- •Dedication
- •Preface
- •Acknowledgements
- •Contributors
- •Contents
- •1. Minimally Invasive Oculoplastic Surgery
- •1.1 General Points
- •1.2 Lower Lid Entropion
- •1.2.1 Introduction
- •1.2.2 Lower Lid Entropion Sutures
- •1.2.3 Lower Lid Entropion Botulinum Toxin
- •1.3 Lower Lid Ectropion
- •1.3.1 Introduction
- •1.3.2 The Royce Johnson Suture
- •1.3.3 The Pillar Tarsorrhaphy
- •1.4 Distichiasis
- •1.4.1 Introduction
- •1.4.2 Direct Excision of Lashes
- •1.5 Ptosis
- •1.5.1 Introduction
- •1.5.3 Anterior Approach – One Stitch Aponeurosis Repair
- •1.5.4 Supramid Brow Suspension
- •1.6 Lid Retraction
- •1.6.1 Introduction
- •1.6.2 Koornneef Blepharotomy
- •1.6.3 Botulinum Toxin
- •1.7 Lid Tumours
- •1.7.1 Mohs’ Micrographic Surgery
- •1.7.2 Lamella Sparing Tumour Excision
- •References
- •2. Minimally Invasive Conjunctival Surgery
- •2.1 Conjunctival Surgery
- •2.2 Conjunctivochalasis
- •2.2.1 Background of the Disease
- •2.2.2 Indication for Surgery
- •2.2.3 Basic Concept of Surgery
- •2.2.4 Surgical Procedure
- •2.2.5 Postoperative Follow-Up
- •2.3 Pterygium
- •2.3.1 Background of the Disease and the Concept of Minimally Invasive Surgery
- •2.3.2 Indication for Surgery
- •2.3.3 Basic Concept of Surgery
- •2.3.4 Surgical Procedures
- •2.3.5 A Biologic Adhesive for Sutureless Pterygium Surgery
- •2.3.6 Postoperative Follow-Up
- •2.4 Limbal and Conjuntival Dermoids
- •2.4.1 Background of the Disease
- •2.4.2 Basic Concept of Surgery
- •2.4.3 Surgical Procedure
- •2.4.4 Postoperative Follow-Up
- •2.5 Strabismus Surgery
- •2.6 Conclusion
- •References
- •3. Minimally Invasive Lacrimal Surgery
- •3.1 Introduction
- •3.1.1 Causes of Stenoses of the Lacrimal Drainage System
- •3.1.3 General Remarks Regarding Surgical Management
- •3.2 Endonasal Endoscopic (Microscopic) Dacryocystorhinostomy (EDCR)
- •3.2.1 Indication for EDCR
- •3.2.2 Surgical Technique
- •3.2.3 Silicone Stenting for EDCR
- •3.2.2.1 Silicone “Cones” (Lacrimal Duct Stent, Bess, Berlin)
- •3.2.4 Use of Mitomycin C for EDCR
- •3.2.5 Post-Operative Care After EDCR
- •3.2.6 Results of EDCR
- •3.3 Endonasal Endoscopic Laser Dacryocystorhinostomy (ELDCR)
- •3.3.1 Indications for ELDCR
- •3.3.2 Contraindications for ELDCR
- •3.3.3 Surgical Technique for ELDCR
- •3.3.4 Potential Problems with ELDCR
- •3.3.5 Post-Operative Care After ELDCR
- •3.3.6 Results of ELDCR
- •3.4 Dacryoendoscopy with Transcanalicular Laserdacryoplasty (TLDP)
- •3.4.1 Indication for TLDP
- •3.4.2 Contraindication for TLDP
- •3.4.3 Surgical Technique for TLDP
- •3.4.4 Results of TLDP
- •3.5 Microdrill Dacryoplasty (MDP)
- •3.5.1 Indication for MDP
- •3.5.2 Contraindication for MDP
- •3.5.3 MDP Procedure
- •3.5.4 Results of MDP
- •3.6 Balloon Dilatation
- •3.6.1 Indications for Balloon Dilatation
- •3.6.2 Anaesthesia for Balloon Dilatation
- •3.6.3 Surgical Technique with 2 mm or 3 mm Balloon for Incomplete Stenosis
- •3.6.3.1 Post-Operative Care
- •3.6.3.2 Complications
- •3.6.3.3 Results
- •3.6.4.1 Post-Operative Care
- •3.6.4.2 Results
- •3.6.4.3 Complications
- •3.7 Stent Placement
- •3.7.1 Indications for Stent Placement
- •3.7.3 Surgical Technique for Stent Placement
- •3.7.5 Results of Stent Placement
- •References
- •4. Minimally Invasive Corneal Surgery
- •4.1 Penetrating Keratoplasty
- •4.1.1 Introduction
- •4.1.2 Indications
- •4.1.3 Preoperative Evaluation of the Keratoplasty Patient
- •4.1.4 Preparation for Penetrating Keratoplasty
- •4.1.4.1 Eyelid Speculum
- •4.1.4.2 Scleral Fixation Rings
- •4.1.4.3 Large and Fine-Tipped Needle Holder
- •4.1.4.4 Toothed Forceps
- •4.1.4.5 Trephine Blades
- •4.1.4.6 Radial Marker
- •4.1.4.7 Cornea Punch
- •4.1.4.8 Cutting Block
- •4.1.4.9 Scissors
- •4.1.4.10 Cannulas and Blades
- •4.1.5 Preoperative Medications
- •4.1.6 Penetrating Keratoplasty Surgical Procedure
- •4.1.6.1 Placement of the Scleral Fixation Ring
- •4.1.6.2 Marking of the Host Cornea
- •4.1.6.3 Sizing of the Trephine
- •4.1.6.4 Trephination of the Host Cornea
- •4.1.6.5 Trephination of the Donor Cornea
- •4.1.6.6 Removal of the Host Cornea
- •4.1.6.7 Placement of the Donor Cornea Tissue in the Host Stromal Bed
- •4.1.6.8 Placement of the Cardinal Sutures
- •4.1.6.9 Completion of Suturing
- •4.1.6.10 Suture Techniques
- •4.1.6.11 Subconjunctival Medications
- •4.1.7 Intraoperative Complications
- •4.1.7.1 Scleral Perforation
- •4.1.7.2 Damage to the Donor Button
- •4.1.7.4 Posterior Capsule Rupture
- •4.1.7.5 Vitreous Loss
- •4.1.7.6 Anterior Chamber Hemorrhage
- •4.1.7.7 Choroidal Hemorrhage
- •4.1.8 Postoperative Management
- •4.1.8.1 Postoperative Immunosuppressive Regimen
- •4.1.9 Postoperative Complications
- •4.1.9.1 Wound Leaks
- •4.1.9.2 Epithelial Defects
- •4.1.9.3 Suture-Related Problems
- •4.1.9.4 Increased Intraocular Pressure
- •4.1.9.5 Post-Keratoplasty Astigmatism
- •4.1.10.1 Wedge Resections and Compression Sutures
- •4.1.10.2 Relaxing Incisions
- •4.1.10.3 LASIK
- •4.1.10.4 Photorefractive Keratectomy with Mitomycin C
- •4.1.11 Corneal Allograft Rejection
- •4.1.11.1 Host Risk Factors
- •4.1.11.2 Vascularized Corneas
- •4.1.11.3 Prior Graft Loss
- •4.1.11.4 Graft Diameter
- •4.1.11.5 Anterior Synechiae
- •4.1.11.6 Previous Intraocular Surgery
- •4.1.11.7 Herpes Simplex
- •4.1.12 Treatment of Allograft Rejection
- •4.1.13 Large Diameter Penetrating Keratoplasty
- •4.1.14 Summary
- •References
- •4.2 Descemet’s Stripping Endothelial Keratoplasty
- •4.2.1 Introduction
- •4.2.2 Descemet’s Stripping Endothelial Keratoplasty Surgical Technique
- •4.2.2.1 Donor Cornea Preparation
- •4.2.2.2 Host Cornea Preparation
- •4.2.2.3 Insertion of the Donor Cornea
- •4.2.3 Postoperative Medications
- •4.2.4 Donor Dislocation Risks
- •4.2.5 Repositioning Donor Tissue
- •4.2.6 Treatment of Rejection Episodes
- •4.2.7 Visual and Refractive Outcomes
- •4.2.8 Other Complications
- •4.2.9 Summary
- •References
- •4.3 Pterygium
- •4.3.1 Introduction
- •4.3.2 Treatment of Pterygium
- •4.3.3 Surgical Technique
- •4.3.3.1 Removal of the Pterygium
- •4.3.3.2 Harvesting the Conjunctival Autograft
- •4.3.3.3 Securing the Conjunctival Autograft
- •4.3.3.4 Fibrin Glue vs. Nylon Sutures
- •4.3.4 Postoperative Management
- •4.3.5 Recurrent Pterygium
- •4.3.6 Other Techniques in Pterygium Removal
- •4.3.6.1 Bare Scleral Technique
- •4.3.6.2 Adjunctive Agents
- •Mitomycin C
- •Beta-Irradiation
- •4.3.6.3 Amniotic Membrane Transplantation
- •4.3.7 Complications in Pterygium Removal
- •4.3.8 Summary
- •References
- •5. Minimally Invasive Refractive Surgery
- •5.1 Trends in Refractive Surgery
- •5.2 Introduction
- •5.3 Cornea Refractive Surgery
- •5.3.1 Laser In Situ Keratomileusis (LASIK)
- •5.3.1.1 Advances in Flap Creation Technology
- •Microkeratomes
- •Femtosecond Laser
- •5.3.1.2 Technological Advances in Laser Delivery Platforms
- •5.3.1.3 Faster Excimer Lasers
- •5.3.1.4 Reduction of Collateral Thermal Tissue Damage
- •5.3.1.5 Advanced Eye Trackers
- •5.3.2 PRK and Advanced Surface Ablations (ASA)
- •5.3.2.1 Decrease Thermal Load on the Cornea
- •5.3.2.2 Use of Wound-Healing Modulators
- •5.3.2.3 Trend Towards EPI-LASIK
- •5.3.3 Summary
- •5.4 Intraocular Refractive Surgery
- •5.4.1 Phakic Intraocular Lens Surgery
- •5.4.1.1 Advances in Diagnostic Equipment
- •5.4.1.2 Types of Phakic Intraocular Lens
- •5.4.1.3 Kelman-Duet Phakic Intraocular Lens
- •Lens Design
- •Surgical Technique
- •Pre-Operative Preparation
- •Operative Procedure
- •Post-Operative Care
- •Results
- •Refractive Outcomes
- •Corneal Endothelium
- •5.4.1.4 Visian Implantable Collamer Lens
- •Lens Design
- •Surgical Technique
- •Pre-Operative Preparation
- •Operative Procedure
- •Post-Operative Care
- •5.4.1.5 Results
- •5.4.2 Summary
- •5.5 Lens and Cataract Surgery
- •5.5.2 The Ideal MICS Intraocular Lens
- •5.5.2.1 Aspheric Intraocular Lenses
- •5.5.2.2 Toric Intraocular Lenses
- •5.5.2.3 ACRI.LISA 366D and ACRI.LISA TORIC 466TD
- •Lens Design
- •5.5.2.4 Surgical Technique
- •Operative Procedure
- •Post-Operative Care
- •5.5.2.5 Results
- •5.5.3 Summary
- •5.6 The Future: Beyond the Horizon of Refractive Surgery Today
- •Reference
- •6. Minimally Invasive Strabismus Surgery
- •6.1 Introduction
- •6.2 Nonsurgical Treatment
- •6.4 Rectus Muscle Procedures
- •6.4.1 MISS Rectus Muscle Recession
- •6.4.2 MISS Rectus Muscle Plication
- •6.4.3 Parks’ Rectus Muscle Recession
- •6.4.4 Parks’ Rectus Muscle Plication
- •6.4.5 MISS Rectus Muscle Posterior Fixation Suture
- •6.4.7 MISS Rectus Muscle Repeat Surgery
- •6.4.8 MISS Rectus Muscle Transposition Surgery
- •6.5 Oblique Muscle Procedures
- •6.5.1 MISS Inferior Oblique Muscle Recession
- •6.5.2 MISS Inferior Oblique Muscle Plication
- •6.5.3 MISS Superior Oblique Muscle Recession
- •6.5.4 MISS Superior Oblique Muscle Plication
- •6.5.6 Mühlendyck’s Partial Posterior Superior Oblique Tenectomy for Congenital Brown’s Syndrome
- •6.6 Postoperative Handling
- •6.7.1 Intraoperative Complications
- •6.7.2 Postoperative Complications
- •6.8 Suggestions on How to Start Doing MISS
- •6.8.1 Instruments Suitable for MISS
- •6.8.2 Suture Materials Used for MISS
- •6.8.3 General Remarks Regarding MISS Procedures
- •6.8.4 MISS Dose–Response Relationships
- •References
- •7. Minimally Invasive Iris Surgery
- •7.1 Instrumentation
- •7.2 Sutures
- •7.3 Surgical Principles of Iris Suturing
- •7.3.1 Mobilization
- •7.3.2 Intraocular Suturing and Knot Tying
- •7.3.3 Reattachment of Iris to Sclera
- •7.3.4 Pupil Repair
- •7.3.5 Adjunctive Pupil Repair Techniques
- •References
- •8. Minimally Invasive Glaucoma Surgery
- •Introduction
- •8.1.1 Introduction to Deep Sclerectomy
- •8.1.2 Anesthesia
- •8.1.3 Surgical Technique
- •8.1.3.1 Preparation
- •8.1.3.3 Deep Flap Preparation
- •8.1.3.5 Peeling of Schlemm’s Canal and Juxtacanalicular Meshwork
- •8.1.3.6 Drainage Device
- •8.1.3.7 Wound Closure
- •8.1.4 Postoperative Management and Medication
- •8.1.4.1 Medication
- •8.1.4.2 Management
- •8.1.5 Adjunctive Treatments
- •8.1.5.1 Bleb Needling
- •8.1.5.2 Nd:YAG Goniopuncture
- •8.1.6 Complications and Management
- •8.1.6.1 General
- •8.1.6.2 Perioperative Complications
- •8.1.6.3 Early Postoperative Complications
- •8.1.6.4 Late Postoperative Complications
- •Open-Angle Glaucoma
- •Pigmentary Glaucoma
- •Pseudoexfoliation Glaucoma
- •Aphakic Glaucoma
- •Sturge–Weber Syndrome
- •Glaucoma Secondary to Uveitis
- •Congenital and Juvenile Glaucoma
- •Narrow-Angle Glaucoma
- •Posttrauma Angle-Recession Glaucoma
- •Neovascular Glaucoma
- •Narrow-Angle Glaucoma in a Young Patient
- •Pseudophakic Glaucoma with an A/C IOL
- •8.2.1.4 Preoperative Considerations
- •8.2.2 Anesthesia
- •8.2.4 Postoperative Management and Medication
- •8.2.5 Outcomes and Comparison with Other Techniques
- •8.2.6 Complications and Management
- •8.2.6.1 General
- •8.2.6.4 Summary and Key Points
- •References
- •8.3 New Minimally Invasive, Sclerothalamotomy Ab Interno Surgical Technique
- •8.3.1 Introduction to the Sclerothalamotomy Ab Interno
- •8.3.1.1 Indications for the Sclerothalamotomy Ab Interno
- •8.3.2 Anesthesia
- •8.3.3 Surgical Technique
- •8.3.3.1 Preparation
- •8.3.3.2 Diathermy Probe Insertion
- •8.3.4 Postoperative Management and Medication
- •8.3.5 Outcomes and Comparison with Other Techniques
- •8.3.6 Complications and Management
- •8.3.6.1 General
- •8.3.6.3 Conclusions
- •References
- •Type of Glaucoma
- •Stage of Glaucoma
- •Combined Surgery
- •8.4.2 Anesthesia
- •8.4.3 Surgical Technique
- •8.4.3.1 Preparation
- •8.4.3.2 Implantation of the Micro-Bypass Stent
- •8.4.4 Postoperative Management and Medication
- •8.4.5 Outcomes and Combination with Other Techniques
- •8.4.5.1 Trabecular Implant in Refractory Glaucoma Patients
- •8.4.6 Conclusions
- •References
- •9. Minimally Invasive Cataract Surgery
- •10. Minimally Invasive Vitreoretinal Surgery
- •10.1 Introduction
- •10.2 Microincision Vitrectomy
- •10.2.1 Models of Wound Architecture
- •10.2.2 Vitrectomy
- •10.2.3 Adjuncts
- •10.2.4 Common Surgical Techniques
- •10.2.4.1 Macular Surgery
- •10.2.4.2 Proliferative Diabetic Retinopathy
- •10.2.4.3 Retinal Detachment
- •10.2.4.4 Pediatric Vitreoretinal Surgery
- •10.2.5 Complications
- •10.2.6 Future Developments in Minimally Invasive Vitrectomy
- •10.3 Endoscopic Vitreoretinal Surgery
- •10.3.1 Introduction
- •10.3.2 History and Development of Endoscopic Ophthalmic Surgery
- •10.3.3 The Endoscope
- •10.3.4 Applications of Intraocular Endoscopy
- •10.3.4.1 Media Opacity
- •10.3.4.3 PVR and Subretinal Surgery
- •10.3.4.4 Retained Lens Fragments
- •10.3.4.5 Anterior and Retrolental Vitrectomy in Malignant Glaucoma
- •10.3.4.5 Sutured IOL and ECP
- •10.3.5 Limitations and Challenges
- •10.4 Future Directions of Minimally Invasive Vitreoretinal Surgery
- •References
- •INDEX
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pterygium recurrence. Current nonsuture techniques using fibrin gel successfully reduce surgically induced inflammation and shorten surgical time.
2.4 Limbal and Conjuntival Dermoids
2.4.1 Background of the Disease
A limbal dermoid is a congenital disorder, seen mostly at the lower-temporal limbus, and its size becomes slowly larger in proportion to the size of the cornea. It is often associated with a conjunctival dermoid at the temporal area, the size and thickness of which vary in each patient. It can cause both cosmetic abnormality and decreased visual acuity by causing astigmatism. An amblyopic eye must be treated properly by visual rehabilitation, such as the wearing of an eye patch or corrective eye glasses as removal of the limbal dermoid itself does not change the best corrected visual acuity. In addition, preoperative penalization treatment improves the postoperative visual acuity.
cornea. A donor cornea of the same size is then placed in that area and fixed with 10–12 interrupted 10–0 nylon sutures. If the dermoid is large, the conjunctiva is treated with 0.04% MMC for 3 min. It is preferable to remove the conjunctival dermoid at the same time. However, a conjunctival dermoid that has penetrated deeply into the upper-temporal sclera should be left as it is and should not be excised extensively, to avoid severe postoperative complications. Cosmetic recovery is easily achieved.
2.4.4 Postoperative Follow-Up
After keratoplasty, topical antibiotics (e.g., 0.3% ofloxacin eye drops four times daily) and corticosteroids (e.g., 0.1% dexamethasone or 0.1% fluorometholone drops four times daily) are applied for approximately 6 months. Intraocular pressure should be checked regularly as children often suffer from steroid-induced glaucoma. Systemic steroids are not usually necessary for children. Penalization treatment is not usually effective after surgery, and sutures are usually removed during the initial six postoperative months.
2.4.2 Basic Concept of Surgery
To remove limbal dermoid tissue completely and to prevent the occurrence of pseudopterygium after surgery, peripheral tectonic lamellar keratoplasty over the limbus and its adjacent conjunctiva is preferable. Both fresh and preserved donor corneas may be used for this surgery. Limbal dermoids that receive a simple resection frequently develop pseudopterygium due to adjacent conjunctival over-proliferation on the residual dermoid tissue in the cornea. Furthermore, a simple resection cannot remove all the dermoid tissue from the cornea due to corneal thinning. Patients usually undergo the operation when they are 4–6-years-old due to the ease of postoperative care at that age.
2.5 Strabismus Surgery (Fig. 2.7)
Debate can surround the question of the incision size of the conjunctiva in strabismus surgery. It can be proposed that a wider incision, and thus a wider field of operation, must be made to perform a safe and secure surgery. Conversely, it can be argued that a smaller/narrower incision will result in minimizing the amount of conjunctival damage, thus resulting in rapid cosmetic, recovery, with white conjunctiva that is good in appearance. In fact, it has been found that careful management of the outer eye muscles through a small incision can be satisfactorily performed once a physician gains adequate experience with this type of surgery.
2.4.3 Surgical Procedure (Fig. 2.6)
2.6 Conclusion
First, a minimal conjunctival resection is performed before lamellar keratoplasty. Then, the dermoid is marked by a trephine of appropriate size, and the lamellar dissection is performed from the central
In general, a surgery tends to evolve in the direction of becoming less and less invasive. The same holds true for ophthalmic surgery. The purpose of performing
2 Minimally Invasive Conjunctival Surgery |
31 |
Fig. 2.6 Surgical steps of operation for limbal dermoid. Preoperative limbal dermoid (1) is marked with a slightly over-sized trephine (2), dissect out a limbal dermoid and a diseased peripheral cornea with one-half thickness from a central cornea (3), through an adjacent sclera (4). A lamellar cornea graft of the same size is created from a donor cornea (5), placed on the keratectomized bed (6), and sutured with 10–0 nylon interrupted sutures (7). Postoperative manifestation (8)
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
minimally invasive surgery is to avoid excessive postoperative wound healing, especially in areas with fibrovascular overgrowth. As the conjunctiva is a soft, delicate tissue, surgeons must avoid using invasive surgical modalities that promote excessive wound healing
after surgery. One such approach is the use of a small incision. The other approach is the use of AM, MMC treatment, and the postoperative use of immunosuppressives that presumably suppress the TGF-beta signaling pathway and inflammatory cytokine release.
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Fig. 2.7 Small incision made at the bulbar conjunctiva is seen at strabismus surgery
References
1.Hughes WL (1942) Conjunctivochalasis. Am J Ophthalmol 25:48–51
2.Meller D, Tseng SC (1998) Conjunctivochalasis: literature review and possible pathophysiology. Surv Ophthalmol 43:225–232
3.Watanabe A, Yokoi N, Kinoshita S et al (2004) Clinicopathologic study of conjunctivochalasis. Cornea 23: 294–298
4.Yokoi N, Komuro A, Nishii M et al (2005) Clinical impact of conjunctivochalasis on the ocular surface. Cornea 24: S24–S31
5.Li DQ, Meller D, Liu Y et al (2000) Tseng SC: overexpression of MMP-1 and MMP-3 by cultured conjunctivochalasis fibroblasts. Invest Ophthalmol Vis Sci 41:404–410
6.Meller D, Li DQ, Tseng SC (2000) Regulation of collagenase, stromelysin, and gelatinase B in human conjunctival and conjunctivochalasis fibroblasts by interleukin-1beta and tumor necrosis factor-alpha. Invest Ophthalmol Vis Sci 41:2922–2929
7.Höh H, Schirra F, Kienecker C et al (1995) Lidparallele konjunctivale Falten (LIPCOF) sind ein sicheres diagnostisches Zeichen des trockenen Auges [Lid-parallel conjunctival folds are a sure diagnostice sign of dry eye]. Ophthalmologe 92:802–808
8.Otaka I, Kyu N (2000) A new surgical technique for management of conjunctivochalasis. Am J Ophthalmol 129: 385–387
9.Detels R, Dhir SP (1967) Pterygium: a geographic survey. Arch Ophthalmol 78:485
10.Hirst LW (2003) The treatment of pterygium. Surv Ophthalmol 48:145–180
11.Cano-Parra J, Diaz-Llopis M, Maldonado MJ et al (1995) Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium. Br J Ophthalmol 79:439–441
12.Cardillo JA, Alves MR, Ambrosio LE, Poterio MB et al (1995) Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. Ophthalmology 102:1949–1952
13.Chen PP, Ariyasu RG, Kaza V et al (1995) A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium. Am J Ophthalmol 120: 151–160
14.Frucht-Pery J, Siganos CS, Ilsar M (1996) Intraoperative application of topical mitomycin C for pterygium surgery. Ophthalmology 103:674–677
15.Dunn JP, Seamone CD, Ostler HB et al (1991) Development of scleral ulceration and calcification after pterygium excision and mitomycin therapy. Am J Ophthalmol 112: 343–344
16.Dougherty PJ, Hardten DR, Lindstrom RL (1996) Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C. Cornea 15: 537–540
17.McCommbes JA, Hirst LW, Isbell GP (1994) Sliding conjunctival flap for the treatment of primary pterygium. Ophthalmology 101:169–173
18.Uy HS, Reyes JM, Flores JD, Lim-Bon-Siong R (2005) Comparison of fibrin glue and sutures for attaching conjunctival sutografts after pterygium excision. Ophthalmology 112:667–671
19.Koranyi G, Seregard S, Kopp ED (2004) The cut-and-paste: a no suture, small incision approach to pterygium surgery. Br J Ophthalmol 88:911–914
20.Marticorena J, Rodriguez-Ares MT, Tourino R et al (2006) Pterygium surgery: conjunctival autograft using a fibrin adhesive. Cornea 25:34–36
21.Nakamura T, Inatomi T, Sekiyama E et al (2006) Novel Clinical application of sterilized, freeze-dried amniotic membrane to treat patients with pterygium. Acta Ophthalmol Scand 84(3):401–405
22.Sekiyama E, Nakamura T, Kurihara E et al (2007) Novel sutureless transplantation of bioadhesive-coated freeze-dried amniotic membrane for ocular surface reconstruction. IOVS 48:1528–1534
23.Takaoka M, Nakamura T, Sugai H et al (2008) Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. Biomaterials 29:2923–2931
