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10 Minimally Invasive Vitreoretinal Surgery

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longer [97]. In this approach, only two incisions are necessary – one for illumination and one for a forceps that can be used to elevate the edge of the epiretinal membrane and grasping it. The smaller fiber must be connected to a very bright light source, and the tip of the light fiber must be modified to expand the angle of illumination.

The utilization of small-gauge vitreoretinal surgery has gradually increased, and many surgeons have advocated that at least 23 gauge will become the new standard for vitreoretinal surgery [98–101]. The advantages of the transconjunctival sutureless approach seem to be mainly intangible ones at this time. The main advantages – reduced postoperative pain [102], transient reduction of corneal astigmatism [103, 104], and faster recovery time – are difficult to quantify and measure. However, patients do seem to appreciate the advantages and frequently comment how there was no pain or discomfort. There are relatively few randomized clinical studies that prospectively measure the advantages of small-gauge vitrectomy compared to the conventional 20-gauge approach [15, 23, 59, 105–109]. Critics indicate that the small-gauge instrumentation is more costly, and presents an unacceptable rate of endophthalmitis [110, 111]. Until tangible advantages can be demonstrated, universal acceptance by retinal surgeons will be delayed. Continued advancements in technology will also convince surgeons that the smaller gauge format will provide the same or better performance than the conventional 20-gauge system.

10.3 Endoscopic Vitreoretinal Surgery

10.3.1 Introduction

The first endoscopic vitreoretinal procedure was described in 1934 by Thorpe for removal of a nonmetallic intravitreal foreign body [112, 113]. In the intervening 75 years, the application of endoscopic viewing systems had primarily been limited to foreign body extraction [113, 114]. Especially with the development of modern vitrectomy techniques and technology pioneered by Machemer, the uses for endoscopes that were unwieldy and difficult to navigate in the intraocular cavity have been seemingly few. However, technical advances have allowed for improved image

resolution and transmission and smaller and more flexible instrumentation for improved maneuverability and visualization of the eye as well as the ability to use existing surgical incisions [115–117]. Consequently, there is an expanding set of applications for endoscopy in many types of ophthalmic surgery [112, 118].

10.3.2History and Development of Endoscopic Ophthalmic Surgery

Early intraocular endoscopy required external fixation, with the surgeon looking through a rigid scope composed of classical lenses [113, 119, 120]. The development of fiber-optic technology allowed for flexible endoscopes which were both easier to manipulate and maneuver, and allowed for images to be seen from a distance. The charge-coupled device was first developed in 1983, allowing an image to be transmitted electronically to a monitor or video recording device [121]. In addition, improved ability to manufacture optical fibers enabled both smaller and higher resolution endoscopes.

10.3.3 The Endoscope

Endoscopes using classical lenses have a minimum diameter of 1.3–2.0 mm, too large for use in ophthalmic surgery [113, 119]. Ophthalmic endoscopes currently in use typically employ one of two different modes of image transmission. Fused fiber-optic endoscopes transmit segmented images (image blocks or pixels partitioned into homogeneous groups such as color) through single fibers, allowing for long-distance transmission. However, image resolution is often limited by image segmentation. Gradient-index (GRIN) endoscopes, in contrast, transmit whole images through a single rod of varying refractive indices, allowing for refraction and transmission of light across flat surfaces without the minimal size limitations of classical lenses [119]. Both types of endoscopes are small enough to fit through a standard 20-gauge vitrectomy incision. However, GRIN lenses are available with a much smaller diameter of 0.35 or 0.5 mm and can be paired with two additional channels for illumination and laser and/or irrigation/aspiration, for a total