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Ординатура / Офтальмология / Английские материалы / Illustrated Tutorials in Ophthalmology Kanski, Bolton 2001

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Congenital systemic involvement

Severity of involvement of fetus depends on duration of gestation at time of maternal infestation

 

 

Infestation during late pregnancy

Chorioretinal scarring at macula

may cause hydrocephalus

which may be bilateral

 

 

Toxoplasma retinitis

Recurrence of healed congenital lesion

Usually between ages 10-35 years.

 

 

Unifocal retinitis adjacent to old scar

Vitritis may be severe

- heals within 1 to 4 months

- ‘headlight in fog’

 

 

Treatment of toxoplasma retinitis

Indications

Lesions at posterior pole, near optic disc or major blood vessel

Very severe vitritis

AIDS patients irrespective of location or severity

Drugs

1. Systemic steroids

2. Clindamycin

3. Sulphonamides

4. Pyrimethamide

5. Co-trimoxazole

6. Azithromycin

7. Atovaquone

Ocular toxocariasis

Always unilateral

Chronic endophthalmitis

Posterior pole granuloma

Presents between 2 to 9 years.

Presents between 6 to 14 years.

with leukocoria or strabismus

with visual loss

 

 

Optic nerve granuloma

Peripheral granuloma

Presents between 6 to14 years.

Presents during adolescence or

with visual loss

adult life with visual loss

Presumed ocular histoplasmosis syndrome

Fungal infection - Histoplasma capsulatum

Vitreous is never involved

Atrophic ‘histo’ spots

Peripapillary atrophy

 

 

 

 

Peripheral streaks

Choroidal

of chorioretinal atrophy

neovascularization

 

 

 

 

Candidiasis

Infection with yeast-like fungus - Candida albicans

Risk groups

Drug addicts or compromised host

Patients with long-term indwelling catheters

 

Progression

 

 

 

 

 

 

Unifocal choroiditis

Multifocal retinitis and vitreous

‘cotton-ball’ colonies

 

 

 

 

 

 

 

 

Endophthalmitis

 

Vitreoretinal traction

 

 

 

IDIOPATHIC SPECIFIC UVEITIS SYNDROMES

1.Fuchs uveitis syndrome

2.Intermediate uveitis

3.Juvenile chronic iridocyclitis

4.Acute anterior uveitis in young adults

5.Sympathetic ophthalmitis

Signs of Fuchs uveitis syndrome

Unilateral, chronic anterior uveitis

Resistant to therapy

KP - small and scattered No posterior synechiae

throughout endothelium

Diffuse iris stromal atrophy

Feathery fibrin filaments Occasionally iris nodules

Iris retroillumination

Heterochromia iridis -

 

affected eye is usually

 

hypochromic

Complications of Fuchs uveitis syndrome

Cataract

Angle new vessels

Glaucoma

Very common and

May bleed during

Uncommon but control

frequently

surgery

may be difficult

presenting feature

 

 

Intermediate uveitis

Typically affects children and young adults

Insidious and chronic

Frequently bilateral but asymmetrical

Usually presents with floaters

Vitritis

Vitreous snowballs

Mild peripheral

Snowbanking in pars

periphlebitis

planitis

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