth and position of the instruments relative to other structures in the eye. These shadows are absent in endoscopic surgery; moreover, the field of view is limited and focus is achieved not by adjusting the microscope, but with miniscule movements of the hand and fingers. These difficulties translate to an increased risk of incidental contact with structures inside the eye, including the crystalline lens. There have been reports of iatrogenic retinal breaks during endoscopic removal of lens fragments [131], believed to be directly related to inexperience in maneuvering the endoscope inside the eye. However, with more experience, an increasing facility and technical skill is expected.

10.4Future Directions of Minimally Invasive Vitreoretinal Surgery

While small-incision surgery is advancing rapidly and being adopted by the retinal physician community, there remain limitations to what microinstrumentation can accomplish. Thus, incorporation of advances in pharmacologic treatment [133], and in robotic technology may expand the capability of managing retinal diseases with a surgical approach. These efforts are already in progress and as new technologies and treatments are introduced the microincision platform should result in greater efficacy and safety of vitreoretinal surgery.

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