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Ростовский Государственный Медицинский Университет

Предмет:

Медицина общая

Файл:

Illustrated Tutorials in Ophthalmology Kanski, Bolton 2001

.pdf

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28.03.2026

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Acromegaly


•	Facial coarseness	• Organomegaly
•	Hypertension, diabetes and	• Carpal tunnel syndrome and
	gonadal dysfunction	cardiomyopathy

Visual field defects in pituitary adenomas

Decussating fibres are most vunerable

MRI of pituitary adenoma

Sagittal


Axial	Coronal

Treatment options for pituitary adenomas

Surgery

Radiotherapy

Transfrontal

Trans-sphenoidal

Bromocriptine

Craniopharyngioma

Presents

•In children with endocrine dysfunction

•In adults with visual field defects

The posteriorly crossing fibres are most vunerable

Craniopharyngioma

Meningioma

Typically affect middle-aged women

Junctional scotoma

Tuberculum Sella meningioma

Sphenoid ridge meningioma

Olfactory groove meningioma

PHACOMATOSES

1.Neurofibromatosis

•Type I (NF-1) - von Recklinghausen disease

•Type II (NF-2) - bilateral acoustic neuromas

2.Tuberous sclerosis (Bourneville disease)

3.von-Hippel-Lindau syndrome

4.Sturge-Weber syndrome

Neurofibromatosis type-1 - (NF-1)

•Most common phacomatosis

•Affects 1:4000 individuals

•Presents in childhood

•Gene localized to chromosome 17q11

Café-au-lait spots


	Appear during first year of life	Increase in size and number throughout
	Appear during first year of life	childhood
		childhood

Fibroma molluscum in NF-1

•Appear at puberty

•Pedunculated, flabby nodules consisting of neurofibromas or schwannomas

•Increase in number throughout life

•Frequently widely distributed

Plexiform neurofibroma in NF-1

•	Appear during childhood	• May be associated with
•	Large and ill-defined	overgrowth of overlying skin

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