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Ординатура / Офтальмология / Английские материалы / Minimally Invasive Ophthalmic Surgery_Fine, Mojon_2010.pdf
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5 Minimally Invasive Refractive Surgery

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had uncorrected distance acuity of 20/32 or better and 98.9% had best corrected distance acuity of 20/25 or better. The safety index and efficacy index for distance vision of the procedure was 2.5 and 1.8 respectively. Another study also showed MICS does not degrade the optical quality of the cornea or induce a modification in corneal astigmatism [23].

Thus, we can see that MICS is able to achieve the aims of minimal incision surgery for cataract surgery and is a key factor in achieving optimal refractive outcomes in presbyopic patients with cataracts.

5.5.2 The Ideal MICS Intraocular Lens

Pseudophakic intraocular lenses (IOLs) have evolved in tandem with cataract surgery. In order to take advantage of the sub-2.0 mm incision possible with MICS, refractive surgeons must be able to implant the pseudophakic IOLs through these small incisions. In addition, the IOLs should be multi-focal IOLs to correct both ammetropia and presbyopia at the same time. Evolution of aspheric and toric lenses has also taken place which may further improve the outcomes of cataract surgery.

The criteria for the ideal MICS IOL is very stringent. The ideal MICS IOL will have to fulfil the following criteria:

1.Able to be implanted through a sub-2 mm incision

2.Able to correct presbyopia

3.Have an aspheric design

4.Have a toric model available

5.5.2.1 Aspheric Intraocular Lenses

The cornea has a prolate surface with positive sphericity while the natural crystalline lens has a negative sphericity. Conventional pseudophakic IOLs have positive sphericity and these result in an increase in total optical aberrations, especially spherical aberrations, post-cata- ract surgery [26]. These aberrations play a substantial role in degrading visual performance when the pupil is large, i.e. scotopic night conditions [37]; hence, the development of aspheric IOLs. These aspheric designs are intended to reduce or eliminate the spherical aberration of the eye and improve functional vision as compared with a spherical pseudophakic implant.

Studies have demonstrated reduction or elimination of spherical aberration with the Tecnis IOL (AMO, Santa Ana, CA, USA) when compared with conventional spherical IOLs [11, 12, 18, 34, 44]. Eyes with the Tecnis Z9001 IOL with a modified anterior aspheric surface induced significantly less higher-order aberration and spherical aberration compared to the spherical Clariflex IOL (AMO, Santa Ana, CA, USA). Contrast sensitivity also revealed better values under photopic and mesopic conditions with the Tecnis Z9001 IOL [62]. Recent studies also supported reduction of spherical aberration and showed superior functional vision with the AcrySof IQ IOL (Alcon, Fort Worth, TX, USA) compared to spherical IOLs [7, 55].

Caporossi et al. compared patients who were randomly assigned to receive either IOLs with a spherical biconvex optic (Acrysof SN6OAT [Alcon] or Sensar AR40e [Advanced Medical Optics, AMO]) or IOLs with an aspheric optic (Acrysof IQ SN6OWF [Alcon], Tecnis Z9000 [AMO] or Sofport L161AO [Bausch & Lomb]) [15]. Their study showed that aspheric IOLs showed better contrast sensitivity compared to spherical IOLs at spatial frequencies of 6, 12, and 18 cycles per degree (cpd) under photopic conditions and at all spatial frequencies under mesopic conditions. Mean total spherical aberration was statistically lower in dominant eyes with aspheric IOLs (0.05 ± 0.06, 0.11 ± 0.1, and 0.19 ± 0.08 mm for the Tecnis Z9000, Acrysof IQ SN6OWF and Sofport L161AO, respectively) compared with eyes with spherical IOLs (0.62 ± 0.24 and 0.46 ± 0.19 mm for the Acrysof SN6OAT and Sensar AR40e, respectively) for a 5-mm pupil diameter. This showed that the aspheric IOLs had less wavefront aberrations and performed better under both photopic and mesopic contrast sensitivity compared to the spherical IOLs.

Thus, we can see that the visual performance, especially in scotopic conditions, is improved with aspheric IOLs.

5.5.2.2 Toric Intraocular Lenses

Correcting post-cataract surgery astigmatism, either due to pre-existing astigmatism or surgically induced astigmatism, has always been a challenge for refractive surgeons. As discussed earlier, surgically induced astigmatism can be reduced by MICS. However, correction of pre-existing astigmatism remains. Moderate